WDR54 (WD repeat domain 54) - Rat Genome Database

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Gene: WDR54 (WD repeat domain 54) Canis lupus familiaris
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Symbol: WDR54
Name: WD repeat domain 54
RGD ID: 12285719
Description: ENCODES a protein that exhibits protein homodimerization activity (inferred); INVOLVED IN negative regulation of receptor internalization (inferred); regulation of epidermal growth factor receptor signaling pathway (inferred); regulation of MAPK cascade (inferred); FOUND IN vesicle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: WD repeat-containing protein 54
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11748,700,432 - 48,734,250 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1748,700,431 - 48,704,344 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1748,342,069 - 48,375,651 (-)NCBI
ROS_Cfam_1.01749,559,726 - 49,593,603 (-)NCBI
UMICH_Zoey_3.11748,576,773 - 48,610,446 (-)NCBI
UNSW_CanFamBas_1.01748,643,308 - 48,676,908 (-)NCBI
UU_Cfam_GSD_1.01749,201,309 - 49,235,141 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
vesicle  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
WDR54
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11748,700,432 - 48,734,250 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1748,700,431 - 48,704,344 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1748,342,069 - 48,375,651 (-)NCBI
ROS_Cfam_1.01749,559,726 - 49,593,603 (-)NCBI
UMICH_Zoey_3.11748,576,773 - 48,610,446 (-)NCBI
UNSW_CanFamBas_1.01748,643,308 - 48,676,908 (-)NCBI
UU_Cfam_GSD_1.01749,201,309 - 49,235,141 (-)NCBI
WDR54
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl274,421,678 - 74,425,755 (+)EnsemblGRCh38hg38GRCh38
GRCh38274,421,721 - 74,426,259 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37274,648,857 - 74,652,882 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36274,502,393 - 74,506,390 (+)NCBINCBI36hg18NCBI36
Build 34274,560,539 - 74,564,536NCBI
Celera274,480,074 - 74,484,071 (+)NCBI
Cytogenetic Map2p13.1NCBI
HuRef274,385,197 - 74,389,194 (+)NCBIHuRef
CHM1_1274,578,268 - 74,582,300 (+)NCBICHM1_1
Wdr54
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,129,691 - 83,133,383 (-)NCBIGRCm39mm39
GRCm39 Ensembl683,126,342 - 83,133,379 (-)Ensembl
GRCm38683,152,710 - 83,156,524 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,149,361 - 83,156,397 (-)EnsemblGRCm38mm10GRCm38
MGSCv37683,102,704 - 83,106,373 (-)NCBIGRCm37mm9NCBIm37
MGSCv36683,118,406 - 83,122,025 (-)NCBImm8
Celera685,135,616 - 85,139,287 (-)NCBICelera
Cytogenetic Map6C3NCBI
Wdr54
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24115,654,968 - 115,677,979 (-)NCBI
Rnor_6.0 Ensembl4113,981,653 - 113,988,246 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl4114,850,815 - 114,853,868 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04114,847,722 - 114,871,989 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04179,436,792 - 179,460,392 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,360,988 - 117,367,581 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4104,649,110 - 104,655,703 (-)NCBICelera
Cytogenetic Map4q34NCBI
Wdr54
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542411,358,694 - 11,362,053 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542411,358,694 - 11,362,138 (-)NCBIChiLan1.0ChiLan1.0
WDR54
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A75,994,378 - 75,998,385 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A75,994,394 - 75,998,385 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A74,488,345 - 74,492,392 (+)NCBIMhudiblu_PPA_v0panPan3
Wdr54
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629210,087,698 - 10,091,606 (-)NCBI
SpeTri2.0NW_004936556646,312 - 649,961 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR54
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl368,614,019 - 68,622,598 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1368,614,019 - 68,618,433 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2371,804,660 - 71,809,072 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WDR54
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11432,851,904 - 32,855,918 (-)NCBI
ChlSab1.1 Ensembl1432,851,959 - 32,855,912 (-)Ensembl
Wdr54
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474929,076,668 - 29,080,169 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 16 12 8 8
Low 5 5 6 6 6 6 6 6 2 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000013583   ⟹   ENSCAFP00000012568
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1748,700,431 - 48,704,344 (-)Ensembl
RefSeq Acc Id: XM_005630546   ⟹   XP_005630603
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11748,700,432 - 48,704,435 (-)NCBI
Dog10K_Boxer_Tasha1748,342,069 - 48,346,055 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005630547   ⟹   XP_005630604
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11748,700,432 - 48,734,250 (-)NCBI
Dog10K_Boxer_Tasha1748,342,069 - 48,375,651 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038499133   ⟹   XP_038355061
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11748,576,773 - 48,580,756 (-)NCBI
RefSeq Acc Id: XM_038499134   ⟹   XP_038355062
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11748,576,773 - 48,610,446 (-)NCBI
RefSeq Acc Id: XM_038561720   ⟹   XP_038417648
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01749,201,309 - 49,205,297 (-)NCBI
RefSeq Acc Id: XM_038561721   ⟹   XP_038417649
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01749,201,309 - 49,235,141 (-)NCBI
RefSeq Acc Id: XM_038625762   ⟹   XP_038481690
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01748,643,308 - 48,647,303 (-)NCBI
RefSeq Acc Id: XM_038625763   ⟹   XP_038481691
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01748,643,308 - 48,676,908 (-)NCBI
RefSeq Acc Id: XM_038691692   ⟹   XP_038547620
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01749,559,726 - 49,563,714 (-)NCBI
RefSeq Acc Id: XM_038691693   ⟹   XP_038547621
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01749,559,726 - 49,593,603 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_005630604   ⟸   XM_005630547
- UniProtKB: E2R2J3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005630603   ⟸   XM_005630546
- UniProtKB: E2R2J3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000012568   ⟸   ENSCAFT00000013583
RefSeq Acc Id: XP_038355062   ⟸   XM_038499134
RefSeq Acc Id: XP_038355061   ⟸   XM_038499133
RefSeq Acc Id: XP_038481691   ⟸   XM_038625763
RefSeq Acc Id: XP_038481690   ⟸   XM_038625762
RefSeq Acc Id: XP_038547621   ⟸   XM_038691693
RefSeq Acc Id: XP_038547620   ⟸   XM_038691692
RefSeq Acc Id: XP_038417649   ⟸   XM_038561721
RefSeq Acc Id: XP_038417648   ⟸   XM_038561720
Protein Domains
WD_REPEATS_REGION

Promoters
RGD ID:13686312
Promoter ID:EPDNEW_C4380
Type:multiple initiation site
Name:WDR54_1
Description:WD repeat domain 54
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11748,704,359 - 48,704,419EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000008561 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000012568 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000013583 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report cfa:475789 UniProtKB/TrEMBL
NCBI Gene WDR54 ENTREZGENE
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt E2R2J3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:48375 ENTREZGENE