Symbol:
Gpam
Name:
glycerol-3-phosphate acyltransferase, mitochondrial
RGD ID:
61847
Description:
Enables glycerol-3-phosphate O-acyltransferase activity. Involved in several processes, including cellular response to insulin stimulus; glycerolipid biosynthetic process; and positive regulation of triglyceride biosynthetic process. Located in mitochondrial outer membrane. Biomarker of metabolic dysfunction-associated steatotic liver disease; nephrotic syndrome; and obesity. Orthologous to human GPAM (glycerol-3-phosphate acyltransferase, mitochondrial); PARTICIPATES IN D-glycericacidemia pathway; familial lipoprotein lipase deficiency pathway; glycerol kinase deficiency pathway; INTERACTS WITH (+)-catechin; (+)-schisandrin B; (-)-epigallocatechin 3-gallate.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
glycerol-3-phosphate acyltransferase 1, mitochondrial; GPAT; GPAT-1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
GPAM (glycerol-3-phosphate acyltransferase, mitochondrial) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Gpam (glycerol-3-phosphate acyltransferase, mitochondrial) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Gpam (glycerol-3-phosphate acyltransferase, mitochondrial) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
GPAM (glycerol-3-phosphate acyltransferase, mitochondrial) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
GPAM (glycerol-3-phosphate acyltransferase, mitochondrial) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Gpam (glycerol-3-phosphate acyltransferase, mitochondrial) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
GPAM (glycerol-3-phosphate acyltransferase, mitochondrial) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
GPAM (glycerol-3-phosphate acyltransferase, mitochondrial) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Gpam (glycerol-3-phosphate acyltransferase, mitochondrial) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
FOXI1 (forkhead box I1) HGNC
OMA
Alliance orthologs 3
Mus musculus (house mouse):
Gpam (glycerol-3-phosphate acyltransferase, mitochondrial)
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
GPAM (glycerol-3-phosphate acyltransferase, mitochondrial)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
gpam (glycerol-3-phosphate acyltransferase, mitochondrial)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
acl-6
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
mino
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 264,111,599 - 264,176,112 (-) NCBI GRCr8 mRatBN7.2 1 254,106,323 - 254,170,755 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 254,106,331 - 254,142,639 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 262,315,818 - 262,376,481 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 269,021,904 - 269,082,569 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 261,664,129 - 261,730,618 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 275,843,823 - 275,906,880 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 275,846,819 - 275,906,686 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 283,246,186 - 283,309,245 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 261,370,264 - 261,431,434 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 261,581,308 - 261,642,479 (-) NCBI Celera 1 249,818,009 - 249,877,839 (-) NCBI Celera Cytogenetic Map 1 q55 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Gpam Rat (+)-catechin multiple interactions EXP 6480464 Catechin inhibits the reaction [Dietary Fats results in increased expression of GPAM mRNA] CTD PMID:23365609 Gpam Rat (+)-catechin multiple interactions ISO Gpam (Mus musculus) 6480464 [Catechin co-treated with Dietary Fats] affects the expression of GPAM mRNA CTD PMID:25861419 Gpam Rat (+)-dexrazoxane decreases expression ISO Gpam (Mus musculus) 6480464 Dexrazoxane results in decreased expression of GPAM mRNA CTD PMID:26873546 Gpam Rat (+)-dexrazoxane multiple interactions ISO Gpam (Mus musculus) 6480464 [Doxorubicin co-treated with Dexrazoxane] results in increased expression of GPAM mRNA CTD PMID:26873546 Gpam Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of GPAM mRNA] CTD PMID:31150632 Gpam Rat (-)-epigallocatechin 3-gallate decreases expression EXP 6480464 epigallocatechin gallate results in decreased expression of GPAM mRNA CTD PMID:16988119 Gpam Rat (1->4)-beta-D-glucan multiple interactions ISO Gpam (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GPAM mRNA CTD PMID:36331819 Gpam Rat 1,2-dimethylhydrazine decreases expression ISO Gpam (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of GPAM mRNA CTD PMID:22206623 Gpam Rat 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of GPAM mRNA CTD PMID:25380136 Gpam Rat 17alpha-ethynylestradiol multiple interactions ISO Gpam (Mus musculus) 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Ethinyl Estradiol] results in increased expression of GPAM mRNA and [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GPAM mRNA CTD PMID:17942748 and PMID:24440342 Gpam Rat 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of GPAM mRNA CTD PMID:15576828 Gpam Rat 17beta-estradiol decreases expression ISO GPAM (Homo sapiens) 6480464 Estradiol results in decreased expression of GPAM mRNA CTD PMID:20106945 Gpam Rat 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of GPAM protein CTD PMID:32145629 Gpam Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Gpam (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GPAM mRNA more ... CTD PMID:16054899 more ... Gpam Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO GPAM (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of GPAM mRNA CTD PMID:30096437 Gpam Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Gpam (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of GPAM mRNA CTD PMID:28213091 Gpam Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of GPAM mRNA CTD PMID:20959002 and PMID:33387578 Gpam Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of GPAM mRNA CTD PMID:22808131 Gpam Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Gpam (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of GPAM mRNA CTD PMID:21570461 Gpam Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO GPAM (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of GPAM mRNA CTD PMID:22298810 Gpam Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Gpam (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of GPAM mRNA CTD PMID:18295293 Gpam Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of GPAM mRNA CTD PMID:21346803 Gpam Rat 2-methylcholine affects expression ISO GPAM (Homo sapiens) 6480464 beta-methylcholine affects the expression of GPAM mRNA CTD PMID:21179406 Gpam Rat 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:20959002 and PMID:23196670 Gpam Rat 3,4-methylenedioxymethamphetamine increases expression ISO Gpam (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of GPAM mRNA CTD PMID:20188158 Gpam Rat 3,4-methylenedioxymethamphetamine increases methylation ISO Gpam (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of GPAM promoter CTD PMID:26251327 Gpam Rat 3,4-methylenedioxymethamphetamine decreases expression ISO Gpam (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of GPAM mRNA CTD PMID:26251327 Gpam Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Gpam (Mus musculus) 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNA more ... CTD PMID:16054899 