DCSTAMP (dendrocyte expressed seven transmembrane protein) - Rat Genome Database

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Gene: DCSTAMP (dendrocyte expressed seven transmembrane protein) Homo sapiens
Analyze
Symbol: DCSTAMP
Name: dendrocyte expressed seven transmembrane protein
RGD ID: 1321334
HGNC Page HGNC
Description: Involved in cellular response to interleukin-4. Localizes to cell surface and integral component of endoplasmic reticulum membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DC-specific transmembrane protein; dendritic cell-specific transmembrane protein; Dendritic cells (DC)-specific transmembrane protein; dendrocyte-expressed seven transmembrane protein; FIND; hDC-STAMP; IL-4-induced protein; IL-Four (IL-4) induced; IL-Four INDuced; IL-four-induced protein; MGC138223; MGC138225; MGC177336; TM7SF4; transmembrane 7 superfamily member 4
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8104,339,087 - 104,356,689 (+)EnsemblGRCh38hg38GRCh38
GRCh388104,339,087 - 104,356,874 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378105,352,024 - 105,368,917 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368105,421,230 - 105,438,092 (+)NCBINCBI36hg18NCBI36
Build 348105,421,229 - 105,438,092NCBI
Celera8101,538,720 - 101,555,582 (+)NCBI
Cytogenetic Map8q22.3NCBI
HuRef8100,553,073 - 100,569,966 (+)NCBIHuRef
CHM1_18105,392,829 - 105,409,722 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
1. GOA_HUMAN data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11169400   PMID:11345586   PMID:11345591   PMID:12477932   PMID:14702039   PMID:15489334   PMID:15601667   PMID:16344560   PMID:18952287   PMID:19259350   PMID:20546900   PMID:20586129  
PMID:20797317   PMID:20839008   PMID:21623375   PMID:21873635   PMID:21987375   PMID:22058328   PMID:23525827   PMID:24370779   PMID:25151085   PMID:25891874   PMID:26636523   PMID:28849122  
PMID:29145829   PMID:30705363  


Genomics

Comparative Map Data
DCSTAMP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl8104,339,087 - 104,356,689 (+)EnsemblGRCh38hg38GRCh38
GRCh388104,339,087 - 104,356,874 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378105,352,024 - 105,368,917 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368105,421,230 - 105,438,092 (+)NCBINCBI36hg18NCBI36
Build 348105,421,229 - 105,438,092NCBI
Celera8101,538,720 - 101,555,582 (+)NCBI
Cytogenetic Map8q22.3NCBI
HuRef8100,553,073 - 100,569,966 (+)NCBIHuRef
CHM1_18105,392,829 - 105,409,722 (+)NCBICHM1_1
Dcstamp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391539,609,326 - 39,624,334 (+)NCBIGRCm39mm39
GRCm39 Ensembl1539,609,326 - 39,624,334 (+)Ensembl
GRCm381539,745,930 - 39,760,938 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1539,745,930 - 39,760,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv371539,577,478 - 39,592,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv361539,576,006 - 39,591,008 (+)NCBImm8
Celera1540,229,920 - 40,244,989 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
Dcstamp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2770,807,455 - 70,822,067 (+)NCBI
Rnor_6.0 Ensembl778,649,875 - 78,650,906 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl778,732,904 - 78,741,588 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0778,725,173 - 78,756,160 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0777,597,411 - 77,598,623 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4775,318,788 - 75,336,382 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1775,349,840 - 75,357,112 (+)NCBI
Celera767,860,809 - 67,891,645 (+)NCBICelera
Cytogenetic Map7q31NCBI
Dcstamp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541728,155,842 - 28,168,049 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541728,156,046 - 28,169,481 (+)NCBIChiLan1.0ChiLan1.0
DCSTAMP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18103,121,332 - 103,138,223 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8103,121,332 - 103,138,223 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v08100,967,757 - 100,985,384 (+)NCBIMhudiblu_PPA_v0panPan3
DCSTAMP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1135,542,474 - 5,559,433 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl135,542,425 - 5,571,968 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha135,550,114 - 5,580,387 (+)NCBI
ROS_Cfam_1.0135,789,666 - 5,820,024 (+)NCBI
UMICH_Zoey_3.1135,558,282 - 5,588,532 (+)NCBI
UNSW_CanFamBas_1.0135,677,761 - 5,708,007 (+)NCBI
UU_Cfam_GSD_1.0135,699,620 - 5,729,895 (+)NCBI
LOC101960808
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530332,237,463 - 32,245,440 (-)NCBI
