Alpk2 (alpha-kinase 2) - Rat Genome Database

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Gene: Alpk2 (alpha-kinase 2) Rattus norvegicus
Analyze
Symbol: Alpk2
Name: alpha-kinase 2
RGD ID: 1564431
Description: Predicted to be involved in several processes, including epicardium morphogenesis; heart development; and negative regulation of Wnt signaling pathway involved in heart development. Predicted to act upstream of or within regulation of gene expression. Predicted to be located in basolateral plasma membrane. Orthologous to human ALPK2 (alpha kinase 2); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding (Ensembl: pseudogene)
RefSeq Status: VALIDATED
Previously known as: alpha-protein kinase 2; LOC498875; RGD1564431; similar to heart alpha-kinase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Bp319
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81861,045,717 - 61,161,703 (-)NCBIGRCr8
mRatBN7.21858,775,603 - 58,906,150 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1858,775,605 - 58,906,258 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01860,960,009 - 61,072,116 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1860,960,662 - 61,057,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01860,158,973 - 60,268,224 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41861,562,696 - 61,587,804 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1856,922,773 - 57,035,140 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP)
calcitriol  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt atom  (ISO)
copper(II) sulfate  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
enzalutamide  (ISO)
fenofibrate  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
isoprenaline  (ISO)
levonorgestrel  (ISO)
mercury dibromide  (ISO)
methylmercury chloride  (ISO)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
testosterone undecanoate  (ISO)
triadimefon  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
Tungsten carbide  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vincristine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:22641666   PMID:28668886   PMID:29888752  


Genomics

Comparative Map Data
Alpk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81861,045,717 - 61,161,703 (-)NCBIGRCr8
mRatBN7.21858,775,603 - 58,906,150 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1858,775,605 - 58,906,258 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01860,960,009 - 61,072,116 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1860,960,662 - 61,057,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01860,158,973 - 60,268,224 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41861,562,696 - 61,587,804 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1856,922,773 - 57,035,140 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
ALPK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381858,481,247 - 58,629,091 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1858,481,247 - 58,629,091 (-)EnsemblGRCh38hg38GRCh38
GRCh371856,148,479 - 56,296,323 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361854,299,459 - 54,447,169 (-)NCBINCBI36Build 36hg18NCBI36
Build 341854,299,463 - 54,398,381NCBI
Celera1852,864,790 - 53,011,746 (-)NCBICelera
Cytogenetic Map18q21.31-q21.32NCBI
HuRef1852,856,619 - 53,004,353 (-)NCBIHuRef
CHM1_11856,143,681 - 56,291,408 (-)NCBICHM1_1
T2T-CHM13v2.01858,681,900 - 58,830,246 (-)NCBIT2T-CHM13v2.0
Alpk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391865,398,600 - 65,526,959 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1865,398,600 - 65,527,137 (-)EnsemblGRCm39 Ensembl
GRCm381865,265,529 - 65,393,888 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1865,265,529 - 65,394,066 (-)EnsemblGRCm38mm10GRCm38
MGSCv371865,425,183 - 65,553,542 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361865,391,194 - 65,474,903 (-)NCBIMGSCv36mm8
Celera1866,541,032 - 66,666,987 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1838.41NCBI
Alpk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540242,749,534 - 42,871,772 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540242,749,005 - 42,871,756 (-)NCBIChiLan1.0ChiLan1.0
ALPK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21776,022,313 - 76,153,298 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11861,714,926 - 61,846,177 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01851,872,394 - 52,020,137 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11855,205,337 - 55,352,100 (-)NCBIpanpan1.1PanPan1.1panPan2
ALPK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1117,421,673 - 17,563,732 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl117,445,543 - 17,583,600 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha118,428,963 - 18,547,640 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0117,301,628 - 17,443,969 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl117,326,519 - 17,446,007 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1117,360,210 - 17,502,294 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0117,258,137 - 17,400,351 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0117,526,061 - 17,668,450 (+)NCBIUU_Cfam_GSD_1.0
Alpk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494430,710,592 - 30,810,043 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364975,949,640 - 6,048,425 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364975,934,857 - 6,049,090 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALPK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1162,175,573 - 162,305,305 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11162,175,241 - 162,308,074 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21179,761,531 - 179,891,873 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALPK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11821,123,913 - 21,252,228 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1821,107,369 - 21,252,693 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660604,318,054 - 4,446,186 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Alpk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247923,966,683 - 4,111,504 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247923,967,876 - 4,148,169 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:99
Count of miRNA genes:86
Interacting mature miRNAs:93
Transcripts:ENSRNOT00000042352
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)182201556261600538Rat
1331730Scl27Serum cholesterol level QTL 273.826blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)185449080186134022Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
1300125Rf26Renal function QTL 263.2urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)185335052168120379Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)183857591983575919Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182682218671822186Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182682218671822186Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182682218671822186Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184562030686134022Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050563968306Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182682218671822186Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184891573786134022Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184891573786134022Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182682218671822186Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182682218671822186Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)185384517561982387Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183199089176990891Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184562030686134022Rat
61360EaeyExperimental allergic encephalomyelitis QTL y3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)184918722662647720Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183161050585493247Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)183337915878379158Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)184046238385462383Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185449080176272247Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)183199089176990891Rat
1331752Bw27Body weight QTL 272.963body mass (VT:0001259)body weight (CMO:0000012)185449080168120379Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)183337915878379158Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)183337915878379158Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)183337915878379158Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)185079521286134022Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182682218671822186Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183152278376522783Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)183337915878379158Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183337915878379158Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)183337915878379158Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185782524385493247Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183161050577371277Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183612162681121626Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)183199089176990891Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184891573786134022Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)182641582171415821Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183164450879484311Rat
1598832Glom11Glomerulus QTL 112.9kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)185326667186134022Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)183199089176990891Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)185079521286134022Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183161050572538878Rat
7411719Strs5Sensitivity to stroke QTL 59.4cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)185219805968120379Rat

