Rnf43 (ring finger protein 43) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Rnf43 (ring finger protein 43) Rattus norvegicus
Analyze
Symbol: Rnf43
Name: ring finger protein 43
RGD ID: 1305204
Description: Predicted to enable frizzled binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including Wnt receptor catabolic process; stem cell proliferation; and ubiquitin-dependent protein catabolic process. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in endometrial cancer; gastrointestinal system cancer (multiple); irritable bowel syndrome; lung adenocarcinoma; and villous adenoma. Orthologous to human RNF43 (ring finger protein 43); PARTICIPATES IN Wnt signaling, canonical pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase RNF43; LOC303412; RGD1305204; similar to hypothetical protein FLJ20315
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Bp308
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81072,958,744 - 73,034,540 (+)NCBIGRCr8
mRatBN7.21072,461,508 - 72,537,301 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1072,464,348 - 72,536,977 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1077,076,871 - 77,146,437 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01076,581,783 - 76,651,384 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01072,046,299 - 72,115,890 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01074,956,411 - 75,028,951 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1074,959,285 - 75,028,951 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01075,073,437 - 75,145,501 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41075,957,792 - 76,027,392 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11075,970,268 - 76,041,762 (+)NCBI
Celera1071,380,030 - 71,449,285 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
C60 fullerene  (EXP)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
chrysene  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethylparaben  (ISO)
genistein  (ISO)
gentamycin  (EXP)
leflunomide  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
oxaliplatin  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
plasma membrane  (IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis. Bond CE, etal., Oncotarget. 2016 Oct 25;7(43):70589-70600. doi: 10.18632/oncotarget.12130.
2. Impact of loss-of-function mutations at the RNF43 locus on colorectal cancer development and progression. Eto T, etal., J Pathol. 2018 Aug;245(4):445-455. doi: 10.1002/path.5098. Epub 2018 Jun 20.
3. Genomic landscape of colitis-associated cancer indicates the impact of chronic inflammation and its stratification by mutations in the Wnt signaling. Fujita M, etal., Oncotarget. 2017 Dec 12;9(1):969-981. doi: 10.18632/oncotarget.22867. eCollection 2018 Jan 2.
4. Germline mutations in oncogene-induced senescence pathways are associated with multiple sessile serrated adenomas. Gala MK, etal., Gastroenterology. 2014 Feb;146(2):520-9.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. RNF43 is frequently mutated in colorectal and endometrial cancers. Giannakis M, etal., Nat Genet. 2014 Dec;46(12):1264-6. doi: 10.1038/ng.3127. Epub 2014 Oct 26.
7. DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer. Huang S, etal., Cancer Res. 2017 Dec 1;77(23):6562-6575. doi: 10.1158/0008-5472.CAN-17-1570. Epub 2017 Oct 11.
8. Frequent frameshift mutations in 2 mononucleotide repeats of RNF43 gene and its regional heterogeneity in gastric and colorectal cancers. Jo YS, etal., Hum Pathol. 2015 Nov;46(11):1640-6. doi: 10.1016/j.humpath.2015.07.004. Epub 2015 Jul 15.
9. Cytotoxic T lymphocyte response to peptide vaccination predicts survival in stage III colorectal cancer. Kawamura J, etal., Cancer Sci. 2018 May;109(5):1545-1551. doi: 10.1111/cas.13547. Epub 2018 Mar 31.
10. The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated beta-catenin by sequestering TCF4 to the nuclear membrane. Loregger A, etal., Sci Signal. 2015 Sep 8;8(393):ra90. doi: 10.1126/scisignal.aac6757.
11. RNF43 mutation is associated with aggressive tumor biology along with BRAF V600E mutation in right-sided colorectal cancer. Matsumoto A, etal., Oncol Rep. 2020 Jun;43(6):1853-1862. doi: 10.3892/or.2020.7561. Epub 2020 Mar 23.
12. RT-qPCR analysis of the tumor antigens TOMM34 and RNF43 in samples extracted from paraffin-embedded specimens of colorectal cancer. Matsushita N, etal., Oncol Lett. 2017 Aug;14(2):2281-2287. doi: 10.3892/ol.2017.6412. Epub 2017 Jun 19.