Gpam Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO GPAM (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of GPAM mRNA CTD PMID:28628672 Gpam Rat 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of GPAM mRNA CTD PMID:25380136 and PMID:30723492 Gpam Rat 4,4'-sulfonyldiphenol decreases expression ISO Gpam (Mus musculus) 6480464 bisphenol S results in decreased expression of GPAM mRNA CTD PMID:33297965 Gpam Rat 4,4'-sulfonyldiphenol affects methylation ISO Gpam (Mus musculus) 6480464 bisphenol S affects the methylation of GPAM gene CTD PMID:31683443 Gpam Rat 4-hydroxyphenyl retinamide decreases expression ISO Gpam (Mus musculus) 6480464 Fenretinide results in decreased expression of GPAM mRNA CTD PMID:28973697 Gpam Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of GPAM mRNA CTD PMID:24780913 Gpam Rat acadesine multiple interactions ISO GPAM (Homo sapiens) 6480464 acadesine inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein] and acadesine inhibits the reaction [Dibutyl Phthalate results in increased expression of GPAM protein] CTD PMID:33508418 Gpam Rat aflatoxin B1 decreases methylation ISO GPAM (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of GPAM gene CTD PMID:27153756 Gpam Rat aflatoxin B1 decreases expression ISO GPAM (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of GPAM mRNA CTD PMID:22100608 and PMID:27153756 Gpam Rat aldrin increases expression ISO Gpam (Mus musculus) 6480464 Aldrin results in increased expression of GPAM mRNA CTD PMID:18579281 Gpam Rat all-trans-retinoic acid decreases expression ISO GPAM (Homo sapiens) 6480464 Tretinoin results in decreased expression of GPAM mRNA CTD PMID:33167477 Gpam Rat amiodarone increases expression EXP 6480464 Amiodarone results in increased expression of GPAM mRNA CTD PMID:19224547 Gpam Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of GPAM mRNA CTD PMID:16483693 Gpam Rat Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of GPAM mRNA CTD PMID:18178546 Gpam Rat atorvastatin calcium multiple interactions EXP 6480464 Atorvastatin inhibits the reaction [Fructose results in increased expression of GPAM mRNA] CTD PMID:19053045 Gpam Rat atrazine multiple interactions ISO Gpam (Mus musculus) 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Atrazine] results in increased expression of GPAM mRNA CTD PMID:24440342 Gpam Rat atrazine decreases expression ISO GPAM (Homo sapiens) 6480464 Atrazine results in decreased expression of GPAM mRNA CTD PMID:22378314 Gpam Rat benzo[a]pyrene decreases expression ISO Gpam (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of GPAM mRNA CTD PMID:19770486 and PMID:22228805 Gpam Rat benzo[a]pyrene increases methylation ISO GPAM (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of GPAM promoter CTD PMID:27901495 Gpam Rat benzo[a]pyrene decreases expression ISO GPAM (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of GPAM mRNA CTD PMID:26238291 and PMID:32234424 Gpam Rat benzo[a]pyrene affects expression ISO Gpam (Mus musculus) 6480464 Benzo(a)pyrene affects the expression of GPAM mRNA CTD PMID:22342234 Gpam Rat benzo[a]pyrene diol epoxide I decreases expression ISO GPAM (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 Gpam Rat benzo[a]pyrene diol epoxide I affects expression ISO GPAM (Homo sapiens) 6480464 7 more ... CTD PMID:26238291 Gpam Rat benzylpenicillin increases expression ISO Gpam (Mus musculus) 6480464 Penicillin G results in increased expression of GPAM mRNA CTD PMID:27503388 Gpam Rat benzylpenicillin multiple interactions ISO Gpam (Mus musculus) 6480464 [Penicillin G co-treated with Erythromycin] results in increased expression of GPAM mRNA CTD PMID:27503388 Gpam Rat beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GPAM mRNA CTD PMID:18164116 Gpam Rat bezafibrate multiple interactions ISO Gpam (Mus musculus) 6480464 PPARA protein affects the susceptibility to [Bezafibrate results in increased expression of GPAM mRNA] CTD PMID:19124612 Gpam Rat bezafibrate increases expression ISO Gpam (Mus musculus) 6480464 Bezafibrate results in increased expression of GPAM mRNA and Bezafibrate results in increased expression of GPAM protein CTD PMID:19124612 Gpam Rat bezafibrate decreases expression ISO Gpam (Mus musculus) 6480464 Bezafibrate results in decreased expression of GPAM mRNA and Bezafibrate results in decreased expression of GPAM protein CTD PMID:19124612 Gpam Rat bisphenol A increases expression ISO GPAM (Homo sapiens) 6480464 bisphenol A results in increased expression of GPAM mRNA CTD PMID:25619500 and PMID:28483554 Gpam Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GPAM mRNA and bisphenol A results in increased expression of GPAM protein CTD PMID:30816183 more ... Gpam Rat bisphenol A affects expression ISO GPAM (Homo sapiens) 6480464 bisphenol A affects the expression of GPAM mRNA CTD PMID:30903817 Gpam Rat bisphenol A multiple interactions ISO GPAM (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of GPAM gene and MIR192 mRNA inhibits the reaction [bisphenol A results in increased expression of GPAM mRNA] CTD PMID:28483554 and PMID:31601247 Gpam Rat bisphenol A increases expression ISO Gpam (Mus musculus) 6480464 bisphenol A results in increased expression of GPAM mRNA CTD PMID:21932408 more ... Gpam Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of GPAM mRNA CTD PMID:25181051 Gpam Rat bisphenol AF increases expression ISO GPAM (Homo sapiens) 6480464 bisphenol AF results in increased expression of GPAM protein CTD PMID:34186270 Gpam Rat Bisphenol B increases expression ISO GPAM (Homo sapiens) 6480464 bisphenol B results in increased expression of GPAM protein CTD PMID:34186270 Gpam Rat bisphenol F increases expression ISO Gpam (Mus musculus) 6480464 bisphenol F results in increased expression of GPAM mRNA CTD PMID:38685157 Gpam Rat bisphenol F increases expression ISO GPAM (Homo sapiens) 6480464 bisphenol F results in increased expression of GPAM protein CTD PMID:34186270 Gpam Rat bromuconazole increases expression EXP 6480464 bromuconazole results in increased expression of GPAM mRNA CTD PMID:33789219 Gpam Rat buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of GPAM mRNA CTD PMID:24136188 Gpam Rat cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of GPAM mRNA CTD PMID:17066326 Gpam Rat cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of GPAM mRNA CTD PMID:17066326 and PMID:18329778 Gpam Rat cadmium dichloride increases expression ISO Gpam (Mus musculus) 6480464 Cadmium Chloride results in increased expression of GPAM mRNA CTD PMID:26352046 Gpam Rat caffeine increases phosphorylation ISO GPAM (Homo sapiens) 6480464 Caffeine results in increased phosphorylation of GPAM protein CTD PMID:35688186 Gpam Rat carbon nanotube decreases expression ISO Gpam (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25620056 Gpam Rat chloroethene increases expression ISO Gpam (Mus musculus) 6480464 Vinyl Chloride results in increased expression of GPAM mRNA CTD PMID:18579281 Gpam Rat chlorothalonil multiple interactions ISO Gpam (Mus musculus) 6480464 [procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of GPAM mRNA CTD PMID:33246813 Gpam Rat chlorothalonil decreases expression ISO Gpam (Mus musculus) 6480464 tetrachloroisophthalonitrile results in decreased expression of GPAM mRNA CTD PMID:33246813 Gpam Rat chlorpyrifos decreases expression ISO Gpam (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of