Wdr54 (WD repeat domain 54) - Rat Genome Database

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Gene: Wdr54 (WD repeat domain 54) Rattus norvegicus
Analyze
Symbol: Wdr54
Name: WD repeat domain 54
RGD ID: 1561494
Description: Predicted to enable protein homodimerization activity. Involved in fusion of sperm to egg plasma membrane involved in single fertilization. Located in cytoplasm and plasma membrane. Orthologous to human WDR54 (WD repeat domain 54); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC103692166; LOC500226; RGD1561494; similar to D3Mm3e; WD repeat-containing protein 54
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84117,212,677 - 117,236,456 (-)NCBIGRCr8
mRatBN7.24115,654,968 - 115,677,979 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4115,654,968 - 115,661,562 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4121,131,661 - 121,138,258 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04116,906,844 - 116,913,441 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04115,521,131 - 115,527,714 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04114,847,722 - 114,871,989 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4113,981,653 - 113,988,246 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4114,850,815 - 114,853,868 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04179,436,792 - 179,460,392 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,360,988 - 117,367,581 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4104,649,110 - 104,655,703 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Wdr54Ratcongenital disorder of glycosylation type IIb  ISOWDR54 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital disorder of glycosylation type 2BClinVarPMID:24716661 more ...
Wdr54Ratdystonia  ISOWDR54 (Homo sapiens)8554872ClinVar Annotator: match by term: DystoniaClinVarPMID:16697227 more ...
Wdr54RatMethylmalonyl-CoA Epimerase Deficiency  ISOWDR54 (Homo sapiens)8554872ClinVar Annotator: match by term: METHYLMALONIC ACIDURIA IIIClinVarPMID:16697227 more ...

1 to 20 of 66 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Wdr54Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOWdr54 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of WDR54 mRNACTDPMID:21570461
Wdr54Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of WDR54 mRNACTDPMID:33387578
Wdr54Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOWDR54 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of WDR54 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of WDR54 mRNACTDPMID:28628672
Wdr54Rat4,4'-sulfonyldiphenol multiple interactionsISOWDR54 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of WDR54 mRNACTDPMID:28628672
Wdr54Rat4-hydroxyphenyl retinamide increases expressionISOWdr54 (Mus musculus)6480464Fenretinide results in increased expression of WDR54 mRNACTDPMID:28973697
Wdr54Rat5-aza-2'-deoxycytidine affects expressionISOWDR54 (Homo sapiens)6480464Decitabine affects the expression of WDR54 mRNACTDPMID:23300844
Wdr54Ratacrylamide decreases expressionISOWDR54 (Homo sapiens)6480464Acrylamide results in decreased expression of WDR54 mRNACTDPMID:32763439
Wdr54Rataflatoxin B1 increases expressionEXP 6480464Aflatoxin B1 results in increased expression of WDR54 mRNACTDPMID:23630614
Wdr54Rataflatoxin B1 increases expressionISOWDR54 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of WDR54 mRNACTDPMID:27153756
Wdr54Ratamphetamine increases expressionEXP 6480464Amphetamine results in increased expression of WDR54 mRNACTDPMID:30779732
Wdr54Ratantirheumatic drug decreases expressionISOWDR54 (Homo sapiens)6480464Antirheumatic Agents results in decreased expression of WDR54 mRNACTDPMID:24449571
Wdr54Ratarsenite(3-) multiple interactionsISOWDR54 (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to WDR54 mRNA]CTDPMID:32406909
Wdr54Ratbenzo[a]pyrene increases expressionISOWDR54 (Homo sapiens)6480464Benzo(a)pyrene results in increased expression of WDR54 mRNACTDPMID:22316170
Wdr54Ratbenzo[a]pyrene decreases expressionISOWdr54 (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of WDR54 mRNACTDPMID:22228805
Wdr54Ratbenzo[a]pyrene diol epoxide I increases expressionISOWDR54 (Homo sapiens)64804647 more ...CTDPMID:26238291
Wdr54Ratbeta-lapachone decreases expressionISOWDR54 (Homo sapiens)6480464beta-lapachone results in decreased expression of WDR54 mRNACTDPMID:38218311
Wdr54Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of WDR54 mRNACTDPMID:25181051 and PMID:30816183
Wdr54Ratbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of WDR54 mRNACTDPMID:34947998
Wdr54Ratbisphenol A affects expressionISOWDR54 (Homo sapiens)6480464bisphenol A affects the expression of WDR54 mRNACTDPMID:30903817
Wdr54Ratbisphenol F multiple interactionsISOWDR54 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of WDR54 mRNACTDPMID:28628672

