Alpk2 (alpha kinase 2) - Rat Genome Database

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Gene: Alpk2 (alpha kinase 2) Chinchilla lanigera
Analyze
Symbol: Alpk2
Name: alpha kinase 2
RGD ID: 8835364
Description: INVOLVED IN cardiac muscle cell development (ortholog); epicardium morphogenesis (ortholog); establishment of cell polarity (ortholog); ASSOCIATED WITH immunodeficiency 12 (ortholog); isolated microphthalmia 3 (ortholog); FOUND IN basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alpha-kinase 2; alpha-protein kinase 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540242,749,534 - 42,871,772 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540242,749,005 - 42,871,756 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Alpk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540242,749,534 - 42,871,772 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540242,749,005 - 42,871,756 (-)NCBIChiLan1.0ChiLan1.0
ALPK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381858,481,247 - 58,629,091 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1858,481,247 - 58,629,091 (-)EnsemblGRCh38hg38GRCh38
GRCh371856,148,479 - 56,296,323 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361854,299,459 - 54,447,169 (-)NCBINCBI36Build 36hg18NCBI36
Build 341854,299,463 - 54,398,381NCBI
Celera1852,864,790 - 53,011,746 (-)NCBICelera
Cytogenetic Map18q21.31-q21.32NCBI
HuRef1852,856,619 - 53,004,353 (-)NCBIHuRef
CHM1_11856,143,681 - 56,291,408 (-)NCBICHM1_1
T2T-CHM13v2.01858,681,900 - 58,830,246 (-)NCBIT2T-CHM13v2.0
Alpk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391865,398,600 - 65,526,959 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1865,398,600 - 65,527,137 (-)EnsemblGRCm39 Ensembl
GRCm381865,265,529 - 65,393,888 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1865,265,529 - 65,394,066 (-)EnsemblGRCm38mm10GRCm38
MGSCv371865,425,183 - 65,553,542 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361865,391,194 - 65,474,903 (-)NCBIMGSCv36mm8
Celera1866,541,032 - 66,666,987 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1838.41NCBI
Alpk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81861,045,717 - 61,161,703 (-)NCBIGRCr8
mRatBN7.21858,775,603 - 58,906,150 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1858,775,605 - 58,906,258 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01860,960,009 - 61,072,116 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1860,960,662 - 61,057,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01860,158,973 - 60,268,224 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41861,562,696 - 61,587,804 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1856,922,773 - 57,035,140 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
ALPK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21776,022,313 - 76,153,298 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11861,714,926 - 61,846,177 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01851,872,394 - 52,020,137 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11855,205,337 - 55,352,100 (-)NCBIpanpan1.1PanPan1.1panPan2
ALPK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1117,421,673 - 17,563,732 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl117,445,543 - 17,583,600 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha118,428,963 - 18,547,640 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0117,301,628 - 17,443,969 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl117,326,519 - 17,446,007 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1117,360,210 - 17,502,294 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0117,258,137 - 17,400,351 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0117,526,061 - 17,668,450 (+)NCBIUU_Cfam_GSD_1.0
Alpk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494430,710,592 - 30,810,043 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364975,949,640 - 6,048,425 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364975,934,857 - 6,049,090 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALPK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1162,175,573 - 162,305,305 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11162,175,241 - 162,308,074 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21179,761,531 - 179,891,873 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALPK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11821,123,913 - 21,252,228 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1821,107,369 - 21,252,693 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660604,318,054 - 4,446,186 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Alpk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247923,966,683 - 4,111,504 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247923,967,876 - 4,148,169 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000010646   ⟹   ENSCLAP00000010515
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540242,749,534 - 42,871,772 (-)Ensembl
RefSeq Acc Id: XM_005372989   ⟹   XP_005373046
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540242,749,005 - 42,871,755 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013511022   ⟹   XP_013366476
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540242,749,652 - 42,871,756 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013511023   ⟹   XP_013366477
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540242,749,005 - 42,859,487 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005373046 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366476 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366477 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000010515
  ENSCLAP00000010515.1
RefSeq Acc Id: XP_005373046   ⟸   XM_005372989
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VBZ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366477   ⟸   XM_013511023
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013366476   ⟸   XM_013511022
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSCLAP00000010515   ⟸   ENSCLAT00000010646
Protein Domains
Alpha-type protein kinase   Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007258 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010646 ENTREZGENE
  ENSCLAT00000010646.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  MHCK/EF2 kinase UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  MHCK_EF2_kinase UniProtKB/TrEMBL
NCBI Gene Alpk2 ENTREZGENE
PANTHER ALPHA-PROTEIN KINASE 2 UniProtKB/TrEMBL
  ALPHA-PROTEIN KINASE 2-RELATED UniProtKB/TrEMBL
Pfam Alpha_kinase UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
PROSITE ALPHA_KINASE UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
SMART Alpha_kinase UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2VBZ2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Alpk2  alpha kinase 2    alpha-kinase 2  Symbol and/or name change 5135510 APPROVED