Mterf3 (mitochondrial transcription termination factor 3)

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Gene: Mterf3 (mitochondrial transcription termination factor 3) Rattus norvegicus

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Symbol:

Mterf3

Name:

mitochondrial transcription termination factor 3

RGD ID:

735158

Description:

Predicted to enable transcription cis-regulatory region binding activity. Predicted to be involved in mitochondrial ribosome assembly; mitochondrial transcription; and negative regulation of DNA-templated transcription. Predicted to be located in cytosol. Predicted to be active in mitochondrion. Orthologous to human MTERF3 (mitochondrial transcription termination factor 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

CGI-12 protein; Cgi12; MGC72611; MTERF domain containing 1; mTERF domain-containing protein 1, mitochondrial; Mterfd1; similar to RIKEN cDNA 2410017I18; transcription termination factor 3, mitochondrial

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	65,711,654 - 65,729,926 (-)	NCBI		GRCr8
mRatBN7.2	7	63,826,418 - 63,844,747 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	63,826,427 - 63,844,658 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	65,715,625 - 65,733,862 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	67,917,913 - 67,936,045 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	67,710,575 - 67,728,810 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	71,275,544 - 71,293,842 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	71,273,275 - 71,293,823 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	71,447,410 - 71,465,707 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	67,969,806 - 67,988,047 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	67,990,538 - 68,008,777 (-)	NCBI
Celera	7	60,959,013 - 60,977,102 (-)	NCBI		Celera
Cytogenetic Map	7	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Klippel-Feil syndrome 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2-methylcholine (ISO)

3-chloropropane-1,2-diol (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (ISO)

Aroclor 1254 (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

C60 fullerene (EXP)

cadmium dichloride (EXP)

chloroquine (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cycloheximide (ISO)

cyclosporin A (ISO)

DDE (ISO)

diarsenic trioxide (ISO)

diazinon (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

dimethyl fumarate (ISO)

diuron (ISO)

doxorubicin (ISO)

flutamide (EXP)

formaldehyde (ISO)

indole-3-methanol (EXP)

lipopolysaccharide (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-methyl-4-phenylpyridinium (ISO)

nefazodone (EXP)

ochratoxin A (ISO)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

phenobarbital (ISO)

potassium chromate (ISO)

quercetin (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mitochondrial ribosome assembly (IBA)

mitochondrial transcription (IBA)

negative regulation of DNA-templated transcription (ISO,ISS)

Cellular Component

cytosol (ISO)

mitochondrial matrix (ISO)

mitochondrion (IBA,ISO,ISS)

Molecular Function

protein binding (ISO)

transcription cis-regulatory region binding (ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:17662942	PMID:18614015

Genomics

Comparative Map Data

Mterf3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	65,711,654 - 65,729,926 (-)	NCBI		GRCr8
mRatBN7.2	7	63,826,418 - 63,844,747 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	63,826,427 - 63,844,658 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	65,715,625 - 65,733,862 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	67,917,913 - 67,936,045 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	67,710,575 - 67,728,810 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	71,275,544 - 71,293,842 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	71,273,275 - 71,293,823 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	71,447,410 - 71,465,707 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	67,969,806 - 67,988,047 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	67,990,538 - 68,008,777 (-)	NCBI
Celera	7	60,959,013 - 60,977,102 (-)	NCBI		Celera
Cytogenetic Map	7	q22	NCBI

MTERF3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	96,239,398 - 96,261,613 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	96,239,398 - 96,261,610 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	97,251,626 - 97,273,841 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	97,320,821 - 97,342,972 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	93,437,637 - 93,459,789 (-)	NCBI		Celera
Cytogenetic Map	8	q22.1	NCBI
HuRef	8	92,457,196 - 92,479,318 (-)	NCBI		HuRef
CHM1_1	8	97,291,884 - 97,314,036 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	97,364,733 - 97,387,331 (-)	NCBI		T2T-CHM13v2.0

Mterf3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	67,053,520 - 67,081,148 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	67,055,032 - 67,081,152 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	66,906,577 - 66,933,083 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	66,906,968 - 66,933,088 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	67,013,031 - 67,034,008 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	67,347,875 - 67,368,816 (-)	NCBI		MGSCv36	mm8
Celera	13	70,371,705 - 70,392,691 (+)	NCBI		Celera
Cytogenetic Map	13	B3	NCBI
cM Map	13	34.54	NCBI

