NRG2 (neuregulin 2) - Rat Genome Database

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Gene: NRG2 (neuregulin 2) Canis lupus familiaris
Analyze
Symbol: NRG2
Name: neuregulin 2
RGD ID: 12362760
Description: ENCODES a protein that exhibits epidermal growth factor receptor activity (ortholog); epidermal growth factor receptor binding (ortholog); ErbB-3 class receptor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); epidermal growth factor receptor signaling pathway (ortholog); ERBB2-ERBB3 signaling pathway (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal dominant intellectual developmental disorder 31 (ortholog); familial adenomatous polyposis 1 (ortholog); FOUND IN extracellular space (ortholog); GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC111091859; pro-neuregulin-2, membrane-bound isoform; uncharacterized LOC111091859
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,085,192 - 35,264,509 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,085,361 - 35,264,378 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,188,379 - 32,434,387 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0235,540,482 - 35,786,931 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl235,540,758 - 35,596,619 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1232,592,831 - 32,839,160 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0233,459,495 - 33,706,597 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,211,046 - 34,457,510 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NRG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,085,192 - 35,264,509 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,085,361 - 35,264,378 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,188,379 - 32,434,387 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0235,540,482 - 35,786,931 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl235,540,758 - 35,596,619 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1232,592,831 - 32,839,160 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0233,459,495 - 33,706,597 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,211,046 - 34,457,510 (-)NCBIUU_Cfam_GSD_1.0
NRG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385139,846,781 - 140,043,299 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5139,846,779 - 140,043,299 (-)EnsemblGRCh38hg38GRCh38
GRCh375139,226,366 - 139,422,884 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365139,207,444 - 139,403,063 (-)NCBINCBI36Build 36hg18NCBI36
Celera5135,301,792 - 135,498,704 (-)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5134,369,651 - 134,566,061 (-)NCBIHuRef
CHM1_15138,659,474 - 138,855,994 (-)NCBICHM1_1
T2T-CHM13v2.05140,371,883 - 140,568,402 (-)NCBIT2T-CHM13v2.0
Nrg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,147,634 - 36,332,754 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1836,150,705 - 36,330,433 (-)EnsemblGRCm39 Ensembl
GRCm381836,014,581 - 36,197,532 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,017,652 - 36,197,380 (-)EnsemblGRCm38mm10GRCm38
MGSCv371836,177,303 - 36,356,814 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361836,177,303 - 36,356,814 (-)NCBIMGSCv36mm8
Celera1836,474,450 - 36,653,084 (-)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.38NCBI
Nrg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81827,890,578 - 28,072,538 (-)NCBIGRCr8
mRatBN7.21827,616,542 - 27,798,505 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1827,619,661 - 27,798,505 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1827,743,902 - 27,925,871 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,505,789 - 28,687,737 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01827,840,647 - 28,022,647 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01828,835,391 - 29,015,552 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,835,417 - 29,015,552 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,544,864 - 28,724,922 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41828,650,097 - 28,828,772 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11828,676,749 - 28,855,418 (-)NCBI
Celera1827,350,962 - 27,529,758 (-)NCBICelera
Cytogenetic Map18p11NCBI
Nrg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955418548,624 - 793,861 (+)NCBIChiLan1.0ChiLan1.0
NRG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24135,109,036 - 135,304,138 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15133,248,589 - 133,444,133 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05135,212,496 - 135,411,469 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15141,333,911 - 141,528,420 (-)NCBIpanpan1.1PanPan1.1panPan2