13. Dysregulated Wnt signalling and recurrent mutations of the tumour suppressor RNF43 in early gastric carcinogenesis. Min BH, etal., J Pathol. 2016 Nov;240(3):304-314. doi: 10.1002/path.4777.
14. Mutated Rnf43 Aggravates Helicobacter Pylori-Induced Gastric Pathology. Neumeyer V, etal., Cancers (Basel). 2019 Mar 16;11(3). pii: cancers11030372. doi: 10.3390/cancers11030372.
15. Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells. Neumeyer V, etal., Carcinogenesis. 2019 Jun 10;40(4):551-559. doi: 10.1093/carcin/bgy152.
16. The complex world of WNT receptor signalling. Niehrs C Nat Rev Mol Cell Biol. 2012 Dec;13(12):767-79. doi: 10.1038/nrm3470. Epub 2012 Nov 15.
17. RNF43 Inhibits Cancer Cell Proliferation and Could be a Potential Prognostic Factor for Human Gastric Carcinoma. Niu L, etal., Cell Physiol Biochem. 2015;36(5):1835-46.
18. Phase I clinical trial of a novel peptide vaccine in combination with UFT/LV for metastatic colorectal cancer. Okuno K, etal., Exp Ther Med. 2011 Jan;2(1):73-79. doi: 10.3892/etm.2010.182. Epub 2010 Dec 2.
19. [Preliminary study of Peptide vaccine with UFT/LV as adjuvant setting for stage III colorectal cancer]. Okuno K, etal., Gan To Kagaku Ryoho. 2011 Nov;38(12):1906-8.
20. Exome sequencing of liver fluke-associated cholangiocarcinoma. Ong CK, etal., Nat Genet. 2012 May 6;44(6):690-3. doi: 10.1038/ng.2273.
21. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
22. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
23. Comprehensive gene review and curation RGD comprehensive gene curation
24. [Clinical study of Peptide-cocktail vaccination with tegafur-uracil/leucovorin for advanced colorectal cancer]. Sugiura F, etal., Gan To Kagaku Ryoho. 2012 Nov;39(12):1760-2.
25. Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development. Takeda H, etal., Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2057-65. doi: 10.1073/pnas.1603223113. Epub 2016 Mar 22.
26. Ring finger protein 43 expression is associated with genetic alteration status and poor prognosis among patients with intrahepatic cholangiocarcinoma. Talabnin C, etal., Hum Pathol. 2016 Jun;52:47-54. doi: 10.1016/j.humpath.2015.12.027. Epub 2016 Feb 1.
27. Wild-type APC Is Associated with Poor Survival in Metastatic Microsatellite Stable Colorectal Cancer. Wang C, etal., Oncologist. 2021 Mar;26(3):208-214. doi: 10.1002/onco.13607. Epub 2020 Dec 7.
28. Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. Wang K, etal., Nat Genet. 2014 Jun;46(6):573-82. doi: 10.1038/ng.2983. Epub 2014 May 11.
29. Reduced Frequency and Prognostic Significance of Ring Finger Protein 43 Nucleotide Polymorphisms in a Chinese Colorectal Cancer Cohort. Wen D, etal., DNA Cell Biol. 2019 Jun;38(6):541-548. doi: 10.1089/dna.2019.4645. Epub 2019 May 28.
30. Downregulation of ring-finger protein 43 in glioma associates with poor prognosis. Xi S, etal., Int J Clin Exp Pathol. 2015 Jan 1;8(1):490-6. eCollection 2015.
31. Reversing effect of ring finger protein 43 inhibition on malignant phenotypes of human hepatocellular carcinoma. Xing C, etal., Mol Cancer Ther. 2013 Jan;12(1):94-103. doi: 10.1158/1535-7163.MCT-12-0672. Epub 2012 Nov 6.
32. Germline Profiling and Molecular Characterization of Early Onset Metastatic Colorectal Cancer. Xu T, etal., Front Oncol. 2020 Oct 19;10:568911. doi: 10.3389/fonc.2020.568911. eCollection 2020.
