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Gene: Ppp1r3d (protein phosphatase 1, regulatory subunit 3D) Rattus norvegicus

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Symbol:

Ppp1r3d

Name:

protein phosphatase 1, regulatory subunit 3D

RGD ID:

1586306

Description:

Enables enzyme binding activity. Contributes to phosphoprotein phosphatase activity. Involved in regulation of glycogen biosynthetic process and regulation of glycogen catabolic process. Located in glycogen granule. Orthologous to human PPP1R3D (protein phosphatase 1 regulatory subunit 3D); PARTICIPATES IN glycogen biosynthetic pathway; glycogen degradation pathway; adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; acetamide; alpha-Zearalanol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC689995; protein phosphatase 1 regulatory subunit 3D; similar to Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1, regulatory subunit 6) (Protein phosphatase 1-binding subunit R6)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PPP1R3D (protein phosphatase 1 regulatory subunit 3D)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Ppp1r3d (protein phosphatase 1, regulatory subunit 3D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ppp1r3d (protein phosphatase 1 regulatory subunit 3D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PPP1R3D (protein phosphatase 1 regulatory subunit 3D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PPP1R3D (protein phosphatase 1 regulatory subunit 3D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ppp1r3d (protein phosphatase 1 regulatory subunit 3D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PPP1R3D (protein phosphatase 1 regulatory subunit 3D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PPP1R3D (protein phosphatase 1 regulatory subunit 3D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ppp1r3d (protein phosphatase 1 regulatory subunit 3D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ppp1r3d (protein phosphatase 1 regulatory subunit 3D)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PTPN2 (protein tyrosine phosphatase non-receptor type 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PPP1R3D (protein phosphatase 1 regulatory subunit 3D)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ppp1r3d (protein phosphatase 1, regulatory subunit 3D)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ppp1r3da (protein phosphatase 1, regulatory subunit 3Da)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ppp1r3db (protein phosphatase 1, regulatory subunit 3Db)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GAC1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	GAC1	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Caenorhabditis elegans (roundworm):	CC8.2	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector)
Caenorhabditis elegans (roundworm):	CC8.2	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	Gbs-76A	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Gbs-76A	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	GIP2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	PIG2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	PIG1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	PIG1	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	ppp1r3d	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	185,880,087 - 185,883,158 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	185,876,709 - 185,883,703 (-)	Ensembl				GRCr8
mRatBN7.2	3	165,502,384 - 165,505,455 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	165,502,384 - 165,505,455 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	169,876,489 - 169,879,560 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	178,835,577 - 178,838,648 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	175,501,947 - 175,505,018 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	173,950,613 - 173,953,684 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	173,950,613 - 173,953,684 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	183,137,515 - 183,140,586 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	167,505,678 - 167,508,749 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	167,056,456 - 167,059,527 (+)	NCBI		Celera
Cytogenetic Map	3	q43	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2-hydroxypropanoic acid (ISO)

acetamide (EXP)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

arsenous acid (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP)

cantharidin (ISO)

carbon nanotube (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

formaldehyde (ISO)

FR900359 (ISO)

furan (EXP)

gentamycin (EXP)

panobinostat (ISO)

paracetamol (ISO)

perfluorooctanoic acid (EXP)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

SB 431542 (ISO)

tetrachloromethane (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (EXP,ISO)

Triptolide (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glycogen metabolic process (IEA)

regulation of glycogen biosynthetic process (IBA,IDA)

regulation of glycogen catabolic process (IDA)

Cellular Component

glycogen granule (IDA)

protein phosphatase type 1 complex (IBA)

Molecular Function

enzyme binding (IMP)

glycogen binding (IBA)

phosphoprotein phosphatase activity (IDA,IEA)

protein binding (ISO)

protein phosphatase 1 binding (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

adenosine monophosphate-activated protein kinase (AMPK) signaling pathway (ISO)

glycogen biosynthetic pathway (IDA)

glycogen degradation pathway (IDA)

