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70 records found for search term Il18
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
2889Il18interleukin 18ENCODES a protein that exhibits cytokine activity (ortholog); interleukin-18 receptor binding (ortholog); receptor ligand activity (ortholog); INVOLVED IN cellular response to cAMP; cellular response to hydrogen peroxide; cellular response to lipopolysaccharide; PARTICIPATES IN interleukin-12 signal85980207259829275Rat1138symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
730894IL18interleukin 18The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable 11112143260112164094Human1129symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
730895Il18interleukin 18Enables cytokine activity. Involved in several processes, including cholesterol homeostasis; establishment of skin barrier; and positive regulation of cell differentiation. Acts upstream of or within several processes, including natural killer cell mediated cytotoxicity; negative regulation of myobl95046600050493141Mouse1196symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8816121Il18interleukin 18ENCODES a protein that exhibits cytokine activity (ortholog); interleukin-18 receptor binding (ortholog); receptor ligand activity (ortholog); INVOLVED IN angiogenesis (ortholog); cell population proliferation (ortholog); cellular response to cAMP (ortholog); PARTICIPATES IN interleukin-12 signalingNW_0049554121380736113826007Chinchilla338symbolgene, protein-coding, MODEL [RefSeq]
11700614IL18interleukin 18ENCODES a protein that exhibits cytokine activity (inferred); interleukin-18 receptor binding (inferred); receptor ligand activity (inferred); INVOLVED IN cell population proliferation (ortholog); cellular response to cAMP (ortholog); cellular response to hydrogen peroxide (ortholog); PARTICIPATES I11107024376107045194Bonobo347symbolgene, protein-coding, MODEL [RefSeq]
12116574IL18interleukin 18ENCODES a protein that exhibits cytokine activity (ortholog); interleukin-18 receptor binding (ortholog); INVOLVED IN extrinsic apoptotic signaling pathway via death domain receptors; positive regulation of type II interferon production; cell population proliferation (ortholog); PARTICIPATES IN inte52097274220995327Dog358symbolgene, protein-coding, PROVISIONAL [RefSeq]
12448428Il18interleukin 18ENCODES a protein that exhibits cytokine activity (inferred); interleukin-18 receptor binding (inferred); receptor ligand activity (inferred); INVOLVED IN cell population proliferation (ortholog); cellular response to cAMP (ortholog); cellular response to hydrogen peroxide (ortholog); PARTICIPATES INW_00493661223069632325086Squirrel345symbolgene, protein-coding, MODEL [RefSeq]
14201393IL18interleukin 18ENCODES a protein that exhibits cytokine activity; interleukin-18 receptor binding (ortholog); INVOLVED IN extrinsic apoptotic signaling pathway via death domain receptors; positive regulation of cell population proliferation; positive regulation of type II interferon production; PARTICIPATES IN intPig375symbolgene, protein-coding, PROVISIONAL [RefSeq]
18741146IL18interleukin 18ENCODES a protein that exhibits cytokine activity (inferred); interleukin-18 receptor binding (inferred); receptor ligand activity (inferred); INVOLVED IN cell population proliferation (ortholog); cellular response to cAMP (ortholog); cellular response to hydrogen peroxide (ortholog); PARTICIPATES IGreen Monkey347symbolgene, protein-coding, MODEL [RefSeq]
18920996Il18interleukin 18ENCODES a protein that exhibits cytokine activity (inferred); interleukin-18 receptor binding (inferred); receptor ligand activity (inferred); INVOLVED IN cell population proliferation (ortholog); cellular response to cAMP (ortholog); cellular response to hydrogen peroxide (ortholog); PARTICIPATES INaked Mole-Rat345symbolgene, protein-coding, MODEL [RefSeq]
288083485il18Tropical Clawed Frogsymbolgene, null
405857356il18Tropical Clawed Frogsymbolgene, null
405860290il18Tropical Clawed Frogsymbolgene, null
405861400il18Tropical Clawed Frogsymbolgene, null
405863855il18Tropical Clawed Frogsymbolgene, null
598276823il18Tropical Clawed Frogsymbolgene, null
625874872Il18interleukin 18ENCODES a protein that exhibits cytokine activity (ortholog); interleukin-18 receptor binding (ortholog); receptor ligand activity (ortholog); INVOLVED IN angiogenesis (ortholog); cell population proliferation (ortholog); cellular response to cAMP (ortholog); PARTICIPATES IN interleukin-12 signalingBlack Rat338symbolgene, protein-coding, MODEL [RefSeq]
