Map2k2 (mitogen-activated protein kinase kinase 2)

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Gene: Map2k2 (mitogen-activated protein kinase kinase 2) Chinchilla lanigera

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Symbol:

Map2k2

Name:

mitogen-activated protein kinase kinase 2

RGD ID:

8948702

Description:

ENCODES a protein that exhibits ATP binding (ortholog); MAP kinase kinase activity (ortholog); MAP-kinase scaffold activity (ortholog); INVOLVED IN epithelial cell proliferation involved in lung morphogenesis (ortholog); ERBB2-ERBB3 signaling pathway (ortholog); ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN adenosine signaling pathway; ceramide signaling pathway; endothelin signaling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); amenorrhea (ortholog); breast cancer (ortholog); FOUND IN cell cortex (ortholog); cell-cell junction (ortholog); cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

dual specificity mitogen-activated protein kinase kinase 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	4,695,768 - 4,722,098 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	4,695,239 - 4,718,380 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adenoid cystic carcinoma (ISO)

amenorrhea (ISO)

breast cancer (ISO)

cardiofaciocutaneous syndrome (ISO)

cardiofaciocutaneous syndrome 1 (ISO)

cardiofaciocutaneous syndrome 4 (ISO)

colorectal cancer (ISO)

Costello syndrome (ISO)

Dwarfism (ISO)

gastric adenocarcinoma (ISO)

glioblastoma (ISO)

head and neck squamous cell carcinoma (ISO)

hepatocellular carcinoma (ISO)

hypertrophic cardiomyopathy (ISO)

Hypotension (ISO)

lung non-small cell carcinoma (ISO)

melanoma (ISO)

Metabolic Syndrome (ISO)

migraine (ISO)

mitral valve prolapse (ISO)

multicentric Castleman disease (ISO)

neurofibromatosis-Noonan syndrome (ISO)

Noonan syndrome (ISO)

Noonan syndrome 1 (ISO)

Noonan syndrome with multiple lentigines (ISO)

Ovarian Neoplasms (ISO)

Pain (ISO)

pancreatic adenocarcinoma (ISO)

Prostatic Neoplasms (ISO)

RASopathy (ISO)

skin melanoma (ISO)

small intestine adenocarcinoma (ISO)

Smith-Magenis syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

epithelial cell proliferation involved in lung morphogenesis (ISO)

ERBB2-ERBB3 signaling pathway (ISO)

ERK1 and ERK2 cascade (ISO)

face development (ISO)

heart development (ISO)

insulin-like growth factor receptor signaling pathway (ISO)

lung morphogenesis (ISO)

MAPK cascade (ISO)

myelination (ISO)

negative regulation of gene expression (ISO)

peptidyl-serine autophosphorylation (ISO)

peptidyl-tyrosine phosphorylation (ISO)

positive regulation of axonogenesis (ISO)

positive regulation of cell motility (ISO)

positive regulation of DNA-templated transcription (ISO)

positive regulation of gene expression (ISO)

positive regulation of protein serine/threonine kinase activity (ISO)

protein phosphorylation (ISO)

regulation of axon regeneration (ISO)

response to ischemia (ISO)

Schwann cell development (ISO)

thymus development (ISO)

thyroid gland development (ISO)

trachea formation (ISO)

Cellular Component

cell cortex (ISO)

cell-cell junction (ISO)

cytoplasm (ISO)

cytoplasmic side of plasma membrane (ISO)

endoplasmic reticulum (ISO)

Golgi apparatus (ISO)

microtubule (ISO)

perinuclear region of cytoplasm (ISO)

Molecular Function

ATP binding (ISO)

MAP kinase kinase activity (ISO)

MAP-kinase scaffold activity (ISO)

molecular adaptor activity (ISO)

PDZ domain binding (ISO)

protein binding (ISO)

protein serine/threonine kinase activator activity (ISO)

scaffold protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

adenosine signaling pathway (ISO)

ceramide signaling pathway (ISO)

endothelin signaling pathway (ISO)

Fc epsilon receptor mediated signaling pathway (ISO)

granulocyte-macrophage colony-stimulating factor signaling pathway (ISO)

insulin signaling pathway (ISO)

interleukin-2 signaling pathway (ISO)

mTOR signaling pathway (ISO)

platelet-derived growth factor signaling pathway (ISO)

the extracellular signal-regulated Raf/Mek/Erk signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Map2k2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	4,695,768 - 4,722,098 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	4,695,239 - 4,718,380 (+)	NCBI	ChiLan1.0	ChiLan1.0

