Fbxl18 (F-box and leucine rich repeat protein 18) - Rat Genome Database

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Gene: Fbxl18 (F-box and leucine rich repeat protein 18) Heterocephalus glaber
Analyze
Symbol: Fbxl18
Name: F-box and leucine rich repeat protein 18
RGD ID: 18910385
Description: INVOLVED IN SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); hepatocellular carcinoma (ortholog); FOUND IN SCF ubiquitin ligase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box/LRR-repeat protein 18
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474028,098,310 - 28,126,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474028,098,394 - 28,126,181 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fbxl18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474028,098,310 - 28,126,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474028,098,394 - 28,126,181 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FBXL18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3875,454,425 - 5,513,809 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl75,431,335 - 5,513,809 (-)EnsemblGRCh38hg38GRCh38
GRCh3775,494,056 - 5,553,440 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3675,481,954 - 5,519,925 (-)NCBINCBI36Build 36hg18NCBI36
Build 3475,244,206 - 5,326,623NCBI
Celera75,475,728 - 5,513,156 (-)NCBICelera
Cytogenetic Map7p22.1NCBI
HuRef75,428,257 - 5,466,043 (-)NCBIHuRef
CHM1_175,515,012 - 5,552,982 (-)NCBICHM1_1
T2T-CHM13v2.075,571,979 - 5,631,328 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v275,561,782 - 5,599,744 (-)NCBI
Fbxl18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395142,852,701 - 142,882,696 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5142,852,701 - 142,881,176 (-)EnsemblGRCm39 Ensembl
GRCm385142,871,789 - 142,896,721 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5142,866,946 - 142,895,421 (-)EnsemblGRCm38mm10GRCm38
MGSCv375143,633,468 - 143,656,917 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365143,136,929 - 143,160,357 (-)NCBIMGSCv36mm8
Celera5139,920,364 - 139,943,655 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map581.79NCBI
Fbxl18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,781,901 - 16,812,728 (+)NCBIGRCr8
mRatBN7.21211,674,538 - 11,701,317 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1211,676,115 - 11,699,181 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1212,486,232 - 12,509,267 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01213,109,498 - 13,132,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01212,140,879 - 12,163,832 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01213,728,155 - 13,751,781 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,734,429 - 13,747,215 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01215,758,146 - 15,782,360 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,060,498 - 12,083,885 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1213,465,496 - 13,488,368 (+)NCBICelera
Cytogenetic Map12p11NCBI
Fbxl18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546010,322,092 - 10,349,225 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546010,318,089 - 10,349,135 (-)NCBIChiLan1.0ChiLan1.0
FBXL18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2610,443,970 - 10,481,285 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1758,768,675 - 58,805,901 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v075,734,703 - 5,770,942 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.175,751,134 - 5,789,134 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl75,751,134 - 5,789,134 (-)Ensemblpanpan1.1panPan2
FBXL18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1612,434,983 - 12,479,702 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl612,435,115 - 12,475,292 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha613,906,887 - 13,972,048 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0612,571,546 - 12,637,508 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl612,571,572 - 12,627,581 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1612,381,597 - 12,448,613 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0612,315,388 - 12,381,379 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0612,592,825 - 12,658,259 (+)NCBIUU_Cfam_GSD_1.0
Fbxl18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344140,688,544 - 140,730,319 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936765679,554 - 721,411 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936765679,643 - 721,379 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXL18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl34,033,580 - 4,079,549 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.134,031,784 - 4,079,605 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.234,686,636 - 4,722,557 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXL18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12816,216,102 - 16,249,262 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2816,216,176 - 16,248,409 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660905,731,900 - 5,766,133 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000007517   ⟹   ENSHGLP00000007432
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474028,098,310 - 28,122,182 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000007518   ⟹   ENSHGLP00000007433
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474028,098,330 - 28,126,454 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000007519   ⟹   ENSHGLP00000007434
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474028,098,397 - 28,126,454 (+)Ensembl
RefSeq Acc Id: XM_004840382   ⟹   XP_004840439
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474028,098,394 - 28,126,181 (+)NCBI
RefSeq Acc Id: XM_004840383   ⟹   XP_004840440
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474028,098,394 - 28,126,181 (+)NCBI
RefSeq Acc Id: XM_021254648   ⟹   XP_021110307
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474028,098,394 - 28,126,181 (+)NCBI
RefSeq Acc Id: XM_021254649   ⟹   XP_021110308
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474028,098,394 - 28,126,181 (+)NCBI
RefSeq Acc Id: XM_021254650   ⟹   XP_021110309
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474028,098,394 - 28,126,181 (+)NCBI
RefSeq Acc Id: XM_021254651   ⟹   XP_021110310
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474028,106,577 - 28,126,181 (+)NCBI
RefSeq Acc Id: XM_021254652   ⟹   XP_021110311
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474028,106,577 - 28,126,181 (+)NCBI
RefSeq Acc Id: XR_002393349
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474028,098,394 - 28,126,181 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004840440   ⟸   XM_004840383
- Peptide Label: isoform X4
- UniProtKB: A0A0P6JBL1 (UniProtKB/TrEMBL),   G5BI77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110308   ⟸   XM_021254649
- Peptide Label: isoform X3
- UniProtKB: G5BI77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110307   ⟸   XM_021254648
- Peptide Label: isoform X1
- UniProtKB: G5BI77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004840439   ⟸   XM_004840382
- Peptide Label: isoform X2
- UniProtKB: G5BI77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110309   ⟸   XM_021254650
- Peptide Label: isoform X4
- UniProtKB: A0A0P6JBL1 (UniProtKB/TrEMBL),   G5BI77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110310   ⟸   XM_021254651
- Peptide Label: isoform X5
- UniProtKB: G5BI77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110311   ⟸   XM_021254652
- Peptide Label: isoform X5
- UniProtKB: G5BI77 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000007432   ⟸   ENSHGLT00000007517
RefSeq Acc Id: ENSHGLP00000007433   ⟸   ENSHGLT00000007518
RefSeq Acc Id: ENSHGLP00000007434   ⟸   ENSHGLT00000007519


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005412 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000007518 ENTREZGENE
  ENSHGLT00000007519 ENTREZGENE
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro F-box-like_dom_sf UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  FBXL18_LRR UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
NCBI Gene Fbxl18 ENTREZGENE
PANTHER JETLAG, ISOFORM A UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
  FBXL18_C UniProtKB/TrEMBL
PROSITE FBOX UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
  SSF81383 UniProtKB/TrEMBL
UniProt A0A0P6JBL1 ENTREZGENE, UniProtKB/TrEMBL
  G5BI77 ENTREZGENE, UniProtKB/TrEMBL