SpeTri2.0NW_00493647039,664,573 - 39,671,532 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCSTAMP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl432,913,152 - 32,928,235 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1432,912,320 - 32,928,323 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2435,670,769 - 35,685,853 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103237264
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1899,174,778 - 99,193,539 (+)NCBI
ChlSab1.1 Ensembl899,185,423 - 99,193,058 (+)Ensembl
Dcstamp
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476320,588,635 - 20,602,124 (+)NCBI

Position Markers
DCSTAMP__4680  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378105,368,379 - 105,369,061UniSTSGRCh37
Build 368105,437,555 - 105,438,237RGDNCBI36
Celera8101,555,045 - 101,555,727RGD
HuRef8100,569,428 - 100,570,110UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1360
Count of miRNA genes:742
Interacting mature miRNAs:834
Transcripts:ENST00000297581, ENST00000517364, ENST00000517991, ENST00000518023, ENST00000518051, ENST00000519562, ENST00000520080
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 19 1 5 1 25 6 1 75 21
Low 29 100 138 78 88 58 357 6 315 69 87 628 20 368 39
Below cutoff 1023 1328 1149 455 850 339 1534 827 2279 217 840 480 116 701 988 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001257317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_030788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011517321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011517324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024447288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024447289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024447290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF277290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF305068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK095417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP003471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC112018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC112020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC171732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA154308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HF548124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HG005332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HG005333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000297581   ⟹   ENSP00000297581
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8104,339,826 - 104,356,689 (+)Ensembl
RefSeq Acc Id: ENST00000517364
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8104,339,534 - 104,348,785 (+)Ensembl
RefSeq Acc Id: ENST00000517991   ⟹   ENSP00000428869
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8104,348,541 - 104,356,233 (+)Ensembl
RefSeq Acc Id: ENST00000518023
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8104,339,826 - 104,348,931 (+)Ensembl
RefSeq Acc Id: ENST00000518051
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8104,349,437 - 104,356,558 (+)Ensembl
RefSeq Acc Id: ENST00000519562
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8104,339,087 - 104,348,674 (+)Ensembl
RefSeq Acc Id: ENST00000520080
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8104,355,056 - 104,356,689 (+)Ensembl
RefSeq Acc Id: ENST00000622554   ⟹   ENSP00000480546
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl8104,339,796 - 104,356,688 (+)Ensembl
RefSeq Acc Id: NM_001257317   ⟹   NP_001244246
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388104,339,796 - 104,356,689 (+)NCBI
GRCh378105,352,024 - 105,368,917 (+)NCBI
HuRef8100,553,073 - 100,569,966 (+)NCBI
CHM1_18105,392,829 - 105,409,722 (+)NCBI
Sequence:
RefSeq Acc Id: NM_030788   ⟹   NP_110415
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388104,339,826 - 104,356,689 (+)NCBI
GRCh378105,352,024 - 105,368,917 (+)NCBI
Build 368105,421,230 - 105,438,092 (+)NCBI Archive
Celera8101,538,720 - 101,555,582 (+)RGD
HuRef8100,553,073 - 100,569,966 (+)NCBI
CHM1_18105,392,829 - 105,409,722 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011517321   ⟹   XP_011515623
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388104,339,087 - 104,356,689 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011517324   ⟹   XP_011515626
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388104,339,087 - 104,356,689 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024447288   ⟹   XP_024303056
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388104,339,826 - 104,356,689 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024447289   ⟹   XP_024303057
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388104,339,826 - 104,356,874 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024447290   ⟹   XP_024303058
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388104,339,826 - 104,356,501 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_110415   ⟸   NM_030788
- Peptide Label: isoform 1
- UniProtKB: Q9H295 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001244246   ⟸   NM_001257317
- Peptide Label: isoform 2
- UniProtKB: Q9H295 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011515623   ⟸   XM_011517321
- Peptide Label: isoform X1
- UniProtKB: Q9H295 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011515626   ⟸   XM_011517324
- Peptide Label: isoform X3
- UniProtKB: Q9H295 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_024303057   ⟸   XM_024447289
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_024303056   ⟸   XM_024447288
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024303058   ⟸   XM_024447290
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSP00000428869   ⟸   ENST00000517991
RefSeq Acc Id: ENSP00000480546   ⟸   ENST00000622554
RefSeq Acc Id: ENSP00000297581   ⟸   ENST00000297581

Promoters
RGD ID:7213959
Promoter ID:EPDNEW_H12724
Type:multiple initiation site
Name:DCSTAMP_1
Description:dendrocyte expressed seven transmembrane protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388104,339,826 - 104,339,886EPDNEW
RGD ID:6850570
Promoter ID:EP73076
Type:initiation region
Name:HS_LOC81501
Description:DC-specific transmembrane protein.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 368105,421,230 - 105,421,290EPD

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:95606052-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|See cases [RCV000053677] Chr8:95606052..145054775 [GRCh38]
Chr8:96618280..146280161 [GRCh37]
Chr8:96687456..146250965 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000053602] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:244417-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|See cases [RCV000053604] Chr8:244417..145054775 [GRCh38]
Chr8:194417..146280161 [GRCh37]
Chr8:184417..146250965 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:94682154-145068656)x3 copy number gain See cases [RCV000134353] Chr8:94682154..145068656 [GRCh38]
Chr8:95694382..146294042 [GRCh37]
Chr8:95763558..146264846 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q22.3-23.1(chr8:101884819-107356143)x1 copy number loss See cases [RCV000134099] Chr8:101884819..107356143 [GRCh38]
Chr8:102897047..108368371 [GRCh37]
Chr8:102966223..108437547 [NCBI36]
Chr8:8q22.3-23.1
pathogenic
GRCh38/hg38 8q21.3-24.23(chr8:86300584-137022587)x3 copy number gain See cases [RCV000135621] Chr8:86300584..137022587 [GRCh38]
Chr8:87312813..138034830 [GRCh37]
Chr8:87381929..138104012 [NCBI36]
Chr8:8q21.3-24.23
pathogenic|likely pathogenic
GRCh38/hg38 8q22.3-23.1(chr8:101199826-105802098)x1 copy number loss See cases [RCV000136812] Chr8:101199826..105802098 [GRCh38]
Chr8:102212054..106814326 [GRCh37]
Chr8:102281230..106883502 [NCBI36]
Chr8:8q22.3-23.1
pathogenic
GRCh38/hg38 8q22.3-23.1(chr8:101171263-109127664)x1 copy number loss See cases [RCV000138134] Chr8:101171263..109127664 [GRCh38]
Chr8:102183491..110139893 [GRCh37]
Chr8:102252667..110209069 [NCBI36]
Chr8:8q22.3-23.1
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241605-145054781)x3 copy number gain See cases [RCV000138643] Chr8:241605..145054781 [GRCh38]
Chr8:191605..146280167 [GRCh37]
Chr8:181605..146250971 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.3-24.3(chr8:87931152-145068712)x3 copy number gain See cases [RCV000138551] Chr8:87931152..145068712 [GRCh38]
Chr8:88943380..146294098 [GRCh37]
Chr8:89012496..146264902 [NCBI36]
Chr8:8q21.3-24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:77480050-145068712)x3 copy number gain See cases [RCV000139036] Chr8:77480050..145068712 [GRCh38]
Chr8:78392286..146294098 [GRCh37]
Chr8:78554841..146264902 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:97382873-145070385)x3 copy number gain See cases [RCV000140447] Chr8:97382873..145070385 [GRCh38]
Chr8:98395101..146295771 [GRCh37]
Chr8:98464277..146266575 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q11.1-24.3(chr8:46031340-139285494)x3 copy number gain See cases [RCV000139539] Chr8:46031340..139285494 [GRCh38]
Chr8:46942962..140297737 [GRCh37]
Chr8:47062127..140366919 [NCBI36]
Chr8:8q11.1-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:208048-145070385)x3 copy number gain See cases [RCV000141808] Chr8:208048..145070385 [GRCh38]
Chr8:158048..146295771 [GRCh37]
Chr8:148048..146266575 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:100867343-145070385)x3 copy number gain See cases [RCV000141694] Chr8:100867343..145070385 [GRCh38]
Chr8:101879571..146295771 [GRCh37]
Chr8:101948747..146266575 [NCBI36]
Chr8:8q22.3-24.3
pathogenic
