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Gene: Pde11a (phosphodiesterase 11A) Rattus norvegicus

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Symbol:

Pde11a (Ensembl: Cyct)

Name:

phosphodiesterase 11A (Ensembl:cytochrome c, testis)

RGD ID:

621793

Description:

Predicted to enable 3',5'-cyclic-nucleotide phosphodiesterase activity and cGMP binding activity. Involved in negative regulation of cAMP/PKA signal transduction and negative regulation of cGMP-mediated signaling. Located in perikaryon. Human ortholog(s) of this gene implicated in primary pigmented nodular adrenocortical disease 2. Orthologous to human PDE11A (phosphodiesterase 11A); PARTICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; INTERACTS WITH 6-propyl-2-thiouracil; all-trans-retinoic acid; ammonium chloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cAMP and cGMP phosphodiesterase 11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; Pde11A2; Pde11A3; Pde11A4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PDE11A (phosphodiesterase 11A)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Pde11a (phosphodiesterase 11A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pde11a (phosphodiesterase 11A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LOC100982736 (dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PDE11A (phosphodiesterase 11A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pde11a (phosphodiesterase 11A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PDE11A (phosphodiesterase 11A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PDE11A (phosphodiesterase 11A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pde11a (phosphodiesterase 11A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pde11a (phosphodiesterase 11A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CYCS (cytochrome c, somatic)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	PDE11A (phosphodiesterase 11A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pde11a (phosphodiesterase 11A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pde11a (phosphodiesterase 11a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pde11al (phosphodiesterase 11a, like)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	PDE2	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	Pde11	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Pde11	Alliance	DIOPT (InParanoid\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pde11a	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)

Allele / Splice:

Pde11a_v3 ; Pde11a_v2 ; Pde11a_v1

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	81,320,822 - 81,704,397 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	81,320,822 - 81,680,612 (-)	Ensembl				GRCr8
mRatBN7.2	3	60,913,562 - 61,297,154 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	60,913,562 - 61,297,158 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	64,287,040 - 64,657,493 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	72,870,673 - 73,241,149 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	70,638,029 - 71,008,278 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	62,818,502 - 63,211,843 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	62,818,502 - 63,211,845 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	69,363,100 - 69,784,930 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	58,659,595 - 59,049,869 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	60,413,273 - 60,785,139 (-)	NCBI		Celera
RGSC_v3.1	3	58,555,966 - 58,922,151 (-)	NCBI
Cytogenetic Map	3	q23-q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bardet-Biedl syndrome 16 (ISO)

primary pigmented nodular adrenocortical disease 2 (ISO)

schizophrenia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dichloroethane (ISO)

3',5'-cyclic AMP (ISO)

3',5'-cyclic GMP (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-aminobenzohydrazide (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (EXP,ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

atrazine (EXP)

benzene-1,2,4-triol (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

caffeine (EXP)

cantharidin (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

cobalt dichloride (EXP)

cyproconazole (EXP)

D-glucose (ISO)

diazinon (EXP)

dipyridamole (ISO)

dorsomorphin (ISO)

flusilazole (EXP)

fructose (ISO)

fulvestrant (ISO)

glucose (ISO)

glyphosate (ISO)

hydroquinone (ISO)

methimazole (EXP)

methoxyacetic acid (EXP)

methoxychlor (EXP)

methylmercury chloride (EXP,ISO)

Monobutylphthalate (EXP)

O-methyleugenol (ISO)

okadaic acid (ISO)

panobinostat (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

thiram (ISO)

triadimefon (EXP)

trichostatin A (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of cAMP/PKA signal transduction (IBA,IDA)

negative regulation of receptor guanylyl cyclase signaling pathway (IBA,IDA)

signal transduction (IEA)

Cellular Component

cytosol (IEA)

perikaryon (IDA)

Molecular Function

3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity (IBA,IEA,ISO,ISS)

3',5'-cyclic-AMP phosphodiesterase activity (IBA,IEA)

3',5'-cyclic-GMP phosphodiesterase activity (IBA,IEA)

3',5'-cyclic-nucleotide phosphodiesterase activity (IEA)

catalytic activity (IEA)

cGMP binding (IEA,ISO)

hydrolase activity (IEA)

metal ion binding (IEA)

phosphoric diester hydrolase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

protein kinase A (PKA) signaling pathway (ISO)

purine metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling.	Conti M and Beavo J, Annu Rev Biochem. 2007;76:481-511.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	PDE9A, PDE10A, and PDE11A expression in rat trigeminovascular pain signalling system.	Kruse LS, etal., Brain Res. 2009 Jul 24;1281:25-34. Epub 2009 May 13.
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Identification of rat cyclic nucleotide phosphodiesterase 11A (PDE11A): comparison of rat and human PDE11A splicing variants.	Yuasa K, etal., Eur J Biochem 2001 Aug;268(16):4440-8.

Additional References at PubMed

PMID:2834389	PMID:17696499	PMID:19689430	PMID:31904090

Genomics

Comparative Map Data

Pde11a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	81,320,822 - 81,704,397 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	81,320,822 - 81,680,612 (-)	Ensembl				GRCr8
mRatBN7.2	3	60,913,562 - 61,297,154 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	60,913,562 - 61,297,158 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	64,287,040 - 64,657,493 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	72,870,673 - 73,241,149 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	70,638,029 - 71,008,278 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	62,818,502 - 63,211,843 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	62,818,502 - 63,211,845 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	69,363,100 - 69,784,930 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	58,659,595 - 59,049,869 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	60,413,273 - 60,785,139 (-)	NCBI		Celera
RGSC_v3.1	3	58,555,966 - 58,922,151 (-)	NCBI
Cytogenetic Map	3	q23-q24	NCBI