GPAM mRNA CTD PMID:37019170 Gpam Rat cholesterol multiple interactions ISO Gpam (Mus musculus) 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Atrazine] results in increased expression of GPAM mRNA and [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Ethinyl Estradiol] results in increased expression of GPAM mRNA CTD PMID:24440342 Gpam Rat choline multiple interactions ISO Gpam (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GPAM gene CTD PMID:20938992 Gpam Rat clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of GPAM mRNA CTD PMID:19224547 Gpam Rat copper(II) sulfate affects expression ISO GPAM (Homo sapiens) 6480464 Copper Sulfate affects the expression of GPAM mRNA CTD PMID:19549813 Gpam Rat coumarin increases phosphorylation ISO GPAM (Homo sapiens) 6480464 coumarin results in increased phosphorylation of GPAM protein CTD PMID:35688186 Gpam Rat crocidolite asbestos decreases expression ISO GPAM (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased expression of GPAM mRNA CTD PMID:24160326 Gpam Rat curcumin decreases expression ISO Gpam (Mus musculus) 6480464 Curcumin results in decreased expression of GPAM mRNA CTD PMID:19297423 Gpam Rat curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of GPAM mRNA CTD PMID:27208389 Gpam Rat curcumin affects expression ISO Gpam (Mus musculus) 6480464 Curcumin affects the expression of GPAM mRNA CTD PMID:27208389 Gpam Rat curcumin multiple interactions ISO Gpam (Mus musculus) 6480464 Curcumin inhibits the reaction [Dietary Fats results in increased expression of GPAM mRNA] CTD PMID:19297423 Gpam Rat cyclosporin A decreases expression ISO GPAM (Homo sapiens) 6480464 Cyclosporine results in decreased expression of GPAM mRNA CTD PMID:20106945 more ... Gpam Rat cyclosporin A affects expression ISO GPAM (Homo sapiens) 6480464 Cyclosporine affects the expression of GPAM mRNA CTD PMID:25562108 Gpam Rat decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of GPAM mRNA CTD PMID:23640034 Gpam Rat dexamethasone multiple interactions ISO Gpam (Mus musculus) 6480464 [Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of GPAM mRNA more ... CTD PMID:16054899 Gpam Rat dexamethasone multiple interactions ISO GPAM (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of GPAM mRNA CTD PMID:28628672 Gpam Rat dexamethasone increases expression ISO GPAM (Homo sapiens) 6480464 Dexamethasone results in increased expression of GPAM mRNA CTD PMID:25047013 Gpam Rat dibutyl phthalate multiple interactions EXP 6480464 Dibutyl Phthalate promotes the reaction [Dietary Fats results in increased expression of GPAM protein] CTD PMID:33508418 Gpam Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of GPAM protein CTD PMID:33508418 Gpam Rat dibutyl phthalate increases expression ISO GPAM (Homo sapiens) 6480464 Dibutyl Phthalate results in increased expression of GPAM protein CTD PMID:33508418 Gpam Rat dibutyl phthalate multiple interactions ISO GPAM (Homo sapiens) 6480464 [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein more ... CTD PMID:33508418 Gpam Rat dichloroacetic acid increases expression ISO Gpam (Mus musculus) 6480464 Dichloroacetic Acid results in increased expression of GPAM mRNA CTD PMID:28962523 Gpam Rat diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of GPAM mRNA CTD PMID:37077353 Gpam Rat dioxygen multiple interactions ISO Gpam (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of GPAM mRNA CTD PMID:30529165 Gpam Rat doxorubicin decreases expression ISO Gpam (Mus musculus) 6480464 Doxorubicin results in decreased expression of GPAM mRNA CTD PMID:26873546 Gpam Rat doxorubicin multiple interactions ISO Gpam (Mus musculus) 6480464 [Doxorubicin co-treated with Dexrazoxane] results in increased expression of GPAM mRNA CTD PMID:26873546 Gpam Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of GPAM mRNA CTD PMID:29391264 Gpam Rat entacapone decreases expression ISO GPAM (Homo sapiens) 6480464 entacapone results in decreased expression of GPAM protein CTD PMID:29688484 Gpam Rat epoxiconazole decreases expression ISO Gpam (Mus musculus) 6480464 epoxiconazole results in decreased expression of GPAM mRNA CTD PMID:35436446 Gpam Rat erythromycin A increases expression ISO Gpam (Mus musculus) 6480464 Erythromycin results in increased expression of GPAM mRNA CTD PMID:27503388 Gpam Rat erythromycin A multiple interactions ISO Gpam (Mus musculus) 6480464 [Penicillin G co-treated with Erythromycin] results in increased expression of GPAM mRNA CTD PMID:27503388 Gpam Rat ethanol multiple interactions ISO Gpam (Mus musculus) 6480464 [Zinc deficiency co-treated with Ethanol] results in decreased expression of GPAM mRNA more ... CTD PMID:18755807 more ... Gpam Rat ethanol decreases expression ISO GPAM (Homo sapiens) 6480464 Ethanol results in decreased expression of GPAM mRNA CTD PMID:23378141 Gpam Rat ethanol increases expression ISO Gpam (Mus musculus) 6480464 Ethanol results in increased expression of GPAM mRNA CTD PMID:18755807 more ... Gpam Rat fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of GPAM mRNA CTD PMID:16707586 Gpam Rat fentin chloride decreases expression EXP 6480464 triphenyltin chloride results in decreased expression of GPAM mRNA CTD PMID:37156404 Gpam Rat flutamide decreases expression ISO Gpam (Mus musculus) 6480464 Flutamide results in decreased expression of GPAM mRNA CTD PMID:17702527 and PMID:19442681 Gpam Rat folic acid multiple interactions ISO Gpam (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GPAM gene CTD PMID:20938992 Gpam Rat folic acid multiple interactions EXP 6480464 [Folic Acid affects the susceptibility to Fructose] which affects the expression of GPAM mRNA CTD PMID:31612177 Gpam Rat FR900359 increases phosphorylation ISO GPAM (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of GPAM protein CTD PMID:37730182 Gpam Rat fructose multiple interactions EXP 6480464 [Folic Acid affects the susceptibility to Fructose] which affects the expression of GPAM mRNA and Atorvastatin inhibits the reaction [Fructose results in increased expression of GPAM mRNA] CTD PMID:19053045 and PMID:31612177 Gpam Rat fructose increases expression EXP 6480464 Fructose results in increased expression of GPAM mRNA CTD PMID:18346472 and PMID:19053045 Gpam Rat fulvestrant multiple interactions ISO GPAM (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of GPAM gene CTD PMID:31601247 Gpam Rat fumonisin B1 decreases expression ISO Gpam (Mus musculus) 6480464 fumonisin B1 results in decreased expression of GPAM mRNA CTD PMID:16221962 Gpam Rat genistein increases expression ISO Gpam (Mus musculus) 6480464 Genistein results in increased expression of GPAM mRNA CTD PMID:32186404 Gpam Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of GPAM mRNA CTD PMID:22061828 and PMID:33387578 Gpam Rat ginsenoside Re multiple interactions ISO Gpam (Mus musculus) 6480464 ginsenoside Re inhibits the reaction [Dietary Fats results in increased expression of GPAM mRNA] CTD PMID:21971952 Gpam Rat glycidol decreases expression EXP 6480464 glycidol results in decreased expression of GPAM mRNA CTD PMID:24915197 Gpam Rat GW 6471 multiple interactions ISO GPAM (Homo sapiens) 6480464 GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein] and GW 6471 inhibits the reaction [Dibutyl Phthalate results in increased expression of GPAM protein] CTD PMID:33508418 Gpam Rat hexadecanoic acid increases expression ISO Gpam (Mus musculus) 6480464 