ACE (angiotensin I converting enzyme) - Rat Genome Database

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Gene: ACE (angiotensin I converting enzyme) Canis lupus familiaris
Analyze
Symbol: ACE
Name: angiotensin I converting enzyme
RGD ID: 12187832
Description: ENCODES a protein that exhibits actin binding (ortholog); heterocyclic compound binding (ortholog); metallopeptidase activity (ortholog); INVOLVED IN angiogenesis involved in coronary vascular morphogenesis (ortholog); animal organ regeneration (ortholog); bradykinin catabolic process (ortholog); PARTICIPATES IN angiotensin (1-7) signaling pathway; angiotensin II signaling pathway; benazepril pharmacodynamics pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Acute Hepatitis (ortholog); acute kidney failure (ortholog); FOUND IN basal plasma membrane (ortholog); brush border membrane (ortholog); extracellular space (ortholog); INTERACTS WITH Ceronapril
Type: protein-coding
RefSeq Status: MODEL
Previously known as: angiotensin converting enzyme; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I converting enzyme 1; angiotensin-converting enzyme; DCP1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1911,497,182 - 11,516,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl911,497,182 - 11,516,358 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha912,457,866 - 12,477,045 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0913,160,704 - 13,179,888 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl913,160,704 - 13,200,795 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1912,105,344 - 12,124,523 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0915,407,255 - 15,426,429 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0915,410,134 - 15,429,354 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Acute Hepatitis  (ISO)
acute kidney failure  (ISO)
Acute Lung Injury  (ISO)
adenocarcinoma  (ISO)
adult respiratory distress syndrome  (ISO)
Albuminuria  (ISO)
alcohol-associated liver disease  (ISO)
allergic disease  (ISO)
allergic rhinitis  (ISO)
Alzheimer's disease  (ISO)
anemia  (ISO)
Angiotensin I-Converting Enzyme, Benign Serum Increase  (ISO)
ankylosing spondylitis  (ISO)
Arteriovenous Fistula  (ISO)
aspiration pneumonia  (ISO)
asthma  (ISO)
atrial fibrillation  (ISO)
autistic disorder  (ISO)
autosomal recessive polycystic kidney disease  (ISO)
Banti's Syndrome  (ISO)
Behcet's disease  (ISO)
berylliosis  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
bronchiolitis obliterans  (ISO)
CAKUT  (ISO)
Cardiac Arrhythmias  (ISO)
Cardiomegaly  (ISO)
cardiovascular system disease  (ISO)
celiac disease  (ISO)
Cerebral Hemorrhage  (ISO)
cerebral infarction  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
chemical colitis  (ISO)
Chemotherapy-Induced Febrile Neutropenia  (ISO)
cholestasis  (ISO)
Chronic Hepatitis C  (ISO)
Chronic Intermittent Hypoxia  (ISO)
chronic myeloid leukemia  (ISO)
chronic obstructive pulmonary disease  (ISO)
coarctation of the aorta  (ISO)
congenital diaphragmatic hernia  (ISO)
Congenital Hepatic Fibrosis  (ISO)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
coronary restenosis  (ISO)
Coronavirus infectious disease  (ISO)
Cough  (ISO)
COVID-19  (ISO)
Cytomegalovirus Infections  (ISO)
diabetic angiopathy  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
diastolic heart failure  (ISO)
diffuse cystic renal dysplasia  (ISO)
dilated cardiomyopathy  (ISO)
drug allergy  (ISO)
end stage renal disease  (ISO)
endomyocardial fibrosis  (ISO)
Endotoxemia  (ISO)
Experimental Arthritis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
extrinsic allergic alveolitis  (ISO)
Fabry disease  (ISO)
Familial Cerebral Cavernous Malformation  (ISO)
familial Mediterranean fever  (ISO)
Fetal Death  (ISO)
Fetal Growth Retardation  (ISO)
focal segmental glomerulosclerosis 1  (ISO)
gallbladder adenocarcinoma  (ISO)
Gaucher's disease  (ISO)
genetic disease  (ISO)
Genetic Predisposition to Disease  (ISO)
glomerulonephritis  (ISO)
glomerulosclerosis  (ISO)
glycogen storage disease V  (ISO)
heart valve disease  (ISO)
Helicobacter Infections  (ISO)
hepatitis A  (ISO)
hepatocellular carcinoma  (ISO)
Hyperoxia  (ISO)
hypertension  (ISO)
Hypertensive Nephrosclerosis  (ISO)
hypertrophic cardiomyopathy  (ISO)
Hypotension  (ISO)
IgA glomerulonephritis  (ISO)
IgA vasculitis  (ISO)
in situ carcinoma  (ISO)
intermediate coronary syndrome  (ISO)
Intestinal Reperfusion Injury  (ISO)
ischemic stroke  (ISO)
kidney disease  (ISO)
kidney failure  (ISO)
Kidney Reperfusion Injury  (ISO)
Left Ventricular Hypertrophy  (ISO)
leukemia  (ISO)
leukostasis  (ISO)
liver cirrhosis  (ISO)
Liver Metastasis  (ISO)
lung cancer  (ISO)
lung carcinoma  (ISO)
lung disease  (ISO)
Lung Injury  (ISO)
Lung Neoplasms  (ISO)
malaria  (ISO)
male infertility  (ISO)
Memory Disorders  (ISO)
Meningococcal Infections  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
