AGR2 (anterior gradient 2, protein disulphide isomerase family member) - Rat Genome Database

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Gene: AGR2 (anterior gradient 2, protein disulphide isomerase family member) Pan paniscus
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Symbol: AGR2
Name: anterior gradient 2, protein disulphide isomerase family member
RGD ID: 11758050
Description: ENCODES a protein that exhibits dystroglycan binding (inferred); epidermal growth factor receptor binding (inferred); identical protein binding (inferred); INVOLVED IN inflammatory response (ortholog); lung goblet cell differentiation (ortholog); mucus secretion (ortholog); ASSOCIATED WITH breast cancer (ortholog); Breast Neoplasms (ortholog); pancreatic ductal adenocarcinoma (ortholog); FOUND IN endoplasmic reticulum (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: anterior gradient 2 homolog; anterior gradient protein 2 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2621,624,614 - 21,637,773 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1769,949,337 - 69,962,590 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0717,446,275 - 17,489,802 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1716,773,281 - 16,785,721 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl716,773,281 - 16,785,879 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
AGR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2621,624,614 - 21,637,773 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1769,949,337 - 69,962,590 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0717,446,275 - 17,489,802 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1716,773,281 - 16,785,721 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl716,773,281 - 16,785,879 (-)Ensemblpanpan1.1panPan2
AGR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38716,791,811 - 16,804,999 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl716,791,811 - 16,833,433 (-)EnsemblGRCh38hg38GRCh38
GRCh37716,831,435 - 16,844,623 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36716,797,960 - 16,811,133 (-)NCBINCBI36Build 36hg18NCBI36
Build 34716,604,675 - 16,617,848NCBI
Celera716,812,569 - 16,825,043 (-)NCBICelera
Cytogenetic Map7p21.1NCBI
HuRef716,719,359 - 16,731,797 (-)NCBIHuRef
CHM1_1716,833,176 - 16,845,615 (-)NCBICHM1_1
T2T-CHM13v2.0716,921,380 - 16,934,682 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2716,885,921 - 16,898,395 (-)NCBI
Agr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391236,042,924 - 36,054,080 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1236,042,906 - 36,054,086 (+)EnsemblGRCm39 Ensembl
GRCm381235,992,925 - 36,004,081 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1235,992,907 - 36,004,087 (+)EnsemblGRCm38mm10GRCm38
MGSCv371236,719,512 - 36,730,668 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361236,503,191 - 36,514,347 (+)NCBIMGSCv36mm8
Celera1237,446,354 - 37,457,458 (+)NCBICelera
Cytogenetic Map12A3NCBI
cM Map1216.18NCBI
Agr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8658,435,908 - 58,456,678 (+)NCBIGRCr8
mRatBN7.2652,708,602 - 52,729,378 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl652,708,602 - 52,729,371 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx652,999,619 - 53,020,416 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0653,314,493 - 53,335,286 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0652,779,800 - 52,800,569 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0655,465,782 - 55,487,087 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl655,465,782 - 55,487,714 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0665,081,213 - 65,102,524 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4654,695,633 - 54,716,858 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1654,709,609 - 54,719,927 (+)NCBI
Celera651,855,174 - 51,875,917 (+)NCBICelera
Cytogenetic Map6q16NCBI
Agr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541019,984,768 - 19,995,733 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541019,984,768 - 19,995,446 (-)NCBIChiLan1.0ChiLan1.0
AGR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11431,303,784 - 31,316,752 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1431,305,567 - 31,316,686 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1430,825,073 - 30,838,046 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01431,224,288 - 31,237,241 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1431,226,071 - 31,237,170 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11431,326,448 - 31,339,401 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01431,038,306 - 31,051,283 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01431,351,630 - 31,364,787 (-)NCBIUU_Cfam_GSD_1.0
Agr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511875,641,522 - 75,654,857 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365463,315,543 - 3,328,369 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365463,316,622 - 3,328,317 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl986,041,369 - 86,053,857 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1986,042,070 - 86,053,893 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2994,843,416 - 94,855,248 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AGR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12141,311,250 - 41,324,806 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2141,312,415 - 41,326,663 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604263,184,604 - 63,199,875 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473913,428,130 - 13,442,070 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473913,428,049 - 13,440,949 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000051722   ⟹   ENSPPAP00000028873
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl716,773,281 - 16,785,721 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000051738   ⟹   ENSPPAP00000028890
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl716,773,550 - 16,785,879 (-)Ensembl
RefSeq Acc Id: XM_057302734   ⟹   XP_057158717
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2621,624,614 - 21,637,773 (-)NCBI
NHGRI_mPanPan1769,949,337 - 69,962,590 (-)NCBI
Protein Sequences
Protein RefSeqs XP_057158717 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028873.1
  ENSPPAP00000028890.1
Ensembl Acc Id: ENSPPAP00000028890   ⟸   ENSPPAT00000051738
Ensembl Acc Id: ENSPPAP00000028873   ⟸   ENSPPAT00000051722
RefSeq Acc Id: XP_057158717   ⟸   XM_057302734
- UniProtKB: A0A2R9BHT2 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037458 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000051722.1 UniProtKB/TrEMBL
  ENSPPAT00000051738.1 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro AGR/TXD UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
NCBI Gene AGR2 ENTREZGENE
PANTHER ANTERIOR GRADIENT PROTEIN 2 HOMOLOG UniProtKB/TrEMBL
  ANTERIOR GRADIENT PROTEIN-RELATED UniProtKB/TrEMBL
Pfam Thioredoxin_7 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
UniProt A0A2R9BGW6_PANPA UniProtKB/TrEMBL
  A0A2R9BHT2 ENTREZGENE, UniProtKB/TrEMBL