PDE11A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	177,623,244 - 178,108,339 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	177,623,244 - 178,108,339 (-)	Ensembl			hg38	GRCh38
GRCh37	2	178,487,972 - 178,973,066 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	178,196,223 - 178,681,312 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	178,318,318 - 178,762,989	NCBI
Celera	2	172,090,836 - 172,575,966 (-)	NCBI		Celera
Cytogenetic Map	2	q31.2	NCBI
HuRef	2	170,359,035 - 170,843,555 (-)	NCBI		HuRef
CHM1_1	2	178,493,788 - 178,979,175 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	178,105,555 - 178,591,096 (-)	NCBI		T2T-CHM13v2.0

Pde11a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	75,816,152 - 76,169,501 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	75,819,485 - 76,169,118 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	75,985,808 - 76,339,145 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	75,989,141 - 76,338,774 (-)	Ensembl			mm10	GRCm38
MGSCv37	2	75,829,189 - 76,176,710 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	75,791,561 - 76,139,492 (-)	NCBI		MGSCv36	mm8
Celera	2	77,652,941 - 78,004,820 (-)	NCBI		Celera
Cytogenetic Map	2	C3	NCBI
cM Map	2	44.8	NCBI

Pde11a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	18,804,789 - 19,180,612 (+)	Ensembl
ChiLan1.0	NW_004955403	18,804,789 - 19,180,612 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC100982736
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	80,289,127 - 80,564,300 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	80,307,862 - 80,579,274 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	64,903,170 - 65,332,922 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	182,605,628 - 183,038,353 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	182,611,762 - 183,038,353 (-)	Ensembl			panPan2	panpan1.1

PDE11A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	36	21,347,171 - 21,701,976 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	36	21,326,346 - 21,702,268 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	36	21,359,186 - 21,721,039 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	36	21,484,502 - 21,846,241 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	36	21,484,429 - 21,846,383 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	36	21,554,639 - 21,921,057 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	36	21,556,642 - 21,918,772 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	36	21,671,753 - 22,033,167 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pde11a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	138,389,843 - 138,768,230 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936509	6,948,710 - 7,322,156 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936509	6,943,758 - 7,322,192 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PDE11A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	83,365,723 - 83,757,934 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	83,366,082 - 83,784,266 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	93,138,914 - 93,295,087 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PDE11A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	63,183,716 - 63,649,030 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	63,185,043 - 63,614,749 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	136,120,068 - 136,395,287 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pde11a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624787	14,743,831 - 15,238,020 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624787	14,742,890 - 15,238,349 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pde11a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	53,343,509 - 53,566,879 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pde11a
2447 total Variants

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	51490129	111359995	Rat
1358293	Bw38	Body weight QTL 38	6	0.0000031	body mass (VT:0001259)	body weight (CMO:0000012)	3	74364268	119364268	Rat
61377	Edpm3	Estrogen-dependent pituitary mass QTL 3	7.05	0.038	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	73592611	110333156	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1331795	Rf30	Renal function QTL 30	3.708		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	3	59863663	87321459	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	73592512	136118980	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
1354589	Bw31	Body weight QTL 31	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	53651826	98651826	Rat
2303593	Gluco46	Glucose level QTL 46	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	48876619	93876619	Rat
1354590	Despr11	Despair related QTL 11		0.000031	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	3	48876619	93876619	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	35403199	97383526	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	58601291	153936591	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	49872657	138829559	Rat
631832	Sach1	Saccharin preference QTL 1	2.7	0.02	consumption behavior trait (VT:0002069)	calculated saccharin drink intake volume (CMO:0001600)	3	47904172	92904172	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1331777	Bw24	Body weight QTL 24	3.503		body mass (VT:0001259)	body weight (CMO:0000012)	3	59863663	87321459	Rat
631647	Bp122	Blood pressure QTL 122	6.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	51092561	96092561	Rat
1300169	Bp177	Blood pressure QTL 177	2.96		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	3	36425116	81425116	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	81425008	141509147	Rat
9590286	Uminl1	Urine mineral level QTL 1	3.5	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	3	48657744	93657744	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	70845569	136091483	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	37796919	82796919	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
2302276	Bw82	Body weight QTL 82	4.32		body mass (VT:0001259)	body weight (CMO:0000012)	3	59863663	83358329	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat
738019	Anxrr10	Anxiety related response QTL 10	3.9		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	3	58925062	103925062	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	70311536	115311536	Rat
631200	Cm25	Cardiac mass QTL 25	4.8	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	3	81541464	126563126	Rat
9590136	Scort3	Serum corticosterone level QTL 3	23.37	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	48657744	93657744	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	50766145	95766145	Rat
61356	Bp37	Blood pressure QTL 37	3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	51092561	96092561	Rat
1558650	Cm48	Cardiac mass QTL 48	4	0.0001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	3	50766145	95766145	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	36721849	110333156	Rat
8694196	Abfw2	Abdominal fat weight QTL 2	16.58	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	3	48657744	93657744	Rat
1582249	Bw77	Body weight QTL 77	3.2	0.0025	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	73592512	85062403	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	42158111	124558371	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
2325840	Bp345	Blood pressure QTL 345		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	38708931	83708931	Rat
8552950	Pigfal12	Plasma insulin-like growth factor 1 level QTL 12	7.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	48657744	93657744	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	37363734	82363734	Rat
8694386	Bw159	Body weight QTL 159	4.52	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	3	48657744	93657744	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	42158111	124558371	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat

Markers in Region

D3Rat38

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	3	81,541,464 - 81,541,596 (+)	Marker Load Pipeline
mRatBN7.2	3	61,134,216 - 61,134,348 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	63,048,919 - 63,049,050	NCBI	Rnor6.0
Rnor_5.0	3	69,593,794 - 69,593,925	UniSTS	Rnor5.0
RGSC_v3.4	3	58,882,846 - 58,882,977	UniSTS	RGSC3.4
RGSC_v3.4	3	58,882,845 - 58,882,977	RGD	RGSC3.4
Celera	3	60,631,503 - 60,631,634	UniSTS
RGSC_v3.1	3	58,779,217 - 58,779,349	RGD
SHRSP x BN Map	3	38.3398	UniSTS
SHRSP x BN Map	3	38.3398	RGD
Cytogenetic Map	3	q23	UniSTS