microcephaly  (ISO)
middle cerebral artery infarction  (ISO)
mitral valve disease  (ISO)
mitral valve prolapse  (ISO)
multiple myeloma  (ISO)
Mycobacterium Infections  (ISO)
myocardial infarction  (ISO)
myocarditis  (ISO)
Neoplasm Metastasis  (ISO)
nephritis  (ISO)
nephrosis  (ISO)
nephrotic syndrome  (ISO)
non-arteritic anterior ischemic optic neuropathy  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
ocular hypotension  (ISO)
osteoporosis  (ISO)
Pain  (ISO)
pancreatic cancer  (ISO)
pancreatic ductal carcinoma  (ISO)
Peritoneal Fibrosis  (ISO)
Pleural Effusion  (ISO)
pneumonia  (ISO)
polycythemia  (ISO)
pre-eclampsia  (ISO)
pre-malignant neoplasm  (ISO)
Pregnancy-Induced Hypertension  (ISO)
Premature Infant Diseases  (ISO)
Prenatal Exposure Delayed Effects  (ISO)
primary biliary cholangitis  (ISO)
Prostatic Neoplasms  (ISO)
proteinuria  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
Puromycin Aminonucleoside Nephrosis  (ISO)
pyelonephritis  (ISO)
Radiation Nephropathy  (ISO)
renal fibrosis  (ISO)
Renal Tubular Dysgenesis  (ISO)
renovascular hypertension  (ISO)
Reperfusion Injury  (ISO)
respiratory system disease  (ISO)
Right Ventricular Hypertrophy  (ISO)
sarcoidosis  (ISO)
schizophrenia  (ISO)
Sepsis  (ISO)
severe acute respiratory syndrome  (ISO)
Staphylococcal Infections  (ISO)
stomach cancer  (ISO)
Stomach Neoplasms  (ISO)
stroke  (ISO)
subacute sclerosing panencephalitis  (ISO)
substance-induced psychosis  (ISO)
Sudden Death  (ISO)
systemic scleroderma  (ISO)
toxic shock syndrome  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ureteral obstruction  (ISO)
uveitis  (ISO)
Vascular System Injuries  (ISO)
Venous Thromboembolism  (ISO)
Ventricular Fibrillation  (ISO)
Ventricular Remodeling  (ISO)
viral pneumonia  (ISO)
Weight Gain  (ISO)
Weight Loss  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Ceronapril  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
amyloid-beta metabolic process  (IEA)
angiogenesis involved in coronary vascular morphogenesis  (ISO)
angiotensin maturation  (IBA,IEA)
angiotensin-activated signaling pathway  (IEA)
animal organ regeneration  (ISO)
arachidonate secretion  (IEA)
bradykinin catabolic process  (IEA,ISO)
cell proliferation in bone marrow  (IEA)
cellular response to aldosterone  (ISO)
cellular response to glucose stimulus  (ISO)
eating behavior  (ISO)
embryo development ending in birth or egg hatching  (ISO)
female pregnancy  (ISO)
heart contraction  (ISO)
hormone catabolic process  (IEA)
hormone metabolic process  (IEA)
kidney development  (IEA,ISO)
lung alveolus development  (ISO)
lung development  (ISO)
male gonad development  (IEA,ISO)
negative regulation of calcium ion import  (ISO)
negative regulation of D-glucose import across plasma membrane  (ISO)
negative regulation of gap junction assembly  (IEA)
negative regulation of gene expression  (IEA)
neutrophil mediated immunity  (ISO)
peptide catabolic process  (IEA,ISO)
peptide metabolic process  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of blood pressure  (ISO)
positive regulation of neurogenesis  (ISO)
positive regulation of systemic arterial blood pressure  (IBA,ISO)
positive regulation of vasoconstriction  (ISO)
post-transcriptional regulation of gene expression  (IEA)
proteolysis  (IEA)
regulation of angiotensin metabolic process  (IEA)
regulation of blood pressure  (IEA)
regulation of heart rate by cardiac conduction  (IEA)
regulation of hematopoietic stem cell proliferation  (IEA)
regulation of smooth muscle cell migration  (ISO)
regulation of synaptic plasticity  (IEA)
regulation of systemic arterial blood pressure by renin-angiotensin  (IEA)
response to dexamethasone  (ISO)
response to hypoxia  (ISO)
response to laminar fluid shear stress  (ISO)
response to lipopolysaccharide  (ISO)
response to nutrient levels  (ISO)
response to thyroid hormone  (ISO)
response to xenobiotic stimulus  (ISO)
spermatogenesis  (ISO)
substance P catabolic process  (IEA)
vasoconstriction  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:8855304   PMID:21846742   PMID:22301074   PMID:29069972   PMID:29200408   PMID:30032202  


Genomics

Comparative Map Data
ACE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1911,497,182 - 11,516,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl911,497,182 - 11,516,358 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha912,457,866 - 12,477,045 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0913,160,704 - 13,179,888 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl913,160,704 - 13,200,795 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1912,105,344 - 12,124,523 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0915,407,255 - 15,426,429 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0915,410,134 - 15,429,354 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
ACE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381763,477,061 - 63,498,373 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1763,477,058 - 63,498,380 (+)Ensemblhg38GRCh38
GRCh371761,554,422 - 61,575,734 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361758,908,166 - 58,928,711 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341758,915,908 - 58,952,935NCBI
Celera1755,942,475 - 55,963,778 (+)NCBICelera
Cytogenetic Map17q23.3NCBI
HuRef1756,922,781 - 56,944,100 (+)NCBIHuRef
CHM1_11761,618,550 - 61,639,869 (+)NCBICHM1_1
T2T-CHM13v2.01764,347,269 - 64,368,872 (+)NCBIT2T-CHM13v2.0
Ace
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911105,858,774 - 105,880,790 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11105,858,771 - 105,880,790 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3811105,967,948 - 105,989,964 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11105,967,945 - 105,989,964 (+)Ensemblmm10GRCm38
MGSCv3711105,829,261 - 105,851,259 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3611105,784,049 - 105,805,350 (+)NCBIMGSCv36mm8
Celera11117,699,475 - 117,721,491 (+)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1168.84NCBI
Ace
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81091,410,129 - 91,430,246 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1091,409,819 - 91,430,942 (+)EnsemblGRCr8
mRatBN7.21090,910,316 - 90,930,437 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1090,910,316 - 90,931,131 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1095,964,627 - 95,984,783 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01095,427,801 - 95,447,951 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01090,839,016 - 90,859,102 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1094,562,374 - 94,582,514 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1095,293,259 - 95,313,402 (+)NCBILyon_Normotensive
Lyon_Hypertensive1096,738,879 - 96,759,018 (+)NCBILyon_Hypertensive
F344_StmMcwi1096,844,324 - 96,864,470 (+)NCBIF344_StmMcwi
Rnor_6.01094,170,766 - 94,213,831 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1094,170,766 - 94,187,822 (+)Ensemblrn6Rnor6.0
Rnor_5.01093,922,062 - 93,965,127 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41095,361,338 - 95,381,455 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1089,588,544 - 89,608,666 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
ACE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21979,648,057 - 79,669,151 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11784,465,633 - 84,486,649 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01757,556,294 - 57,577,294 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11762,710,398 - 62,724,018 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1762,702,341 - 62,733,853 (+)EnsemblpanPan2panpan1.1
LOC101968921
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560215,017,159 - 15,036,742 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365414,157,393 - 4,178,177 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365414,157,847 - 4,178,156 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1215,394,487 - 15,414,703 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11215,394,487 - 15,414,609 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21215,381,362 - 15,401,171 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Ace
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624849998,277 - 1,019,521 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624849998,262 - 1,019,305 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in ACE
209 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003639249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038546924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038546925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038610895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038610896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038627179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038675956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038675957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF025473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ195091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U67199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000020636   ⟹   ENSCAFP00000019153
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl911,497,182 - 11,516,358 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000062288   ⟹   ENSCAFP00000048706
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl911,504,502 - 11,516,358 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000078864   ⟹   ENSCAFP00000053246
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl911,504,502 - 11,516,358 (+)Ensembl
RefSeq Acc Id: XM_003639249   ⟹   XP_003639297