insulin signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	The level of the glycogen targetting regulatory subunit R5 of protein phosphatase 1 is decreased in the livers of insulin-dependent diabetic rats and starved rats.	Browne GJ, etal., Biochem J. 2001 Dec 1;360(Pt 2):449-59.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	AMP-activated protein kinase: also regulated by ADP?	Hardie DG, etal., Trends Biochem Sci. 2011 Sep;36(9):470-7. doi: 10.1016/j.tibs.2011.06.004. Epub 2011 Jul 23.
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Ppp1r3d
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	185,880,087 - 185,883,158 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	185,876,709 - 185,883,703 (-)	Ensembl				GRCr8
mRatBN7.2	3	165,502,384 - 165,505,455 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	165,502,384 - 165,505,455 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	169,876,489 - 169,879,560 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	178,835,577 - 178,838,648 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	175,501,947 - 175,505,018 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	173,950,613 - 173,953,684 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	173,950,613 - 173,953,684 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	183,137,515 - 183,140,586 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	167,505,678 - 167,508,749 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	167,056,456 - 167,059,527 (+)	NCBI		Celera
Cytogenetic Map	3	q43	NCBI

PPP1R3D
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	59,936,663 - 59,940,305 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	59,936,663 - 59,940,305 (-)	Ensembl			hg38	GRCh38
GRCh37	20	58,511,718 - 58,515,360 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	57,945,282 - 57,948,747 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	57,945,282 - 57,948,747	NCBI
Celera	20	55,252,565 - 55,256,030 (-)	NCBI		Celera
Cytogenetic Map	20	q13.33	NCBI
HuRef	20	55,299,100 - 55,302,565 (-)	NCBI		HuRef
CHM1_1	20	58,412,949 - 58,416,414 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	20	61,720,935 - 61,724,577 (-)	NCBI		T2T-CHM13v2.0

Ppp1r3d
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	178,052,999 - 178,056,256 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	178,052,999 - 178,056,265 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	178,411,206 - 178,414,463 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	178,411,206 - 178,414,472 (-)	Ensembl			mm10	GRCm38
MGSCv37	2	178,145,911 - 178,149,177 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	178,340,614 - 178,343,929 (-)	NCBI		MGSCv36	mm8
Celera	2	182,497,614 - 182,500,880 (-)	NCBI		Celera
Cytogenetic Map	2	H4	NCBI
cM Map	2	99.91	NCBI

Ppp1r3d
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955528	3,804,557 - 3,807,309 (+)	NCBI	ChiLan1.0	ChiLan1.0

PPP1R3D
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	65,705,083 - 65,708,325 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	65,698,203 - 65,701,298 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	56,292,457 - 56,295,977 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	57,644,184 - 57,647,585 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

PPP1R3D
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	44,550,028 - 44,551,556 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	44,550,320 - 44,551,219 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	43,794,436 - 43,795,617 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	45,416,651 - 45,417,832 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	45,416,933 - 45,417,832 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	44,518,184 - 44,519,364 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	44,637,780 - 44,638,960 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	45,297,767 - 45,298,948 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ppp1r3d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	192,897,627 - 192,900,141 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	8,352,513 - 8,353,409 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	8,350,275 - 8,353,782 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPP1R3D
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	59,964,585 - 59,967,113 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	59,963,560 - 59,967,143 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	67,406,676 - 67,409,825 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPP1R3D
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	4,207,963 - 4,211,630 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	4,208,351 - 4,209,250 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	52,250,088 - 52,253,648 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppp1r3d
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	26,207,096 - 26,207,827 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624741	26,205,076 - 26,208,158 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ppp1r3d
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	155,479,194 - 155,482,291 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	268
Count of miRNA genes:	172
Interacting mature miRNAs:	214
Transcripts:	ENSRNOT00000075411
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141555229	186555229	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	141555229	186555229	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	142898802	187898802	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	141555229	186555229	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	141555229	186555229	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	141555229	186555229	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	161492708	189428310	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	141555229	186555229	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1300161	Rf10	Renal function QTL 10	3.57		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	3	181611379	189428310	Rat
8552791	Vie2	Viral induced encephalitis QTL 2	4.1		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	3	166376089	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	161799270	187311134	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	141555229	186555229	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1598854	Memor10	Memory QTL 10	2		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	3	166376089	189428310	Rat