D3Rat180

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	3	81,425,008 - 81,425,116 (+)	Marker Load Pipeline
mRatBN7.2	3	61,017,749 - 61,017,857 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	62,922,868 - 62,922,975	NCBI	Rnor6.0
Rnor_5.0	3	69,467,333 - 69,467,440	UniSTS	Rnor5.0
RGSC_v3.4	3	58,764,514 - 58,764,621	UniSTS	RGSC3.4
RGSC_v3.4	3	58,764,506 - 58,764,827	RGD	RGSC3.4
Celera	3	60,517,624 - 60,517,731	UniSTS
RGSC_v3.1	3	58,660,878 - 58,661,199	RGD
SHRSP x BN Map	3	38.3798	UniSTS
SHRSP x BN Map	3	38.3798	RGD
Cytogenetic Map	3	q23	UniSTS

AU049636

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	61,283,491 - 61,283,674 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	63,198,181 - 63,198,363	NCBI	Rnor6.0
Rnor_5.0	3	69,737,516 - 69,737,698	UniSTS	Rnor5.0
RGSC_v3.4	3	59,036,207 - 59,036,389	UniSTS	RGSC3.4
Celera	3	60,771,474 - 60,771,659	UniSTS
Cytogenetic Map	3	q23	UniSTS

AU048155

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	61,130,022 - 61,130,228 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	63,044,725 - 63,044,930	NCBI	Rnor6.0
Rnor_5.0	3	69,589,600 - 69,589,805	UniSTS	Rnor5.0
RGSC_v3.4	3	58,878,652 - 58,878,857	UniSTS	RGSC3.4
Celera	3	60,627,309 - 60,627,514	UniSTS
Cytogenetic Map	3	q23	UniSTS

AU047925

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	62,837,571 - 62,837,827 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	67,304,185 - 67,304,440	NCBI	Rnor6.0
Rnor_5.0	8	67,038,196 - 67,038,451	UniSTS	Rnor5.0
Rnor_5.0	3	69,754,081 - 69,754,336	UniSTS	Rnor5.0
RGSC_v3.4	8	66,497,088 - 66,497,343	UniSTS	RGSC3.4
Celera	8	62,255,430 - 62,255,685	UniSTS
Cytogenetic Map	8	q24	UniSTS
Cytogenetic Map	3	q23	UniSTS

ANP32C__4314

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	61,291,940 - 61,292,660 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	63,206,630 - 63,207,349	NCBI	Rnor6.0
RGSC_v3.4	3	59,044,656 - 59,045,375	UniSTS	RGSC3.4
Celera	3	60,779,926 - 60,780,645	UniSTS
Cytogenetic Map	3	q23	UniSTS
Cytogenetic Map	8	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
10	2	25	64	64	154	99	12	60	45	60	27	27

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001127480	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001127481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_080893	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB059360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB059361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB059362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC129809	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000008301 ⟹ ENSRNOP00000008300

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	81,320,822 - 81,680,612 (-)	Ensembl
mRatBN7.2 Ensembl	3	60,913,571 - 61,273,339 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000008371 ⟹ ENSRNOP00000008371

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	61,290,090 - 61,297,158 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000045862 ⟹ ENSRNOP00000048657

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	81,320,822 - 81,586,733 (-)	Ensembl
mRatBN7.2 Ensembl	3	60,913,562 - 61,179,487 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000050355 ⟹ ENSRNOP00000051289

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	81,320,822 - 81,680,612 (-)	Ensembl
mRatBN7.2 Ensembl	3	60,913,562 - 61,297,156 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000127272 ⟹ ENSRNOP00000098745

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	81,320,822 - 81,680,612 (-)	Ensembl

RefSeq Acc Id:

NM_001127480 ⟹ NP_001120952

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	81,320,822 - 81,704,397 (-)	NCBI
mRatBN7.2	3	60,913,562 - 61,297,154 (-)	NCBI
Rnor_6.0	3	62,818,502 - 63,211,843 (-)	NCBI
Rnor_5.0	3	69,363,100 - 69,784,930 (-)	NCBI
RGSC_v3.4	3	58,659,595 - 59,049,869 (-)	RGD
Celera	3	60,413,273 - 60,785,139 (-)	RGD

Sequence:

show sequence

GCGGGGAGCGAGGATGGAGCCCGCCATCAGCTGGTGCATGATCCGGCCTGTAAGCGGAGTCCTC
GGGCACAGCAGTCGCGCCTTAAATCTTGGCCTCACTGCATCAGTGGACCAGGGGTGGCTCAGGG
CAGCGCTGCTGTGATCGTGAAAACAAAGAATAGGGAAACCAAGTCCAGGTTTGCAAATCTGAGA
CTTTTTTTGGTTGGTGATTTAAGGTTTTATTGCCGAGCAAAATGGGAGATGCTGAAGCAGGCAA
GAAGATTTTCATTCAGAAATGTGCGCAGTGCCACACAGTGGAGAAAGGTGGGAAGCACAAGACA
GGGCCAAATCTCTGGGGCCTTTTTGGCCGAAAGACTGGACAAGCACCAGGATTTTCTTACACGG
ATGCAAACAAGAACAAAGGACCGAAGATTCAATGATGAAATTGACAAGCTGACTGGATACAAGA
CAAAATCACTATTGTGCATGCCTATCCGGAACAGTGACGGTGAGATTATCGGTGTGGCCCAGGC
GATAAATAAGGTTCCTGAGGGTGCTCCATTTACAGAAGACGACGAAAAAGTTATGCAGATGTAT
CTTCCATTCTGTGGCATCGCCATATCTAATGCTCAGCTCTTCGCCGCCTCGAGGAAAGAATATG
AAAGAAGTAGGGCCTTGCTGGAGGTGGTCAATGACCTCTTTGAAGAACAGACTGACCTGGAAAA
GATTGTCAAGAAAATAATGCATCGGGCCCAAACTCTGTTGAAATGTGAACGCTGTTCCGTTTTA
CTTCTAGAAGACATTGAATCACCAGTGGTGAAGTTTACCAAATCCTTTGAACTGATGTCCCCAA
AGTGCAGTGCGGACGCGGAGAACAGTTTCAAAGAAAGTGTGGAGAAGTCATCTTACTCCGACTG
GCTGATAAATAACAGTATCGCTGAGCTGGTTGCTTCGACAGGCCTTCCTGTGAATGTCAGCGAT
GCCTACCAGGACCCACGCTTTGACGCTGAGGCTGACCAGATATCTGGCTTTCATATAAGATCTG
TTCTCTGTGTCCCTATTTGGAACAGCAACCACCAAATAATAGGGGTCGCTCAAGTGCTGAACAG
ACTCGATGGGAAACCTTTTGATGATGCTGACCAAAGGCTTTTTGAGGCCTTTGTCATCTTTTGT
GGCCTTGGTATTAACAACACGATTATGTATGACCAAGTGAAGAAGTCCTGGGCCAAGCAGTCCG
TGGCTCTTGATGTGCTGTCCTACCACGCCACGTGTTCCAAGGCTGAAGTTGACAAGTTTAAGGC
AGCCAACATCCCCCTGGTGTCGGAACTGGCCATCGATGACATCCATTTTGATGACTTTTCCCTT
GATGTTGATGCCATGATCACAGCCGCTCTACGGATGTTCATGGAGCTGGGGATGGTACAGAAAT
TTAAAATCGACTATGAGACCCTGTGCAGGTGGCTTCTGACAGTAAGGAAAAACTATCGGATGGT
TCTCTACCACAACTGGAGACATGCCTTCAACGTGTGCCAGCTGATGTTTGCCATGCTAACTACT
GCTGGGTTTCAAGAGATTCTGACCGAGGTGGAAATTTTAGCGGTGATTGTGGGATGCCTGTGTC
ATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGACTCTGCACTGGCCCA
GCTCTATGGGACCTCAGCGACCTTAGAGCATCACCACTTTAACCACGCCGTGATGATCCTTCAG
AGTGAGGGTCACAACATCTTTGCTAATTTGTCCTCCAAGGAATACAGCGACCTCATGCAGCTCC
TGAAGCAGTCGATACTAGCCACTGACCTCACGCTGTACTTCGAGAGAAGAACTGAGTTCTTCGA
GCTTGTCAGTAAAGGAGCCTATGATTGGAGCATCACAAGTCACCGCGATGTGTTTCGATCAATG
TTAATGACAGCTTGTGACCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCTG
AACTTGTCACCAGCGAGTTCTTCGAACAAGGAGATCGGGAGAGGTCGGAACTCAAGCTCACCCC
CTCTGCTATTTTTGACCGGAACCGGAAAGATGAGCTGCCTCGGCTGCAACTGGAGTGGATTGAC
AGCATCTGCATGCCTTTGTATCAGGCCTTGGTGAAAGTCAATGCAAAACTGAAGCCGATGCTGG
ACTCAGTGGCCGCCAACCGCAGGAAGTGGGAAGAGTTGCACCAAAAAAGACTACAGGTCTCTGC
TGCCTCCCCAGTCCCTTCCAGTCCCAGCCCAGCGGTGGCCGGAGAGGACAGACTGTAAACCACC
CAGAGCTGCTGCGCCACCCTGTGGCCTGGAGGACCCTCTGCATCCTGAACTATCTGCTTTGGTT
GAATAGCATCACCCTCTTCGTTCAGCTCGGACAGTCCTAAAGCTTTGACTGGATCAGGAAGCAC
ACAAGGAAGTGTGCTTGGCGGCAGAGAAACGGAAGGATGAAGAGAATACGACCCTCAACTTTGT
CATGAACCCATGCTGCTGGATTTGGATCCGTGGACCTGAAGGCCATCACCCCACTCGTGCTGAG
TTGAGAGGACACCGTTGTAAAAGTGTCACTATGGCTGCTTCCTGTATGGCACTTTTCTGTTATG
AGCATTTCCTTTCTGTGCAGCCTCTCCGGAGCAGGCTCCAGCCGGTCCCAAGAATGCAGATTTG
CATTCTAGGTGTTTTGTTTCTAATCTACTGCTTCTTTGTAATGCACCAGACCCTTCGTCTCCTT
TGCTAGTGGATAAGCCTGCTCCCTTTATTAGAGCCAGGTAACCCCAATCTTGCTTGCCACAGTA
GTAATATAGTGTGTTTGTCTAATTGGTGTTACACAGGAGCTGTAACTCTGCAGTGAGATAGATC
ATGGTTCAGCTTTTTAATTCAGCCTTTGTTGCAAACAAAGCCTTTTTCTAGGGGGAAACAGATT
AATAATTTTATTAAAGCAAAGGTGAAAAGGAATCTAAGGCCACATGTACAAGTGACATGTATGA
ACACCAGAAATGCTTCCAACAAAGAAATATTTCACAGGTGCAGAGGAACCCTGTGACCAGTCGT
GGAATAGTTTGAGGTGAAGGGGATGAAGGTTTGGGGATAAAATTTAAGGAACCCTGATTTTACA
TTTTTCCTTACATGTAAAAAAGAATGTTCTAGAAAGGCCAGGAAATAACACCTGCACAACCTAT
ATCCAGTAAGAAGTCAGATCTACAGCACGTGAAAACAGTTTTAAAGAGGTATGCTCACTAGAAA
GCTGCCTGAGACACTAAGGACAGGATCTGTCTTACCCAAAGAACATTGGGCTTCCTGTCCCTCA
CTTTGCATTACTAGTTGAGTGAGTTTGGACCTAGATTTCTCTGTGTCAAGCGAGATTACACTAG
GAATTTATTTGCAGTAATCTTAGCATTAAAATCTTTTGTCCAAATAAACTTCCAAGGATTCCCC
AGGGCACAAGGAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001127481 ⟹ NP_001120953