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1911,497,182 - 11,516,362 (+)NCBI
Dog10K_Boxer_Tasha912,457,866 - 12,477,045 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038485116   ⟹   XP_038341044
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1912,105,344 - 12,124,523 (+)NCBI
RefSeq Acc Id: XM_038485117   ⟹   XP_038341045
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1912,112,605 - 12,124,219 (+)NCBI
RefSeq Acc Id: XM_038546924   ⟹   XP_038402852
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0915,410,134 - 15,429,354 (-)NCBI
RefSeq Acc Id: XM_038546925   ⟹   XP_038402853
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0915,410,438 - 15,422,075 (-)NCBI
RefSeq Acc Id: XM_038610895   ⟹   XP_038466823
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0915,407,255 - 15,426,429 (-)NCBI
RefSeq Acc Id: XM_038610896   ⟹   XP_038466824
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0915,407,559 - 15,419,167 (-)NCBI
RefSeq Acc Id: XM_038627179   ⟹   XP_038483107
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha912,465,131 - 12,476,741 (+)NCBI
RefSeq Acc Id: XM_038675956   ⟹   XP_038531884
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0913,160,704 - 13,179,888 (+)NCBI
RefSeq Acc Id: XM_038675957   ⟹   XP_038531885
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0913,167,966 - 13,179,584 (+)NCBI
RefSeq Acc Id: XP_003639297   ⟸   XM_003639249
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RHV4 (UniProtKB/TrEMBL),   A0A8C0SLR7 (UniProtKB/TrEMBL),   A0A8P0NF47 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000053246   ⟸   ENSCAFT00000078864
Ensembl Acc Id: ENSCAFP00000019153   ⟸   ENSCAFT00000020636
Ensembl Acc Id: ENSCAFP00000048706   ⟸   ENSCAFT00000062288
RefSeq Acc Id: XP_038341044   ⟸   XM_038485116
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038341045   ⟸   XM_038485117
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038466823   ⟸   XM_038610895
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038466824   ⟸   XM_038610896
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038531884   ⟸   XM_038675956
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RHV4 (UniProtKB/TrEMBL),   A0A8C0SLR7 (UniProtKB/TrEMBL),   A0A8P0NF47 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038531885   ⟸   XM_038675957
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SPL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038483107   ⟸   XM_038627179
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SPL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038402852   ⟸   XM_038546924
- Peptide Label: isoform X1
- UniProtKB: A0A8C0SLR7 (UniProtKB/TrEMBL),   A0A8P0NF47 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038402853   ⟸   XM_038546925
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SPL2 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012998 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010993 UniProtKB/TrEMBL
  ENSCAFG00040014301 UniProtKB/TrEMBL
  ENSCAFG00845018336 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000020636.5 UniProtKB/TrEMBL
  ENSCAFT00000062288.2 UniProtKB/TrEMBL
  ENSCAFT00000078864.2 UniProtKB/TrEMBL
  ENSCAFT00000095367.1 UniProtKB/TrEMBL
  ENSCAFT00000099806.1 UniProtKB/TrEMBL
  ENSCAFT00030021223.1 UniProtKB/TrEMBL
  ENSCAFT00030021562.1 UniProtKB/TrEMBL
  ENSCAFT00030021604.1 UniProtKB/TrEMBL
  ENSCAFT00040027147.1 UniProtKB/TrEMBL
  ENSCAFT00040027307.1 UniProtKB/TrEMBL
  ENSCAFT00040027341.1 UniProtKB/TrEMBL
  ENSCAFT00845032546.1 UniProtKB/TrEMBL
  ENSCAFT00845032944.1 UniProtKB/TrEMBL
  ENSCAFT00845033094 ENTREZGENE
  ENSCAFT00845033094.1 UniProtKB/TrEMBL
  ENSCAFT00845033244 ENTREZGENE
  ENSCAFT00845033244.1 UniProtKB/TrEMBL
  ENSCAFT00845033309.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1370.30 UniProtKB/TrEMBL
InterPro Peptidase_M2 UniProtKB/TrEMBL
NCBI Gene ACE ENTREZGENE
PANTHER ANGIOTENSIN-CONVERTING ENZYME UniProtKB/TrEMBL
  ANGIOTENSIN-CONVERTING ENZYME UniProtKB/TrEMBL
  ANGIOTENSIN-CONVERTING ENZYME-LIKE PROTEIN ACE3 UniProtKB/TrEMBL
  PTHR10514 UniProtKB/TrEMBL
Pfam Peptidase_M2 UniProtKB/TrEMBL
PRINTS PEPDIPTASEA UniProtKB/TrEMBL
PROSITE PEPTIDASE_M2 UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
UniProt A0A8C0N381_CANLF UniProtKB/TrEMBL
  A0A8C0RHV4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SLR7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SPL2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NX69_CANLF UniProtKB/TrEMBL
  A0A8I3NXF0_CANLF UniProtKB/TrEMBL
  A0A8I3P1U3_CANLF UniProtKB/TrEMBL
  A0A8I3S392_CANLF UniProtKB/TrEMBL
  A0A8I3S3I6_CANLF UniProtKB/TrEMBL
  A0A8P0NF47 ENTREZGENE
  A0A8P0NYQ5_CANLF UniProtKB/TrEMBL
  A0A8P0P2V5_CANLF UniProtKB/TrEMBL
  A0A8P0TQ57_CANLF UniProtKB/TrEMBL
  A0A8P0TSN0_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0NF47 UniProtKB/TrEMBL
VGNC ID VGNC:97183 ENTREZGENE