Agr2 (anterior gradient 2, protein disulphide isomerase family member) - Rat Genome Database

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Gene: Agr2 (anterior gradient 2, protein disulphide isomerase family member) Rattus norvegicus
Analyze
Symbol: Agr2
Name: anterior gradient 2, protein disulphide isomerase family member
RGD ID: 1304606
Description: Predicted to enable dystroglycan binding activity; epidermal growth factor receptor binding activity; and identical protein binding activity. Predicted to be involved in several processes, including positive regulation of cell-substrate adhesion; positive regulation of protein localization to plasma membrane; and positive regulation of signal transduction. Predicted to act upstream of or within inflammatory response; lung goblet cell differentiation; and mucus secretion. Predicted to be located in extracellular space. Predicted to be active in endoplasmic reticulum. Orthologous to human AGR2 (anterior gradient 2, protein disulphide isomerase family member); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 3,3',5,5'-tetrabromobisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: anterior gradient 2; anterior gradient 2 (Xenopus laevis) ; anterior gradient 2 homolog; anterior gradient 2 homolog (Xenopus laevis); anterior gradient homolog 2; anterior gradient homolog 2 (Xenopus laevis); anterior gradient protein 2 homolog; LOC298961
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8658,435,908 - 58,456,678 (+)NCBIGRCr8
mRatBN7.2652,708,602 - 52,729,378 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl652,708,602 - 52,729,371 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx652,999,619 - 53,020,416 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0653,314,493 - 53,335,286 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0652,779,800 - 52,800,569 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0655,465,782 - 55,487,087 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl655,465,782 - 55,487,714 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0665,081,213 - 65,102,524 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4654,695,633 - 54,716,858 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1654,709,609 - 54,719,927 (+)NCBI
Celera651,855,174 - 51,875,917 (+)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bicalutamide  (ISO)
bisphenol A  (EXP,ISO)
calcitriol  (ISO)
capecitabine  (ISO)
carbon monoxide  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloroprene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
coumestrol  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
dehydroepiandrosterone  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
disodium selenite  (ISO)
doxifluridine  (ISO)
Enterolactone  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (EXP)
genistein  (ISO)
glycidyl methacrylate  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
menadione  (ISO)
methimazole  (EXP)
nitrofen  (EXP)
O-methyleugenol  (ISO)
octadecanoic acid  (ISO)
ozone  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
sulfur dioxide  (ISO)
tamoxifen  (ISO)
tanespimycin  (ISO)
testosterone  (EXP,ISO)
titanium dioxide  (ISO)
trametinib  (ISO)
trichloroethene  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
triticonazole  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients. Innes HE, etal., Br J Cancer. 2006 Apr 10;94(7):1057-65.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Prognostic significance of AGR2 in pancreatic ductal adenocarcinoma. Riener MO, etal., Histol Histopathol. 2009 Sep;24(9):1121-8.
7. Analysis of the pancreatic tumor progression by a quantitative proteomic approach and immunhistochemical validation. Sitek B, etal., J Proteome Res. 2009 Apr;8(4):1647-56.
Additional References at PubMed
PMID:12592373   PMID:18614015   PMID:19359471   PMID:22184114   PMID:22675208   PMID:23220234   PMID:23274113   PMID:24251762   PMID:25666625   PMID:26169982  


Genomics

Comparative Map Data
Agr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8658,435,908 - 58,456,678 (+)NCBIGRCr8
mRatBN7.2652,708,602 - 52,729,378 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl652,708,602 - 52,729,371 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx652,999,619 - 53,020,416 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0653,314,493 - 53,335,286 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0652,779,800 - 52,800,569 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0655,465,782 - 55,487,087 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl655,465,782 - 55,487,714 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0665,081,213 - 65,102,524 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4654,695,633 - 54,716,858 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1654,709,609 - 54,719,927 (+)NCBI
Celera651,855,174 - 51,875,917 (+)NCBICelera
Cytogenetic Map6q16NCBI
AGR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38716,791,811 - 16,804,999 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl716,791,811 - 16,833,433 (-)EnsemblGRCh38hg38GRCh38
GRCh37716,831,435 - 16,844,623 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36716,797,960 - 16,811,133 (-)NCBINCBI36Build 36hg18NCBI36
Build 34716,604,675 - 16,617,848NCBI
Celera716,812,569 - 16,825,043 (-)NCBICelera
Cytogenetic Map7p21.1NCBI
HuRef716,719,359 - 16,731,797 (-)NCBIHuRef
CHM1_1716,833,176 - 16,845,615 (-)NCBICHM1_1
T2T-CHM13v2.0716,921,380 - 16,934,682 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2716,885,921 - 16,898,395 (-)NCBI
Agr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391236,042,924 - 36,054,080 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1236,042,906 - 36,054,086 (+)EnsemblGRCm39 Ensembl
GRCm381235,992,925 - 36,004,081 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1235,992,907 - 36,004,087 (+)EnsemblGRCm38mm10GRCm38
MGSCv371236,719,512 - 36,730,668 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361236,503,191 - 36,514,347 (+)NCBIMGSCv36mm8
Celera1237,446,354 - 37,457,458 (+)NCBICelera
Cytogenetic Map12A3NCBI
cM Map1216.18NCBI
Agr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541019,984,768 - 19,995,733 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541019,984,768 - 19,995,446 (-)NCBIChiLan1.0ChiLan1.0
AGR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2621,624,614 - 21,637,773 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1769,949,337 - 69,962,590 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0717,446,275 - 17,489,802 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1716,773,281 - 16,785,721 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl716,773,281 - 16,785,879 (-)Ensemblpanpan1.1panPan2
AGR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11431,303,784 - 31,316,752 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1431,305,567 - 31,316,686 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1430,825,073 - 30,838,046 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01431,224,288 - 31,237,241 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1431,226,071 - 31,237,170 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11431,326,448 - 31,339,401 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01431,038,306 - 31,051,283 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01431,351,630 - 31,364,787 (-)NCBIUU_Cfam_GSD_1.0
Agr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511875,641,522 - 75,654,857 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365463,315,543 - 3,328,369 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365463,316,622 - 3,328,317 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl986,041,369 - 86,053,857 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1986,042,070 - 86,053,893 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2994,843,416 - 94,855,248 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AGR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12141,311,250 - 41,324,806 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2141,312,415 - 41,326,663 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604263,184,604 - 63,199,875 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473913,428,130 - 13,442,070 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473913,428,049 - 13,440,949 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Agr2
137 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:33
Count of miRNA genes:29
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000006682
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)63569161857730540Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat

Markers in Region
D6Got62  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2652,718,280 - 52,718,455 (+)MAPPERmRatBN7.2
Rnor_6.0655,475,496 - 55,475,670NCBIRnor6.0
Rnor_5.0665,090,927 - 65,091,101UniSTSRnor5.0
RGSC_v3.4654,705,768 - 54,705,942UniSTSRGSC3.4
RGSC_v3.4654,705,767 - 54,705,942RGDRGSC3.4
RGSC_v3.1654,708,894 - 54,709,068RGD
Celera651,864,827 - 51,865,001UniSTS
RH 3.4 Map6349.6UniSTS
RH 3.4 Map6349.6RGD
RH 2.0 Map6548.2RGD
Cytogenetic Map6q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 9 47 56 39 45 14 25 14 6 145 84 43 30 56 31

Sequence


Ensembl Acc Id: ENSRNOT00000006682   ⟹   ENSRNOP00000006682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl652,708,602 - 52,729,371 (+)Ensembl
Rnor_6.0 Ensembl655,465,782 - 55,487,086 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091213   ⟹   ENSRNOP00000068828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl655,479,283 - 55,487,714 (+)Ensembl
RefSeq Acc Id: NM_001106725   ⟹   NP_001100195
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8658,435,908 - 58,456,677 (+)NCBI
mRatBN7.2652,708,602 - 52,729,371 (+)NCBI
Rnor_6.0655,465,782 - 55,487,086 (+)NCBI
Rnor_5.0665,081,213 - 65,102,524 (+)NCBI
RGSC_v3.4654,695,633 - 54,716,858 (+)RGD
Celera651,855,174 - 51,875,917 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240041   ⟹   XP_006240103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8658,446,052 - 58,456,678 (+)NCBI
mRatBN7.2652,718,809 - 52,729,378 (+)NCBI
Rnor_6.0655,472,328 - 55,487,087 (+)NCBI
Rnor_5.0665,081,213 - 65,102,524 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001100195 (Get FASTA)   NCBI Sequence Viewer  
  NP_001421172 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240103 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03309 (Get FASTA)   NCBI Sequence Viewer  
  EDM03310 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006682.5
RefSeq Acc Id: NP_001100195   ⟸   NM_001106725
- Peptide Label: precursor
- UniProtKB: D3ZIA7 (UniProtKB/TrEMBL),   A6HBA4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240103   ⟸   XM_006240041
- Peptide Label: isoform X1
- UniProtKB: D3ZIA7 (UniProtKB/TrEMBL),   A6HBA4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006682   ⟸   ENSRNOT00000006682
Ensembl Acc Id: ENSRNOP00000068828   ⟸   ENSRNOT00000091213

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIA7-F1-model_v2 AlphaFold D3ZIA7 1-175 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694566
Promoter ID:EPDNEW_R5083
Type:single initiation site
Name:Agr2_1
Description:anterior gradient 2, protein disulphide isomerase family member
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0655,479,307 - 55,479,367EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304606 AgrOrtholog
BioCyc Gene G2FUF-37804 BioCyc
Ensembl Genes ENSRNOG00000005023 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006682.7 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro AGR/TXD UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
KEGG Report rno:298961 UniProtKB/TrEMBL
NCBI Gene 298961 ENTREZGENE
PANTHER ANTERIOR GRADIENT PROTEIN 2 HOMOLOG UniProtKB/TrEMBL
  ANTERIOR GRADIENT PROTEIN-RELATED UniProtKB/TrEMBL
Pfam Thioredoxin_7 UniProtKB/TrEMBL
PhenoGen Agr2 PhenoGen
RatGTEx ENSRNOG00000005023 RatGTEx
Superfamily-SCOP Thiordxn-like_fd UniProtKB/TrEMBL
UniProt A6HBA4 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIA7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-09 Agr2  anterior gradient 2, protein disulphide isomerase family member  Agr2  anterior gradient 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-07 Agr2  anterior gradient 2  Agr2  anterior gradient 2 homolog (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-12-06 Agr2  anterior gradient 2 homolog (Xenopus laevis)  Agr2  anterior gradient homolog 2 (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Agr2  anterior gradient homolog 2 (Xenopus laevis)  Agr2  anterior gradient 2 (Xenopus laevis)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Agr2  anterior gradient 2 (Xenopus laevis)   Agr2_predicted  anterior gradient 2 (Xenopus laevis) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Agr2_predicted  anterior gradient 2 (Xenopus laevis) (predicted)      Symbol and Name status set to approved 70820 APPROVED