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	81,320,822 - 81,587,090 (-)	NCBI
mRatBN7.2	3	60,913,562 - 61,179,844 (-)	NCBI
Rnor_6.0	3	62,818,502 - 63,094,534 (-)	NCBI
Rnor_5.0	3	69,363,100 - 69,784,930 (-)	NCBI
RGSC_v3.4	3	58,659,595 - 59,049,869 (-)	RGD
Celera	3	60,413,273 - 60,677,634 (-)	NCBI

Sequence:

show sequence

GTACTTCCTCTGGCAAGGCTCCGCCTCCTGAAGGTTTCTTAACCTTCCTGAACTGTGCTATTAG
CTGGGGGCATCAAATGTTCAAAGATATGATCTTTCTCATCGTCCAGGGTAGCAGGATGAAGACT
ATGGCAAAGAGGAGTGGACAACAGAAGAATGAGCTGGGTTATGCAGATGTATCTTCCATTCTGT
GGCATCGCCATATCTAATGCTCAGCTCTTCGCCGCCTCGAGGAAAGAATATGAAAGAAGTAGGG
CCTTGCTGGAGGTGGTCAATGACCTCTTTGAAGAACAGACTGACCTGGAAAAGATTGTCAAGAA
AATAATGCATCGGGCCCAAACTCTGTTGAAATGTGAACGCTGTTCCGTTTTACTTCTAGAAGAC
ATTGAATCACCAGTGGTGAAGTTTACCAAATCCTTTGAACTGATGTCCCCAAAGTGCAGTGCGG
ACGCGGAGAACAGTTTCAAAGAAAGTGTGGAGAAGTCATCTTACTCCGACTGGCTGATAAATAA
CAGTATCGCTGAGCTGGTTGCTTCGACAGGCCTTCCTGTGAATGTCAGCGATGCCTACCAGGAC
CCACGCTTTGACGCTGAGGCTGACCAGATATCTGGCTTTCATATAAGATCTGTTCTCTGTGTCC
CTATTTGGAACAGCAACCACCAAATAATAGGGGTCGCTCAAGTGCTGAACAGACTCGATGGGAA
ACCTTTTGATGATGCTGACCAAAGGCTTTTTGAGGCCTTTGTCATCTTTTGTGGCCTTGGTATT
AACAACACGATTATGTATGACCAAGTGAAGAAGTCCTGGGCCAAGCAGTCCGTGGCTCTTGATG
TGCTGTCCTACCACGCCACGTGTTCCAAGGCTGAAGTTGACAAGTTTAAGGCAGCCAACATCCC
CCTGGTGTCGGAACTGGCCATCGATGACATCCATTTTGATGACTTTTCCCTTGATGTTGATGCC
ATGATCACAGCCGCTCTACGGATGTTCATGGAGCTGGGGATGGTACAGAAATTTAAAATCGACT
ATGAGACCCTGTGCAGGTGGCTTCTGACAGTAAGGAAAAACTATCGGATGGTTCTCTACCACAA
CTGGAGACATGCCTTCAACGTGTGCCAGCTGATGTTTGCCATGCTAACTACTGCTGGGTTTCAA
GAGATTCTGACCGAGGTGGAAATTTTAGCGGTGATTGTGGGATGCCTGTGTCATGACCTCGACC
ACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGACTCTGCACTGGCCCAGCTCTATGGGAC
CTCAGCGACCTTAGAGCATCACCACTTTAACCACGCCGTGATGATCCTTCAGAGTGAGGGTCAC
AACATCTTTGCTAATTTGTCCTCCAAGGAATACAGCGACCTCATGCAGCTCCTGAAGCAGTCGA
TACTAGCCACTGACCTCACGCTGTACTTCGAGAGAAGAACTGAGTTCTTCGAGCTTGTCAGTAA
AGGAGCCTATGATTGGAGCATCACAAGTCACCGCGATGTGTTTCGATCAATGTTAATGACAGCT
TGTGACCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCTGAACTTGTCACCA
GCGAGTTCTTCGAACAAGGAGATCGGGAGAGGTCGGAACTCAAGCTCACCCCCTCTGCTATTTT
TGACCGGAACCGGAAAGATGAGCTGCCTCGGCTGCAACTGGAGTGGATTGACAGCATCTGCATG
CCTTTGTATCAGGCCTTGGTGAAAGTCAATGCAAAACTGAAGCCGATGCTGGACTCAGTGGCCG
CCAACCGCAGGAAGTGGGAAGAGTTGCACCAAAAAAGACTACAGGTCTCTGCTGCCTCCCCAGT
CCCTTCCAGTCCCAGCCCAGCGGTGGCCGGAGAGGACAGACTGTAAACCACCCAGAGCTGCTGC
GCCACCCTGTGGCCTGGAGGACCCTCTGCATCCTGAACTATCTGCTTTGGTTGAATAGCATCAC
CCTCTTCGTTCAGCTCGGACAGTCCTAAAGCTTTGACTGGATCAGGAAGCACACAAGGAAGTGT
GCTTGGCGGCAGAGAAACGGAAGGATGAAGAGAATACGACCCTCAACTTTGTCATGAACCCATG
CTGCTGGATTTGGATCCGTGGACCTGAAGGCCATCACCCCACTCGTGCTGAGTTGAGAGGACAC
CGTTGTAAAAGTGTCACTATGGCTGCTTCCTGTATGGCACTTTTCTGTTATGAGCATTTCCTTT
CTGTGCAGCCTCTCCGGAGCAGGCTCCAGCCGGTCCCAAGAATGCAGATTTGCATTCTAGGTGT
TTTGTTTCTAATCTACTGCTTCTTTGTAATGCACCAGACCCTTCGTCTCCTTTGCTAGTGGATA
AGCCTGCTCCCTTTATTAGAGCCAGGTAACCCCAATCTTGCTTGCCACAGTAGTAATATAGTGT
GTTTGTCTAATTGGTGTTACACAGGAGCTGTAACTCTGCAGTGAGATAGATCATGGTTCAGCTT
TTTAATTCAGCCTTTGTTGCAAACAAAGCCTTTTTCTAGGGGGAAACAGATTAATAATTTTATT
AAAGCAAAGGTGAAAAGGAATCTAAGGCCACATGTACAAGTGACATGTATGAACACCAGAAATG
CTTCCAACAAAGAAATATTTCACAGGTGCAGAGGAACCCTGTGACCAGTCGTGGAATAGTTTGA
GGTGAAGGGGATGAAGGTTTGGGGATAAAATTTAAGGAACCCTGATTTTACATTTTTCCTTACA
TGTAAAAAAGAATGTTCTAGAAAGGCCAGGAAATAACACCTGCACAACCTATATCCAGTAAGAA
GTCAGATCTACAGCACGTGAAAACAGTTTTAAAGAGGTATGCTCACTAGAAAGCTGCCTGAGAC
ACTAAGGACAGGATCTGTCTTACCCAAAGAACATTGGGCTTCCTGTCCCTCACTTTGCATTACT
AGTTGAGTGAGTTTGGACCTAGATTTCTCTGTGTCAAGCGAGATTACACTAGGAATTTATTTGC
AGTAATCTTAGCATTAAAATCTTTTGTCCAAATAAACTTCCAAGGATTCCCCAGGGCACAAGGA
AAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_080893 ⟹ NP_543169