Palmitic Acid results in increased expression of GPAM mRNA CTD PMID:29414781 Gpam Rat hydrogen peroxide affects expression ISO GPAM (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of GPAM mRNA CTD PMID:21179406 Gpam Rat indometacin multiple interactions ISO GPAM (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of GPAM mRNA CTD PMID:28628672 Gpam Rat iron atom increases expression EXP 6480464 Iron deficiency results in increased expression of GPAM mRNA CTD PMID:16629162 Gpam Rat iron(0) increases expression EXP 6480464 Iron deficiency results in increased expression of GPAM mRNA CTD PMID:16629162 Gpam Rat isoprenaline decreases expression ISO Gpam (Mus musculus) 6480464 Isoproterenol results in decreased expression of GPAM mRNA CTD PMID:21335049 Gpam Rat ketoconazole decreases expression EXP 6480464 Ketoconazole results in decreased expression of GPAM mRNA CTD PMID:37077353 Gpam Rat L-methionine multiple interactions ISO Gpam (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GPAM gene CTD PMID:20938992 Gpam Rat lead(0) increases expression ISO Gpam (Mus musculus) 6480464 Lead results in increased expression of GPAM mRNA CTD PMID:29529432 Gpam Rat lipopolysaccharide decreases expression ISO Gpam (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of GPAM mRNA CTD PMID:16847310 Gpam Rat metformin increases expression EXP 6480464 Metformin results in increased expression of GPAM mRNA CTD PMID:31324951 Gpam Rat methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of GPAM mRNA CTD PMID:30467583 Gpam Rat methotrexate increases expression ISO GPAM (Homo sapiens) 6480464 Methotrexate results in increased expression of GPAM mRNA CTD PMID:17400583 Gpam Rat methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of GPAM gene CTD PMID:35440735 Gpam Rat microcystin-LR increases expression ISO Gpam (Mus musculus) 6480464 cyanoginosin LR results in increased expression of GPAM protein CTD PMID:26984711 Gpam Rat Muraglitazar increases expression EXP 6480464 muraglitazar results in increased expression of GPAM mRNA CTD PMID:21515302 Gpam Rat N,N-diethyl-m-toluamide multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in decreased methylation of GPAM gene CTD PMID:33148267 Gpam Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GPAM mRNA CTD PMID:18164116 Gpam Rat nickel atom decreases expression ISO GPAM (Homo sapiens) 6480464 Nickel results in decreased expression of GPAM mRNA CTD PMID:24768652 and PMID:25583101 Gpam Rat nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of GPAM mRNA CTD PMID:24136188 Gpam Rat nordihydroguaiaretic acid decreases expression EXP 329955565 NDGA decreases expression of mRNA in liver of high fructose fed rats RGD Gpam Rat O-methyleugenol decreases expression ISO GPAM (Homo sapiens) 6480464 methyleugenol results in decreased expression of GPAM mRNA CTD PMID:32234424 Gpam Rat obeticholic acid decreases expression ISO GPAM (Homo sapiens) 6480464 obeticholic acid results in decreased expression of GPAM mRNA CTD PMID:27939613 Gpam Rat oleic acid multiple interactions ISO GPAM (Homo sapiens) 6480464 [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein more ... CTD PMID:33508418 Gpam Rat oxycodone increases expression EXP 6480464 Oxycodone results in increased expression of GPAM mRNA CTD PMID:23439660 Gpam Rat paracetamol increases expression ISO Gpam (Mus musculus) 6480464 Acetaminophen results in increased expression of GPAM mRNA CTD PMID:11264010 Gpam Rat paracetamol decreases expression ISO GPAM (Homo sapiens) 6480464 Acetaminophen results in decreased expression of GPAM mRNA CTD PMID:21420995 more ... Gpam Rat paracetamol affects expression ISO Gpam (Mus musculus) 6480464 Acetaminophen affects the expression of GPAM mRNA CTD PMID:17562736 Gpam Rat perfluorobutanesulfonic acid increases expression ISO GPAM (Homo sapiens) 6480464 perfluorobutanesulfonic acid results in increased expression of GPAM mRNA CTD PMID:35337807 Gpam Rat perfluorobutyric acid increases expression ISO GPAM (Homo sapiens) 6480464 perfluorobutyric acid results in increased expression of GPAM mRNA CTD PMID:35337807 Gpam Rat perfluorodecanoic acid increases expression ISO GPAM (Homo sapiens) 6480464 perfluorodecanoic acid results in increased expression of GPAM mRNA CTD PMID:35337807 Gpam Rat perfluorododecanoic acid increases expression ISO GPAM (Homo sapiens) 6480464 perfluorododecanoic acid results in increased expression of GPAM mRNA CTD PMID:35337807 Gpam Rat perfluorohexanoic acid increases expression ISO GPAM (Homo sapiens) 6480464 perfluorohexanoic acid results in increased expression of GPAM mRNA CTD PMID:35337807 Gpam Rat perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of GPAM mRNA CTD PMID:21723365 Gpam Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Gpam (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GPAM mRNA CTD PMID:36331819 Gpam Rat perfluorooctane-1-sulfonic acid decreases expression ISO GPAM (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of GPAM mRNA CTD PMID:32588087 Gpam Rat perfluorooctanesulfonamide increases expression ISO GPAM (Homo sapiens) 6480464 perfluorooctanesulfonamide analog results in increased expression of GPAM mRNA and perfluorooctanesulfonamide results in increased expression of GPAM mRNA CTD PMID:35337807 Gpam Rat perfluorooctanoic acid increases expression ISO Gpam (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of GPAM mRNA CTD PMID:17681415 Gpam Rat perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of GPAM mRNA CTD PMID:21723365 Gpam Rat perfluoropentanoic acid increases expression ISO GPAM (Homo sapiens) 6480464 perfluoropentanoic acid results in increased expression of GPAM mRNA CTD PMID:35337807 Gpam Rat perfluoroundecanoic acid increases expression ISO GPAM (Homo sapiens) 6480464 perfluoroundecanoic acid results in increased expression of GPAM mRNA CTD PMID:35337807 Gpam Rat permethrin multiple interactions EXP 6480464 [Permethrin co-treated with DEET] results in decreased methylation of GPAM gene CTD PMID:33148267 Gpam Rat phenformin increases expression EXP 6480464 Phenformin results in increased expression of GPAM mRNA CTD PMID:31324951 Gpam Rat phenobarbital increases expression ISO Gpam (Mus musculus) 6480464 Phenobarbital results in increased expression of GPAM mRNA CTD PMID:19270015 Gpam Rat pirinixic acid multiple interactions ISO Gpam (Mus musculus) 6480464 ACAA1B protein inhibits the reaction [pirinixic acid results in increased expression of GPAM mRNA] and PPARA protein affects the reaction [pirinixic acid results in increased expression of GPAM mRNA] CTD PMID:15777286 and PMID:19772884 Gpam Rat pirinixic acid increases expression ISO Gpam (Mus musculus) 6480464 pirinixic acid results in increased expression of GPAM mRNA CTD PMID:11798191 more ... Gpam Rat pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of GPAM mRNA CTD PMID:19162173 Gpam Rat pregnenolone 16alpha-carbonitrile decreases expression ISO Gpam (Mus musculus) 6480464 Pregnenolone Carbonitrile results in decreased expression of GPAM mRNA CTD PMID:28903501 Gpam Rat procymidone multiple interactions ISO Gpam (Mus musculus) 6480464 [procymidone co-treated with tetrachloroisophthalonitrile] results in decreased expression of GPAM mRNA CTD PMID:33246813 Gpam Rat procymidone increases expression ISO Gpam (Mus musculus) 6480464 procymidone results in increased expression of GPAM mRNA CTD PMID:36764477 Gpam Rat procymidone