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51 records found for search term Hdc
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
2790Hdchistidine decarboxylaseENCODES a protein that exhibits amino acid binding; histidine decarboxylase activity; identical protein binding; INVOLVED IN amino acid metabolic process; histamine metabolic process; L-histidine metabolic process; PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; ASSOCIATED WITH rh3134300628134318704Rat269symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
10706Hdchistidine decarboxylaseEnables histidine decarboxylase activity. Acts upstream of or within L-histidine catabolic process and histamine biosynthetic process. Predicted to be located in dendrite and neuronal cell body. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; bra2126435579126465942Mouse289symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
736253HDChistidine decarboxylaseThis gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscl155024194750265726Human256symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
8830504Hdchistidine decarboxylaseENCODES a protein that exhibits amino acid binding (ortholog); histidine decarboxylase activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); histamine biosynthetic process (ortholog); histamine metabolic process (ortholog); PARTICIPATES IN hiNW_00495540940515744072641Chinchilla27symbolgene, protein-coding, MODEL [RefSeq]
11999973HDChistidine decarboxylaseENCODES a protein that exhibits amino acid binding (ortholog); histidine decarboxylase activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); histamine biosynthetic process (ortholog); histamine metabolic process (ortholog); PARTICIPATES IN hi152918829629212327Bonobo42symbolgene, protein-coding, MODEL [RefSeq]
12364211HDChistidine decarboxylaseENCODES a protein that exhibits amino acid binding (ortholog); histidine decarboxylase activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); histamine biosynthetic process (ortholog); histamine metabolic process (ortholog); PARTICIPATES IN hi301620122216223452Dog40symbolgene, protein-coding, MODEL [RefSeq]
12532910Hdchistidine decarboxylaseENCODES a protein that exhibits amino acid binding (ortholog); histidine decarboxylase activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); histamine biosynthetic process (ortholog); histamine metabolic process (ortholog); PARTICIPATES IN hiNW_0049364711230380212324613Squirrel41symbolgene, protein-coding, MODEL [RefSeq]
14054578HDChistidine decarboxylaseENCODES a protein that exhibits amino acid binding (ortholog); histidine decarboxylase activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); histamine biosynthetic process (ortholog); histamine metabolic process (ortholog); PARTICIPATES IN hiPig41symbolgene, protein-coding, MODEL [RefSeq]
14377766hdcFlysymbolgene, null
18455234HDChistidine decarboxylaseENCODES a protein that exhibits amino acid binding (ortholog); histidine decarboxylase activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); histamine biosynthetic process (ortholog); histamine metabolic process (ortholog); PARTICIPATES IN hiGreen Monkey42symbolgene, protein-coding, MODEL [RefSeq]
18915663Hdchistidine decarboxylaseENCODES a protein that exhibits amino acid binding (ortholog); histidine decarboxylase activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); histamine biosynthetic process (ortholog); histamine metabolic process (ortholog); PARTICIPATES IN hiNaked Mole-Rat41symbolgene, protein-coding, MODEL [RefSeq]
155243099hdcTropical Clawed Frogsymbolgene, null
626048499Hdchistidine decarboxylaseENCODES a protein that exhibits amino acid binding (ortholog); histidine decarboxylase activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); histamine biosynthetic process (ortholog); histamine metabolic process (ortholog); PARTICIPATES IN hiBlack Rat27symbolgene, protein-coding, MODEL [RefSeq]
155247408hdc.LAfrican Clawed Frogsymbolgene, null
405857811hdc.SAfrican Clawed Frogsymbolgene, null
405858479hdc.SAfrican Clawed Frogsymbolgene, null
405863042hdc.SAfrican Clawed Frogsymbolgene, null
405863880hdc.SAfrican Clawed Frogsymbolgene, null
626469367hdc.SAfrican Clawed Frogsymbolgene, null
1312483HECAhdc homolog, cell cycle regulatorThis gene encodes the homolog of the Drosophila headcase protein, a highly basic, cytoplasmic protein that regulates the re-entry of imaginal cells into the mitotic cycle during adult morphogenesis. In Drosophila, the encoded protein also inhibits terminal branching of neighboring cells during trach6139135080139180802Human84name , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1615528Hecahdc homolog, cell cycle regulatorPredicted to be involved in negative regulation of mitotic cell cycle. Predicted to be located in cytoplasm and nucleus. Orthologous to human HECA (hdc homolog, cell cycle regulator). [provided by Alliance of Genome Resources, Jul 2025]101777478817823785Mouse89name , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1320216CD209CD209 moleculeThis gene encodes a C-type lectin that functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including leprosy and tuberculosis mycobacteria, the Ebola, hepatitis C, HIV-1 and Dengue viru1977399937747534Human122old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1321334DCSTAMPdendrocyte expressed seven transmembrane proteinThis gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing r8104339796104356689Human94old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1304818Hecahdc homolog, cell cycle regulatorENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN negative regulation of mitotic cell cycle (ortholog); stress granule assembly (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-11434530614395226Rat87namegene, protein-coding, VALIDATED [RefSeq]
8836874Hecahdc homolog, cell cycle regulatorENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN negative regulation of mitotic cell cycle (ortholog); stress granule assembly (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); nucleus (ortholog)NW_0049554362052321520569403Chinchilla7namegene, protein-coding, MODEL [RefSeq]
12010504HECAhdc homolog, cell cycle regulatorENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN negative regulation of mitotic cell cycle (inferred); stress granule assembly (inferred); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); nucleus (inferred)6136898465136943055Bonobo6namegene, protein-coding, MODEL [RefSeq]
12295486HECAhdc homolog, cell cycle regulatorENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN negative regulation of mitotic cell cycle (inferred); stress granule assembly (inferred); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); nucleus (inferred)13133291531383688Dog6namegene, protein-coding, MODEL [RefSeq]