33. RNF43 ubiquitinates and degrades phosphorylated E-cadherin by c-Src to facilitate epithelial-mesenchymal transition in lung adenocarcinoma. Zhang Y, etal., BMC Cancer. 2019 Jul 8;19(1):670. doi: 10.1186/s12885-019-5880-1.
Additional References at PubMed
PMID:22575959   PMID:22895187  


Genomics

Comparative Map Data
Rnf43
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81072,958,744 - 73,034,540 (+)NCBIGRCr8
mRatBN7.21072,461,508 - 72,537,301 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1072,464,348 - 72,536,977 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1077,076,871 - 77,146,437 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01076,581,783 - 76,651,384 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01072,046,299 - 72,115,890 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01074,956,411 - 75,028,951 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1074,959,285 - 75,028,951 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01075,073,437 - 75,145,501 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41075,957,792 - 76,027,392 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11075,970,268 - 76,041,762 (+)NCBI
Celera1071,380,030 - 71,449,285 (+)NCBICelera
Cytogenetic Map10q26NCBI
RNF43
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381758,352,500 - 58,417,534 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1758,353,676 - 58,417,595 (-)EnsemblGRCh38hg38GRCh38
GRCh371756,429,861 - 56,494,895 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361753,786,036 - 53,849,893 (-)NCBINCBI36Build 36hg18NCBI36
Celera1752,892,826 - 52,956,720 (-)NCBICelera
Cytogenetic Map17q22NCBI
HuRef1751,791,664 - 51,855,538 (-)NCBIHuRef
CHM1_11756,496,051 - 56,559,939 (-)NCBICHM1_1
T2T-CHM13v2.01759,220,375 - 59,286,465 (-)NCBIT2T-CHM13v2.0
Rnf43
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391187,553,913 - 87,626,365 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1187,553,548 - 87,626,365 (+)EnsemblGRCm39 Ensembl
GRCm381187,663,087 - 87,735,539 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1187,662,722 - 87,735,539 (+)EnsemblGRCm38mm10GRCm38
MGSCv371187,476,589 - 87,549,041 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361187,516,092 - 87,551,733 (+)NCBIMGSCv36mm8
Celera1197,258,357 - 97,331,075 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1152.17NCBI
Rnf43
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554514,604,985 - 4,680,762 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554514,604,985 - 4,680,762 (+)NCBIChiLan1.0ChiLan1.0
RNF43
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21974,524,931 - 74,588,376 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11779,336,108 - 79,399,545 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01752,420,516 - 52,492,813 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11757,276,761 - 57,347,748 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1757,276,761 - 57,347,748 (-)Ensemblpanpan1.1panPan2
RNF43
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1932,996,668 - 33,061,781 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl932,997,937 - 33,060,313 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha932,233,662 - 32,298,953 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0933,804,112 - 33,869,488 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl933,805,560 - 33,867,835 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1932,590,253 - 32,654,698 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0932,872,945 - 32,938,201 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0932,966,428 - 33,031,867 (-)NCBIUU_Cfam_GSD_1.0
Rnf43
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560232,332,381 - 32,394,172 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364904,683,725 - 4,741,828 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364904,660,904 - 4,742,669 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF43
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1234,635,228 - 34,694,378 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11234,631,574 - 34,695,021 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21236,120,577 - 36,181,757 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF43
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11634,981,126 - 35,046,478 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1634,980,922 - 35,045,107 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660775,794,244 - 5,861,143 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf43
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624871191,546 - 259,120 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624871191,534 - 259,134 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnf43
208 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:35
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000010296