Markers in Region

RH134110

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	165,502,641 - 165,502,842 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	173,950,871 - 173,951,071	NCBI	Rnor6.0
Rnor_5.0	3	183,140,128 - 183,140,328	UniSTS	Rnor5.0
RGSC_v3.4	3	167,505,936 - 167,506,136	UniSTS	RGSC3.4
Celera	3	167,059,069 - 167,059,269	UniSTS
RH 3.4 Map	3	1501.0	UniSTS
Cytogenetic Map	3	q43	UniSTS

RH143923

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	165,505,177 - 165,505,299 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	173,953,407 - 173,953,528	NCBI	Rnor6.0
Rnor_5.0	3	183,137,671 - 183,137,792	UniSTS	Rnor5.0
RGSC_v3.4	3	167,508,472 - 167,508,593	UniSTS	RGSC3.4
Celera	3	167,056,612 - 167,056,733	UniSTS
RH 3.4 Map	3	1510.89	UniSTS
Cytogenetic Map	3	q43	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC127963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000090468 ⟹ ENSRNOP00000068843

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	185,878,682 - 185,883,161 (-)	Ensembl
mRatBN7.2 Ensembl	3	165,502,384 - 165,505,455 (-)	Ensembl
Rnor_6.0 Ensembl	3	173,950,613 - 173,953,684 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000091212 ⟹ ENSRNOP00000072427

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	185,876,709 - 185,883,703 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000170588 ⟹ ENSRNOP00000101831

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	185,877,808 - 185,883,694 (-)	Ensembl

RefSeq Acc Id:

NM_001109564 ⟹ NP_001103034

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	185,880,087 - 185,883,158 (-)	NCBI
mRatBN7.2	3	165,502,384 - 165,505,455 (-)	NCBI
Rnor_6.0	3	173,950,613 - 173,953,684 (-)	NCBI
Rnor_5.0	3	183,137,515 - 183,140,586 (+)	NCBI
RGSC_v3.4	3	167,505,678 - 167,508,749 (-)	RGD
Celera	3	167,056,456 - 167,059,527 (+)	RGD

Sequence:

show sequence

AGCGTCTAGGCGGCGGGGTTCCCGGCCTTCCCGTAAGCCCTCGAAGGAAGGGGAGAAGCAGGCG
CCACCGTGCAGGACGCAACGCCCCGGGAAGCTGCCTTGAAGAGCGCCACCCACCGCTCCAGACT
GTCCGCCGCTGAGACGCCGGCCAGGCCGCGAGCACAGTCTCCGTGTTGGGTGCGGTGCCTCAGG
GCTCCCAGAGGCTGTCCAGCCCTAACGCCCAGTGGCTCGGCGGTGACACCAGCCCAGCTGGGCC
ATGTCAAAAGGCCCTGATTCTGCCCTGCTGCCCTCGACCCCGGGACCCCGGAAACTCGCACCCC
GGAGCCTCAGCTGCCTCTCGGACATGGATGGACGATCCTGCAGACCCCCGGGCTGTGACCCTCG
CCTGCGGCCCATCATCCAACGACGCTCGCGCTCTCTGCCCACCTCCCCTGAGCGCCGTGCCAAG
GCTGCAGGAGCCCAGGGCGCCGCGTGCGGAGCCGGCTGCAACCGGCAGGTCCGAGTGCGCTTCG
CTGACGCGCTGGGCCTGGAACTGGCGCAGGTCAAGGTGTTTAACGCAGGCGATGACCCGTCCGT
GCCGCTGCACGTGCTGTCGCGCCTAGCCATCAACTCGGATTTGTGCTGCAGTAGCCAGGATCTG
GAGTTCACACTGCAGTGCCTGGTTCCTGACTTCCAGCCGCCCATCGAAGTCCCGGGCTTCGGAG
ATCGCCTGGCGCGGCAGCTCGTATGCCTGGAACGTGTCACCTGCTCCGACCTAGGCATCAGTGG
CACAGTGCGCGTGCGCAACGTGGCGTTCGAGAAGCAGGTGACGGTGCGCTACACCTTCTCTGGC
TGGCGCAGTGCGCACGAAGCAGTGGCGCGCTGGAGAGGGCCTGCGGGTGGTGAAGGTACCGAGG
ACATCTTTGCCTTCGGCTTTCCTGTGCCTCCCTTCCTGCTGGAGCTTGGCTCCCAGGTACACTT
CGCGCTGCGCTATGGCGTGGCTGGTGCCGAGTACTGGGACAACAATGATGGTCAGGACTATAGC
CTTACTTGTCGCAGTCATGCCCTGCACATGCCACGCGGGGAGTGCGAGGAGAGCTGGATCCACT
TCATCTGAACTGCAGGCTGTGAATGTGGAGCTTCCACCTCTGCAGACCTGCAGTCCCTTTCCCA
CCAGTGCAGCTCTCAGAGCCGCCATCTCCCATCCCACCCTTCCTTCCCGGTTTCCTGGCCTCAT
TTCTCACTGTGAAGCCCTGCGGCTGTAGCCTGGCCTGCCCTGTAGTGAATTCTCTGGAGAGCCT
GTCAGGGTCAGAAGACCAGGAGCCTGTGTAATACATTGTGGAGAGGGTGTGGGAGGGCAGATGC
ATGGGATTGTGGTCCTCAACTTCAGGAGGACCCACAGGTCAGTGTTTTGCAAGAAAGGCCTTTT
GCATGTCTCTTCAATGTCTAAACACAAGTATCTGTTATTTATTATTGTGACGTTAGCCTTCCAC
TCATGGTGGACGCTTTCTCAGGAATACTCTAGATTTAATCAGCTTAAAGAAGGCCTGTTGTCTG
TTTGCACCCCCTGTAATGTTTGTAAAGAATACACAGTGTAGCCCACATTATGGTCCCTCGAGGC
ATTTCCACCCTGGGATAGTGAAAACCTGAGACCATGTTTGCTTGCCAGTGTCTGTAGCCTTCTA
ACAGTGGAGACTATTAATAGCGAAGGCACTTAGAGCTCATCTGTCATCACACAACCATTTCTGG
GCTTCGAGGCTGCCCTGGTTAGCCGGTGCCTCCCACATCAACGGCTCGGAAAGAGTGGACTGAA
AAGCTTCCAACTGAGCAACTTAGCCCAGACAGTCCTTTCTCTTCAGGGACTGCCTGTTCACGAG
TTTGTCTTCTACTGGTCTGGTTGTGGGTCTGTGTCTTAGCAGGCCATATTCTGTTTAAGTTTGA
AACTACCTGAGCCTTTAAAAAGATCTTGCCTTAAGTAATTTCCGTTTTCAAGTGGCCACAGGGA
TTCAGGCAGGCGTGCCCATCCCAGAGACCTTTTCCACGAAAGAGGTGACTTTTTAATTTCTAAG
TATGGAAAGGTTCCAGCATCCATATTTTGGAAGCCAGCTTCCAAGTGAACCTGGGTGGTTCTTA
GAATTAGCCAGGGCACTGGAGGAAGAATAATTCACGGATTTTTATACAGCTAACGGGTTTTAAA
TTGAACTGTTATGTCAGGTTTCACAGATGCCGGCCACTTTATTCTTTGTGCCTTTGGTTAGGAA
AGTTGCTAACTTTTTTTTTTACGGGTTTAATTCCTAGTTTTAAGATGTTACATAGTTTAAAAAA
AGAAAACAACCAAAACCTCCAACTTAGTCCAGACCGCTAGCTGACCCCTGCTGTTTAAAGCCCC
CATGGAGAAGCTGGCAAATATTTTTGGTGCTGAGCTTTGGGTCTCTCTGACAGCAGGTGCTAGA
ATTGAGGTGGACAAGACCTCCAAGATGGGACTTTTGCTTTTGAGACAGTGGATGTCCCACAATA
AAACCACCCAGCCTTTGGCTGCTAGGACAACGCACTGCCTTGGCATTCAAGAGTGAGTAGAGCT
CAGTGGCATTTCCCACTGCTTAATGAGATGTTCAATTAGGTCAGCGAACCCCGGAGGGTCATGG
CAACTCTGTCCCTGGCCCCTGTCCAGAGTGCAAGAGAATGGGCCAGACTCAAGTCAAAGTCAGG
AGCACCGATGCTCGAGAGTTCGTAGAGAGTTTTACAGTCCATGGGAACGCCTCTCGCTTGTCCG
CAGGTTCTGGTTACAGAAAAGTAAAGGACGCATTATCAAAATCAAGAGAACCTGAAGGTGCCTT
TTAAGACATACCAACCATTTGAAATCTAAAACACAGAGATAATTCTGCTTGATTAAACAAGTAC
ATAGTAAATAAAAGCTGTAAAGATAATTCAGGGTGAACTTTCTGACCCCGAGACACATTTAGGA
CTGTTGGGATGTTAAAATTGTGTCGACTGTGCACTCACTGAGTTGTGTTTTACTGCCTGTCATT
TAAAGTCATTTTACTCAAGCCTGAATATTAAAGAACACGTGTGAAAAAACAAAAGTCCCTTTGT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001103034	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL88854	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000068843
	ENSRNOP00000068843.1
	ENSRNOP00000072427.2
	ENSRNOP00000101831.1

RefSeq Acc Id:

NP_001103034 ⟸ NM_001109564

- UniProtKB:

D3ZZ26 (UniProtKB/TrEMBL), A6KME6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSKGPDSALLPSTPGPRKLAPRSLSCLSDMDGRSCRPPGCDPRLRPIIQRRSRSLPTSPERRAK
AAGAQGAACGAGCNRQVRVRFADALGLELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQDL
EFTLQCLVPDFQPPIEVPGFGDRLARQLVCLERVTCSDLGISGTVRVRNVAFEKQVTVRYTFSG
WRSAHEAVARWRGPAGGEGTEDIFAFGFPVPPFLLELGSQVHFALRYGVAGAEYWDNNDGQDYS
LTCRSHALHMPRGECEESWIHFI

hide sequence

Ensembl Acc Id:

ENSRNOP00000068843 ⟸ ENSRNOT00000090468

Ensembl Acc Id:

ENSRNOP00000101831 ⟸ ENSRNOT00000170588

Ensembl Acc Id:

ENSRNOP00000072427 ⟸ ENSRNOT00000091212

Protein Domains

CBM21

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZZ26-F1-model_v2	AlphaFold	D3ZZ26	1-279	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1586306	AgrOrtholog
BioCyc Gene	G2FUF-46399	BioCyc
Ensembl Genes	ENSRNOG00000053869	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000090468	ENTREZGENE
	ENSRNOT00000090468.3	UniProtKB/TrEMBL
	ENSRNOT00000091212.3	UniProtKB/TrEMBL
	ENSRNOT00000170588.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.2440	UniProtKB/TrEMBL
InterPro	CBM21_dom_sf	UniProtKB/TrEMBL
	CBM_21	UniProtKB/TrEMBL
	FAM217	UniProtKB/TrEMBL
	Pase-1_Glycogen_target-su_met	UniProtKB/TrEMBL
	PP1_regulatory_subunit_3	UniProtKB/TrEMBL
KEGG Report	rno:689995	UniProtKB/TrEMBL
NCBI Gene	689995	ENTREZGENE
PANTHER	PROTEIN FAM217B	UniProtKB/TrEMBL
	PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT	UniProtKB/TrEMBL
	PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3D	UniProtKB/TrEMBL
	SI:CH211-266K22.6	UniProtKB/TrEMBL
Pfam	CBM_21	UniProtKB/TrEMBL
	FAM217	UniProtKB/TrEMBL
PhenoGen	Ppp1r3d	PhenoGen
PIRSF	PP1_GT_animal	UniProtKB/TrEMBL
PROSITE	CBM21	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000053869	RatGTEx
UniProt	A6KME6	ENTREZGENE, UniProtKB/TrEMBL
	D3ZZ26	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A0G2K2Y5	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Ppp1r3d	protein phosphatase 1, regulatory subunit 3D	LOC689995	similar to Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1, regulatory subunit 6) (Protein phosphatase 1-binding subunit R6)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC689995	similar to Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1, regulatory subunit 6) (Protein phosphatase 1-binding subunit R6)	LOC682185	similar to Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1, regulatory subunit 6) (Protein phosphatase 1-binding subunit R6)	Data merged from RGD:1586905	1643240	APPROVED
2006-11-19	LOC689995	similar to Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1, regulatory subunit 6) (Protein phosphatase 1-binding subunit R6)			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-19	LOC682185	similar to Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1, regulatory subunit 6) (Protein phosphatase 1-binding subunit R6)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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RGD Manual Annotations

Imported Annotations - KEGG (archival)