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	81,320,822 - 81,680,612 (-)	NCBI
mRatBN7.2	3	60,913,562 - 61,273,369 (-)	NCBI
Rnor_6.0	3	62,818,502 - 63,188,028 (-)	NCBI
Rnor_5.0	3	69,363,100 - 69,784,930 (-)	NCBI
RGSC_v3.4	3	58,659,595 - 59,049,869 (-)	RGD
Celera	3	60,413,273 - 60,761,181 (-)	NCBI

Sequence:

show sequence

CAATCGGGATCCTGCTGTTCCTTTCAACCTCCGGTTGGCTGGTGGGGAGGTAGTACCGAGCTGG
GGACACGGGTGTGGGCAAACATGTGCAGCAACAACTAGAGGCCTCAGGACAGGTTAACGTGTGG
GTCCCAGAGTAGAGAGGCGAAGCAAGGGGTGCCCGGGACCATGGCAGCCTCCCGCCTGGACTTC
GGGGAGGTGGAAACTTTCCTGGATAGGCACCCAGAATTGTTTGAAGATTACTTGATGCGAAAAG
GAAAGCAGGAGCTGGTGGACAAGTGGCTACAAAGGCACAGTTCGGGACAGGGGGCTTCAGACCT
GAGGCCTGCCCTGGCTGGCGCTAGCAGCTTGGCTCAGAGCAGTGCCAGAGGCAGCACTGGCATA
GGTGGTGGTGCTGGACCCCAGGGTTCTGCCAACAGTCATCCCGCGTCCGGTGGTGGGGAAAGTG
CCGGGGTTCCTCTGAGTCCCAGTTGGGCCAGTGGCAGCCGGGGCGATGGCAACCTTCAGAGGAG
AGCTTCGCAGAAAGAGCTGAGAAAGAGCTTTGCCCGCTCCAAAGCCATCCATGTGAACAGGACC
TACGACGAACAGGTGACCTCCCGGGCCCAGGAGCCCCTGAGCAGTGTCCGGAGGCGAGCCCTGC
TCAGAAAGGCCAGCTCTCTGCCCCCCACCACAGCCCACATTCTCAGTGCCCTGCTGGAATCGAG
GGTGAATCTTCCTCAGTATCCCCCTACGGCCATCGACTACAAATGCCACCTCAAAAAGCATAAT
GAGCGACAGTTTTTCCTGGAACTGGTCAAGGACATCTCCAATGACCTTGACCTCACCAGCCTAA
GCTACAAGATCCTCATCTTTGTCTGTCTCATGGTGGACGCTGACCGCTGCTCTCTCTTCTTAGT
GGAAGGGGCAGCTGCTGGTAAGAAGACTTTGGTCTCCAAGTTTTTTGACGTGCATGCAGGAACC
CCACTGCTGCCCTGCAGCACCACAGAGAACTCAAATGAGGTGCAGGTCCCCTGGGGCAAAGGTA
TCATTGGCTATGTCGGGGAACACGGAGAAACAGTCAACATTCCCGATGCCTACCAGGACCGAAG
ATTCAATGATGAAATTGACAAGCTGACTGGATACAAGACAAAATCACTATTGTGCATGCCTATC
CGGAACAGTGACGGTGAGATTATCGGTGTGGCCCAGGCGATAAATAAGGTTCCTGAGGGTGCTC
CATTTACAGAAGACGACGAAAAAGTTATGCAGATGTATCTTCCATTCTGTGGCATCGCCATATC
TAATGCTCAGCTCTTCGCCGCCTCGAGGAAAGAATATGAAAGAAGTAGGGCCTTGCTGGAGGTG
GTCAATGACCTCTTTGAAGAACAGACTGACCTGGAAAAGATTGTCAAGAAAATAATGCATCGGG
CCCAAACTCTGTTGAAATGTGAACGCTGTTCCGTTTTACTTCTAGAAGACATTGAATCACCAGT
GGTGAAGTTTACCAAATCCTTTGAACTGATGTCCCCAAAGTGCAGTGCGGACGCGGAGAACAGT
TTCAAAGAAAGTGTGGAGAAGTCATCTTACTCCGACTGGCTGATAAATAACAGTATCGCTGAGC
TGGTTGCTTCGACAGGCCTTCCTGTGAATGTCAGCGATGCCTACCAGGACCCACGCTTTGACGC
TGAGGCTGACCAGATATCTGGCTTTCATATAAGATCTGTTCTCTGTGTCCCTATTTGGAACAGC
AACCACCAAATAATAGGGGTCGCTCAAGTGCTGAACAGACTCGATGGGAAACCTTTTGATGATG
CTGACCAAAGGCTTTTTGAGGCCTTTGTCATCTTTTGTGGCCTTGGTATTAACAACACGATTAT
GTATGACCAAGTGAAGAAGTCCTGGGCCAAGCAGTCCGTGGCTCTTGATGTGCTGTCCTACCAC
GCCACGTGTTCCAAGGCTGAAGTTGACAAGTTTAAGGCAGCCAACATCCCCCTGGTGTCGGAAC
TGGCCATCGATGACATCCATTTTGATGACTTTTCCCTTGATGTTGATGCCATGATCACAGCCGC
TCTACGGATGTTCATGGAGCTGGGGATGGTACAGAAATTTAAAATCGACTATGAGACCCTGTGC
AGGTGGCTTCTGACAGTAAGGAAAAACTATCGGATGGTTCTCTACCACAACTGGAGACATGCCT
TCAACGTGTGCCAGCTGATGTTTGCCATGCTAACTACTGCTGGGTTTCAAGAGATTCTGACCGA
GGTGGAAATTTTAGCGGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAAC
AATGCCTTCCAAGCTAAGAGTGACTCTGCACTGGCCCAGCTCTATGGGACCTCAGCGACCTTAG
AGCATCACCACTTTAACCACGCCGTGATGATCCTTCAGAGTGAGGGTCACAACATCTTTGCTAA
TTTGTCCTCCAAGGAATACAGCGACCTCATGCAGCTCCTGAAGCAGTCGATACTAGCCACTGAC
CTCACGCTGTACTTCGAGAGAAGAACTGAGTTCTTCGAGCTTGTCAGTAAAGGAGCCTATGATT
GGAGCATCACAAGTCACCGCGATGTGTTTCGATCAATGTTAATGACAGCTTGTGACCTTGGAGC
CGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCTGAACTTGTCACCAGCGAGTTCTTCGAA
CAAGGAGATCGGGAGAGGTCGGAACTCAAGCTCACCCCCTCTGCTATTTTTGACCGGAACCGGA