Nrg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213152,546,964 - 152,728,032 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365318,884,642 - 9,064,869 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365318,884,565 - 9,064,541 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NRG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2141,662,369 - 141,824,727 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12141,660,936 - 141,825,281 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22147,549,110 - 147,575,155 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NRG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12342,498,367 - 42,694,330 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2342,499,503 - 42,692,968 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603435,126,483 - 35,386,932 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nrg2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474332,620,295 - 32,810,391 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474332,620,025 - 32,810,990 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NRG2
1302 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 4 1 8
Low 4 15 2 6 11 10 6
Below cutoff 1 5 6 6 6 6

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022408389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022408390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022408391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038658605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038658606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038658607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038658608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038658609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038658610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000009237   ⟹   ENSCAFP00000008572
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl235,085,361 - 35,264,378 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000067401   ⟹   ENSCAFP00000058378
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl235,085,361 - 35,264,378 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000086500   ⟹   ENSCAFP00000055200
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl235,085,361 - 35,264,378 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845001841   ⟹   ENSCAFP00845001451
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl235,540,758 - 35,596,619 (-)Ensembl
RefSeq Acc Id: XM_022408389   ⟹   XP_022264097
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1235,085,192 - 35,264,509 (-)NCBI
Dog10K_Boxer_Tasha232,188,379 - 32,367,397 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022408390   ⟹   XP_022264098
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1235,085,192 - 35,264,508 (-)NCBI
Dog10K_Boxer_Tasha232,188,656 - 32,434,386 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038457890   ⟹   XP_038313818
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha232,188,656 - 32,434,387 (-)NCBI
RefSeq Acc Id: XM_038457893   ⟹   XP_038313821
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha232,188,656 - 32,429,327 (-)NCBI
RefSeq Acc Id: XM_038457900   ⟹   XP_038313828
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha232,188,656 - 32,434,387 (-)NCBI
RefSeq Acc Id: XM_038457906   ⟹   XP_038313834
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha232,188,656 - 32,434,387 (-)NCBI
RefSeq Acc Id: XM_038469548   ⟹   XP_038325476
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1232,593,108 - 32,839,160 (-)NCBI
RefSeq Acc Id: XM_038469549   ⟹   XP_038325477
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1232,593,108 - 32,834,099 (-)NCBI
RefSeq Acc Id: XM_038469550   ⟹   XP_038325478
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1232,592,831 - 32,771,929 (-)NCBI
RefSeq Acc Id: XM_038469551   ⟹   XP_038325479
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1232,593,108 - 32,839,159 (-)NCBI
RefSeq Acc Id: XM_038469552   ⟹   XP_038325480
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1232,593,108 - 32,839,160 (-)NCBI
RefSeq Acc Id: XM_038469553   ⟹   XP_038325481
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1232,593,108 - 32,839,160 (-)NCBI
RefSeq Acc Id: XM_038530311   ⟹   XP_038386239
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0234,211,323 - 34,457,510 (-)NCBI
RefSeq Acc Id: XM_038530312   ⟹   XP_038386240
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0234,211,323 - 34,452,448 (-)NCBI
RefSeq Acc Id: XM_038530313   ⟹   XP_038386241
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0234,211,046 - 34,390,124 (-)NCBI
RefSeq Acc Id: XM_038530314   ⟹   XP_038386242
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0234,211,323 - 34,457,509 (-)NCBI
RefSeq Acc Id: XM_038530315   ⟹   XP_038386243
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0234,211,323 - 34,457,510 (-)NCBI
RefSeq Acc Id: XM_038530316   ⟹   XP_038386244
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0234,211,323 - 34,457,510 (-)NCBI
RefSeq Acc Id: XM_038594558   ⟹   XP_038450486
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0233,459,772 - 33,706,597 (-)NCBI
RefSeq Acc Id: XM_038594559   ⟹   XP_038450487
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0233,459,772 - 33,701,533 (-)NCBI