Mterf3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955417	12,235,490 - 12,269,261 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955417	12,232,897 - 12,268,572 (-)	NCBI	ChiLan1.0	ChiLan1.0

MTERF3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	113,571,849 - 113,594,083 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	89,110,771 - 89,132,986 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	92,864,512 - 92,886,757 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	95,062,088 - 95,084,035 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	95,062,088 - 95,084,035 (-)	Ensembl	panpan1.1		panPan2

MTERF3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	29	40,750,863 - 40,772,111 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	29	40,750,909 - 40,768,956 (-)	NCBI	CanFam3.1		canFam3	CanFam3.1
CanFam3.1 Ensembl	29	40,750,909 - 40,768,956 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	29	40,942,583 - 40,963,883 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	29	40,940,419 - 40,960,049 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	29	40,985,409 - 41,006,682 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	29	40,954,494 - 40,975,700 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	29	41,417,269 - 41,438,499 (-)	NCBI		UU_Cfam_GSD_1.0

Mterf3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	38,849,499 - 38,870,372 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	46,275,587 - 46,296,456 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	46,275,587 - 46,296,456 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MTERF3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	40,376,187 - 40,399,609 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	40,376,146 - 40,399,614 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	43,554,874 - 43,578,509 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MTERF3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	91,203,095 - 91,223,524 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	91,203,169 - 91,223,512 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	49,560,948 - 49,584,538 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mterf3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624763	3,556,483 - 3,587,318 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624763	3,558,707 - 3,587,546 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mterf3
70 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	36
Count of miRNA genes:	35
Interacting mature miRNAs:	35
Transcripts:	ENSRNOT00000006185
Prediction methods:	Microtar, Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411569	Bw137	Body weight QTL 137		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	21921195	66921195	Rat
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
2293667	Bss42	Bone structure and strength QTL 42	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	7	47651439	92651439	Rat
10053722	Scort27	Serum corticosterone level QTL 27	2.41	0.0083	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	43228750	88228750	Rat
1641885	Alcrsp9	Alcohol response QTL 9			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	7	24099606	69099606	Rat
1549840	Bss5	Bone structure and strength QTL 5	9.8		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	24751841	69751841	Rat
2317035	Aia16	Adjuvant induced arthritis QTL 16	2.71		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	59238038	104238038	Rat
1300127	Srn1	Serum renin concentration QTL 1	3.87		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	7	29409683	84928080	Rat
10059605	Kidm47	Kidney mass QTL 47	2.91	0.05	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	47251783	65728867	Rat
2293678	Bss24	Bone structure and strength QTL 24	6.71	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	7	47651439	92651439	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	43747012	108555253	Rat
631513	Scl7	Serum cholesterol level QTL 7	4.1		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	37960569	82960569	Rat
2293685	Bmd21	Bone mineral density QTL 21	4.2	0.0003	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	7	47651439	92651439	Rat
10755453	Coatc12	Coat color QTL 12		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	31112832	76112832	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	44421311	118198041	Rat
634326	Hc3	Hypercalciuria QTL 3	2.1		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	7	42787314	87787314	Rat
2293696	Bmd32	Bone mineral density QTL 32	5.1	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	7	47651439	92651439	Rat
7411605	Foco14	Food consumption QTL 14	24.1	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	34293282	79293282	Rat
1300151	Bp181	Blood pressure QTL 181	3.36		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	7	53612714	103945643	Rat
1559283	Emca4	Estrogen-induced mammary cancer QTL 4	3.7		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	7	62004452	101773158	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	9462246	98011544	Rat
738030	Anxrr8	Anxiety related response QTL 8	4.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	46590070	91590070	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	43747099	102228765	Rat
631534	Lnnr1	Liver neoplastic nodule remodeling QTL 1	3.85	0.001	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	7	34293282	79293282	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
2293707	Bss32	Bone structure and strength QTL 32	7.64	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	47651439	92651439	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	41333674	119109060	Rat
2293644	Bmd29	Bone mineral density QTL 29	5.4	0.0001	femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	7	47651439	92651439	Rat
70190	Mcs6	Mammary carcinoma susceptibility QTL 6	2.29		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	7	26737401	63902784	Rat
2300178	Bmd54	Bone mineral density QTL 54	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	7	47651439	92651439	Rat
1298528	Bp169	Blood pressure QTL 169		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	61074194	106074194	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	44867533	89867533	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	19654317	84928080	Rat
1576303	Ept7	Estrogen-induced pituitary tumorigenesis QTL 7	3.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	7	62004452	101773158	Rat
10402855	Bp379	Blood pressure QTL 379		0.21	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	29409683	74409683	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_199387	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241509	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC062080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006185 ⟹ ENSRNOP00000006185