Markers in Region
D18Rat61  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81861,075,796 - 61,076,043 (+)Marker Load Pipeline
mRatBN7.21858,805,687 - 58,805,936 (+)MAPPERmRatBN7.2
Rnor_6.01860,971,508 - 60,971,754NCBIRnor6.0
Rnor_5.01860,167,906 - 60,168,152UniSTSRnor5.0
RGSC_v3.41861,571,526 - 61,571,773RGDRGSC3.4
RGSC_v3.41861,571,527 - 61,571,773UniSTSRGSC3.4
RGSC_v3.11861,644,728 - 61,644,974RGD
Celera1856,934,591 - 56,934,837UniSTS
RH 3.4 Map18595.5RGD
RH 3.4 Map18595.5UniSTS
RH 2.0 Map18321.4RGD
SHRSP x BN Map1833.1899RGD
FHH x ACI Map1843.03RGD
Cytogenetic Map18q12.1UniSTS
RH134129  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21858,775,744 - 58,775,939 (+)MAPPERmRatBN7.2
Rnor_6.01860,772,287 - 60,772,481NCBIRnor6.0
Rnor_5.01859,973,813 - 59,974,007UniSTSRnor5.0
RGSC_v3.41861,529,789 - 61,529,983UniSTSRGSC3.4
Celera1856,906,511 - 56,906,705UniSTS
RH 3.4 Map18571.8UniSTS
Cytogenetic Map18q12.1UniSTS
AU049015  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81861,085,291 - 61,085,535 (+)Marker Load Pipeline
mRatBN7.21858,815,197 - 58,815,442 (+)MAPPERmRatBN7.2
Rnor_6.01860,981,003 - 60,981,246NCBIRnor6.0
Rnor_5.01860,177,401 - 60,177,644UniSTSRnor5.0
RGSC_v3.41861,581,022 - 61,581,265UniSTSRGSC3.4
Celera1856,944,070 - 56,944,314UniSTS
Cytogenetic Map18q12.1UniSTS
STS-X52486  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21858,846,726 - 58,848,115 (+)MAPPERmRatBN7.2
Rnor_6.01861,012,598 - 61,013,986NCBIRnor6.0
Rnor_5.01860,208,996 - 60,210,384UniSTSRnor5.0
RGSC_v3.41861,612,542 - 61,613,930UniSTSRGSC3.4
Celera1856,975,516 - 56,976,886UniSTS
Cytogenetic Map18q12.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 87 86 55 25 55 6 214 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000042352   ⟹   ENSRNOP00000043873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1858,775,605 - 58,906,258 (-)Ensembl
Rnor_6.0 Ensembl1860,960,662 - 61,057,365 (-)Ensembl
RefSeq Acc Id: XM_039097413   ⟹   XP_038953341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81861,045,717 - 61,161,703 (-)NCBI
mRatBN7.21858,775,603 - 58,906,150 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001419400 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953341 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM14682 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000043873   ⟸   ENSRNOT00000042352
RefSeq Acc Id: XP_038953341   ⟸   XM_039097413

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LTG2-F1-model_v2 AlphaFold F1LTG2 1-2040 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564431 AgrOrtholog
BioCyc Gene G2FUF-7229 BioCyc
Ensembl Genes ENSRNOG00000017421 Ensembl
NCBI Gene 498875 ENTREZGENE
PhenoGen Alpk2 PhenoGen
RatGTEx ENSRNOG00000017421 RatGTEx


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Alpk2  alpha-kinase 2  RGD1564431_predicted  similar to heart alpha-kinase (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564431_predicted  similar to heart alpha-kinase (predicted)  LOC498875  similar to heart alpha-kinase  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498875  similar to heart alpha-kinase      Symbol and Name status set to provisional 70820 PROVISIONAL