1 to 20 of 66 rows

Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Wdr54Ratcytoplasm located_inIDA 408345208PMID:37951137UniProt 
Wdr54Ratmotile cilium is_active_inIBAPANTHER:PTN000347236 and UniProtKB:Q8TBY91600115GO_REF:0000033GO_CentralGO_REF:0000033
Wdr54Ratplasma membrane located_inIDA 408345208PMID:37951137UniProt 
Wdr54Ratvesicle located_inISOWDR54 (Homo sapiens)1624291 PMID:30458214RGDPMID:30458214

Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Participation of WD repeat-containing protein 54 (WDR54) in rat sperm-oocyte fusion through interaction with both IZUMO1 and JUNO. Lai X, etal., Theriogenology. 2024 Jan 15;214:286-297. doi: 10.1016/j.theriogenology.2023.10.031. Epub 2023 Nov 7.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:30458214  



Wdr54
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84117,212,677 - 117,236,456 (-)NCBIGRCr8
mRatBN7.24115,654,968 - 115,677,979 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4115,654,968 - 115,661,562 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4121,131,661 - 121,138,258 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04116,906,844 - 116,913,441 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04115,521,131 - 115,527,714 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04114,847,722 - 114,871,989 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4113,981,653 - 113,988,246 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4114,850,815 - 114,853,868 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04179,436,792 - 179,460,392 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,360,988 - 117,367,581 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4104,649,110 - 104,655,703 (-)NCBICelera
Cytogenetic Map4q34NCBI
WDR54
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38274,421,730 - 74,425,755 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl274,421,678 - 74,425,755 (+)EnsemblGRCh38hg38GRCh38
GRCh37274,648,857 - 74,652,882 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36274,502,393 - 74,506,390 (+)NCBINCBI36Build 36hg18NCBI36
Build 34274,560,539 - 74,564,536NCBI
Celera274,480,074 - 74,484,071 (+)NCBICelera
Cytogenetic Map2p13.1NCBI
HuRef274,385,197 - 74,389,194 (+)NCBIHuRef
CHM1_1274,578,303 - 74,582,300 (+)NCBICHM1_1
T2T-CHM13v2.0274,430,287 - 74,434,312 (+)NCBIT2T-CHM13v2.0
Wdr54
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,129,691 - 83,133,383 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl683,126,342 - 83,133,379 (-)EnsemblGRCm39 Ensembl
GRCm38683,152,710 - 83,156,524 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,149,361 - 83,156,397 (-)EnsemblGRCm38mm10GRCm38
MGSCv37683,102,704 - 83,106,373 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36683,118,406 - 83,122,025 (-)NCBIMGSCv36mm8
Celera685,135,616 - 85,139,287 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
Wdr54
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542411,358,694 - 11,362,053 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542411,358,694 - 11,362,138 (-)NCBIChiLan1.0ChiLan1.0
WDR54
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21251,963,500 - 51,967,536 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A51,966,253 - 51,970,289 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A74,488,345 - 74,492,392 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A75,994,378 - 75,998,385 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A75,994,394 - 75,998,385 (+)Ensemblpanpan1.1panPan2
WDR54
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11748,700,432 - 48,734,250 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1748,700,431 - 48,704,344 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1748,342,069 - 48,375,651 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01749,559,726 - 49,593,603 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1749,559,725 - 49,563,638 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11748,576,773 - 48,610,446 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01748,643,308 - 48,676,908 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01749,201,309 - 49,235,141 (-)NCBIUU_Cfam_GSD_1.0
Wdr54
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629210,087,698 - 10,091,606 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936556645,933 - 662,452 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936556646,312 - 649,961 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR54
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl368,614,020 - 68,622,598 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1368,614,019 - 68,618,433 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2371,804,660 - 71,809,072 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WDR54
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11432,851,904 - 32,855,918 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1432,851,959 - 32,855,912 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604579,314,481 - 79,318,492 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr54
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474929,076,554 - 29,080,128 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474929,076,668 - 29,080,169 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Wdr54
100 total Variants

Predicted Target Of
Summary Value
Count of predictions:606
Count of miRNA genes:263
Interacting mature miRNAs:352
Transcripts:ENSRNOT00000013128
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 52 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106649412151649412Rat

1 to 10 of 52 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
15 11 45 199 88 83 40 31 40 12 225 111 167 51 80 43