288057046il18.LAfrican Clawed Frogsymbolgene, null
405856014il18.LAfrican Clawed Frogsymbolgene, null
405861399il18.LAfrican Clawed Frogsymbolgene, null
405863856il18.LAfrican Clawed Frogsymbolgene, null
405864091il18.LAfrican Clawed Frogsymbolgene, null
626184374il18.LAfrican Clawed Frogsymbolgene, null
288083486il18.SAfrican Clawed Frogsymbolgene, null
405856999il18.SAfrican Clawed Frogsymbolgene, null
405857357il18.SAfrican Clawed Frogsymbolgene, null
405860289il18.SAfrican Clawed Frogsymbolgene, null
405863522il18.SAfrican Clawed Frogsymbolgene, null
626172633il18.SAfrican Clawed Frogsymbolgene, null
620042Il18bpinterleukin 18 binding proteinENCODES a protein that exhibits interleukin-18 binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide; cellular response to tumor necrosis factor; response to lipopolysaccharide; ASSOCIATED WITH Experimental Mammary Neoplasms; Liver Reperfusion Injury; Transplant Rejection; FOUND IN 1165784916165787990Rat97symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1348622IL18BPinterleukin 18 binding proteinThe protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18117199890972008200Human117symbol , COSMIC , description , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1551696Il18bpinterleukin 18 binding proteinPredicted to enable interleukin-18 binding activity. Predicted to be involved in T-helper 1 type immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in gut; liver; and male reproductive gland or organ. Human ortholog(s) of thi7101664281101669699Mouse124symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8750965Il18bpinterleukin 18 binding proteinENCODES a protein that exhibits interleukin-18 binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to tumor necrosis factor (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH alcoholic liver cirrhosis (ortholog); allergic contact dNW_0049554141932782819332577Chinchilla23symbolgene, protein-coding, MODEL [RefSeq]
11893802IL18BPinterleukin 18 binding proteinENCODES a protein that exhibits interleukin-18 binding (inferred); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to tumor necrosis factor (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH alcoholic liver cirrhosis (ortholog); allergic contact d116707825167083043Bonobo27symbolgene, protein-coding, MODEL [RefSeq]
12214637IL18BPinterleukin 18 binding proteinENCODES a protein that exhibits interleukin-18 binding (inferred); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to tumor necrosis factor (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH alcoholic liver cirrhosis (ortholog); allergic contact d212607651526080741Dog23symbolgene, protein-coding, PROVISIONAL [RefSeq]
12661436Il18bpinterleukin 18 binding proteinENCODES a protein that exhibits interleukin-18 binding (inferred); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to tumor necrosis factor (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH alcoholic liver cirrhosis (ortholog); allergic contact dNW_00493649813535691358312Squirrel27symbolgene, protein-coding, MODEL [RefSeq]
13910671IL18BPinterleukin 18 binding proteinENCODES a protein that exhibits interleukin-18 binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to tumor necrosis factor (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WIPig35symbolgene, protein-coding, MODEL [RefSeq]
18415857IL18BPinterleukin 18 binding proteinENCODES a protein that exhibits interleukin-18 binding (inferred); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to tumor necrosis factor (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH alcoholic liver cirrhosis (ortholog); allergic contact dGreen Monkey27symbolgene, protein-coding, MODEL [RefSeq]
18929187Il18bpinterleukin 18 binding proteinENCODES a protein that exhibits interleukin-18 binding (inferred); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to tumor necrosis factor (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH alcoholic liver cirrhosis (ortholog); allergic contact dNaked Mole-Rat25symbolgene, protein-coding, MODEL [RefSeq]
625992963Il18bpinterleukin 18 binding proteinENCODES a protein that exhibits interleukin-18 binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide (ortholog); cellular response to tumor necrosis factor (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH alcoholic liver cirrhosis (ortholog); allergic contact dBlack Rat23symbolgene, protein-coding, MODEL [RefSeq]
626468158il18bpTropical Clawed Frogsymbolgene, null