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631565Hcuc4Hepatic copper content QTL 44.15liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106694181373452992Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105166340575085664Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
12903245Cm110Cardiac mass QTL 1100.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)107111521772606468Rat
12903246Cm111Cardiac mass QTL 1110.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)107111521772606468Rat
12903247Cm112Cardiac mass QTL 1120.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)107111521772606468Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
12902615Bw185Body weight QTL 1850.01body mass (VT:0001259)body weight (CMO:0000012)107111521772606468Rat
12903248Am14Aortic mass QTL 140.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)107111521772606468Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
12903249Kidm68Kidney mass QTL 680.02kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)107111521772606468Rat
1579918Bp279Blood pressure QTL 2790.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107111521772606468Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1072224939107211142Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1069738412107211142Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1069738412107211142Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072224939107211142Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106674365598003205Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)104944455181709989Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106134527698211570Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1069738412107211142Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1064890616107211142Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2298481Eau9Experimental allergic uveoretinitis QTL 90.0169uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)106592723382565079Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068420376107211142Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)106134527681714865Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106134541382564856Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070199100107211142Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106750210873579767Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)106134527699703528Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104194452678307017Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)104944455181709989Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104944455181709989Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)106134527699703528Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)104287676679813922Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068383129107211142Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat

Markers in Region
D10Chm6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21072,508,825 - 72,509,024 (+)MAPPERmRatBN7.2
Rnor_6.01076,556,439 - 76,556,637NCBIRnor6.0
Rnor_6.01075,001,953 - 75,002,151NCBIRnor6.0
Rnor_5.01075,100,237 - 75,100,435UniSTSRnor5.0
Rnor_5.01076,438,363 - 76,438,561UniSTSRnor5.0
RGSC_v3.41076,000,249 - 76,000,447UniSTSRGSC3.4
Celera1071,422,487 - 71,422,685UniSTS
Cytogenetic Map10q26UniSTS
D10Chm34  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21072,495,586 - 72,495,766 (+)MAPPERmRatBN7.2
Rnor_6.01074,988,717 - 74,988,896NCBIRnor6.0
Rnor_5.01075,113,491 - 75,113,671NCBIRnor5.0
RGSC_v3.41075,987,012 - 75,987,191UniSTSRGSC3.4
Celera1071,409,248 - 71,409,429UniSTS
Cytogenetic Map10q26UniSTS
D10Chm7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21072,506,089 - 72,506,294 (+)MAPPERmRatBN7.2
Rnor_6.01076,553,704 - 76,553,908NCBIRnor6.0
Rnor_6.01074,999,218 - 74,999,422NCBIRnor6.0
Rnor_5.01075,102,966 - 75,103,170UniSTSRnor5.0
Rnor_5.01076,435,628 - 76,435,832UniSTSRnor5.0
RGSC_v3.41075,997,514 - 75,997,718UniSTSRGSC3.4
Celera1071,419,752 - 71,419,956UniSTS
Cytogenetic Map10q26UniSTS
D10Chm16  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21072,469,183 - 72,469,453 (+)MAPPERmRatBN7.2
Rnor_6.01074,962,107 - 74,962,374NCBIRnor6.0
Rnor_5.01075,140,014 - 75,140,281UniSTSRnor5.0
RGSC_v3.41075,960,614 - 75,960,881UniSTSRGSC3.4
Celera1071,382,852 - 71,383,119UniSTS
Cytogenetic Map10q26UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000010296   ⟹   ENSRNOP00000010296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1072,466,362 - 72,536,977 (+)Ensembl
Rnor_6.0 Ensembl1074,959,285 - 75,028,951 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105746   ⟹   ENSRNOP00000095208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1072,464,348 - 72,536,977 (+)Ensembl
RefSeq Acc Id: NM_001135921   ⟹   NP_001129393
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,963,366 - 73,034,540 (+)NCBI
mRatBN7.21072,466,113 - 72,537,301 (+)NCBI
Rnor_6.01074,959,285 - 75,028,951 (+)NCBI