decreases expression ISO Gpam (Mus musculus) 6480464 procymidone results in decreased expression of GPAM mRNA CTD PMID:33246813 Gpam Rat propamocarb decreases expression ISO Gpam (Mus musculus) 6480464 propamocarb results in decreased expression of GPAM mRNA CTD PMID:29137890 Gpam Rat quercetin decreases expression ISO GPAM (Homo sapiens) 6480464 Quercetin results in decreased expression of GPAM mRNA CTD PMID:21632981 Gpam Rat quercetin multiple interactions ISO Gpam (Mus musculus) 6480464 Quercetin inhibits the reaction [Dietary Fats results in increased expression of GPAM mRNA] CTD PMID:22447684 Gpam Rat resveratrol multiple interactions ISO Gpam (Mus musculus) 6480464 resveratrol inhibits the reaction [Ethanol results in increased expression of GPAM mRNA] CTD PMID:18755807 Gpam Rat resveratrol decreases expression ISO Gpam (Mus musculus) 6480464 resveratrol results in decreased expression of GPAM mRNA CTD PMID:18755807 Gpam Rat rotenone decreases expression ISO Gpam (Mus musculus) 6480464 Rotenone results in decreased expression of GPAM mRNA CTD PMID:17702527 Gpam Rat rotenone affects expression EXP 6480464 Rotenone affects the expression of GPAM mRNA CTD PMID:28374803 Gpam Rat serpentine asbestos decreases expression ISO GPAM (Homo sapiens) 6480464 Asbestos and Serpentine results in decreased expression of GPAM mRNA CTD PMID:24160326 Gpam Rat sevoflurane affects expression EXP 6480464 sevoflurane affects the expression of GPAM mRNA CTD PMID:15967596 Gpam Rat sodium arsenite decreases expression ISO Gpam (Mus musculus) 6480464 sodium arsenite results in decreased expression of GPAM mRNA and sodium arsenite results in decreased expression of GPAM protein CTD PMID:22700541 more ... Gpam Rat sodium arsenite decreases expression ISO GPAM (Homo sapiens) 6480464 sodium arsenite results in decreased expression of GPAM mRNA CTD PMID:29301061 and PMID:38568856 Gpam Rat steviol multiple interactions ISO Gpam (Mus musculus) 6480464 steviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of GPAM mRNA] CTD PMID:25554529 Gpam Rat sucrose multiple interactions ISO Gpam (Mus musculus) 6480464 [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Atrazine] results in increased expression of GPAM mRNA and [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Ethinyl Estradiol] results in increased expression of GPAM mRNA CTD PMID:24440342 Gpam Rat sulfluramid increases expression ISO GPAM (Homo sapiens) 6480464 sulfluramid results in increased expression of GPAM mRNA CTD PMID:35337807 Gpam Rat sunitinib increases expression ISO GPAM (Homo sapiens) 6480464 Sunitinib results in increased expression of GPAM mRNA CTD PMID:31533062 Gpam Rat tectoridin multiple interactions ISO Gpam (Mus musculus) 6480464 tectoridin inhibits the reaction [Ethanol results in increased expression of GPAM mRNA] CTD PMID:20637825 Gpam Rat Tesaglitazar increases expression EXP 6480464 tesaglitazar results in increased expression of GPAM mRNA CTD PMID:21515302 Gpam Rat testosterone increases expression ISO GPAM (Homo sapiens) 6480464 Testosterone results in increased expression of GPAM mRNA CTD PMID:33359661 Gpam Rat tetrachloroethene increases expression ISO Gpam (Mus musculus) 6480464 Tetrachloroethylene results in increased expression of GPAM mRNA CTD PMID:28973375 Gpam Rat tetrachloromethane affects expression ISO Gpam (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of GPAM mRNA CTD PMID:17484886 Gpam Rat tetrachloromethane decreases expression ISO Gpam (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of GPAM mRNA CTD PMID:31919559 Gpam Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of GPAM mRNA CTD PMID:31150632 Gpam Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of GPAM mRNA] CTD PMID:31150632 Gpam Rat thiram increases expression ISO GPAM (Homo sapiens) 6480464 Thiram results in increased expression of GPAM mRNA CTD PMID:38568856 Gpam Rat titanium dioxide decreases expression ISO Gpam (Mus musculus) 6480464 titanium dioxide results in decreased expression of GPAM mRNA CTD PMID:23557971 and PMID:35295148 Gpam Rat titanium dioxide decreases methylation ISO Gpam (Mus musculus) 6480464 titanium dioxide results in decreased methylation of GPAM promoter CTD PMID:35295148 Gpam Rat topiramate decreases expression EXP 6480464 topiramate results in decreased expression of GPAM mRNA CTD PMID:16979414 Gpam Rat trimellitic anhydride increases expression ISO Gpam (Mus musculus) 6480464 trimellitic anhydride results in increased expression of GPAM mRNA CTD PMID:19042947 Gpam Rat triphenyl phosphate affects expression ISO GPAM (Homo sapiens) 6480464 triphenyl phosphate affects the expression of GPAM mRNA CTD PMID:37042841 Gpam Rat troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of GPAM mRNA CTD PMID:9452481 Gpam Rat troglitazone decreases expression ISO GPAM (Homo sapiens) 6480464 troglitazone results in decreased expression of GPAM mRNA CTD PMID:25572481 Gpam Rat trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of GPAM mRNA CTD PMID:24136188 Gpam Rat urethane decreases expression ISO GPAM (Homo sapiens) 6480464 Urethane results in decreased expression of GPAM mRNA CTD PMID:28818685 Gpam Rat valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of GPAM mRNA CTD PMID:24136188 Gpam Rat valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of GPAM mRNA CTD PMID:19224547 Gpam Rat valproic acid affects methylation ISO GPAM (Homo sapiens) 6480464 Valproic Acid affects the methylation of GPAM gene CTD PMID:29501571 Gpam Rat valproic acid affects expression ISO GPAM (Homo sapiens) 6480464 Valproic Acid affects the expression of GPAM mRNA CTD PMID:25979313 Gpam Rat valproic acid decreases expression ISO GPAM (Homo sapiens) 6480464 Valproic Acid results in decreased expression of GPAM mRNA CTD PMID:23179753 and PMID:29501571 Gpam Rat valproic acid increases expression ISO Gpam (Mus musculus) 6480464 Valproic Acid results in increased expression of GPAM mRNA CTD PMID:24489787 Gpam Rat valproic acid affects expression ISO Gpam (Mus musculus) 6480464 Valproic Acid affects the expression of GPAM mRNA CTD PMID:17292431 Gpam Rat vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of GPAM mRNA CTD PMID:23034163 Gpam Rat zinc atom affects expression EXP 6480464 Zinc affects the expression of GPAM mRNA CTD PMID:17181878 Gpam Rat zinc atom decreases expression ISO Gpam (Mus musculus) 6480464 Zinc deficiency results in decreased expression of GPAM mRNA CTD PMID:24155903 Gpam Rat zinc atom multiple interactions ISO Gpam (Mus musculus) 6480464 [Zinc deficiency co-treated with Ethanol] results in decreased expression of GPAM mRNA CTD PMID:24155903 Gpam Rat zinc(0) affects expression EXP 6480464 Zinc affects the expression of GPAM mRNA CTD PMID:17181878 Gpam Rat zinc(0) multiple interactions ISO Gpam (Mus musculus) 6480464 [Zinc deficiency co-treated with Ethanol] results in decreased expression of GPAM mRNA CTD PMID:24155903 Gpam Rat zinc(0) decreases expression ISO Gpam (Mus musculus) 6480464 Zinc deficiency results in decreased expression of GPAM mRNA CTD PMID:24155903
Imported Annotations - SMPDB
Imported Annotations - KEGG (archival)