626468515il18bpTropical Clawed Frogsymbolgene, null
1308589Il18r1interleukin 18 receptor 1ENCODES a protein that exhibits interleukin-18 binding (ortholog); interleukin-18 receptor activity (ortholog); INVOLVED IN interleukin-18-mediated signaling pathway (ortholog); natural killer cell activation (ortholog); negative regulation of cold-induced thermogenesis (ortholog); PARTICIPATES IN i95022327450257370Rat151symbol , old_gene_name , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1318449IL18R1interleukin 18 receptor 1The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-a2102355796102398776Human155symbol , old_gene_name , COSMIC , description , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1318450Il18r1interleukin 18 receptor 1Enables interleukin-18 receptor activity. Involved in negative regulation of cold-induced thermogenesis and positive regulation of non-canonical NF-kappaB signal transduction. Acts upstream of or within several processes, including T-helper 1 cell differentiation; interleukin-18-mediated signaling p14050471240540014Mouse157symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
8924667Il18r1interleukin 18 receptor 1ENCODES a protein that exhibits interleukin-18 binding (ortholog); interleukin-18 receptor activity (ortholog); INVOLVED IN interleukin-18-mediated signaling pathway (ortholog); natural killer cell activation (ortholog); negative regulation of cold-induced thermogenesis (ortholog); PARTICIPATES IN iNW_00495547078549957887810Chinchilla33symbolgene, protein-coding, MODEL [RefSeq]
11698160IL18R1interleukin 18 receptor 1ENCODES a protein that exhibits hydrolase activity (inferred); interleukin-18 binding (inferred); interleukin-18 receptor activity (inferred); INVOLVED IN interleukin-18-mediated signaling pathway (ortholog); natural killer cell activation (ortholog); positive regulation of T-helper 1 cell cytokine 2A9941968699462650Bonobo37symbolgene, protein-coding, MODEL [RefSeq]
12217575IL18R1interleukin 18 receptor 1ENCODES a protein that exhibits hydrolase activity (inferred); interleukin-1 receptor activity (inferred); interleukin-18 binding (inferred); INVOLVED IN interleukin-18-mediated signaling pathway (ortholog); natural killer cell activation (ortholog); positive regulation of type II interferon product104061433640653300Dog49symbolgene, protein-coding, MODEL [RefSeq]
12664203Il18r1interleukin 18 receptor 1ENCODES a protein that exhibits hydrolase activity (inferred); interleukin-18 binding (inferred); interleukin-18 receptor activity (inferred); INVOLVED IN interleukin-18-mediated signaling pathway (ortholog); natural killer cell activation (ortholog); positive regulation of type II interferon producNW_00493671310389851075770Squirrel42symbolgene, protein-coding, MODEL [RefSeq]
14266638IL18R1interleukin 18 receptor 1ENCODES a protein that exhibits hydrolase activity (inferred); interleukin-18 binding (inferred); interleukin-18 receptor activity (inferred); INVOLVED IN interleukin-18-mediated signaling pathway (ortholog); natural killer cell activation (ortholog); positive regulation of type II interferon producPig46symbolgene, protein-coding, PROVISIONAL [RefSeq]
18514844IL18R1interleukin 18 receptor 1ENCODES a protein that exhibits hydrolase activity (inferred); interleukin-18 binding (inferred); interleukin-18 receptor activity (inferred); INVOLVED IN interleukin-18-mediated signaling pathway (ortholog); natural killer cell activation (ortholog); positive regulation of type II interferon producGreen Monkey42symbolgene, protein-coding, MODEL [RefSeq]
18925990Il18r1interleukin 18 receptor 1ENCODES a protein that exhibits hydrolase activity (inferred); interleukin-1 receptor activity (inferred); interleukin-18 binding (inferred); INVOLVED IN interleukin-18-mediated signaling pathway (ortholog); natural killer cell activation (ortholog); negative regulation of cold-induced thermogenesisNaked Mole-Rat40symbolgene, protein-coding, MODEL [RefSeq]
625891556Il18r1interleukin 18 receptor 1ENCODES a protein that exhibits interleukin-18 binding (ortholog); interleukin-18 receptor activity (ortholog); INVOLVED IN interleukin-18-mediated signaling pathway (ortholog); natural killer cell activation (ortholog); negative regulation of cold-induced thermogenesis (ortholog); PARTICIPATES IN iBlack Rat33symbolgene, protein-coding, MODEL [RefSeq]
