| 1351512 | XK | X-linked Kx blood group antigen, Kell and VPS13A binding protein | This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural ch aracteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008] | X | 37685791 | 37732130 | Human | 149 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1359650 | Xk | X-linked Kx blood group antigen, Kell and VPS13A binding protein | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); myelination (ortholog); ASSOCIATED WITH disease of mental health (ortholog); genetic disease (ortholog) ; hematopoietic system disease (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3-chloropropane-1,2-diol | X | 16108913 | 16145322 | Rat | 106 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1621581 | Xk | X-linked Kx blood group | Predicted to enable protein-macromolecule adaptor activity. Acts upstream of or within several processes, including intracellular monoatomic cation homeostasis; regulation of axon diameter; and skeletal muscle fiber development. Is active in plasma membrane. Is expressed in genitourinary system; gon adal fat pad; gut; liver; and mammary gland. Human ortholog(s) of this gene implicated in McLeod syndrome and hematopoietic system disease. Orthologous to human XK (X-linked Kx blood group antigen, Kell and VPS13A binding protein). [provided by Alliance of Genome Resources, Jul 2025] | X | 9139023 | 9179484 | Mouse | 122 | symbol , old_gene_name , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8836229 | Xk | X-linked Kx blood group antigen, Kell and VPS13A binding protein | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); myelination (ortholog); ASSOCIATED WITH disease of mental health (ortholog); genetic disease (ortholog) ; hematopoietic system disease (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); plasma membrane (ortholog) | NW_004955587 | 668871 | 725829 | Chinchilla | 22 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11948299 | XK | X-linked Kx blood group antigen, Kell and VPS13A binding protein | ENCODES a protein that exhibits protein-macromolecule adaptor activity (inferred); INVOLVED IN intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); myelination (ortholog); ASSOCIATED WITH disease of mental health (ortholog); genetic disease (ortholog) ; hematopoietic system disease (ortholog); FOUND IN plasma membrane (ortholog) | X | 30136046 | 30182541 | Bonobo | 26 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12244114 | XK | X-linked Kx blood group antigen, Kell and VPS13A binding protein | ENCODES a protein that exhibits protein-macromolecule adaptor activity (inferred); INVOLVED IN intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); myelination (ortholog); ASSOCIATED WITH disease of mental health (ortholog); genetic disease (ortholog) ; hematopoietic system disease (ortholog); FOUND IN plasma membrane (ortholog) | X | 32453404 | 32498145 | Dog | 28 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12444102 | Xk | X-linked Kx blood group antigen, Kell and VPS13A binding protein | ENCODES a protein that exhibits protein-macromolecule adaptor activity (inferred); INVOLVED IN intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); myelination (ortholog); ASSOCIATED WITH disease of mental health (ortholog); genetic disease (ortholog) ; hematopoietic system disease (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); plasma membrane (inferred) | NW_004936502 | 4532100 | 4584931 | Squirrel | 26 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14214844 | XK | X-linked Kx blood group antigen, Kell and VPS13A binding protein | ENCODES a protein that exhibits protein-macromolecule adaptor activity (inferred); INVOLVED IN intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); myelination (ortholog); ASSOCIATED WITH disease of mental health (ortholog); genetic disease (ortholog) ; hematopoietic system disease (ortholog); FOUND IN plasma membrane (ortholog) | | | | Pig | 28 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18478732 | XK | X-linked Kx blood group antigen, Kell and VPS13A binding protein | ENCODES a protein that exhibits protein-macromolecule adaptor activity (inferred); INVOLVED IN intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); myelination (ortholog); ASSOCIATED WITH disease of mental health (ortholog); genetic disease (ortholog) ; hematopoietic system disease (ortholog); FOUND IN plasma membrane (ortholog) | | | | Green Monkey | 26 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18912187 | Xk | X-linked Kx blood group antigen, Kell and VPS13A binding protein | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); myelination (ortholog); ASSOCIATED WITH disease of mental health (ortholog); genetic disease (ortholog) ; hematopoietic system disease (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 25 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155245016 | xk | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626011454 | Xk | X-linked Kx blood group antigen, Kell and VPS13A binding protein | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); INVOLVED IN intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); myelination (ortholog); ASSOCIATED WITH disease of mental health (ortholog); genetic disease (ortholog) ; hematopoietic system disease (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); plasma membrane (ortholog) | | | | Black Rat | 22 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155258743 | xk.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155245017 | xk.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934155 | xk.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934305 | xk.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934689 | xk.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934990 | xk.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1602431 | XKR3 | XK related 3 | XKRX (MIM 300684) and XKR3 are homologs of the Kell blood group precursor XK (MIM 314850), which is a putative membrane transporter and a component of the XK XK/Kell complex of the Kell blood group system (Calenda et al., 2006 [PubMed 16431037]).[supplied by OMIM, Mar 2008] | 22 | 16783480 | 16825411 | Human | 13 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 329346834 | XKR3 | XK related 3 | FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Bonobo | 5 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1549780 | Xkr4 | XK related 4 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN phosphatidylserine exposure on apoptotic cell surface (ortholog); ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN plasma membrane (ortholog); INTERAC TS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 5 | 20694433 | 21095350 | Rat | 68 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1606184 | XKR4 | XK related 4 | Enables phospholipid scramblase activity. Involved in phosphatidylserine exposure on apoptotic cell surface. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 8 | 55102028 | 55542054 | Human | 63 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8982872 | Xkr4 | XK related 4 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); INVOLVED IN phosphatidylserine exposure on apoptotic cell surface (ortholog); ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN plasma membrane (ortholog) | NW_004955454 | 14311466 | 14704334 | Chinchilla | 5 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12003129 | XKR4 | XK related 4 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); INVOLVED IN apoptotic process involved in development (inferred); engulfment of apoptotic cell (inferred); phosphatidylserine exposure on apoptotic cell surface (inferred); ASSOCIATED WITH substance-related disorder (orthol og); FOUND IN membrane (inferred); plasma membrane (inferred) | 8 | 51541410 | 51982587 | Bonobo | 13 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12136241 | XKR4 | XK related 4 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 29 | 6640108 | 7081182 | Dog | 12 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12718650 | Xkr4 | XK related 4 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); INVOLVED IN apoptotic process involved in development (inferred); engulfment of apoptotic cell (inferred); phosphatidylserine exposure on apoptotic cell surface (inferred); ASSOCIATED WITH substance-related disorder (orthol og); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936496 | 1887943 | 2289928 | Squirrel | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14280971 | XKR4 | XK related 4 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 12 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18762463 | XKR4 | XK related 4 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); INVOLVED IN phosphatidylserine exposure on apoptotic cell surface (ortholog); ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN plasma membrane (ortholog) | | | | Green Monkey | 5 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18911903 | Xkr4 | XK related 4 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); INVOLVED IN apoptotic process involved in development (inferred); engulfment of apoptotic cell (inferred); phosphatidylserine exposure on apoptotic cell surface (inferred); ASSOCIATED WITH substance-related disorder (orthol og); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 13 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626029631 | Xkr4 | XK related 4 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); INVOLVED IN phosphatidylserine exposure on apoptotic cell surface (ortholog); ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN plasma membrane (ortholog) | | | | Black Rat | 5 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1359335 | Xkr5 | XK related 5 | FOUND IN plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 77577387 | 77595377 | Rat | 65 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1604445 | XKR5 | XK related 5 | Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 8 | 6808517 | 6835524 | Human | 66 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8787019 | Xkr5 | XK related 5 | FOUND IN plasma membrane (ortholog) | NW_004955403 | 53964767 | 53981549 | Chinchilla | 1 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11986407 | XKR5 | XK related 5 | FOUND IN membrane (inferred); plasma membrane (inferred) | 8 | 445644 | 472659 | Bonobo | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12276668 | XKR5 | XK related 5 | FOUND IN plasma membrane (ortholog) | 16 | 58836581 | 58861698 | Dog | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12634874 | Xkr5 | XK related 5 | FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936615 | 4734805 | 4753194 | Squirrel | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13986099 | XKR5 | XK related 5 | FOUND IN plasma membrane (ortholog) | | | | Pig | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18421511 | XKR5 | XK related 5 | FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18914427 | Xkr5 | XK related 5 | FOUND IN plasma membrane (ortholog) | | | | Naked Mole-Rat | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626045401 | Xkr5 | XK related 5 | FOUND IN plasma membrane (ortholog) | | | | Black Rat | 1 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1310719 | Xkr6 | XK related 6 | FOUND IN plasma membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amitrole | 15 | 42032411 | 42269300 | Rat | 58 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1321790 | XKR6 | XK related 6 | Predicted to be involved in apoptotic process involved in development; engulfment of apoptotic cell; and phosphatidylserine exposure on apoptotic cell surface. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 8 | 10896045 | 11201833 | Human | 57 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8947861 | Xkr6 | XK related 6 | FOUND IN plasma membrane (ortholog) | NW_004955403 | 52410318 | 52636952 | Chinchilla | 1 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11884461 | XKR6 | XK related 6 | FOUND IN plasma membrane (ortholog) | 8 | 8000361 | 8310459 | Bonobo | 1 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12636049 | Xkr6 | XK related 6 | INVOLVED IN apoptotic process involved in development (inferred); engulfment of apoptotic cell (inferred); phosphatidylserine exposure on apoptotic cell surface (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936675 | 2750401 | 2768457 | Squirrel | 11 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14163015 | XKR6 | XK related 6 | FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 10 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18621530 | XKR6 | XK related 6 | FOUND IN plasma membrane (ortholog) | | | | Green Monkey | 1 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18921496 | Xkr6 | XK related 6 | INVOLVED IN apoptotic process involved in development (inferred); engulfment of apoptotic cell (inferred); phosphatidylserine exposure on apoptotic cell surface (inferred); FOUND IN plasma membrane (ortholog) | | | | Naked Mole-Rat | 11 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 20867324 | XKR6 | XK related 6 | INVOLVED IN apoptotic process involved in development (inferred); engulfment of apoptotic cell (inferred); phosphatidylserine exposure on apoptotic cell surface (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 11 | symbol , name | gene, protein-coding |
| 150657779 | XKR6 | XK related 6 | FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Dog | 10 | symbol , name | gene, protein-coding |
| 625880681 | Xkr6 | XK related 6 | FOUND IN plasma membrane (ortholog) | | | | Black Rat | 1 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1359224 | Xkr7 | XK related 7 | FOUND IN plasma membrane (ortholog); INTERACTS WITH bisphenol A; trichloroethene; 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ortholog) | 3 | 161960866 | 161985309 | Rat | 33 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1605535 | XKR7 | XK related 7 | Predicted to be involved in apoptotic process involved in development; engulfment of apoptotic cell; and phosphatidylserine exposure on apoptotic cell surface. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 20 | 31968151 | 32003387 | Human | 34 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8989057 | Xkr7 | XK related 7 | FOUND IN plasma membrane (ortholog) | NW_004955422 | 29015901 | 29024414 | Chinchilla | 2 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11865094 | XKR7 | XK related 7 | INVOLVED IN apoptotic process involved in development (inferred); engulfment of apoptotic cell (inferred); phosphatidylserine exposure on apoptotic cell surface (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | 20 | 28263026 | 28297736 | Bonobo | 12 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12050495 | XKR7 | XK related 7 | FOUND IN membrane (inferred); plasma membrane (inferred) | 24 | 21403557 | 21432207 | Dog | 11 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12584168 | Xkr7 | XK related 7 | INVOLVED IN apoptotic process involved in development (inferred); engulfment of apoptotic cell (inferred); phosphatidylserine exposure on apoptotic cell surface (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936485 | 18907218 | 18935306 | Squirrel | 12 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14031504 | XKR7 | XK related 7 | FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 11 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18627965 | XKR7 | XK related 7 | INVOLVED IN apoptotic process involved in development (inferred); engulfment of apoptotic cell (inferred); phosphatidylserine exposure on apoptotic cell surface (inferred); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 12 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18902942 | Xkr7 | XK related 7 | INVOLVED IN apoptotic process involved in development (inferred); engulfment of apoptotic cell (inferred); phosphatidylserine exposure on apoptotic cell surface (inferred); FOUND IN plasma membrane (ortholog) | | | | Naked Mole-Rat | 12 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 39131560 | XKR7 | XK related 7 | | | | | Chinchilla | | symbol , name | gene, protein-coding |
| 626016696 | Xkr7 | XK related 7 | FOUND IN plasma membrane (ortholog) | | | | Black Rat | 2 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1305649 | Xkr8 | XK related 8 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); INVOLVED IN engulfment of apoptotic cell (ortholog); neutrophil clearance (ortholog); phosphatidylserine exposure on apoptotic cell surface (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 5 | 150222058 | 150229184 | Rat | 86 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1602706 | XKR8 | XK related 8 | Enables phospholipid scramblase activity. Involved in engulfment of apoptotic cell; phosphatidylserine exposure on apoptotic cell surface; and positive regulation of myoblast differentiation. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 27959973 | 27968093 | Human | 79 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8920562 | Xkr8 | XK related 8 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); INVOLVED IN engulfment of apoptotic cell (ortholog); neutrophil clearance (ortholog); phosphatidylserine exposure on apoptotic cell surface (ortholog); FOUND IN plasma membrane (ortholog) | NW_004955452 | 7141088 | 7148571 | Chinchilla | 12 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12009076 | XKR8 | XK related 8 | ENCODES a protein that exhibits phospholipid scramblase activity (inferred); INVOLVED IN phosphatidylserine exposure on apoptotic cell surface (ortholog); tolerance induction to self antigen (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 1 | 27219682 | 27228381 | Bonobo | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12121843 | XKR8 | XK related 8 | ENCODES a protein that exhibits phospholipid scramblase activity (inferred); INVOLVED IN phosphatidylserine exposure on apoptotic cell surface (ortholog); tolerance induction to self antigen (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | 2 | 72419950 | 72426315 | Dog | 20 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12656138 | Xkr8 | XK related 8 | ENCODES a protein that exhibits phospholipid scramblase activity (inferred); INVOLVED IN phosphatidylserine exposure on apoptotic cell surface (ortholog); tolerance induction to self antigen (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936474 | 12180741 | 12187904 | Squirrel | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13862986 | XKR8 | XK related 8 | ENCODES a protein that exhibits phospholipid scramblase activity (inferred); INVOLVED IN phosphatidylserine exposure on apoptotic cell surface (ortholog); tolerance induction to self antigen (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 20 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18343945 | XKR8 | XK related 8 | ENCODES a protein that exhibits phospholipid scramblase activity (inferred); INVOLVED IN phosphatidylserine exposure on apoptotic cell surface (ortholog); tolerance induction to self antigen (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18911135 | Xkr8 | XK related 8 | ENCODES a protein that exhibits phospholipid scramblase activity (inferred); INVOLVED IN phosphatidylserine exposure on apoptotic cell surface (ortholog); tolerance induction to self antigen (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 21 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626099762 | Xkr8 | XK related 8 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); INVOLVED IN engulfment of apoptotic cell (ortholog); neutrophil clearance (ortholog); phosphatidylserine exposure on apoptotic cell surface (ortholog); FOUND IN plasma membrane (ortholog) | | | | Black Rat | 12 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1359260 | Xkr9 | XK related 9 | ENCODES a protein that exhibits phospholipid scramblase activity (ortholog); INVOLVED IN phosphatidylserine exposure on apoptotic cell surface (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 10316510 | 10345253 | Rat | 40 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1604439 | XKR9 | XK related 9 | Predicted to enable phospholipid scramblase activity. Predicted to be involved in phosphatidylserine exposure on apoptotic cell surface. Predicted to be located in plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Jul 2025] | 8 | 70669339 | 71065805 | Human | 40 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8718174 | Xkr9 | XK related 9 | FOUND IN plasma membrane (ortholog) | NW_004955444 | 9027662 | 9059911 | Chinchilla | 1 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11955381 | XKR9 | XK related 9 | FOUND IN membrane (inferred); plasma membrane (inferred) | 8 | 67194689 | 67259983 | Bonobo | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12252153 | XKR9 | XK related 9 | FOUND IN membrane (inferred); plasma membrane (inferred) | 29 | 19709517 | 19794811 | Dog | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12564380 | Xkr9 | XK related 9 | FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936648 | 1607 | 5784 | Squirrel | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14127406 | XKR9 | XK related 9 | FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18367795 | XKR9 | XK related 9 | FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 7 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625984073 | Xkr9 | XK related 9 | FOUND IN plasma membrane (ortholog) | | | | Black Rat | 1 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 1345703 | XKRX | XK related X-linked | This gene encodes a protein that is related to a component of the XK/Kell complex of the Kell blood group system. The encoded protein includes several transmembrane domains, is known to be exposed to the cell surface, and may function as a membrane transporter. [provided by RefSeq, May 2010] | X | 100886916 | 100959343 | Human | 58 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 9061084 | Xkrx | XK related X-linked | | NW_004955503 | 7037200 | 7066070 | Chinchilla | | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11720403 | XKRX | XK related X-linked | FOUND IN membrane (inferred); plasma membrane (inferred) | X | 90116066 | 90132075 | Bonobo | 4 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12249802 | XKRX | XK related X-linked | FOUND IN membrane (inferred); plasma membrane (inferred) | X | 74854947 | 74872918 | Dog | 4 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12499781 | Xkrx | XK related X-linked | FOUND IN membrane (inferred); plasma membrane (inferred) | NW_004936813 | 22094 | 34529 | Squirrel | 4 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14206024 | XKRX | XK related X-linked | FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Pig | 4 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18406222 | XKRX | XK related X-linked | FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 4 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18935128 | Xkrx | XK related X-linked | FOUND IN membrane (inferred); plasma membrane (inferred) | | | | Naked Mole-Rat | 4 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625873380 | Xkrx | XK related X-linked | | | | | Black Rat | | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11983967 | LOC100967633 | XK-related protein 3 | | 22 | 216516 | 241184 | Bonobo | | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12329630 | LOC486082 | XK-related protein 6 | FOUND IN plasma membrane (ortholog) | 25 | 26984638 | 27022933 | Dog | 1 | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1359223 | Xkrx | XK related, X-linked | FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH 3,7-dihydropurine-6-thione; acrylamide; alpha-Zearalanol | X | 101634438 | 101733814 | Rat | 56 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 11915735 | LOC100985236 | XK-related protein 8-like | | 7 | 5232775 | 5257276 | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 12078729 | LOC102151320 | XK-related protein 6-like | | 25 | 26716714 | 26809874 | Dog | | name | gene, protein-coding, MODEL [RefSeq] |
| 13980005 | LOC110257957 | XK-related protein 3-like | | | | | Pig | | name | gene, pseudo, MODEL [RefSeq] |
| 38508925 | AC092032.3 | XK related 8 (XKR8) pseudogene | | | | | Human | | name | gene, transcribed_unprocessed_pseudogene |
| 1344352 | XKRY | XK related, Y-linked (pseudogene) | This probable pseudogene is located in the nonrecombining portion of the Y chromosome, and is expressed specifically in testis. It is similar to the XK (X-linked Kell blood group precursor) gene, which encodes a putative membrane transport protein. This gene is present as two identical copies within a palindromic region; this record represents the more centromeric copy. [provided by RefSeq, Nov 2020] | Y | 17768980 | 17770560 | Human | 7 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map , old_gene_symbol | gene, pseudo, REVIEWED [RefSeq] |
| 1604932 | XKRYP1 | XK related, Y-linked pseudogene 1 | | Y | 18507812 | 18509608 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1604931 | XKRYP2 | XK related, Y-linked pseudogene 2 | | Y | 18810798 | 18812594 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1604930 | XKRYP3 | XK related, Y-linked pseudogene 3 | | Y | 23715687 | 23717485 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1604929 | XKRYP4 | XK related, Y-linked pseudogene 4 | | Y | 23916696 | 23918494 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1604928 | XKRYP5 | XK related, Y-linked pseudogene 5 | | Y | 25751617 | 25753415 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1604927 | XKRYP6 | XK related, Y-linked pseudogene 6 | | Y | 25952590 | 25954387 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1353485 | XKRYP7 | XK related, Y-linked pseudogene 7 | This probable pseudogene is located in the nonrecombining portion of the Y chromosome, and is expressed specifically in testis. It is similar to the XK (X-linked Kell blood group precursor) gene, which encodes a putative membrane transport protein. This gene is present as two identical copies within a palindromic region; this record represents the more telomeric copy. [provided by RefSeq, Nov 2020] | Y | 18135449 | 18137029 | Human | 2 | symbol , old_gene_name , COSMIC , name , description , Human Proteome Map , old_gene_symbol | gene, pseudo, REVIEWED [RefSeq] |
| 16568584 | PLA2G10KP | phospholipase A2 group XK, pseudogene | | | | | Human | | name | gene, unprocessed_pseudogene |
| 155782956 | PLA2G10KP | phospholipase A2 group XK, pseudogene | | 16 | 28773824 | 28777534 | Human | | name | gene, pseudo, INFERRED [RefSeq] |
| 329344799 | LOC129395552 | testis-specific XK-related protein, Y-linked-like | | | | | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 329332010 | LOC129395593 | testis-specific XK-related protein, Y-linked-like | | | | | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 329332050 | LOC129395597 | testis-specific XK-related protein, Y-linked-like | | | | | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 329330309 | LOC129395678 | testis-specific XK-related protein, Y-linked-like | | | | | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 329330729 | LOC129395682 | testis-specific XK-related protein, Y-linked-like | | | | | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 1620359 | Xkr4 | X-linked Kx blood group related 4 | Enables phospholipid scramblase activity and protein homodimerization activity. Involved in phosphatidylserine exposure on apoptotic cell surface. Located in plasma membrane. Orthologous to human XKR4 (XK related 4). [provid ed by Alliance of Genome Resources, Jul 2025] | 1 | 3269956 | 3741733 | Mouse | 66 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1615568 | Xkr5 | X-linked Kx blood group related 5 | Is active in plasma membrane. Orthologous to human XKR5 (XK related 5). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 18974172 | 19001126 | Mouse | 66 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1321791 | Xkr6 | X-linked Kx blood group related 6 | Predicted to be involved in apoptotic process involved in development; engulfment of apoptotic cell; and phosphatidylserine exposure on apoptotic cell surface. Is active in plasma membrane. Is expressed in nervous system. Orthologous to human XKR6 (XK font-weight:700;'>XK related 6). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 63841608 | 64084451 | Mouse | 55 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1614170 | Xkr7 | X-linked Kx blood group related 7 | Predicted to be involved in apoptotic process involved in development; engulfment of apoptotic cell; and phosphatidylserine exposure on apoptotic cell surface. Is active in plasma membrane. Orthologous to human XKR7 (XK rela ted 7). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 152873772 | 152902214 | Mouse | 34 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1313802 | Xkr8 | X-linked Kx blood group related 8 | Enables phospholipid scramblase activity. Involved in apoptotic cell clearance; phosphatidylserine exposure on apoptotic cell surface; and positive regulation of myoblast differentiation. Acts upstream of or within establishment of localization in cell and tolerance induction to self antigen. Is act ive in plasma membrane. Orthologous to human XKR8 (XK related 8). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 132452212 | 132459916 | Mouse | 93 | symbol , old_gene_name , PhenoGen , description , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1621192 | Xkr9 | X-linked Kx blood group related 9 | Enables phospholipid scramblase activity. Involved in phosphatidylserine exposure on apoptotic cell surface. Located in plasma membrane. Is expressed in midgut. Orthologous to human XKR9 (XK related 9). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 13738962 | 13772454 | Mouse | 36 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1623695 | Xkrx | X-linked Kx blood group related, X-linked | Predicted to be located in plasma membrane. Orthologous to human XKRX (XK related X-linked). [provided by Alliance of Genome Resources, Jul 2025] | X | 133049786 | 133086747 | Mouse | 60 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 39130791 | Gm57489 | predicted gene, 57489 | | 1 | 3741733 | 3742701 | Mouse | | old_gene_name | gene, pseudo, MODEL [RefSeq] |
| 15567505 | Gm52997 | predicted gene, 52997 | | | | | Mouse | | old_gene_name | gene, processed_pseudogene |
| 155246328 | xkr4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155250131 | xkr5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155236156 | xkr6 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155238026 | xkr7 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155235654 | xkr8 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155244750 | xkr9 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155260237 | xkrx | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14379458 | XKS1 | | | | | | Yeast | | symbol | gene, null |
| 155240208 | xkr4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155257962 | xkr4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155254613 | xkr5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155247283 | xkr6.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596933449 | xkr6.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934818 | xkr6.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596935590 | xkr6.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596935612 | xkr6.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155236157 | xkr6.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155259121 | xkr7.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155255722 | xkr7.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155255245 | xkr8.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155247896 | xkr9.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155240218 | xkr9.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626181994 | xkrx.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 16560204 | XKR4-AS1 | XKR4 antisense RNA 1 | | 8 | 55517187 | 55520978 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 734049 | COL1A1 | collagen type I alpha 1 chain | This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogen esis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008] | 17 | 50184101 | 50201631 | Human | 3028 | GenBank Protein | gene, protein-coding, REVIEWED [RefSeq] |
| 1323429 | PIDD1 | p53-induced death domain protein 1 | The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may functi on as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010] | 11 | 799184 | 809501 | Human | 201 | GenBank Protein | gene, protein-coding, REVIEWED [RefSeq] |
| 731598 | RHAG | Rh associated glycoprotein | The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrome.[provided by RefSeq, Mar 2009] | 6 | 49605175 | 49636839 | Human | 121 | GenBank Protein | gene, protein-coding, REVIEWED [RefSeq] |
| 1602274 | STING1 | stimulator of interferon response cGAMP interactor 1 | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon respons es. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014] | 5 | 139475533 | 139482758 | Human | 356 | GenBank Protein | gene, protein-coding, REVIEWED [RefSeq] |
| 1346715 | TLR9 | toll like receptor 9 | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen -associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017] | 3 | 52221080 | 52225645 | Human | 349 | GenBank Protein | gene, protein-coding, REVIEWED [RefSeq] |
| 1316929 | KEL | Kell metallo-endopeptidase (Kell blood group) | This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008] | 7 | 142941114 | 142962363 | Human | 81 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 18925617 | LOC101715668 | targeting protein for Xklp2-like | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18931593 | LOC101716387 | targeting protein for Xklp2-like | INVOLVED IN cell division (inferred); regulation of mitotic spindle organization (inferred); FOUND IN microtubule (inferred); nucleus (inferred); spindle (inferred) | | | | Naked Mole-Rat | 8 | name | gene, protein-coding, MODEL [RefSeq] |
| 8939204 | LOC102028449 | targeting protein for Xklp2-like | | NW_004955512 | 1984234 | 2025783 | Chinchilla | | name | gene, protein-coding, MODEL [RefSeq] |
| 626021275 | LOC116887995 | targeting protein for Xklp2-like | | | | | Black Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18936875 | LOC101707853 | targeting protein for Xklp2 pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 18912761 | LOC101721649 | targeting protein for Xklp2 pseudogene | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 8783453 | LOC102006463 | targeting protein for Xklp2 pseudogene | | NW_004955484 | 7904220 | 7935632 | Chinchilla | | name | gene, pseudo, MODEL [RefSeq] |
| 16568421 | AL031658.2 | novel transcript, sense intronic to XKR7 | | | | | Human | | name | gene, lncrna |
| 1311894 | Tpx2 | TPX2, microtubule nucleation factor | ENCODES a protein that exhibits importin-alpha family protein binding (ortholog); molecular adaptor activity (ortholog); protein kinase binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); microtubule nucleation (ortholog); mitotic spindle assembly (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN axon hillock (ortholog); intercellular bridge (ortholog); microtubule cytoskeleton (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 161778709 | 161820941 | Rat | 251 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1323589 | TPX2 | TPX2 microtubule nucleation factor | Enables importin-alpha family protein binding activity; molecular adaptor activity; and protein kinase binding activity. Involved in activation of protein kinase activity; microtubule cytoskeleton organization; and negative regulation of microtubule depolymerization. Located in intercellular bridge; nucleoplasm; and spindle. Is active in spindle. [provided by Alliance of Genome Resources, Apr 2025] | 20 | 31739290 | 31801800 | Human | 243 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1551918 | Tpx2 | TPX2, microtubule-associated | Enables importin-alpha family protein binding activity and protein kinase binding activity. Involved in mitotic spindle assembly and regulation of mitotic spindle organization. Located in axon hillock and spindle. Is expressed in cerebral cortex ventricular layer; large intestine; nephrogenic zone; and small intestine. Orthologous to human TPX2 (TPX2 microtubule nucleation factor). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 152689859 | 152737241 | Mouse | 274 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 8934727 | Tpx2 | TPX2 microtubule nucleation factor | ENCODES a protein that exhibits importin-alpha family protein binding (ortholog); molecular adaptor activity (ortholog); protein kinase binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); microtubule nucleation (ortholog); mitotic spindle assembly (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN axon hillock (ortholog); intercellular bridge (ortholog); microtubule cytoskeleton (ortholog) | NW_004955422 | 29170695 | 29233924 | Chinchilla | 30 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11691907 | TPX2 | TPX2 microtubule nucleation factor | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); molecular adaptor activity (inferred); protein kinase binding (inferred); INVOLVED IN activation of protein kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN axon hillock (inferred); intercellular bridge (inferred); microtubule (inferred) | 20 | 28032663 | 28095223 | Bonobo | 34 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12392684 | TPX2 | TPX2 microtubule nucleation factor | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); molecular adaptor activity (inferred); protein kinase binding (inferred); INVOLVED IN activation of protein kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN axon hillock (inferred); intercellular bridge (inferred); microtubule (inferred) | 24 | 21209494 | 21273029 | Dog | 38 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12531578 | Tpx2 | TPX2 microtubule nucleation factor | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); molecular adaptor activity (inferred); protein kinase binding (inferred); INVOLVED IN activation of protein kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN axon hillock (inferred); intercellular bridge (inferred); microtubule (inferred) | NW_004936485 | 18718801 | 18773315 | Squirrel | 34 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14176791 | TPX2 | TPX2 microtubule nucleation factor | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); molecular adaptor activity (inferred); protein kinase binding (inferred); INVOLVED IN activation of protein kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN axon hillock (inferred); intercellular bridge (inferred); microtubule (inferred); INTERACTS WITH deoxynivalenol; resveratrol | | | | Pig | 40 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18482053 | TPX2 | TPX2 microtubule nucleation factor | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); molecular adaptor activity (inferred); protein kinase binding (inferred); INVOLVED IN activation of protein kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN axon hillock (inferred); intercellular bridge (inferred); microtubule (inferred) | | | | Green Monkey | 34 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18913213 | Tpx2 | TPX2 microtubule nucleation factor | ENCODES a protein that exhibits importin-alpha family protein binding (inferred); molecular adaptor activity (inferred); protein kinase binding (inferred); INVOLVED IN activation of protein kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN axon hillock (inferred); intercellular bridge (inferred); microtubule (inferred) | | | | Naked Mole-Rat | 35 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 625835695 | Tpx2 | TPX2 microtubule nucleation factor | ENCODES a protein that exhibits importin-alpha family protein binding (ortholog); molecular adaptor activity (ortholog); protein kinase binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); microtubule nucleation (ortholog); mitotic spindle assembly (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN axon hillock (ortholog); intercellular bridge (ortholog); microtubule cytoskeleton (ortholog) | | | | Black Rat | 30 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1347414 | SP2 | Sp2 transcription factor | This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008] | 17 | 47896236 | 47931731 | Human | 77 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1558393 | Sp2 | Sp2 transcription factor | This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. The protein can act as a transcriptional activator or repressor, depending on the promoter and cell type. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 11 | 96844158 | 96873785 | Mouse | 101 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 736995 | SP7 | Sp7 transcription factor | This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010] | 12 | 53326575 | 53344793 | Human | 339 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1591359 | Tpx2-ps1 | TPX2, microtubule nucleation factor, pseudogene 1 | | X | 89395533 | 89397818 | Rat | | old_gene_name | gene, pseudo, MODEL [RefSeq] |