MAP2K2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	4,090,321 - 4,124,122 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	4,090,321 - 4,124,122 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	4,090,319 - 4,124,119 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	4,041,319 - 4,075,126 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	4,041,321 - 4,075,126	NCBI
Celera	19	4,029,762 - 4,063,598 (-)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	3,854,052 - 3,888,086 (-)	NCBI		HuRef
CHM1_1	19	4,089,923 - 4,123,692 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	4,073,480 - 4,107,423 (-)	NCBI		T2T-CHM13v2.0

Map2k2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	80,941,749 - 80,960,531 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	80,941,749 - 80,969,809 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	81,105,913 - 81,124,697 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	81,105,915 - 81,133,975 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	80,568,692 - 80,587,442 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	80,509,092 - 80,527,465 (+)	NCBI		MGSCv36	mm8
Celera	10	82,126,303 - 82,145,053 (+)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Map2k2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	9,241,449 - 9,264,216 (-)	NCBI		GRCr8
mRatBN7.2	7	8,590,729 - 8,610,279 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	8,580,905 - 8,610,243 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	11,475,464 - 11,494,812 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	13,350,953 - 13,370,301 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	11,217,425 - 11,236,805 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	11,458,971 - 11,478,520 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	11,458,967 - 11,478,489 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	11,626,294 - 11,645,884 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	10,074,654 - 10,094,003 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	10,074,657 - 10,094,003 (-)	NCBI
Celera	7	6,778,257 - 6,797,606 (-)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

MAP2K2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	8,488,392 - 8,523,027 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	7,718,541 - 7,752,382 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	3,114,445 - 3,148,619 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	4,064,626 - 4,097,933 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	4,064,626 - 4,097,933 (-)	Ensembl	panpan1.1		panPan2

MAP2K2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	55,465,460 - 55,487,629 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	55,465,212 - 55,487,641 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	55,191,875 - 55,213,954 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	56,128,646 - 56,148,204 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	20	55,182,690 - 55,204,761 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	55,664,143 - 55,686,194 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	55,862,931 - 55,885,022 (+)	NCBI		UU_Cfam_GSD_1.0

Map2k2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	215,457,693 - 215,496,652 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	2,336,858 - 2,377,090 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	2,338,127 - 2,377,090 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAP2K2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	74,626,783 - 74,651,348 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	74,626,739 - 74,651,352 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	75,170,854 - 75,195,463 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAP2K2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	3,848,441 - 3,881,367 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	3,848,401 - 3,881,412 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666081	4,347,082 - 4,394,579 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Map2k2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	5,488,814 - 5,511,445 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	5,489,085 - 5,511,166 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005405811	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01061943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01061944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01001978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01008504	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000017239 ⟹ ENSCLAP00000017071

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955495	4,695,768 - 4,722,098 (+)	Ensembl

RefSeq Acc Id:

XM_005405811 ⟹ XP_005405868

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955495	4,695,239 - 4,718,380 (+)	NCBI

Sequence:

show sequence

CCTTTGTCTCTGGGGAGGCGGGGTCGAACGCCTGCGCACCCCCCGCGCCGGAGGGGTGGGGTCC
GTCGCAGCTCGCGGCGCTCGTTTGCTCTCGCGAGAGTCCGGCGCGCGATCTCGTGGCCGCCCCC
TCCTCTCCTTCGGCCTCCAGGCTCTGGCTGCAGCGTCAGCGGCCCCTTTACCTCAGCGCCGGCG
TCCTCGGCGCCCCTCCCCCGGCCTGGTCCGCCGGCCGCCCGCCCCTGGCTTCCCCGGCGCCGCC
CTAGGCCGCGGCCGCAGCCCCGGGCTCTTGTCGGCTCCGCCCGCTCGCGGCCCGCCCCCTATGG
GCCCCGGCTAGAGGCGCCGCCGCCACCGGCCCGCGGAGCCCCGATGCTGGCCCGGAGGAAGCCG
GTGCTGCCGGCGCTCACCATCAACCCCGCCGCCGCCGAGGGCCCGTCCCCCACCAGCGAGGGCG
CCTCCGAAGCGAACCTGGTGGACCTGCAAAAGAAGCTAGAGGAACTGGAACTAGATGAGCAGCA
GAAGAAGCGGCTTGAGGCCTTCCTCACCCAGAAAGCCAAGGTCGGCGAGCTTAAGGACGACGAC
TTTGAACGGATCTCAGAGCTGGGGGCCGGCAATGGCGGTGTGGTCACCAAGGTCCAGCACAGAC
CATCAGGCCTCATCATGGCCCGGAAGCTCATCCACCTGGAGATCAAGCCGGCCATCCGCAACCA
GATCATCCGCGAGCTGCAAGTGCTGCACGAGTGCAACTCGCCCTACATTGTGGGCTTCTATGGG
GCCTTCTATAGCGACGGGGAGATCAGCATCTGCATGGAGCATATGGACGGCGGCTCCCTTGACC
AGGTGCTGAAGGAAGCCAAGCGGATTCCCGAGGAAATCCTGGGGAAAGTCAGCATTGCGGTGCT
CCGGGGCCTGGCGTACCTCCGGGAGAAGCACCAGATCATGCACCGAGATGTGAAACCATCCAAC
ATCCTGGTCAACTCCCGAGGGGAGATCAAGCTGTGCGACTTCGGGGTGAGCGGGCAGCTCATCG
ACTCCATGGCCAACTCCTTCGTGGGAACTCGATCCTACATGTCTCCAGAGCGGCTGCAGGGCAC
GCACTACTCAGTACAGTCGGACATCTGGAGCATGGGACTGTCCCTGGTGGAGCTGTCCATCGGC
AGGTACCCCATCCCCCCACCCGACGCCAAGGAGCTGGAGGCCATCTTCGGCCGGCCAGTGCTCG
ACGGCACAGAAGGACAGCCCCAGAGCATCTCACCGCGGCCCCGGCCGCCTGGACGCCCCATCAG
CGGTCATGGAATGGACAGCCGGCCTGCCATGGCCATCTTTGAGCTGCTAGACTACATCGTGAAT
GAGCCGCCGCCCAAGCTGCCCAGTGGTGTGTTCAGCCTGGATTTCCAGGAGTTTGTAAATAAAT
GCCTCATTAAGAACCCAGCGGAGCGCGCAGATCTGAAGATGCTCATGAACCACGCCTTCATCAA
GCGCTCCGAAGTGGAGGAGGTGGACTTCGCCGGCTGGCTGTGCAGGACCCTGCGCCTCAACCAG
CCCAGCACGCCGACGCGAACCGCTGTCTGACAGCGCCCGCCTGGTCCCGCCAGCCACCTCTCCT
GCCCGTCTGGGCTGCGCTCTGGCCCTGCCAGGACAGGCCCGCGCTTCTCACCCTCCGCCCCAGG
GGCCTTGGTGTCCGCGTCCCCAGGGGAGGGTGACGCGTGCCTGCTGTCATCGGGACCCTGCTTC
CTTAGGCCTATACACAAGGAAACAAAACGAGAAGAAACTGCACACGCTG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005405868	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000017071
	ENSCLAP00000017071.1

RefSeq Acc Id:

XP_005405868 ⟸ XM_005405811

- UniProtKB:

A0A8C2VT07 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLARRKPVLPALTINPAAAEGPSPTSEGASEANLVDLQKKLEELELDEQQKKRLEAFLTQKAKV
GELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSP
YIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMH
RDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLS
LVELSIGRYPIPPPDAKELEAIFGRPVLDGTEGQPQSISPRPRPPGRPISGHGMDSRPAMAIFE
LLDYIVNEPPPKLPSGVFSLDFQEFVNKCLIKNPAERADLKMLMNHAFIKRSEVEEVDFAGWLC
RTLRLNQPSTPTRTAV

hide sequence

Ensembl Acc Id:

ENSCLAP00000017071 ⟸ ENSCLAT00000017239

Protein Domains

Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000011717	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000017239	ENTREZGENE
	ENSCLAT00000017239.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	MAP_kinase_kinase	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
NCBI Gene	Map2k2	ENTREZGENE
PANTHER	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN	UniProtKB/TrEMBL
	PROTEIN KINASE DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	A0A8C2VT07	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)