Rnor_5.01075,073,437 - 75,145,501 (-)NCBI
RGSC_v3.41075,957,792 - 76,027,392 (+)RGD
Celera1071,380,030 - 71,449,285 (+)RGD
Sequence:
RefSeq Acc Id: XM_006247090   ⟹   XP_006247152
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,744 - 73,032,951 (+)NCBI
mRatBN7.21072,461,508 - 72,535,927 (+)NCBI
Rnor_6.01074,956,411 - 75,027,315 (+)NCBI
Rnor_5.01075,073,437 - 75,145,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247091   ⟹   XP_006247153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,744 - 73,032,951 (+)NCBI
mRatBN7.21072,461,508 - 72,535,927 (+)NCBI
Rnor_6.01074,956,411 - 75,027,315 (+)NCBI
Rnor_5.01075,073,437 - 75,145,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247094   ⟹   XP_006247156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81073,022,202 - 73,032,951 (+)NCBI
mRatBN7.21072,526,394 - 72,535,927 (+)NCBI
Rnor_6.01075,019,417 - 75,027,315 (+)NCBI
Rnor_5.01075,073,437 - 75,145,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768041   ⟹   XP_008766263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81073,025,437 - 73,032,951 (+)NCBI
mRatBN7.21072,528,200 - 72,535,927 (+)NCBI
Rnor_6.01075,019,417 - 75,027,315 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039086050   ⟹   XP_038941978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,744 - 73,032,951 (+)NCBI
mRatBN7.21072,461,508 - 72,535,927 (+)NCBI
RefSeq Acc Id: XM_063269093   ⟹   XP_063125163
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,744 - 73,032,951 (+)NCBI
RefSeq Acc Id: XM_063269094   ⟹   XP_063125164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,749 - 73,034,540 (+)NCBI
RefSeq Acc Id: XM_063269095   ⟹   XP_063125165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,749 - 73,034,540 (+)NCBI
RefSeq Acc Id: XM_063269096   ⟹   XP_063125166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,749 - 73,034,540 (+)NCBI
RefSeq Acc Id: NP_001129393   ⟸   NM_001135921
- Peptide Label: precursor
- UniProtKB: A0A8I6AML0 (UniProtKB/TrEMBL),   A6HHU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247153   ⟸   XM_006247091
- Peptide Label: isoform X1
- UniProtKB: A6HHU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247152   ⟸   XM_006247090
- Peptide Label: isoform X1
- UniProtKB: A6HHU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247156   ⟸   XM_006247094
- Peptide Label: isoform X3
- UniProtKB: D3ZP81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766263   ⟸   XM_008768041
- Peptide Label: isoform X3
- UniProtKB: D3ZP81 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010296   ⟸   ENSRNOT00000010296
RefSeq Acc Id: XP_038941978   ⟸   XM_039086050
- Peptide Label: isoform X1
- UniProtKB: A6HHU8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095208   ⟸   ENSRNOT00000105746
RefSeq Acc Id: XP_063125163   ⟸   XM_063269093
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063125164   ⟸   XM_063269094
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AML0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125165   ⟸   XM_063269095
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AML0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125166   ⟸   XM_063269096
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AML0 (UniProtKB/TrEMBL)
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZP81-F1-model_v2 AlphaFold D3ZP81 1-782 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305204 AgrOrtholog
BioCyc Gene G2FUF-23749 BioCyc
Ensembl Genes ENSRNOG00000007606 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010296.6 UniProtKB/TrEMBL
  ENSRNOT00000105746.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  3.50.30.30 UniProtKB/TrEMBL
InterPro RNF43_Znf_RING UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  ZNRF-3_ecto UniProtKB/TrEMBL
  ZNRF3_Arkadia_E3_ligases UniProtKB/TrEMBL
KEGG Report rno:303412 UniProtKB/TrEMBL
NCBI Gene 303412 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNF43 UniProtKB/TrEMBL
  RING ZINC FINGER UniProtKB/TrEMBL
Pfam zf-RING_2 UniProtKB/TrEMBL
  ZNRF_3_ecto UniProtKB/TrEMBL
PhenoGen Rnf43 PhenoGen
PROSITE ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007606 RatGTEx
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A8I6AML0 ENTREZGENE, UniProtKB/TrEMBL
  A6HHU8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZP81 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Rnf43  ring finger protein 43   Rnf43_predicted  ring finger protein 43 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Rnf43_predicted  ring finger protein 43 (predicted)  RGD1305204_predicted  similar to hypothetical protein FLJ20315 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1305204_predicted  similar to hypothetical protein FLJ20315 (predicted)  LOC303412_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC303412_predicted  similar to hypothetical protein FLJ20315 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL