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35 records found for search term Erbb3
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
69323Erbb3erb-b2 receptor tyrosine kinase 3ENCODES a protein that exhibits neuregulin binding; neuregulin receptor activity; ErbB-3 class receptor binding (ortholog); INVOLVED IN axonogenesis; cellular response to insulin stimulus; cellular response to mechanical stimulus; PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway;715790791600379Rat389symbol , old_gene_name , PhenoGen , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
733426ERBB3erb-b2 receptor tyrosine kinase 3This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosph125608010856103505Human505symbol , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
736142Erbb3erb-b2 receptor tyrosine kinase 3Enables neuregulin receptor activity. Involved in ERBB2-ERBB3 signaling pathway; Schwann cell development; and myelination. Acts upstream of or within several processes, including negative regulation of motor neuron apoptotic process; nervous system development;10128403392128425504Mouse524symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
8743330Erbb3erb-b2 receptor tyrosine kinase 3ENCODES a protein that exhibits ErbB-3 class receptor binding (ortholog); growth factor binding (ortholog); identical protein binding (ortholog); INVOLVED IN axonogenesis (ortholog); cell surface receptor protein tyrosine kinase signaling pathway (ortholog); cellular response to insulin stimulus (orNW_00495545836831263701752Chinchilla155symbolgene, protein-coding, MODEL [RefSeq]
11724570ERBB3erb-b2 receptor tyrosine kinase 3ENCODES a protein that exhibits neuregulin binding (ortholog); neuregulin receptor activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN axonogenesis (ortholog); cellular response to insulin stimulus (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATE123281153332834958Bonobo178symbolgene, protein-coding, MODEL [RefSeq]
12260744ERBB3erb-b2 receptor tyrosine kinase 3ENCODES a protein that exhibits neuregulin binding (ortholog); neuregulin receptor activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN axonogenesis (ortholog); cellular response to insulin stimulus (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATE10406856424746Dog177symbolgene, protein-coding, MODEL [RefSeq]
12447578Erbb3erb-b2 receptor tyrosine kinase 3ENCODES a protein that exhibits neuregulin binding (ortholog); neuregulin receptor activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN axonogenesis (ortholog); cellular response to insulin stimulus (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATENW_004936646497783515247Squirrel172symbolgene, protein-coding, MODEL [RefSeq]
14112474ERBB3erb-b2 receptor tyrosine kinase 3ENCODES a protein that exhibits neuregulin binding (ortholog); neuregulin receptor activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN axonogenesis (ortholog); cellular response to insulin stimulus (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATEPig177symbolgene, protein-coding, MODEL [RefSeq]
15039251ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); nucleotide binding (inferred); INVOLVED IN cell surface receptor protein tyrosine kinase signaling pathway (inferred); FOUND IN membrane (inferred)Pig15symbolgene, protein-coding
18405147ERBB3erb-b2 receptor tyrosine kinase 3ENCODES a protein that exhibits neuregulin binding (ortholog); neuregulin receptor activity (ortholog); protein tyrosine kinase activity (ortholog); INVOLVED IN axonogenesis (ortholog); cellular response to insulin stimulus (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATEGreen Monkey172symbolgene, protein-coding, MODEL [RefSeq]
18903428Erbb3erb-b2 receptor tyrosine kinase 3ENCODES a protein that exhibits ErbB-3 class receptor binding (ortholog); growth factor binding (ortholog); identical protein binding (ortholog); INVOLVED IN axonogenesis (ortholog); cellular response to insulin stimulus (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATES INaked Mole-Rat170symbolgene, protein-coding, MODEL [RefSeq]
155245114erbb3Tropical Clawed Frogsymbolgene, null
625853027Erbb3erb-b2 receptor tyrosine kinase 3ENCODES a protein that exhibits ErbB-3 class receptor binding (ortholog); growth factor binding (ortholog); identical protein binding (ortholog); INVOLVED IN axonogenesis (ortholog); cell surface receptor protein tyrosine kinase signaling pathway (ortholog); cellular response to insulin stimulus (orBlack Rat153symbolgene, protein-coding, MODEL [RefSeq]
155245115erbb3.LAfrican Clawed Frogsymbolgene, null
155236574erbb3.SAfrican Clawed Frogsymbolgene, null
1302994Pa2g4proliferation-associated 2G4ENCODES a protein that exhibits nucleic acid binding (ortholog); transcription corepressor activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN negative regulation of apoptotic process; positive regulation of cell differentiation; negative regulation of DNA-templated transcr715693261576794Rat174old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1332087Pa2g4proliferation-associated 2G4Predicted to enable nucleic acid binding activity; transcription corepressor activity; and ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of apoptotic process and positive regulation of cell differentiation. Predicted to act upstream of or within negative 10128393635128401803Mouse198old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1354307PA2G4proliferation-associated 2G4This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytop125610455956113910Human181old_gene_name , descriptiongene, protein-coding, REVIEWED [RefSeq]
8948702Map2k2mitogen-activated protein kinase kinase 2ENCODES a protein that exhibits ATP binding (ortholog); MAP kinase kinase activity (ortholog); MAP-kinase scaffold activity (ortholog); INVOLVED IN epithelial cell proliferation involved in lung morphogenesis (ortholog); ERBB2-ERBB3 signaling pathway (ortholog);NW_00495549546952394718380Chinchilla111descriptiongene, protein-coding, MODEL [RefSeq]