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	63,826,427 - 63,844,658 (-)	Ensembl
Rnor_6.0 Ensembl	7	71,273,275 - 71,293,823 (-)	Ensembl

RefSeq Acc Id:

NM_199387 ⟹ NP_955419

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	65,711,654 - 65,729,895 (-)	NCBI
mRatBN7.2	7	63,826,418 - 63,844,662 (-)	NCBI
Rnor_6.0	7	71,275,544 - 71,293,785 (-)	NCBI
Rnor_5.0	7	71,447,410 - 71,465,707 (-)	NCBI
RGSC_v3.4	7	67,969,806 - 67,988,047 (-)	RGD
Celera	7	60,959,013 - 60,977,102 (-)	RGD

Sequence:

show sequence

CCGGCGTGGGTTGCGCGGTCGCTGGGAAGAAGGAGCGCGAAGCTGCGGCCGGGCTGGGTTAGGG
TCCGGCCTACCTGTACCCAGCAGGATCCGGGAGCCTCGCGGCTTGACTAAAATGTCAGAAAAAA
CATGGCCTTGTTAGCCCAACAGTTATCCAGATGGTTCAACTCAGTTAAATTGAGTAGCTTCATT
AAAGCCACACAAGTCACAAAACACTCTGCAGGACTAGGAAAAAATGCCTCAGCTCAGGCCCTGT
TGTCCTCTGACACCTGCTTTCTCCAGTGGGGAATTAAGACTGACAGGGCTTTGTTCTCCTGGAG
CAGTTTCCAGTCGGCCAACACAACTAGAAGAAAGAGTTCTACCAACAGCACTCTGCTTCCTTCA
GTGAGTGAACAGCCAGAGAAGATACCTAGGCTTGAATCTGAGCTGCCTCTGGAAGAACTGGACG
ACTTGCCTCCGCTGTCTCCGTTACAGCCAGTTTCAGAGGAGGAGGCTATTCAGATTGCTGCATA
CTCCCCGCTGCCCCTTTCCTCCTCCACACTTGCAGATTACGTAGACCATTCCGAGACTCTACAG
AAGCTGGTGCAGCTTGGAGTAGATTTGTCTAAGATAGAAAAACATCCAGATGTAGCCAACCTCC
TTCTAAGACTGAATTTTGAAAAAGACATTAAGCAAATACTGCTATTTCTTAAAGATTTGGGTTT
AGAAGATAACCAACTGGGACCATTTCTGACAAAAAATTATGCTATTTTCTCTGAAGACCTTGAA
AATCTTAAGACCAGAGTAGCTTATCTACAGTCAAAAAATTTCAGTAAGACAGATATTGCCTGTA
TGGTCAAAAATGCACCATTTCTGTTGAGCTTCTCCGTGGAAAGACTAGATAACAGACTGGGATT
TTTTCAGAAAGAACTGGAACTGAGTGTGAAGAAGACTAGAGATCTGGTTGTTCGTCTTCCAAGG
CTACTAACAGGAAGTCTGGAGCCTGTGAAGGAAAACATGAAGGTTTACCGCCTTGAACTTGGTT
TTAAACATAATGAAATTCAGCATATGGTCACCAAGATCCCTAAGATGCTAACTGCAAACAAAAG
AAAACTTACGGAGACTTTTGATTATGTACACAATGTGATGAATATTCCCCACCATATCATTGTC
AAGTTCCCACAGGTATTTAATACAAGAGTATTTAAAATTAAAGAAAGACACTTGTTTCTTGCCT
ACTTGGGCAAAGCACAGTATGATCCAGCAAAACCTAACTATGTGTCTTTGGACAAGTTCGTATC
TTTTCCTGATGAAGTATTTTGTAAAGAGATTGCCAAAGCTTCAGTAAACGATTTTGAGAAATTC
TTAAAAACTCTTTAGTTTTTGATGAATGTTTAAATATATTCTTGTAAATATATACATGAATAAA
CTTATTTTTAAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006241509 ⟹ XP_006241571