AAGATGAGCTGCCTCGGCTGCAACTGGAGTGGATTGACAGCATCTGCATGCCTTTGTATCAGGC
CTTGGTGAAAGTCAATGCAAAACTGAAGCCGATGCTGGACTCAGTGGCCGCCAACCGCAGGAAG
TGGGAAGAGTTGCACCAAAAAAGACTACAGGTCTCTGCTGCCTCCCCAGTCCCTTCCAGTCCCA
GCCCAGCGGTGGCCGGAGAGGACAGACTGTAAACCACCCAGAGCTGCTGCGCCACCCTGTGGCC
TGGAGGACCCTCTGCATCCTGAACTATCTGCTTTGGTTGAATAGCATCACCCTCTTCGTTCAGC
TCGGACAGTCCTAAAGCTTTGACTGGATCAGGAAGCACACAAGGAAGTGTGCTTGGCGGCAGAG
AAACGGAAGGATGAAGAGAATACGACCCTCAACTTTGTCATGAACCCATGCTGCTGGATTTGGA
TCCGTGGACCTGAAGGCCATCACCCCACTCGTGCTGAGTTGAGAGGACACCGTTGTAAAAGTGT
CACTATGGCTGCTTCCTGTATGGCACTTTTCTGTTATGAGCATTTCCTTTCTGTGCAGCCTCTC
CGGAGCAGGCTCCAGCCGGTCCCAAGAATGCAGATTTGCATTCTAGGTGTTTTGTTTCTAATCT
ACTGCTTCTTTGTAATGCACCAGACCCTTCGTCTCCTTTGCTAGTGGATAAGCCTGCTCCCTTT
ATTAGAGCCAGGTAACCCCAATCTTGCTTGCCACAGTAGTAATATAGTGTGTTTGTCTAATTGG
TGTTACACAGGAGCTGTAACTCTGCAGTGAGATAGATCATGGTTCAGCTTTTTAATTCAGCCTT
TGTTGCAAACAAAGCCTTTTTCTAGGGGGAAACAGATTAATAATTTTATTAAAGCAAAGGTGAA
AAGGAATCTAAGGCCACATGTACAAGTGACATGTATGAACACCAGAAATGCTTCCAACAAAGAA
ATATTTCACAGGTGCAGAGGAACCCTGTGACCAGTCGTGGAATAGTTTGAGGTGAAGGGGATGA
AGGTTTGGGGATAAAATTTAAGGAACCCTGATTTTACATTTTTCCTTACATGTAAAAAAGAATG
TTCTAGAAAGGCCAGGAAATAACACCTGCACAACCTATATCCAGTAAGAAGTCAGATCTACAGC
ACGTGAAAACAGTTTTAAAGAGGTATGCTCACTAGAAAGCTGCCTGAGACACTAAGGACAGGAT
CTGTCTTACCCAAAGAACATTGGGCTTCCTGTCCCTCACTTTGCATTACTAGTTGAGTGAGTTT
GGACCTAGATTTCTCTGTGTCAAGCGAGATTACACTAGGAATTTATTTGCAGTAATCTTAGCAT
TAAAATCTTTTGTCCAAATAAACTTCCAAGGATTCCCCAGGGCACAAGGAAAAAAAAAAAAAAA
AAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001120952	(Get FASTA)	NCBI Sequence Viewer
	NP_001120953	(Get FASTA)	NCBI Sequence Viewer
	NP_543169	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAB79627	(Get FASTA)	NCBI Sequence Viewer
	BAB79628	(Get FASTA)	NCBI Sequence Viewer
	BAB79629	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000008300
	ENSRNOP00000048657
	ENSRNOP00000048657.2
	ENSRNOP00000051289.1
GenBank Protein	Q8VID6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_543169 ⟸ NM_080893
- Peptide Label:	isoform 4
- UniProtKB:	Q8VID7 (UniProtKB/Swiss-Prot), Q8VID8 (UniProtKB/Swiss-Prot), Q8VID6 (UniProtKB/Swiss-Prot), A0A8L2Q3C3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAASRLDFGEVETFLDRHPELFEDYLMRKGKQELVDKWLQRHSSGQGASDLRPALAGASSLAQS SARGSTGIGGGAGPQGSANSHPASGGGESAGVPLSPSWASGSRGDGNLQRRASQKELRKSFARS KAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPQYPPTAIDY KCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAAAGKKTLVSK FFDVHAGTPLLPCSTTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKT KSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYE RSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPK CSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISGFHIRSV LCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSV ALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKF KIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCH DLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLL KQSILATDLTLYFERRTEFFELVSKGAYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAE LVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLD SVAANRRKWEELHQKRLQVSAASPVPSSPSPAVAGEDRL hide sequence

