Fbxl18 (F-box and leucine-rich repeat protein 18) - Rat Genome Database

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Gene: Fbxl18 (F-box and leucine-rich repeat protein 18) Rattus norvegicus
Analyze
Symbol: Fbxl18
Name: F-box and leucine-rich repeat protein 18
RGD ID: 1596958
Description: Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXL18 (F-box and leucine rich repeat protein 18); INTERACTS WITH aflatoxin B1; gentamycin; thioacetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: F-box/LRR-repeat protein 18; LOC678726; similar to F-box and leucine-rich repeat protein 18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,781,901 - 16,812,728 (+)NCBIGRCr8
mRatBN7.21211,674,538 - 11,701,317 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1211,676,115 - 11,699,181 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1212,486,232 - 12,509,267 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01213,109,498 - 13,132,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01212,140,879 - 12,163,832 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01213,728,155 - 13,751,781 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,734,429 - 13,747,215 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01215,758,146 - 15,782,360 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,060,498 - 12,083,885 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1213,465,496 - 13,488,368 (+)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19028597  


Genomics

Comparative Map Data
Fbxl18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,781,901 - 16,812,728 (+)NCBIGRCr8
mRatBN7.21211,674,538 - 11,701,317 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1211,676,115 - 11,699,181 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1212,486,232 - 12,509,267 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01213,109,498 - 13,132,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01212,140,879 - 12,163,832 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01213,728,155 - 13,751,781 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,734,429 - 13,747,215 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01215,758,146 - 15,782,360 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,060,498 - 12,083,885 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1213,465,496 - 13,488,368 (+)NCBICelera
Cytogenetic Map12p11NCBI
FBXL18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3875,454,425 - 5,513,809 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl75,431,335 - 5,513,809 (-)EnsemblGRCh38hg38GRCh38
GRCh3775,494,056 - 5,553,440 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3675,481,954 - 5,519,925 (-)NCBINCBI36Build 36hg18NCBI36
Build 3475,244,206 - 5,326,623NCBI
Celera75,475,728 - 5,513,156 (-)NCBICelera
Cytogenetic Map7p22.1NCBI
HuRef75,428,257 - 5,466,043 (-)NCBIHuRef
CHM1_175,515,012 - 5,552,982 (-)NCBICHM1_1
T2T-CHM13v2.075,571,979 - 5,631,328 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v275,561,782 - 5,599,744 (-)NCBI
Fbxl18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395142,852,701 - 142,882,696 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5142,852,701 - 142,881,176 (-)EnsemblGRCm39 Ensembl
GRCm385142,871,789 - 142,896,721 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5142,866,946 - 142,895,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv375143,633,468 - 143,656,917 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365143,136,929 - 143,160,357 (-)NCBIMGSCv36mm8
Celera5139,920,364 - 139,943,655 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map581.79NCBI
Fbxl18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546010,322,092 - 10,349,225 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546010,318,089 - 10,349,135 (-)NCBIChiLan1.0ChiLan1.0
FBXL18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2610,443,970 - 10,481,285 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1758,768,675 - 58,805,901 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v075,734,703 - 5,770,942 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.175,751,134 - 5,789,134 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl75,751,134 - 5,789,134 (-)Ensemblpanpan1.1panPan2
FBXL18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1612,434,983 - 12,479,702 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl612,435,115 - 12,475,292 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha613,906,887 - 13,972,048 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0612,571,546 - 12,637,508 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl612,571,572 - 12,627,581 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1612,381,597 - 12,448,613 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0612,315,388 - 12,381,379 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0612,592,825 - 12,658,259 (+)NCBIUU_Cfam_GSD_1.0
Fbxl18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344140,688,544 - 140,730,319 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936765679,554 - 721,411 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936765679,643 - 721,379 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXL18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl34,033,580 - 4,079,549 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.134,031,784 - 4,079,605 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.234,686,636 - 4,722,557 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXL18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12816,216,102 - 16,249,262 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2816,216,176 - 16,248,409 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660905,731,900 - 5,766,133 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxl18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474028,098,310 - 28,126,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474028,098,394 - 28,126,181 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fbxl18
96 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12683319017870186Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12931821612829686Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121107382524234895Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat

Markers in Region
UniSTS:488446  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0598,571,378 - 98,571,836NCBIRnor6.0
Rnor_5.05102,616,219 - 102,616,677UniSTSRnor5.0
RGSC_v3.4599,703,070 - 99,704,253UniSTSRGSC3.4
Celera594,034,136 - 94,035,319UniSTS
Cytogenetic Map12p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 23
Low 3 42 57 41 19 41 8 11 51 35 41 11 8
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001479   ⟹   ENSRNOP00000001479
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1211,676,215 - 11,696,620 (+)Ensembl
Rnor_6.0 Ensembl1213,734,429 - 13,747,215 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116118   ⟹   ENSRNOP00000077132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1211,676,115 - 11,699,181 (+)Ensembl
RefSeq Acc Id: NM_001398874   ⟹   NP_001385803
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,789,751 - 16,812,728 (+)NCBI
mRatBN7.21211,676,201 - 11,699,186 (+)NCBI
RefSeq Acc Id: XM_017598486   ⟹   XP_017453975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,781,901 - 16,812,728 (+)NCBI
mRatBN7.21211,674,538 - 11,701,317 (+)NCBI
Rnor_6.01213,728,155 - 13,751,781 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063271648   ⟹   XP_063127718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,781,901 - 16,802,189 (+)NCBI
RefSeq Acc Id: XM_063271649   ⟹   XP_063127719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81216,781,901 - 16,798,608 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001385803 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453975 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127718 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127719 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001479.7
  ENSRNOP00000077132
  ENSRNOP00000077132.1
Reference Protein Sequences
RefSeq Acc Id: XP_017453975   ⟸   XM_017598486
- Peptide Label: isoform X1
- UniProtKB: A0A8I5XVT7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000001479   ⟸   ENSRNOT00000001479
RefSeq Acc Id: ENSRNOP00000077132   ⟸   ENSRNOT00000116118
RefSeq Acc Id: NP_001385803   ⟸   NM_001398874
RefSeq Acc Id: XP_063127718   ⟸   XM_063271648
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063127719   ⟸   XM_063271649
- Peptide Label: isoform X3
Protein Domains
F-box   F-box/LRR-repeat protein 18 LRR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZU50-F1-model_v2 AlphaFold D3ZU50 1-656 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1596958 AgrOrtholog
BioCyc Gene G2FUF-19979 BioCyc
Ensembl Genes ENSRNOG00000001117 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001479.7 UniProtKB/TrEMBL
  ENSRNOT00000116118 ENTREZGENE
  ENSRNOT00000116118.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro F-box_dom UniProtKB/TrEMBL
  F-box_dom_like UniProtKB/TrEMBL
  FBXL18_F-box UniProtKB/TrEMBL
  FBXL18_LRR UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
NCBI Gene 678726 ENTREZGENE
PANTHER F-BOX/LRR-REPEAT PROTEIN 18 UniProtKB/TrEMBL
  F-BOX/TPR REPEAT PROTEIN POF3 UniProtKB/TrEMBL
  FI05230P-RELATED UniProtKB/TrEMBL
  PTHR12904 UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
  FBXL18_C UniProtKB/TrEMBL
PhenoGen Fbxl18 PhenoGen
RatGTEx ENSRNOG00000001117 RatGTEx
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A8I5XVT7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZU50_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Fbxl18  F-box and leucine-rich repeat protein 18  LOC686176  similar to F-box and leucine-rich repeat protein 18  Data merged from RGD:1585426 1643240 APPROVED
2008-03-05 Fbxl18  F-box and leucine-rich repeat protein 18  LOC678726  similar to F-box and leucine-rich repeat protein 18  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC678726  similar to F-box and leucine-rich repeat protein 18      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC686176  similar to F-box and leucine-rich repeat protein 18      Symbol and Name status set to provisional 70820 PROVISIONAL