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	65,711,654 - 65,729,926 (-)	NCBI
mRatBN7.2	7	63,826,418 - 63,844,747 (-)	NCBI
Rnor_6.0	7	71,275,544 - 71,293,842 (-)	NCBI
Rnor_5.0	7	71,447,410 - 71,465,707 (-)	NCBI

Sequence:

show sequence

GCGGCGCCGGCTGAGCGTGGCGAATCGCTGTCTTGCTGAGCGACAGTGCGCTGGACCCCGGCGT
GGGTTGCGCGGTCGCTGGGAAGAAGGAGCGCGAAGCTGCGGCCGGGCTGGGTTAGGGTCCGGCC
TACCTGTACCCAGCAGGATCCGGGAGCCTCGCGGCTTGACTAAAATGTCAGAAAAAACATGGCC
TTGTTAGCCCAACAGTTATCCAGATGGTTCAACTCAGTTAAATTGAGTAGCTTCATTAAAGCCA
CACAAGTCACAAAACACTCTGCAGGACTAGGAAAAAATGCCTCAGCTCAGGCCCTGTTGTCCTC
TGACACCTGCTTTCTCCAGTGGGGAATTAAGACTGACAGGGCTTTGTTCTCCTGGAGCAGTTTC
CAGTCGGCCAACACAACTAGAAGAAAGAGTTCTACCAACAGCACTCTGCTTCCTTCAGTGAGTG
AACAGCCAGAGAAGATACCTAGGCTTGAATCTGAGCTGCCTCTGGAAGAACTGGACGACTTGCC
TCCGCTGTCTCCGTTACAGCCAGTTTCAGAGGAGGAGGCTATTCAGATTGCTGCATACTCCCCG
CTGCCCCTTTCCTCCTCCACACTTGCAGATTACGTAGACCATTCCGAGACTCTACAGAAGCTGG
TGCAGCTTGGAGTAGATTTGTCTAAGATAGAAAAACATCCAGATGTAGCCAACCTCCTTCTAAG
ACTGAATTTTGAAAAAGACATTAAGCAAATACTGCTATTTCTTAAAGATTTGGGTTTAGAAGAT
AACCAACTGGGACCATTTCTGACAAAAAATTATGCTATTTTCTCTGAAGACCTTGAAAATCTTA
AGACCAGAGTAGCTTATCTACAGTCAAAAAATTTCAGTAAGACAGATATTGCCTGTATGGTCAA
AAATGCACCATTTCTGTTGAGCTTCTCCGTGGAAAGACTAGATAACAGACTGGGATTTTTTCAG
AAAGAACTGGAACTGAGTGTGAAGAAGACTAGAGATCTGGTTGTTCGTCTTCCAAGGCTACTAA
CAGGAAGTCTGGAGCCTGTGAAGGAAAACATGAAGGTATTTAATACAAGAGTATTTAAAATTAA
AGAAAGACACTTGTTTCTTGCCTACTTGGGCAAAGCACAGTATGATCCAGCAAAACCTAACTAT
GTGTCTTTGGACAAGTTCGTATCTTTTCCTGATGAAGTATTTTGTAAAGAGATTGCCAAAGCTT
CAGTAAACGATTTTGAGAAATTCTTAAAAACTCTTTAGTTTTTGATGAATGTTTAAATATATTC
TTGTAAATATATACATGAATAAACTTATTTTTAAAATAAA

hide sequence

RefSeq Acc Id:

XM_039078623 ⟹ XP_038934551

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	65,711,654 - 65,724,148 (-)	NCBI
mRatBN7.2	7	63,826,418 - 63,844,744 (-)	NCBI

RefSeq Acc Id:

XM_063263148 ⟹ XP_063119218

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	65,711,654 - 65,724,148 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_955419	(Get FASTA)	NCBI Sequence Viewer
	XP_006241571	(Get FASTA)	NCBI Sequence Viewer
	XP_038934551	(Get FASTA)	NCBI Sequence Viewer
	XP_063119218	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH62080	(Get FASTA)	NCBI Sequence Viewer
	EDM16440	(Get FASTA)	NCBI Sequence Viewer
	EDM16441	(Get FASTA)	NCBI Sequence Viewer
	EDM16442	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006185.5
	ENSRNOP00055037356
	ENSRNOP00060011278
	ENSRNOP00065022028
GenBank Protein	Q6P6Q6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_955419 ⟸ NM_199387
- Peptide Label:	precursor
- UniProtKB:	Q6P6Q6 (UniProtKB/Swiss-Prot), A6HQY0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALLAQQLSRWFNSVKLSSFIKATQVTKHSAGLGKNASAQALLSSDTCFLQWGIKTDRALFSWS SFQSANTTRRKSSTNSTLLPSVSEQPEKIPRLESELPLEELDDLPPLSPLQPVSEEEAIQIAAY SPLPLSSSTLADYVDHSETLQKLVQLGVDLSKIEKHPDVANLLLRLNFEKDIKQILLFLKDLGL EDNQLGPFLTKNYAIFSEDLENLKTRVAYLQSKNFSKTDIACMVKNAPFLLSFSVERLDNRLGF FQKELELSVKKTRDLVVRLPRLLTGSLEPVKENMKVYRLELGFKHNEIQHMVTKIPKMLTANKR KLTETFDYVHNVMNIPHHIIVKFPQVFNTRVFKIKERHLFLAYLGKAQYDPAKPNYVSLDKFVS FPDEVFCKEIAKASVNDFEKFLKTL hide sequence

RefSeq Acc Id:

XP_006241571 ⟸ XM_006241509

- Peptide Label:

isoform X1

- Sequence:

show sequence

MALLAQQLSRWFNSVKLSSFIKATQVTKHSAGLGKNASAQALLSSDTCFLQWGIKTDRALFSWS
SFQSANTTRRKSSTNSTLLPSVSEQPEKIPRLESELPLEELDDLPPLSPLQPVSEEEAIQIAAY
SPLPLSSSTLADYVDHSETLQKLVQLGVDLSKIEKHPDVANLLLRLNFEKDIKQILLFLKDLGL
EDNQLGPFLTKNYAIFSEDLENLKTRVAYLQSKNFSKTDIACMVKNAPFLLSFSVERLDNRLGF
FQKELELSVKKTRDLVVRLPRLLTGSLEPVKENMKVFNTRVFKIKERHLFLAYLGKAQYDPAKP
NYVSLDKFVSFPDEVFCKEIAKASVNDFEKFLKTL

hide sequence

Ensembl Acc Id:

ENSRNOP00000006185 ⟸ ENSRNOT00000006185

RefSeq Acc Id:	XP_038934551 ⟸ XM_039078623
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063119218 ⟸ XM_063263148
- Peptide Label:	isoform X3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6P6Q6-F1-model_v2	AlphaFold	Q6P6Q6	1-409	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695274

Promoter ID:

EPDNEW_R5799

Type:

initiation region

Name:

Mterf3_1

Description:

mitochondrial transcription termination factor 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	71,293,798 - 71,293,858	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:735158	AgrOrtholog
BioCyc Gene	G2FUF-33710	BioCyc
Ensembl Genes	ENSRNOG00000004492	Ensembl, UniProtKB/Swiss-Prot
	ENSRNOG00055026432	UniProtKB/Swiss-Prot
	ENSRNOG00060008748	UniProtKB/Swiss-Prot
	ENSRNOG00065016732	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000006185.7	UniProtKB/Swiss-Prot
	ENSRNOT00055045592	UniProtKB/Swiss-Prot
	ENSRNOT00060014623	UniProtKB/Swiss-Prot
	ENSRNOT00065027909	UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.70.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5599618	IMAGE-MGC_LOAD
InterPro	MTERF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MTERF_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:299514	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:72611	IMAGE-MGC_LOAD
NCBI Gene	299514	ENTREZGENE
PANTHER	CGI-12 PROTEIN-RELATED	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
	TRANSCRIPTION TERMINATION FACTOR 3, MITOCHONDRIAL	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	mTERF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Mterf3	PhenoGen
RatGTEx	ENSRNOG00000004492	RatGTEx
	ENSRNOG00055026432	RatGTEx
	ENSRNOG00060008748	RatGTEx
	ENSRNOG00065016732	RatGTEx
SMART	Mterf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A6HQY0	ENTREZGENE, UniProtKB/TrEMBL
	MTEF3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-10	Mterf3	mitochondrial transcription termination factor 3	Mterfd1	MTERF domain containing 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Mterfd1	MTERF domain containing 1	Cgi12	CGI-12 protein	Symbol and Name updated	1299863	APPROVED
2005-07-08	Cgi12	CGI-12 protein	MGC72611	similar to RIKEN cDNA 2410017I18	Symbol and Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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