12562979Hecahdc homolog, cell cycle regulatorENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN negative regulation of mitotic cell cycle (inferred); stress granule assembly (inferred); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); nucleus (inferred)NW_00493656061654656210335Squirrel6namegene, protein-coding, MODEL [RefSeq]
14022494HECAhdc homolog, cell cycle regulatorENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN negative regulation of mitotic cell cycle (inferred); stress granule assembly (inferred); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); nucleus (inferred)Pig6namegene, protein-coding, MODEL [RefSeq]
18473092HECAhdc homolog, cell cycle regulatorENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN negative regulation of mitotic cell cycle (ortholog); stress granule assembly (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); nucleus (ortholog)Green Monkey7namegene, protein-coding, MODEL [RefSeq]
18915283Hecahdc homolog, cell cycle regulatorENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN negative regulation of mitotic cell cycle (ortholog); stress granule assembly (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); nucleus (ortholog)Naked Mole-Rat7namegene, protein-coding, MODEL [RefSeq]
20867338HECAhdc homolog, cell cycle regulatorENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN negative regulation of mitotic cell cycle (inferred); stress granule assembly (inferred); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); nucleus (inferred)Green Monkey6namegene, protein-coding
626090791Hecahdc homolog, cell cycle regulatorENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN negative regulation of mitotic cell cycle (ortholog); stress granule assembly (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); nucleus (ortholog)Black Rat7namegene, protein-coding, MODEL [RefSeq]
1602812DGAT2L6diacylglycerol O-acyltransferase 2 like 6This gene is a member of the diacylglycerol acyltransferase 2 family. The encoded protein is a putative acyltransferase and is most likely involved in the synthesis of di- or triacylglycerol, however its substrate specificity is currently unknown. [provided by RefSeq, Feb 2015]X7017748370205704Human28old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1323209MOGAT1monoacylglycerol O-acyltransferase 1Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and phospholipids (Yen et al., 2002 [PubMed 12077311]).[supplied by OMIM, Mar 2008]2222671658222709930Human116old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1316028MOGAT2monoacylglycerol O-acyltransferase 2The protein encoded by this gene is an enzyme that catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. The encoded protein is important in the uptake of dietary fat by the small intestine. This protein forms a complex with diacylglycerol O-acyltransferase 2 in the e117571783875732953Human99old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1350436MOGAT3monoacylglycerol O-acyltransferase 3Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008]7101192886101201036Human47old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1352867CLEC4AC-type lectin domain family 4 member AThis gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The enco1281029078138607Human115old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1345966SLC25A47solute carrier family 25 member 47This gene encodes a member of a large family of mitochondrial transporters. The nuclear-encoded carrier protein is embedded in the inner mitochondrial membrane. This member of the family is thought to be an uncoupling protein that uncouples mitochondrial respiration from ATP synthesis by dissipating14100323339100330421Human89old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1348381DCP1Bdecapping mRNA 1BThis gene encodes a member of a family of proteins that function in removing the 5' cap from mRNAs, which is a step in regulated mRNA decay. This protein localizes to cytoplasmic foci which are the site of mRNA breakdown and turnover. Alternative splicing results in multiple transcript variants. [pr1219415912004457Human83old_gene_name , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1320354Nudt4nudix hydrolase 4Enables snoRNA binding activity. Predicted to be involved in diphosphoinositol polyphosphate metabolic process and nucleotide catabolic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Orthologous to human NUDT4 (nudix hydrolase 4). [provided by Alliance 109538286995400008Mouse159old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1604373DSTYKdual serine/threonine and tyrosine protein kinaseThis gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]1205142505205211702Human151old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1314468ESF1ESF1 nucleolar pre-rRNA processing proteinEnables RNA binding activity. Predicted to be involved in rRNA processing. Located in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]201371432513784919Human79old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1320090KMT2Elysine methyltransferase 2E (inactive)This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized. [p7105014205105115019Human202old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1604813LARP7La ribonucleoprotein 7, transcriptional regulatorThis gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudoge4112637143112657586Human194old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1315499MRPS35mitochondrial ribosomal protein S35Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryot122771083227756295Human80old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1315944MS4A4Amembrane spanning 4-domains A4AThis gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features, similar intron/exon splice boundaries, and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. Alternatively spli116028066660308970Human51old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1320353NUDT4nudix hydrolase 4The protein encoded by this gene regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates ma129337792593408146Human162old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1322302PPIL4peptidylprolyl isomerase like 4This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. [provided by RefSeq, Jul 2008]6149504495149546043Human84old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1312554PSMG2proteasome assembly chaperone 2Enables molecular adaptor activity. Involved in chaperone-mediated protein complex assembly. Located in nucleus. Part of protein folding chaperone complex. Implicated in proteosome-associated autoinflammatory syndrome 4. [provided by Alliance of Genome Resources, Jul 2025]181265873812725740Human109old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1350050DCP1Adecapping mRNA 1ADecapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature te35328342953347543Human112old_gene_namegene, protein-coding, REVIEWED [RefSeq]