RefSeq Acc Id:	NP_001120952 ⟸ NM_001127480
- Peptide Label:	isoform 3
- UniProtKB:	Q8VID6 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MLKQARRFSFRNVRSATQWRKVGSTRQGQISGAFLAERLDKHQDFLTRMQTRTKDRRFNDEIDK LTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAA SRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSF ELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISG FHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKS WAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMEL GMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVI VGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYS DLMQLLKQSILATDLTLYFERRTEFFELVSKGAYDWSITSHRDVFRSMLMTACDLGAVTKPWEI SRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAK LKPMLDSVAANRRKWEELHQKRLQVSAASPVPSSPSPAVAGEDRL hide sequence

RefSeq Acc Id:	NP_001120953 ⟸ NM_001127481
- Peptide Label:	isoform 2
- UniProtKB:	Q8VID6 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MSWVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLL KCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVAST GLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRL FEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDD IHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQ LMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHF NHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGAYDWSITS HRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELP RLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAANRRKWEELHQKRLQVSAASPVPSSPSPAVA GEDRL hide sequence

Ensembl Acc Id:

ENSRNOP00000051289 ⟸ ENSRNOT00000050355

Ensembl Acc Id:

ENSRNOP00000008300 ⟸ ENSRNOT00000008301

Ensembl Acc Id:

ENSRNOP00000008371 ⟸ ENSRNOT00000008371

Ensembl Acc Id:

ENSRNOP00000048657 ⟸ ENSRNOT00000045862

Ensembl Acc Id:

ENSRNOP00000098745 ⟸ ENSRNOT00000127272

Protein Domains

GAF PDEase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8VID6-F1-model_v2	AlphaFold	Q8VID6	1-935	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621793	AgrOrtholog
BioCyc Gene	G2FUF-49293	BioCyc
Ensembl Genes	ENSRNOG00000024457	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000008301	ENTREZGENE
	ENSRNOT00000045862	ENTREZGENE
	ENSRNOT00000045862.3	UniProtKB/Swiss-Prot
	ENSRNOT00000050355.4	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.1300.10	UniProtKB/Swiss-Prot
	3.30.450.40	UniProtKB/Swiss-Prot
InterPro	GAF	UniProtKB/Swiss-Prot
	GAF-like_dom_sf	UniProtKB/Swiss-Prot
	HD/PDEase_dom	UniProtKB/Swiss-Prot
	PDEase	UniProtKB/Swiss-Prot
	PDEase_catalytic_dom	UniProtKB/Swiss-Prot
	PDEase_catalytic_dom_sf	UniProtKB/Swiss-Prot
	PDEase_CS	UniProtKB/Swiss-Prot
KEGG Report	rno:140928	UniProtKB/Swiss-Prot
NCBI Gene	140928	ENTREZGENE
PANTHER	CYCLIC NUCLEOTIDE PHOSPHODIESTERASE	UniProtKB/Swiss-Prot
Pfam	GAF	UniProtKB/Swiss-Prot
	PDEase_I	UniProtKB/Swiss-Prot
PhenoGen	Pde11a	PhenoGen
PRINTS	PDIESTERASE1	UniProtKB/Swiss-Prot
PROSITE	PDEASE_I_1	UniProtKB/Swiss-Prot
	PDEASE_I_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000024457	RatGTEx
SMART	GAF	UniProtKB/Swiss-Prot
	HDc	UniProtKB/Swiss-Prot
Superfamily-SCOP	GAF domain-like	UniProtKB/Swiss-Prot
	HD-domain/PDEase-like	UniProtKB/Swiss-Prot
UniProt	A0A8L2Q3C3	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L533_RAT	UniProtKB/TrEMBL
	PDE11_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q8VID7	ENTREZGENE
	Q8VID8	ENTREZGENE
UniProt Secondary	Q8VID7	UniProtKB/Swiss-Prot
	Q8VID8	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Description	Reference	Status
2005-01-20	Pde11a	phosphodiesterase 11A	Symbol and Name status set to approved	1299863	APPROVED
2004-12-14	Pde11a	phosphodiesterase 11A	Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Pde11a	phosphodiesterase 11A	Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
null	has several splice variant products which exhibit differences in cyclic nucleotide phosphodiesterase activity toward cAMP and cGMP characterized as similar Km values but differing Vmax values
gene_function	has several splice variant products which exhibit differences in cyclic nucleotide phosphodiesterase activity toward cAMP and cGMP characterized as similar Km values but differing Vmax values	633590

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)