11981791MAP2K2mitogen-activated protein kinase kinase 2ENCODES a protein that exhibits ATP binding (ortholog); MAP kinase kinase activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN epithelial cell proliferation involved in lung morphogenesis (ortholog); ERBB2-ERBB3 signaling pathway (ortholog); E1931144453148619Bonobo124descriptiongene, protein-coding, MODEL [RefSeq]
12428789MAP2K2mitogen-activated protein kinase kinase 2ENCODES a protein that exhibits ATP binding (ortholog); MAP kinase kinase activity (ortholog); MAP-kinase scaffold activity (ortholog); INVOLVED IN epithelial cell proliferation involved in lung morphogenesis (ortholog); ERBB2-ERBB3 signaling pathway (ortholog);205546546055487629Dog134descriptiongene, protein-coding, VALIDATED [RefSeq]
14072870MAP2K2mitogen-activated protein kinase kinase 2ENCODES a protein that exhibits ATP binding (ortholog); MAP kinase kinase activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN epithelial cell proliferation involved in lung morphogenesis (ortholog); ERBB2-ERBB3 signaling pathway (ortholog); EPig116descriptiongene, protein-coding, VALIDATED [RefSeq]
18900513Map2k2mitogen-activated protein kinase kinase 2ENCODES a protein that exhibits ATP binding (ortholog); MAP kinase kinase activity (ortholog); MAP-kinase scaffold activity (ortholog); INVOLVED IN epithelial cell proliferation involved in lung morphogenesis (ortholog); ERBB2-ERBB3 signaling pathway (ortholog);Naked Mole-Rat128descriptiongene, protein-coding, MODEL [RefSeq]
625936760Map2k2mitogen-activated protein kinase kinase 2ENCODES a protein that exhibits ATP binding (ortholog); MAP kinase kinase activity (ortholog); MAP-kinase scaffold activity (ortholog); INVOLVED IN epithelial cell proliferation involved in lung morphogenesis (ortholog); ERBB2-ERBB3 signaling pathway (ortholog);Black Rat107descriptiongene, protein-coding, MODEL [RefSeq]
734341MyocmyocilinEnables receptor tyrosine kinase binding activity. Involved in several processes, including ERBB2-ERBB3 signaling pathway; neurogenesis; and skeletal muscle hypertrophy. Located in several cellular components, including Golgi apparatus; endoplasmic reticulum; an1162466719162477263Mouse208descriptiongene, protein-coding, VALIDATED [RefSeq]
1612360Nrg2neuregulin 2Enables receptor ligand activity. Involved in ERBB2-ERBB3 signaling pathway and ERBB4-ERBB4 signaling pathway. Is active in extracellular space. Is expressed in epidermis; heart; mammary gland primordium; nervous system; and surface ectoderm. Orthologous to huma183614763436332754Mouse131descriptiongene, protein-coding, VALIDATED [RefSeq]
8813137Nrg2neuregulin 2ENCODES a protein that exhibits epidermal growth factor receptor activity (ortholog); epidermal growth factor receptor binding (ortholog); ErbB-3 class receptor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); epidermal growth factor receptor signaling pathway (ortNW_004955418548624793861Chinchilla29descriptiongene, protein-coding, MODEL [RefSeq]
11891171NRG2neuregulin 2ENCODES a protein that exhibits epidermal growth factor receptor activity (ortholog); epidermal growth factor receptor binding (ortholog); ErbB-3 class receptor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); epidermal growth factor receptor signaling pathway (ort5135212496135411469Bonobo39descriptiongene, protein-coding, MODEL [RefSeq]
12362760NRG2neuregulin 2ENCODES a protein that exhibits epidermal growth factor receptor activity (ortholog); epidermal growth factor receptor binding (ortholog); ErbB-3 class receptor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); epidermal growth factor receptor signaling pathway (ort23508519235264509Dog36descriptiongene, protein-coding, MODEL [RefSeq]
12670916Nrg2neuregulin 2ENCODES a protein that exhibits epidermal growth factor receptor activity (ortholog); epidermal growth factor receptor binding (ortholog); ErbB-3 class receptor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); epidermal growth factor receptor signaling pathway (ortNW_00493653188845659064541Squirrel36descriptiongene, protein-coding, MODEL [RefSeq]
14250438NRG2neuregulin 2ENCODES a protein that exhibits epidermal growth factor receptor activity (ortholog); epidermal growth factor receptor binding (ortholog); ErbB-3 class receptor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); epidermal growth factor receptor signaling pathway (ortPig36descriptiongene, protein-coding, MODEL [RefSeq]
18516648NRG2neuregulin 2ENCODES a protein that exhibits epidermal growth factor receptor activity (ortholog); epidermal growth factor receptor binding (ortholog); ErbB-3 class receptor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); epidermal growth factor receptor signaling pathway (ortGreen Monkey39descriptiongene, protein-coding, MODEL [RefSeq]
18918917Nrg2neuregulin 2ENCODES a protein that exhibits epidermal growth factor receptor activity (ortholog); epidermal growth factor receptor binding (ortholog); ErbB-3 class receptor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); epidermal growth factor receptor signaling pathway (ortNaked Mole-Rat36descriptiongene, protein-coding, MODEL [RefSeq]
626115651Nrg2neuregulin 2ENCODES a protein that exhibits epidermal growth factor receptor activity (ortholog); epidermal growth factor receptor binding (ortholog); ErbB-3 class receptor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); epidermal growth factor receptor signaling pathway (ortBlack Rat29descriptiongene, protein-coding, MODEL [RefSeq]
1317640NRG3neuregulin 3This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling casca108187519482987179Human98descriptiongene, protein-coding, REVIEWED [RefSeq]