(+)-catechin (EXP,ISO) (+)-dexrazoxane (ISO) (+)-schisandrin B (EXP) (-)-epigallocatechin 3-gallate (EXP) (1->4)-beta-D-glucan (ISO) 1,2-dimethylhydrazine (ISO) 1-naphthyl isothiocyanate (EXP) 17alpha-ethynylestradiol (EXP,ISO) 17beta-estradiol (EXP,ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dinitrotoluene (EXP) 2-methylcholine (ISO) 3,3',4,4',5-pentachlorobiphenyl (EXP) 3,4-methylenedioxymethamphetamine (ISO) 3-isobutyl-1-methyl-7H-xanthine (ISO) 4,4'-diaminodiphenylmethane (EXP) 4,4'-sulfonyldiphenol (ISO) 4-hydroxyphenyl retinamide (ISO) 6-propyl-2-thiouracil (EXP) acadesine (ISO) aflatoxin B1 (ISO) aldrin (ISO) all-trans-retinoic acid (ISO) amiodarone (EXP) ammonium chloride (EXP) Aroclor 1254 (EXP) atorvastatin calcium (EXP) atrazine (ISO) benzo[a]pyrene (ISO) benzo[a]pyrene diol epoxide I (ISO) benzylpenicillin (ISO) beta-naphthoflavone (EXP) bezafibrate (ISO) bisphenol A (EXP,ISO) bisphenol AF (ISO) Bisphenol B (ISO) bisphenol F (ISO) bromuconazole (EXP) buspirone (EXP) cadmium atom (EXP) cadmium dichloride (EXP,ISO) caffeine (ISO) carbon nanotube (ISO) chloroethene (ISO) chlorothalonil (ISO) chlorpyrifos (ISO) cholesterol (ISO) choline (ISO) clofibrate (EXP) copper(II) sulfate (ISO) coumarin (ISO) crocidolite asbestos (ISO) curcumin (EXP,ISO) cyclosporin A (ISO) decabromodiphenyl ether (EXP) dexamethasone (ISO) dibutyl phthalate (EXP,ISO) dichloroacetic acid (ISO) diethylstilbestrol (EXP) dioxygen (ISO) doxorubicin (ISO) endosulfan (EXP) entacapone (ISO) epoxiconazole (ISO) erythromycin A (ISO) ethanol (ISO) fenofibrate (EXP) fentin chloride (EXP) flutamide (ISO) folic acid (EXP,ISO) FR900359 (ISO) fructose (EXP) fulvestrant (ISO) fumonisin B1 (ISO) genistein (ISO) gentamycin (EXP) ginsenoside Re (ISO) glycidol (EXP) GW 6471 (ISO) hexadecanoic acid (ISO) hydrogen peroxide (ISO) indometacin (ISO) iron atom (EXP) iron(0) (EXP) isoprenaline (ISO) ketoconazole (EXP) L-methionine (ISO) lead(0) (ISO) lipopolysaccharide (ISO) metformin (EXP) methapyrilene (EXP) methotrexate (ISO) methoxychlor (EXP) microcystin-LR (ISO) Muraglitazar (EXP) N,N-diethyl-m-toluamide (EXP) N-nitrosodiethylamine (EXP) nickel atom (ISO) nimesulide (EXP) nordihydroguaiaretic acid (EXP) O-methyleugenol (ISO) obeticholic acid (ISO) oleic acid (ISO) oxycodone (EXP) paracetamol (ISO) perfluorobutanesulfonic acid (ISO) perfluorobutyric acid (ISO) perfluorodecanoic acid (ISO) perfluorododecanoic acid (ISO) perfluorohexanoic acid (ISO) perfluorooctane-1-sulfonic acid (EXP,ISO) perfluorooctanesulfonamide (ISO) perfluorooctanoic acid (EXP,ISO) perfluoropentanoic acid (ISO) perfluoroundecanoic acid (ISO) permethrin (EXP) phenformin (EXP) phenobarbital (ISO) pirinixic acid (EXP,ISO) pregnenolone 16alpha-carbonitrile (ISO) procymidone (ISO) propamocarb (ISO) quercetin (ISO) resveratrol (ISO) rotenone (EXP,ISO) serpentine asbestos (ISO) sevoflurane (EXP) sodium arsenite (ISO) steviol (ISO) sucrose (ISO) sulfluramid (ISO) sunitinib (ISO) tectoridin (ISO) Tesaglitazar (EXP) testosterone (ISO) tetrachloroethene (ISO) tetrachloromethane (EXP,ISO) thiram (ISO) titanium dioxide (ISO) topiramate (EXP) trimellitic anhydride (ISO) triphenyl phosphate (ISO) troglitazone (EXP,ISO) trovafloxacin (EXP) urethane (ISO) valdecoxib (EXP) valproic acid (EXP,ISO) vinclozolin (EXP) zinc atom (EXP,ISO) zinc(0) (EXP,ISO)
Biological Process
activated T cell proliferation (IEA,ISO) activation-induced cell death of T cells (IEA,ISO) acyl-CoA metabolic process (IEA,ISO) CDP-diacylglycerol biosynthetic process (IEA) cellular response to insulin stimulus (IDA) defense response to virus (IEA,ISO) diacylglycerol biosynthetic process (IMP) fatty acid homeostasis (IEA,ISO) fatty acid metabolic process (IEA,ISO) glycerophospholipid metabolic process (IBA,ISO) negative regulation of activation-induced cell death of T cells (IEA,ISO) phosphatidic acid biosynthetic process (IMP) phosphatidylglycerol biosynthetic process (IEA,ISO,ISS) phospholipid homeostasis (IEA,ISO) positive regulation of activated T cell proliferation (IEA,ISO) positive regulation of multicellular organism growth (IEA,ISO) positive regulation of triglyceride biosynthetic process (IDA) regulation of cytokine production (IEA,ISO) response to activity (IDA) response to cadmium ion (IEP) response to fructose (IEP) response to glucose (IEA,ISO) response to nutrient (IEP) response to nutrient levels (IEP) triglyceride biosynthetic process (IBA,IEA,ISO) triglyceride metabolic process (ISO)
1.
Effects of chronic exposure to cadmium on prostate lipids and morphology.
Alvarez SM, etal., Biometals. 2007 Oct;20(5):727-41. Epub 2006 Oct 26.
2.
Acute effects of insulin on the activity of mitochondrial GPAT1 in primary adipocytes.
Bronnikov GE, etal., Biochem Biophys Res Commun. 2008 Feb 29;367(1):201-7. Epub 2007 Dec 31.
3.
Glycerol-3-phosphate acyltransferase-2 is expressed in spermatic germ cells and incorporates arachidonic acid into triacylglycerols.
Cattaneo ER, etal., PLoS One. 2012;7(8):e42986. doi: 10.1371/journal.pone.0042986. Epub 2012 Aug 8.
4.
Rat sn-glycerol-3-phosphate acyltransferase: molecular cloning and characterization of the cDNA and expressed protein.
Ganesh Bhat B, etal., Biochim Biophys Acta 1999 Aug 18;1439(3):415-23.
5.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6.
KEGG: Kyoto Encyclopedia of Genes and Genomes
KEGG
7.
Increased mitochondrial glycerol-3-phosphate acyltransferase protein and enzyme activity in rat epididymal fat upon cessation of wheel running.
Kump DS, etal., Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E480-9. Epub 2005 Oct 18.
8.
Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM.
Lee Y, etal., Diabetes. 1997 Mar;46(3):408-13.
9.
Mitochondrial glycerol-3-phosphate acyltransferase-1 directs the metabolic fate of exogenous fatty acids in hepatocytes.
Lewin TM, etal., Am J Physiol Endocrinol Metab. 2005 May;288(5):E835-44. Epub 2004 Dec 14.
10.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
11.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
12.
Casein kinase II stimulates rat liver mitochondrial glycerophosphate acyltransferase activity.
Onorato TM and Haldar D, Biochem Biophys Res Commun 2002 Sep 6;296(5):1091-6.
13.
Sequential changes in the expression of genes involved in lipid metabolism in adipose tissue and liver in response to fasting.
Palou M, etal., Pflugers Arch. 2008 Aug;456(5):825-36. Epub 2008 May 21.
14.
Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise.
Park H, etal., J Biol Chem 2002 Sep 6;277(36):32571-7.
15.
Mitochondrial glycerol-3-P acyltransferase 1 is most active in outer mitochondrial membrane but not in mitochondrial associated vesicles (MAV).
Pellon-Maison M, etal., Biochim Biophys Acta. 2007 Jul;1771(7):830-8. Epub 2007 Apr 10.
16.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
17.
SMPDB Annotation Import Pipeline
Pipeline to import SMPDB annotations from SMPDB into RGD
18.
GOA pipeline
RGD automated data pipeline
19.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
20.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
21.
Atorvastatin prevents carbohydrate response element binding protein activation in the fructose-fed rat by activating protein kinase A.
Rodriguez-Calvo R, etal., Hepatology. 2009 Jan;49(1):106-15.
22.
Tentative Sequence Identification Numbers
Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
23.
Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis.
Zhang H, etal., PLoS One. 2015 Sep 22;10(9):e0138203. doi: 10.1371/journal.pone.0138203. eCollection 2015.
24.
Expression profiling of hepatic genes associated with lipid metabolism in nephrotic rats.
Zhou Y, etal., Am J Physiol Renal Physiol. 2008 Sep;295(3):F662-71. Epub 2008 Jul 9.
Gpam Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 264,111,599 - 264,176,112 (-) NCBI GRCr8 mRatBN7.2 1 254,106,323 - 254,170,755 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 254,106,331 - 254,142,639 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 262,315,818 - 262,376,481 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 269,021,904 - 269,082,569 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 261,664,129 - 261,730,618 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 275,843,823 - 275,906,880 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 275,846,819 - 275,906,686 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 283,246,186 - 283,309,245 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 261,370,264 - 261,431,434 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 261,581,308 - 261,642,479 (-) NCBI Celera 1 249,818,009 - 249,877,839 (-) NCBI Celera Cytogenetic Map 1 q55 NCBI
GPAM Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 10 112,149,865 - 112,227,677 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 10 112,149,865 - 112,215,377 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 10 113,909,623 - 113,943,523 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 10 113,899,612 - 113,933,508 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 10 113,899,611 - 113,933,508 NCBI Celera 10 107,637,183 - 107,671,081 (-) NCBI Celera Cytogenetic Map 10 q25.2 NCBI HuRef 10 107,537,900 - 107,571,823 (-) NCBI HuRef CHM1_1 10 114,191,437 - 114,225,332 (-) NCBI CHM1_1 T2T-CHM13v2.0 10 113,040,886 - 113,118,691 (-) NCBI T2T-CHM13v2.0
Gpam Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 19 55,056,067 - 55,115,666 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 19 55,055,700 - 55,115,670 (-) Ensembl GRCm39 Ensembl GRCm38 19 55,067,635 - 55,127,319 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 19 55,067,268 - 55,127,238 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 19 55,144,224 - 55,173,937 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 19 55,122,984 - 55,152,703 (-) NCBI MGSCv36 mm8 Celera 19 57,260,690 - 57,290,402 (-) NCBI Celera Cytogenetic Map 19 D2 NCBI cM Map 19 50.81 NCBI
Gpam Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955431 17,291,270 - 17,363,714 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955431 17,291,890 - 17,363,611 (-) NCBI ChiLan1.0 ChiLan1.0
GPAM Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 8 124,031,551 - 124,065,468 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 10 124,036,887 - 124,070,804 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 10 108,747,370 - 108,781,270 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 10 112,186,744 - 112,246,549 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 10 112,186,744 - 112,246,549 (-) Ensembl panpan1.1 panPan2
GPAM Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 28 23,261,673 - 23,323,985 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 28 23,258,428 - 23,298,017 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 28 23,413,452 - 23,450,047 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 28 23,793,834 - 23,830,470 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 28 23,793,834 - 23,830,650 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 28 23,351,250 - 23,387,551 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 28 23,362,221 - 23,398,810 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 28 23,557,678 - 23,594,318 (-) NCBI UU_Cfam_GSD_1.0
Gpam Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024407213 22,737,594 - 22,806,520 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936486 2,754,751 - 2,823,665 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936486 2,754,753 - 2,823,600 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
GPAM Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 14 122,538,491 - 122,579,436 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 14 122,538,600 - 122,582,390 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 14 133,473,315 - 133,545,241 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
GPAM Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 9 105,049,954 - 105,083,750 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 9 105,049,711 - 105,113,374 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666048 66,253,108 - 66,316,689 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Gpam
.
Predicted Target Of
Count of predictions: 117 Count of miRNA genes: 99 Interacting mature miRNAs: 109 Transcripts: ENSRNOT00000047903 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
1354580 Scort1 Serum corticosterone level QTL 1 3.4 blood corticosterone amount (VT:0005345) blood corticosterone level (CMO:0001172) 1 156677124 256448636 Rat 634313 Niddm43 Non-insulin dependent diabetes mellitus QTL 43 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 199050459 259647894 Rat 1549910 Bw54 Body weight QTL 54 0.05 body mass (VT:0001259) body weight (CMO:0000012) 1 214647894 259647894 Rat 1354646 Kidm18 Kidney mass QTL 18 5.7 kidney mass (VT:0002707) calculated kidney weight (CMO:0000160) 1 151162512 256448636 Rat 70211 Niddm24 Non-insulin dependent diabetes mellitus QTL 24 3.79 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 1 214647894 259647894 Rat 724552 Glom2 Glomerulus QTL 2 3.3 0.0001 kidney glomerulus morphology trait (VT:0005325) count of superficial glomeruli directly contacting the kidney surface (CMO:0001001) 1 222363780 260522016 Rat 631690 Scl5 Serum cholesterol level QTL 5 2.1 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 1 236125214 260522016 Rat 1354652 Kidm20 Kidney mass QTL 20 4.3 kidney mass (VT:0002707) calculated kidney weight (CMO:0000160) 1 177227632 256448636 Rat 10053715 Scort24 Serum corticosterone level QTL 24 2.13 0.0088 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 1 221414816 260522016 Rat 61327 Eae7 Experimental allergic encephalomyelitis QTL 7 5.6 body mass (VT:0001259) change in body weight (CMO:0002045) 1 216255568 260522016 Rat 1600392 Bw123 Body weight QTL 123 0.001 body mass (VT:0001259) body weight (CMO:0000012) 1 223201027 260522016 Rat 1578763 Kidm29 Kidney mass QTL 29 3.3 0.0001 kidney mass (VT:0002707) both kidneys wet weight (CMO:0000085) 1 179567751 260522016 Rat 1600395 Niddm69 Non-insulin dependent diabetes mellitus QTL 69 4.14 0.0002 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 1 195804352 257091168 Rat 1354624 Cm35 Cardiac mass QTL35 5.7 heart left ventricle mass (VT:0007031) calculated heart weight (CMO:0000073) 1 177227632 256448636 Rat 1600396 Niddm68 Non-insulin dependent diabetes mellitus QTL 68 4.97 0.0003 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 1 195804352 257091168 Rat 631837 Niddm35 Non-insulin dependent diabetes mellitus QTL 35 0.01 blood insulin amount (VT:0001560) serum insulin level (CMO:0000358) 1 238699859 259647894 Rat 631836 Stl31 Serum triglyceride level QTL 31 4.64 5e-06 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 1 237147813 260522016 Rat 1549837 Hcar15 Hepatocarcinoma resistance QTL 15 0.05 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 1 153136852 260522016 Rat 1600388 Niddm67 Non-insulin dependent diabetes mellitus QTL 67 5.84 0.000004 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 1 195804352 257091168 Rat 1300108 Rf8 Renal function QTL 8 3.75 renal blood flow trait (VT:2000006) absolute change in renal vascular resistance (CMO:0001900) 1 228581588 259647894 Rat 734767 Niddm57 Non-insulin dependent diabetes mellitus QTL 57 body mass (VT:0001259) body weight (CMO:0000012) 1 224054293 260122809 Rat 1354610 Bw34 Body weight QTL 34 4.1 body mass (VT:0001259) body weight (CMO:0000012) 1 151162512 256448636 Rat 631215 Stl8 Serum triglyceride level QTL 8 9.27 0.0001 blood triglyceride amount (VT:0002644) serum triglyceride level (CMO:0000360) 1 225126575 260522016 Rat 7387289 Uae45 Urinary albumin excretion QTL 45 2.86 0.0021 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 1 223262787 260522016 Rat 631843 Bw116 Body weight QTL 116 4.1 0.016 abdominal adipose amount (VT:1000220) abdominal fat pad weight (CMO:0000088) 1 224054293 260122809 Rat 731175 Uae20 Urinary albumin excretion QTL 20 3.5 0.0018 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 1 221264111 259647894 Rat 1598839 Rf56 Renal function QTL 56 renal blood flow trait (VT:2000006) ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239) 1 245907761 257976495 Rat 1581544 Rf52 Renal function QTL 52 0.05 urine total protein amount (VT:0000032) urine protein excretion rate to body weight ratio (CMO:0001099) 1 232156370 259647894 Rat 1354661 Bw33 Body weight QTL 33 5.2 body mass (VT:0001259) body weight (CMO:0000012) 1 151162512 256448636 Rat 631536 Lnnr2 Liver neoplastic nodule remodeling QTL 2 2.9 0.0005 liver integrity trait (VT:0010547) liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705) 1 233948574 260522016 Rat 734769 Niddm58 Non-insulin dependent diabetes mellitus QTL 58 body mass (VT:0001259) body weight (CMO:0000012) 1 224569538 260122809 Rat 738032 Hcas5 Hepatocarcinoma susceptibility QTL 5 3.12 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 1 176426412 257976495 Rat 734768 Niddm59 Non-insulin dependent diabetes mellitus QTL 59 body mass (VT:0001259) body weight (CMO:0000012) 1 213843987 258843987 Rat 2302040 Pia35 Pristane induced arthritis QTL 35 3.8 0.001 blood immunoglobulin amount (VT:0002460) serum immunoglobulin G1 level (CMO:0002115) 1 216255568 260522016 Rat 631669 Iddm9 Insulin dependent diabetes mellitus QTL 9 2.8 0.039 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 1 233190394 258625266 Rat 1598821 Rf55 Renal function QTL 55 6.3 renal blood flow trait (VT:2000006) ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239) 1 218748008 257976495 Rat 1358890 Bp259 Blood pressure QTL 259 3.06 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 210702053 260522016 Rat 724533 Rf51 Renal function QTL 51 5.3 0.0002 kidney plasma flow trait (VT:0005524) renal plasma flow (CMO:0001914) 1 218753816 256448513 Rat
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
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25
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Ensembl Acc Id:
ENSRNOT00000047903 ⟹ ENSRNOP00000050050
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl 1 275,846,966 - 275,876,329 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000083215 ⟹ ENSRNOP00000069320
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 1 254,106,331 - 254,142,442 (-) Ensembl Rnor_6.0 Ensembl 1 275,846,819 - 275,882,444 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000092170 ⟹ ENSRNOP00000072382
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 1 254,109,466 - 254,142,639 (-) Ensembl Rnor_6.0 Ensembl 1 275,847,064 - 275,906,686 (-) Ensembl
RefSeq Acc Id:
NM_017274 ⟹ NP_058970
RefSeq Status:
PROVISIONAL
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 264,114,840 - 264,175,911 (-) NCBI mRatBN7.2 1 254,109,564 - 254,170,561 (-) NCBI Rnor_6.0 1 275,847,064 - 275,906,686 (-) NCBI Rnor_5.0 1 283,246,186 - 283,309,245 (-) NCBI RGSC_v3.4 1 261,370,264 - 261,431,434 (-) RGD Celera 1 249,818,009 - 249,877,839 (-) RGD
Sequence:
CACGAATAAGCCTCTGGAGGAGCTGCTGAATCACCCCCGCCCCAGGCTGTCTTCTGAAGCTGTCTGGGGATAGCTTTGCTAATCAACTGACTGGAAATAATTCCAGACACCACATCAAGGATACAGCT
hide sequence
RefSeq Acc Id:
XM_006231625 ⟹ XP_006231687
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 264,111,599 - 264,148,578 (-) NCBI mRatBN7.2 1 254,109,482 - 254,143,111 (-) NCBI Rnor_6.0 1 275,843,823 - 275,878,536 (-) NCBI Rnor_5.0 1 283,246,186 - 283,309,245 (-) NCBI
Sequence:
TCGCCGTAGCGGCTCGGTCACTCAGACACTTCACAACGTTGCCCTTTGCAATCCTTGTCTCCTCATTCTTCCCAAATTCCGCTTGGTCTCACATACAAAAGGGCAAGATCGCGCACAAGTACCTAAAC
hide sequence
RefSeq Acc Id:
XM_006231626 ⟹ XP_006231688
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 264,111,599 - 264,176,111 (-) NCBI mRatBN7.2 1 254,109,482 - 254,170,755 (-) NCBI Rnor_6.0 1 275,843,823 - 275,906,880 (-) NCBI Rnor_5.0 1 283,246,186 - 283,309,245 (-) NCBI
Sequence:
CTCATGCTTTGGAGCTTGCAATTGGCTGACCAAGCTCGGCCTAGCAGGCCTTATCTCTGGCTGT
hide sequence
RefSeq Acc Id:
XM_063287765 ⟹ XP_063143835
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 264,111,599 - 264,176,112 (-) NCBI
RefSeq Acc Id:
NP_058970 ⟸ NM_017274
- UniProtKB:
P97565 (UniProtKB/Swiss-Prot), O35349 (UniProtKB/Swiss-Prot), P97566 (UniProtKB/Swiss-Prot), P97564 (UniProtKB/Swiss-Prot), A0A0G2K2U7 (UniProtKB/TrEMBL)
- Sequence:
MEESSVTIGTIDVSYLPNSSEYSLGRCKHTNEDWVDCGFKPTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATS
hide sequence
RefSeq Acc Id:
XP_006231688 ⟸ XM_006231626
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2K2U7 (UniProtKB/TrEMBL), A0A0G2JV22 (UniProtKB/TrEMBL), A6JHY2 (UniProtKB/TrEMBL)
- Sequence:
MEESSVTIGTIDVSYLPNSSEYSLGRCKHTNEDWVDCGFKPTFFRSATLKWKESLMSRKRPFVG
hide sequence
RefSeq Acc Id:
XP_006231687 ⟸ XM_006231625
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2K2U7 (UniProtKB/TrEMBL), A0A0G2JV22 (UniProtKB/TrEMBL), A6JHY2 (UniProtKB/TrEMBL)
- Sequence:
MEESSVTIGTIDVSYLPNSSEYSLGRCKHTNEDWVDCGFKPTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATS
hide sequence
Ensembl Acc Id:
ENSRNOP00000072382 ⟸ ENSRNOT00000092170
Ensembl Acc Id:
ENSRNOP00000050050 ⟸ ENSRNOT00000047903
Ensembl Acc Id:
ENSRNOP00000069320 ⟸ ENSRNOT00000083215
RefSeq Acc Id:
XP_063143835 ⟸ XM_063287765
- Peptide Label:
isoform X2
- UniProtKB:
A0A0G2K2U7 (UniProtKB/TrEMBL)
RGD ID: 13690999 Promoter ID: EPDNEW_R1520 Type: single initiation site Name: Gpam_2 Description: glycerol-3-phosphate acyltransferase, mitochondrial SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Alternative Promoters: null; see alsoEPDNEW_R1521 Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 1 275,882,460 - 275,882,520 EPDNEW
RGD ID: 13690996 Promoter ID: EPDNEW_R1521 Type: initiation region Name: Gpam_1 Description: glycerol-3-phosphate acyltransferase, mitochondrial SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Alternative Promoters: null; see alsoEPDNEW_R1520 Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 1 275,906,779 - 275,906,839 EPDNEW
BioCyc Gene G2FUF-55350 BioCyc
BioCyc Pathway PWY-5667 [CDP-diacylglycerol biosynthesis I] BioCyc
PWY-7411 [phosphatidate biosynthesis (yeast)] BioCyc
PWY-8053 [anandamide biosynthesis II] BioCyc
TRIGLSYN-PWY [diacylglycerol and triacylglycerol biosynthesis] BioCyc
BioCyc Pathway Image PWY-5667 BioCyc
PWY-7411 BioCyc
PWY-8053 BioCyc
TRIGLSYN-PWY BioCyc
Ensembl Genes ENSRNOG00000015124 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000083215.2 UniProtKB/TrEMBL
ENSRNOT00000092170.2 UniProtKB/TrEMBL
InterPro GPAT/DHAPAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GPAT/DHAPAT_LPLAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GPAT_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GPAT_PlsB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Plipid/glycerol_acylTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29653 UniProtKB/Swiss-Prot
NCBI Gene 29653 ENTREZGENE
PANTHER GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PTHR12563 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GPAT_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gpam PhenoGen
PIRSF GPAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GPAT_DHAPAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015124 RatGTEx
SMART PlsC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glycerol-3-phosphate (1)-acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC235444
UniProt A0A0G2JV22 ENTREZGENE, UniProtKB/TrEMBL
A0A0G2K2U7 ENTREZGENE, UniProtKB/TrEMBL
A6JHY2 ENTREZGENE, UniProtKB/TrEMBL
GPAT1_RAT UniProtKB/Swiss-Prot
O35349 ENTREZGENE
P97564 ENTREZGENE
P97565 ENTREZGENE
P97566 ENTREZGENE
UniProt Secondary O35349 UniProtKB/Swiss-Prot
P97565 UniProtKB/Swiss-Prot
P97566 UniProtKB/Swiss-Prot
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2004-09-10
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
glycerol-3-phosphate acyltransferase, mitochondrial
Name updated
1299863 APPROVED
2002-06-10
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
Name updated
70584 APPROVED
Note Type
Note
Reference
gene_regulation
acyltransferase activity is activated by phosphorylation by casein kinase II
633001
gene_regulation
expression is regulated in liver and adipose tissue by AMP-activated protein kinase in response to exercise
631891