RefSeq Acc Id: XM_038594560   ⟹   XP_038450488
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0233,459,495 - 33,638,541 (-)NCBI
RefSeq Acc Id: XM_038594561   ⟹   XP_038450489
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0233,459,772 - 33,706,596 (-)NCBI
RefSeq Acc Id: XM_038594563   ⟹   XP_038450491
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0233,459,772 - 33,706,597 (-)NCBI
RefSeq Acc Id: XM_038594564   ⟹   XP_038450492
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0233,459,772 - 33,706,597 (-)NCBI
RefSeq Acc Id: XM_038658605   ⟹   XP_038514533
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0235,540,759 - 35,786,931 (-)NCBI
RefSeq Acc Id: XM_038658606   ⟹   XP_038514534
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0235,540,759 - 35,781,871 (-)NCBI
RefSeq Acc Id: XM_038658607   ⟹   XP_038514535
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0235,540,482 - 35,719,668 (-)NCBI
RefSeq Acc Id: XM_038658608   ⟹   XP_038514536
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0235,540,759 - 35,786,930 (-)NCBI
RefSeq Acc Id: XM_038658609   ⟹   XP_038514537
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0235,540,759 - 35,786,931 (-)NCBI
RefSeq Acc Id: XM_038658610   ⟹   XP_038514538
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0235,540,759 - 35,786,931 (-)NCBI
Protein Sequences
Protein RefSeqs XP_022264097 (Get FASTA)   NCBI Sequence Viewer  
  XP_022264098 (Get FASTA)   NCBI Sequence Viewer  
  XP_038313818 (Get FASTA)   NCBI Sequence Viewer  
  XP_038313821 (Get FASTA)   NCBI Sequence Viewer  
  XP_038313828 (Get FASTA)   NCBI Sequence Viewer  
  XP_038313834 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325476 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325477 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325478 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325479 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325480 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325481 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386239 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386240 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386241 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386242 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386243 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386244 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450486 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450487 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450488 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450489 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450491 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450492 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514533 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514534 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514535 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514536 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514537 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514538 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000008572.5
  ENSCAFP00000055200.1
  ENSCAFP00000058378.1
  ENSCAFP00000067795.1
  ENSCAFP00000068425.1
  ENSCAFP00000069777.1
  ENSCAFP00000070204.1
  ENSCAFP00030006324.1
  ENSCAFP00030006393.1
  ENSCAFP00030006444.1
  ENSCAFP00030006515.1
  ENSCAFP00030006578.1
  ENSCAFP00030006628.1
  ENSCAFP00040005280.1
  ENSCAFP00845001451.1
RefSeq Acc Id: XP_022264097   ⟸   XM_022408389
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAK4 (UniProtKB/TrEMBL),   A0A8P0PJ64 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022264098   ⟸   XM_022408390
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M8H3 (UniProtKB/TrEMBL),   A0A8P0N8D4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000008572   ⟸   ENSCAFT00000009237
RefSeq Acc Id: ENSCAFP00000055200   ⟸   ENSCAFT00000086500
RefSeq Acc Id: ENSCAFP00000058378   ⟸   ENSCAFT00000067401
RefSeq Acc Id: XP_038325478   ⟸   XM_038469550
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038325481   ⟸   XM_038469553
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038325480   ⟸   XM_038469552
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038325476   ⟸   XM_038469548
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038325479   ⟸   XM_038469551
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038325477   ⟸   XM_038469549
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038450488   ⟸   XM_038594560
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038450492   ⟸   XM_038594564
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038450491   ⟸   XM_038594563
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038450486   ⟸   XM_038594558
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038450489   ⟸   XM_038594561
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038450487   ⟸   XM_038594559
