Xk (X-linked Kx blood group antigen, Kell and VPS13A binding protein) - Rat Genome Database

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Gene: Xk (X-linked Kx blood group antigen, Kell and VPS13A binding protein) Ictidomys tridecemlineatus
Analyze
Symbol: Xk
Name: X-linked Kx blood group antigen, Kell and VPS13A binding protein (Ensembl:X-linked Kx blood group)
RGD ID: 12444102
Description: ENCODES a protein that exhibits protein-macromolecule adaptor activity (inferred); INVOLVED IN intracellular calcium ion homeostasis (ortholog); intracellular magnesium ion homeostasis (ortholog); myelination (ortholog); ASSOCIATED WITH autistic disorder (ortholog); disease of mental health (ortholog); genetic disease (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: membrane transport protein XK; X-linked Kx blood group; X-linked Kx blood group (McLeod syndrome)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X24,691,389 - 24,745,510 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365024,532,100 - 4,587,439 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365024,532,100 - 4,584,931 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Xk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X24,691,389 - 24,745,510 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365024,532,100 - 4,587,439 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365024,532,100 - 4,584,931 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X37,685,791 - 37,732,130 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX37,685,791 - 37,732,130 (+)EnsemblGRCh38hg38GRCh38
GRCh37X37,545,044 - 37,591,383 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X37,430,052 - 37,476,322 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X37,301,324 - 37,347,594NCBI
CeleraX41,682,795 - 41,729,061 (+)NCBICelera
Cytogenetic MapXp21.1NCBI
HuRefX35,290,888 - 35,336,107 (+)NCBIHuRef
CHM1_1X37,576,264 - 37,622,522 (+)NCBICHM1_1
T2T-CHM13v2.0X37,089,348 - 37,135,703 (+)NCBIT2T-CHM13v2.0
Xk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X9,139,023 - 9,179,484 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX9,138,995 - 9,179,489 (+)EnsemblGRCm39 Ensembl
GRCm38X9,272,784 - 9,313,245 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX9,272,756 - 9,313,250 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X8,849,910 - 8,890,371 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X8,429,873 - 8,468,132 (+)NCBIMGSCv36mm8
CeleraX7,012,285 - 7,052,336 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX4.22NCBI
Xk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X16,108,913 - 16,145,322 (-)NCBIGRCr8
mRatBN7.2X13,436,412 - 13,472,830 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX13,436,418 - 13,472,830 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX13,623,720 - 13,660,104 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X17,120,655 - 17,157,035 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X13,377,235 - 13,413,615 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X14,497,376 - 14,534,479 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX14,498,119 - 14,534,473 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X15,278,669 - 15,315,169 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X25,591,152 - 25,624,913 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X25,644,621 - 25,678,382 (-)NCBI
CeleraX13,951,523 - 13,985,552 (+)NCBICelera
Cytogenetic MapXq12NCBI
Xk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955587668,070 - 728,959 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955587668,871 - 725,829 (+)NCBIChiLan1.0ChiLan1.0
XK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X39,334,500 - 39,381,063 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X39,337,936 - 39,384,437 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X30,136,046 - 30,182,541 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X37,846,539 - 37,892,348 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX37,846,539 - 37,892,348 (+)Ensemblpanpan1.1panPan2
XK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X32,453,404 - 32,498,145 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX32,453,570 - 32,495,110 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX19,801,126 - 19,845,752 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X32,491,214 - 32,543,437 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX32,491,295 - 32,540,402 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X32,578,961 - 32,624,840 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X32,544,040 - 32,588,642 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X32,592,018 - 32,636,881 (+)NCBIUU_Cfam_GSD_1.0
XK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX33,544,731 - 33,602,574 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X33,544,287 - 33,602,576 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X37,205,690 - 37,263,628 (+)NCBISscrofa10.2Sscrofa10.2susScr3
XK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366605638,148,973 - 38,193,937 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Xk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476217,856,731 - 17,914,938 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476217,856,746 - 17,915,975 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000024849   ⟹   ENSSTOP00000018994
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365024,532,100 - 4,587,439 (+)Ensembl
RefSeq Acc Id: XM_005323954   ⟹   XP_005324011
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X24,691,389 - 24,745,510 (+)NCBI
SpeTri2.0NW_0049365024,532,100 - 4,584,931 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040273247   ⟹   XP_040129181
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X24,691,395 - 24,745,510 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005324011 (Get FASTA)   NCBI Sequence Viewer  
  XP_040129181 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000018994.1
GenBank Protein KAG3271927 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005324011   ⟸   XM_005323954
- Peptide Label: isoform X1
- UniProtKB: I3N3P8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040129181   ⟸   XM_040273247
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000018994   ⟸   ENSSTOT00000024849


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000021262 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024849.2 UniProtKB/TrEMBL
InterPro XK-rel UniProtKB/TrEMBL
NCBI Gene Xk ENTREZGENE
PANTHER MEMBRANE TRANSPORT PROTEIN XK UniProtKB/TrEMBL
  MEMBRANE TRANSPORT PROTEIN XK FAMILY MEMBER UniProtKB/TrEMBL
Pfam XK-related UniProtKB/TrEMBL
UniProt I3N3P8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-19 Xk  X-linked Kx blood group antigen, Kell and VPS13A binding protein  Xk  X-linked Kx blood group  Symbol and/or name change 5135510 APPROVED