ERBB3 (erb-b2 receptor tyrosine kinase 3) - Rat Genome Database
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Gene: ERBB3 (erb-b2 receptor tyrosine kinase 3) Pan paniscus
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Symbol: ERBB3
Name: erb-b2 receptor tyrosine kinase 3
RGD ID: 11724570
Description: ENCODES a protein that exhibits ErbB-3 class receptor binding (ortholog); growth factor binding (ortholog); identical protein binding (ortholog); INVOLVED IN axonogenesis (ortholog); cellular response to insulin stimulus (ortholog); circadian rhythm (ortholog); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH Acute Erythroleukemia (ortholog); bladder urothelial carcinoma (ortholog); breast cancer (ortholog); FOUND IN apical part of cell (ortholog); apical plasma membrane (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: receptor tyrosine-protein kinase erbB-3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11233,062,681 - 33,085,426 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,063,434 - 33,084,994 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01232,811,533 - 32,834,958 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
ERBB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11233,062,681 - 33,085,426 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,063,434 - 33,084,994 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01232,811,533 - 32,834,958 (-)NCBIMhudiblu_PPA_v0panPan3
ERBB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1256,076,799 - 56,103,505 (+)EnsemblGRCh38hg38GRCh38
GRCh381256,080,108 - 56,103,505 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371256,473,892 - 56,497,289 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,760,159 - 54,783,395 (+)NCBINCBI36hg18NCBI36
Build 341254,760,158 - 54,783,395NCBI
Celera1256,125,560 - 56,149,315 (+)NCBI
Cytogenetic Map12q13.2NCBI
HuRef1253,512,788 - 53,536,430 (+)NCBIHuRef
CHM1_11256,441,254 - 56,464,656 (+)NCBICHM1_1
Erbb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,403,392 - 128,425,504 (-)NCBIGRCm39mm39
GRCm39 Ensembl10128,403,392 - 128,425,521 (-)Ensembl
GRCm3810128,567,523 - 128,589,635 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,567,523 - 128,589,652 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710128,006,424 - 128,026,557 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610127,972,317 - 127,992,450 (-)NCBImm8
Celera10130,961,356 - 130,981,519 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.1NCBI
Erbb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27994,549 - 1,015,876 (-)NCBI
Rnor_6.0 Ensembl72,989,340 - 3,010,350 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.072,989,202 - 3,010,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.072,962,964 - 2,984,938 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,858,057 - 1,877,353 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.171,858,056 - 1,877,353 (-)NCBI
Celera7866,587 - 885,873 (-)NCBICelera
Cytogenetic Map7q11NCBI
Erbb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,683,126 - 3,702,978 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,683,126 - 3,701,752 (+)NCBIChiLan1.0ChiLan1.0
ERBB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl10406,633 - 424,264 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.110406,856 - 424,746 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Erbb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936646497,783 - 515,247 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERBB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,431,656 - 21,496,279 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,474,218 - 21,495,040 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,085,940 - 23,092,633 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ERBB3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,020,912 - 52,043,809 (+)NCBI
ChlSab1.1 Ensembl1152,021,058 - 52,044,028 (+)Ensembl
Erbb3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480211,906,279 - 11,925,530 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000047421   ⟹   ENSPPAP00000024596
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1233,063,434 - 33,084,994 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000047429   ⟹   ENSPPAP00000024604
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1233,063,434 - 33,084,994 (-)Ensembl
RefSeq Acc Id: XM_034935667   ⟹   XP_034791558
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01232,811,533 - 32,834,958 (-)NCBI
RefSeq Acc Id: XM_034935669   ⟹   XP_034791560
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01232,811,533 - 32,831,698 (-)NCBI
RefSeq Acc Id: XM_034935670   ⟹   XP_034791561
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01232,811,533 - 32,829,369 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034791558 (Get FASTA)   NCBI Sequence Viewer  
  XP_034791560 (Get FASTA)   NCBI Sequence Viewer  
  XP_034791561 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_034791558   ⟸   XM_034935667
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034791560   ⟸   XM_034935669
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034791561   ⟸   XM_034935670
- Peptide Label: isoform X3
RefSeq Acc Id: ENSPPAP00000024604   ⟸   ENSPPAT00000047429
RefSeq Acc Id: ENSPPAP00000024596   ⟸   ENSPPAT00000047421
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035409 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000024596 UniProtKB/TrEMBL
  ENSPPAP00000024604 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047421 UniProtKB/TrEMBL
  ENSPPAT00000047429 UniProtKB/TrEMBL
Gene3D-CATH 3.80.20.20 UniProtKB/TrEMBL
InterPro Furin-like_Cys-rich_dom UniProtKB/TrEMBL
  Furin_repeat UniProtKB/TrEMBL
  GF_recep_IV UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Rcpt_L-dom UniProtKB/TrEMBL
  Rcpt_L-dom_sf UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_EGF/ERB/XmrK_rcpt UniProtKB/TrEMBL
NCBI Gene ERBB3 ENTREZGENE
Pfam Furin-like UniProtKB/TrEMBL
  GF_recep_IV UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/TrEMBL
  Recep_L_domain UniProtKB/TrEMBL
PIRSF TyrPK_EGF-R UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
SMART SM00261 UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A2R9B6A5_PANPA UniProtKB/TrEMBL
  A0A2R9BBP6_PANPA UniProtKB/TrEMBL