GRCh38/hg38 8q22.2-23.1(chr8:100179408-106524667)x1 copy number loss See cases [RCV000141697] Chr8:100179408..106524667 [GRCh38]
Chr8:101191636..107536895 [GRCh37]
Chr8:101260812..107606071 [NCBI36]
Chr8:8q22.2-23.1
pathogenic
GRCh38/hg38 8p21.3-q24.3(chr8:21291522-145070385)x3 copy number gain See cases [RCV000142021] Chr8:21291522..145070385 [GRCh38]
Chr8:21149033..146295771 [GRCh37]
Chr8:21193313..146266575 [NCBI36]
Chr8:8p21.3-q24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:103306336-145068712)x3 copy number gain See cases [RCV000142810] Chr8:103306336..145068712 [GRCh38]
Chr8:104318564..146294098 [GRCh37]
Chr8:104387740..146264902 [NCBI36]
Chr8:8q22.3-24.3
pathogenic|likely pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:226452-145068712)x3 copy number gain See cases [RCV000142858] Chr8:226452..145068712 [GRCh38]
Chr8:176452..146294098 [GRCh37]
Chr8:166452..146264902 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:78614077-145054634)x3 copy number gain See cases [RCV000142597] Chr8:78614077..145054634 [GRCh38]
Chr8:79526312..146280020 [GRCh37]
Chr8:79688867..146250824 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000148092] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.2-24.3(chr8:85765999-145070385)x3 copy number gain See cases [RCV000143659] Chr8:85765999..145070385 [GRCh38]
Chr8:86778228..146295771 [GRCh37]
Chr8:86863079..146266575 [NCBI36]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158991-146280828)x3 copy number gain See cases [RCV000447507] Chr8:158991..146280828 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q22.1-24.3(chr8:98432250-146222672)x4 copy number gain See cases [RCV000448954] Chr8:98432250..146222672 [GRCh37]
Chr8:8q22.1-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771) copy number gain See cases [RCV000510234] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.3-24.3(chr8:93047482-141355635)x3 copy number gain See cases [RCV000511761] Chr8:93047482..141355635 [GRCh37]
Chr8:8q21.3-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771)x3 copy number gain See cases [RCV000511095] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841154-146295771)x3 copy number gain See cases [RCV000511002] Chr8:86841154..146295771 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841228-142689874)x3 copy number gain See cases [RCV000510854] Chr8:86841228..142689874 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8p23.1-q24.3(chr8:12490999-146295771)x3 copy number gain See cases [RCV000512169] Chr8:12490999..146295771 [GRCh37]
Chr8:8p23.1-q24.3
pathogenic
GRCh37/hg19 8q21.2-23.3(chr8:86841154-116518125)x3 copy number gain not provided [RCV000683045] Chr8:86841154..116518125 [GRCh37]
Chr8:8q21.2-23.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:164984-146293414)x3 copy number gain not provided [RCV000747254] Chr8:164984..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:10213-146293414)x3 copy number gain not provided [RCV000747248] Chr8:10213..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q22.3-23.3(chr8:104437051-114170843)x1 copy number loss not provided [RCV000847013] Chr8:104437051..114170843 [GRCh37]
Chr8:8q22.3-23.3
uncertain significance
GRCh37/hg19 8p12-q24.3(chr8:31936551-146295771)x3 copy number gain not provided [RCV000848192] Chr8:31936551..146295771 [GRCh37]
Chr8:8p12-q24.3
pathogenic
GRCh37/hg19 8q22.3(chr8:104878013-105555692)x3 copy number gain not provided [RCV000849601] Chr8:104878013..105555692 [GRCh37]
Chr8:8q22.3
uncertain significance
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771)x3 copy number gain not provided [RCV000848478] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:18549 AgrOrtholog
COSMIC DCSTAMP COSMIC
Ensembl Genes ENSG00000164935 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000297581 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000428869 UniProtKB/Swiss-Prot
  ENSP00000480546 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000297581 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000517991 UniProtKB/Swiss-Prot
  ENST00000622554 ENTREZGENE, UniProtKB/Swiss-Prot
GTEx ENSG00000164935 GTEx
HGNC ID HGNC:18549 ENTREZGENE
Human Proteome Map DCSTAMP Human Proteome Map
InterPro DC_STAMP-like UniProtKB/Swiss-Prot
KEGG Report hsa:81501 UniProtKB/Swiss-Prot
NCBI Gene 81501 ENTREZGENE
OMIM 605933 OMIM
Pfam DC_STAMP UniProtKB/Swiss-Prot
PharmGKB PA134938623 PharmGKB
UniProt DCSTP_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B7ZVW2 UniProtKB/Swiss-Prot
  E7ESG0 UniProtKB/Swiss-Prot
  Q2M2D5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-04-03 DCSTAMP  dendrocyte expressed seven transmembrane protein  TM7SF4  transmembrane 7 superfamily member 4  Symbol and/or name change 5135510 APPROVED