727867Il18rapinterleukin 18 receptor accessory proteinENCODES a protein that exhibits coreceptor activity (ortholog); interleukin-18 receptor activity (ortholog); INVOLVED IN cellular response to cytokine stimulus; cellular response to hydrogen peroxide; cell population proliferation (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interle95026372350296583Rat102symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1315691IL18RAPinterleukin 18 receptor accessory proteinThe protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding2102418621102452565Human111symbol , COSMIC , description , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1315692Il18rapinterleukin 18 receptor accessory proteinInterleukin-18 (or interferon-gamma inducing factor) is a proinflammatory cytokine that induces cell-mediated immunity following microbial infection. This gene encodes a member of the interleukin-1 receptor family. The encoded protein is an accessory subunit of the receptor for interleukin-18 and me14055454840590867Mouse116symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
9043370Il18rapinterleukin 18 receptor accessory proteinENCODES a protein that exhibits coreceptor activity (ortholog); interleukin-18 receptor activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to cytokine stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); PARTICIPATES IN interleukin-12 signNW_00495547078949007923653Chinchilla20symbolgene, protein-coding, MODEL [RefSeq]
11887446IL18RAPinterleukin 18 receptor accessory proteinENCODES a protein that exhibits coreceptor activity (inferred); hydrolase activity (inferred); interleukin-18 receptor activity (inferred); INVOLVED IN cell population proliferation (ortholog); cellular response to cytokine stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); PART2A9936382399393346Bonobo27symbolgene, protein-coding, MODEL [RefSeq]
12314798IL18RAPinterleukin 18 receptor accessory proteinENCODES a protein that exhibits coreceptor activity (inferred); hydrolase activity (inferred); interleukin-18 receptor activity (inferred); INVOLVED IN cell population proliferation (ortholog); cellular response to cytokine stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); PART104057850340605800Dog30symbolgene, protein-coding, MODEL [RefSeq]
12623844Il18rapinterleukin 18 receptor accessory proteinENCODES a protein that exhibits coreceptor activity (ortholog); interleukin-18 receptor activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to cytokine stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); PARTICIPATES IN interleukin-12 signNW_00493671310878841115512Squirrel20symbolgene, protein-coding, MODEL [RefSeq]
13939636IL18RAPinterleukin 18 receptor accessory proteinENCODES a protein that exhibits coreceptor activity (inferred); hydrolase activity (inferred); interleukin-18 receptor activity (inferred); INVOLVED IN cell population proliferation (ortholog); cellular response to cytokine stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); PARTPig29symbolgene, protein-coding, MODEL [RefSeq]
18764960IL18RAPinterleukin 18 receptor accessory proteinENCODES a protein that exhibits coreceptor activity (inferred); hydrolase activity (inferred); interleukin-18 receptor activity (inferred); INVOLVED IN cell population proliferation (ortholog); cellular response to cytokine stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); PARTGreen Monkey27symbolgene, protein-coding, MODEL [RefSeq]
18924155Il18rapinterleukin 18 receptor accessory proteinENCODES a protein that exhibits coreceptor activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to cytokine stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathwNaked Mole-Rat27symbolgene, protein-coding, MODEL [RefSeq]
284672088il18rapTropical Clawed Frogsymbolgene, null
626160416Il18rapinterleukin 18 receptor accessory proteinENCODES a protein that exhibits coreceptor activity (ortholog); interleukin-18 receptor activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to cytokine stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); PARTICIPATES IN interleukin-12 signBlack Rat20symbolgene, protein-coding, MODEL [RefSeq]
288072360il18r1.1Tropical Clawed Frogsymbolgene, null
284672414il18rap.LAfrican Clawed Frogsymbolgene, null
288072361il18r1.1.LAfrican Clawed Frogsymbolgene, null
1346334IL37interleukin 37The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL182112911165112918882Human96descriptiongene, protein-coding, REVIEWED [RefSeq]
1353187IL1RL2interleukin 1 receptor like 2The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor f2102186973102243086Human83descriptiongene, protein-coding, REVIEWED [RefSeq]