IL18RAP (interleukin 18 receptor accessory protein) - Rat Genome Database

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Gene: IL18RAP (interleukin 18 receptor accessory protein) Pan paniscus
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Symbol: IL18RAP
Name: interleukin 18 receptor accessory protein
RGD ID: 11887446
Description: ENCODES a protein that exhibits coreceptor activity (inferred); hydrolase activity (inferred); interleukin-18 receptor activity (inferred); INVOLVED IN cell population proliferation (ortholog); cellular response to cytokine stimulus (ortholog); cellular response to hydrogen peroxide (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; ASSOCIATED WITH aortic dissection (ortholog); Bronchial Hyperreactivity (ortholog); inflammatory bowel disease (ortholog); FOUND IN interleukin-18 receptor complex (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21225,250,507 - 25,280,305 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A25,253,272 - 25,283,070 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A99,363,823 - 99,393,346 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A103,510,109 - 103,543,950 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A103,510,109 - 103,544,916 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
IL18RAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21225,250,507 - 25,280,305 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A25,253,272 - 25,283,070 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A99,363,823 - 99,393,346 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A103,510,109 - 103,543,950 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A103,510,109 - 103,544,916 (+)Ensemblpanpan1.1panPan2
IL18RAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382102,418,621 - 102,452,565 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2102,418,689 - 102,452,565 (+)EnsemblGRCh38hg38GRCh38
GRCh372103,035,081 - 103,069,025 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362102,401,686 - 102,435,457 (+)NCBINCBI36Build 36hg18NCBI36
Build 342102,493,771 - 102,527,543NCBI
Celera297,236,395 - 97,270,167 (+)NCBICelera
Cytogenetic Map2q12.1NCBI
HuRef296,799,620 - 96,833,394 (+)NCBIHuRef
CHM1_12103,039,555 - 103,073,326 (+)NCBICHM1_1
T2T-CHM13v2.02102,877,486 - 102,911,541 (+)NCBIT2T-CHM13v2.0
Il18rap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39140,554,548 - 40,590,867 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl140,554,522 - 40,590,865 (+)EnsemblGRCm39 Ensembl
GRCm38140,515,362 - 40,551,707 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl140,515,362 - 40,551,705 (+)EnsemblGRCm38mm10GRCm38
MGSCv37140,572,207 - 40,606,148 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36140,459,909 - 40,493,851 (+)NCBIMGSCv36mm8
Celera140,327,551 - 40,361,507 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map119.37NCBI
Il18rap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8950,263,723 - 50,296,583 (+)NCBIGRCr8
mRatBN7.2942,768,112 - 42,800,964 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl942,768,220 - 42,800,959 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0947,225,543 - 47,255,805 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl947,225,585 - 47,258,503 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0946,909,764 - 46,940,139 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4939,676,026 - 39,677,475 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1939,677,439 - 39,678,889 (+)NCBI
Celera940,511,761 - 40,545,650 (+)NCBICelera
Cytogenetic Map9q22NCBI
Il18rap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554707,893,329 - 7,923,744 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554707,894,900 - 7,923,653 (+)NCBIChiLan1.0ChiLan1.0
IL18RAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11040,578,503 - 40,605,800 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1040,581,096 - 40,605,766 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1040,504,647 - 40,531,943 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01041,444,971 - 41,472,267 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1041,447,562 - 41,472,778 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11041,159,477 - 41,186,767 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01041,440,138 - 41,467,387 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01041,632,829 - 41,660,098 (-)NCBIUU_Cfam_GSD_1.0
Il18rap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629290,017,009 - 90,045,035 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049367131,087,884 - 1,115,512 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL18RAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl351,762,486 - 51,794,471 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1351,762,111 - 51,794,552 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2354,241,979 - 54,274,049 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL18RAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1146,081,539 - 6,114,412 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl146,085,262 - 6,114,028 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041173,763,307 - 173,797,307 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il18rap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247496,930,025 - 6,957,241 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034953653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000034991   ⟹   ENSPPAP00000012327
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A103,510,109 - 103,543,949 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000034996   ⟹   ENSPPAP00000012332
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A103,513,664 - 103,544,916 (+)Ensembl
RefSeq Acc Id: XM_034953653   ⟹   XP_034809544
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21225,250,507 - 25,280,305 (-)NCBI
NHGRI_mPanPan12A25,253,272 - 25,283,070 (-)NCBI
Mhudiblu_PPA_v02A99,363,823 - 99,393,346 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034809544 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000012327.1
  ENSPPAP00000012332.1
RefSeq Acc Id: XP_034809544   ⟸   XM_034953653
- UniProtKB: A0A2R9A4V6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000012332   ⟸   ENSPPAT00000034996
Ensembl Acc Id: ENSPPAP00000012327   ⟸   ENSPPAT00000034991
Protein Domains
Ig-like   TIR


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029352 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000034991.1 UniProtKB/TrEMBL
  ENSPPAT00000034996.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.40.50.10140 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  IL-1_rcpt_fam UniProtKB/TrEMBL
  IL-1RAcP-like_ig UniProtKB/TrEMBL
  TIR_dom UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/TrEMBL
NCBI Gene IL18RAP ENTREZGENE
PANTHER INTERLEUKIN-18 RECEPTOR ACCESSORY PROTEIN UniProtKB/TrEMBL
  PTHR11890 UniProtKB/TrEMBL
Pfam Ig_6 UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
PRINTS INTRLKN1R1F UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF52200 UniProtKB/TrEMBL
UniProt A0A2R9A4V6 ENTREZGENE, UniProtKB/TrEMBL