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038514535   ⟸   XM_038658607
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAK4 (UniProtKB/TrEMBL),   A0A8P0PJ64 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514538   ⟸   XM_038658610
- Peptide Label: isoform X4
- UniProtKB: A0A8C0MB71 (UniProtKB/TrEMBL),   A0A8P0P4K7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514537   ⟸   XM_038658609
- Peptide Label: isoform X3
- UniProtKB: A0A8C0MC92 (UniProtKB/TrEMBL),   A0A8P0TMW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514533   ⟸   XM_038658605
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAK4 (UniProtKB/TrEMBL),   A0A8P0PJ64 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514536   ⟸   XM_038658608
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M8H3 (UniProtKB/TrEMBL),   A0A8P0N8D4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514534   ⟸   XM_038658606
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAK4 (UniProtKB/TrEMBL),   A0A8P0PJ64 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038313834   ⟸   XM_038457906
- Peptide Label: isoform X4
- UniProtKB: A0A8C0MB71 (UniProtKB/TrEMBL),   A0A8P0P4K7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038313828   ⟸   XM_038457900
- Peptide Label: isoform X3
- UniProtKB: A0A8C0MC92 (UniProtKB/TrEMBL),   A0A8P0TMW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038313818   ⟸   XM_038457890
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAK4 (UniProtKB/TrEMBL),   A0A8P0PJ64 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038313821   ⟸   XM_038457893
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAK4 (UniProtKB/TrEMBL),   A0A8P0PJ64 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386241   ⟸   XM_038530313
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAK4 (UniProtKB/TrEMBL),   A0A8P0PJ64 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386244   ⟸   XM_038530316
- Peptide Label: isoform X4
- UniProtKB: A0A8C0MB71 (UniProtKB/TrEMBL),   A0A8P0P4K7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386243   ⟸   XM_038530315
- Peptide Label: isoform X3
- UniProtKB: A0A8C0MC92 (UniProtKB/TrEMBL),   A0A8P0TMW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386239   ⟸   XM_038530311
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAK4 (UniProtKB/TrEMBL),   A0A8P0PJ64 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386242   ⟸   XM_038530314
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M8H3 (UniProtKB/TrEMBL),   A0A8P0N8D4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386240   ⟸   XM_038530312
- Peptide Label: isoform X1
- UniProtKB: A0A8C0MAK4 (UniProtKB/TrEMBL),   A0A8P0PJ64 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845001451   ⟸   ENSCAFT00845001841
Protein Domains
EGF-like   Ig-like

Promoters
RGD ID:13682439
Promoter ID:EPDNEW_C507
Type:initiation region
Name:NRG2_1
Description:neuregulin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1235,264,242 - 35,264,302EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005731 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030003826 UniProtKB/TrEMBL
  ENSCAFG00040003222 UniProtKB/TrEMBL
  ENSCAFG00845001070 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000009237.6 UniProtKB/TrEMBL
  ENSCAFT00000067401.2 UniProtKB/TrEMBL
  ENSCAFT00000086500.2 UniProtKB/TrEMBL
  ENSCAFT00000098721.1 UniProtKB/TrEMBL
  ENSCAFT00000102383.1 UniProtKB/TrEMBL
  ENSCAFT00000106186.1 UniProtKB/TrEMBL
  ENSCAFT00000107391.1 UniProtKB/TrEMBL
  ENSCAFT00030007218.1 UniProtKB/TrEMBL
  ENSCAFT00030007293.1 UniProtKB/TrEMBL
  ENSCAFT00030007351.1 UniProtKB/TrEMBL
  ENSCAFT00030007426.1 UniProtKB/TrEMBL
  ENSCAFT00030007505.1 UniProtKB/TrEMBL
  ENSCAFT00030007564.1 UniProtKB/TrEMBL
  ENSCAFT00040006115.1 UniProtKB/TrEMBL
  ENSCAFT00845001841.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Neuregulin UniProtKB/TrEMBL
  Neuregulin_C UniProtKB/TrEMBL
NCBI Gene NRG2 ENTREZGENE
PANTHER PRO-NEUREGULIN-2, MEMBRANE-BOUND ISOFORM UniProtKB/TrEMBL
  PTHR11100 UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
  Neuregulin UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A0A8C0M8H3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0M964_CANLF UniProtKB/TrEMBL
  A0A8C0MAK4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MB71 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MC92 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MFX7_CANLF UniProtKB/TrEMBL
  A0A8C0PWQ0_CANLF UniProtKB/TrEMBL
  A0A8I3MN72_CANLF UniProtKB/TrEMBL
  A0A8P0N8D4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0P4K7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PJ64 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TAC7_CANLF UniProtKB/TrEMBL
  A0A8P0TJE9_CANLF UniProtKB/TrEMBL
  A0A8P0TMW1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43968 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-14 NRG2  neuregulin 2  LOC111091859  uncharacterized LOC111091859  Data merged from RGD:13314842 737654 PROVISIONAL