Ensembl Acc Id: ENSRNOT00000013128   ⟹   ENSRNOP00000013128
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4115,654,968 - 115,661,562 (-)Ensembl
Rnor_6.0 Ensembl4113,981,653 - 113,988,246 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090828   ⟹   ENSRNOP00000068651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4114,850,815 - 114,853,868 (-)Ensembl
RefSeq Acc Id: NM_001109245   ⟹   NP_001102715
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,212,677 - 117,219,270 (-)NCBI
mRatBN7.24115,654,968 - 115,661,562 (-)NCBI
Rnor_6.04114,847,722 - 114,854,315 (-)NCBI
Rnor_5.04179,436,792 - 179,460,392 (-)NCBI
RGSC_v3.44117,360,988 - 117,367,581 (-)RGD
Celera4104,649,110 - 104,655,703 (-)RGD
Sequence:
RefSeq Acc Id: XM_006236778   ⟹   XP_006236840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,215,778 - 117,219,279 (-)NCBI
mRatBN7.24115,658,070 - 115,661,587 (-)NCBI
Rnor_6.04114,850,823 - 114,854,306 (-)NCBI
Rnor_5.04179,436,792 - 179,460,392 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006236780   ⟹   XP_006236842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,215,778 - 117,219,317 (-)NCBI
mRatBN7.24115,658,070 - 115,661,598 (-)NCBI
Rnor_6.04114,850,823 - 114,854,325 (-)NCBI
Rnor_5.04179,436,792 - 179,460,392 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006236781   ⟹   XP_006236843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,215,778 - 117,236,456 (-)NCBI
mRatBN7.24115,658,070 - 115,677,979 (-)NCBI
Rnor_6.04114,850,823 - 114,871,989 (-)NCBI
Rnor_5.04179,436,792 - 179,460,392 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039108151   ⟹   XP_038964079
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,215,778 - 117,219,283 (-)NCBI
mRatBN7.24115,658,070 - 115,661,541 (-)NCBI
RefSeq Acc Id: XM_063286524   ⟹   XP_063142594
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84117,215,778 - 117,219,266 (-)NCBI
RefSeq Acc Id: NP_001102715   ⟸   NM_001109245
- UniProtKB: D3ZX63 (UniProtKB/TrEMBL),   A6IAL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236843   ⟸   XM_006236781
- Peptide Label: isoform X1
- UniProtKB: D3ZX63 (UniProtKB/TrEMBL),   A6IAL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236842   ⟸   XM_006236780
- Peptide Label: isoform X1
- UniProtKB: D3ZX63 (UniProtKB/TrEMBL),   A6IAL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236840   ⟸   XM_006236778
- Peptide Label: isoform X1
- UniProtKB: D3ZX63 (UniProtKB/TrEMBL),   A6IAL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038964079   ⟸   XM_039108151
- Peptide Label: isoform X1
- UniProtKB: D3ZX63 (UniProtKB/TrEMBL),   A6IAL0 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZX63-F1-model_v2 AlphaFold D3ZX63 1-334 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-44018 BioCyc
Ensembl Genes ENSRNOG00000009324 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00000060514 Ensembl
  ENSRNOG00055012269 UniProtKB/Swiss-Prot
  ENSRNOG00060002367 UniProtKB/Swiss-Prot
  ENSRNOG00065015803 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000013128.6 UniProtKB/Swiss-Prot
  ENSRNOT00055020876 UniProtKB/Swiss-Prot
  ENSRNOT00060003733 UniProtKB/Swiss-Prot
  ENSRNOT00065026247 UniProtKB/Swiss-Prot
Gene3D-CATH YVTN repeat-like/Quinoprotein amine dehydrogenase UniProtKB/Swiss-Prot
InterPro WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
  WD40_rpt UniProtKB/Swiss-Prot
  WDR54_beta_propeller UniProtKB/Swiss-Prot
KEGG Report rno:500226 UniProtKB/Swiss-Prot
NCBI Gene 500226 ENTREZGENE
Pfam WDR54 UniProtKB/Swiss-Prot
PhenoGen Wdr54 PhenoGen
PROSITE WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009324 RatGTEx
  ENSRNOG00000060514 RatGTEx
  ENSRNOG00055012269 RatGTEx
  ENSRNOG00060002367 RatGTEx
  ENSRNOG00065015803 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP WD40 repeat-like UniProtKB/Swiss-Prot
UniProt A6IAL0 ENTREZGENE
  D3ZX63 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A6IAL0 UniProtKB/Swiss-Prot
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Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Wdr54  WD repeat domain 54  LOC103692166  WD repeat-containing protein 54  Data merged from RGD:9477816 737654 PROVISIONAL
2014-08-25 LOC103692166  WD repeat-containing protein 54      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-23 Wdr54  WD repeat domain 54  RGD1561494  similar to D3Mm3e   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561494  similar to D3Mm3e   RGD1561494_predicted  similar to D3Mm3e (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561494_predicted  similar to D3Mm3e (predicted)  LOC500226  similar to D3Mm3e  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500226  similar to D3Mm3e      Symbol and Name status set to provisional 70820 PROVISIONAL