Tacstd2 (tumor-associated calcium signal transducer 2) - Rat Genome Database

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Gene: Tacstd2 (tumor-associated calcium signal transducer 2) Rattus norvegicus
Analyze
Symbol: Tacstd2
Name: tumor-associated calcium signal transducer 2
RGD ID: 1359498
Description: Predicted to be involved in several processes, including negative regulation of branching involved in ureteric bud morphogenesis; negative regulation of cellular component organization; and negative regulation of substrate adhesion-dependent cell spreading. Predicted to be located in basal plasma membrane and lateral plasma membrane. Predicted to be active in extracellular space and nucleus. Human ortholog(s) of this gene implicated in corneal dystrophy and gelatinous drop-like corneal dystrophy. Orthologous to human TACSTD2 (tumor associated calcium signal transducer 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC72570; parturition-related protein 1; Prp1; Trop2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8498,037,620 - 98,039,320 (-)NCBIGRCr8
mRatBN7.2496,707,950 - 96,709,650 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl496,707,951 - 96,709,650 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4101,963,680 - 101,965,380 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0497,738,651 - 97,740,351 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0496,165,839 - 96,167,539 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0498,341,187 - 98,342,887 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl498,341,188 - 98,342,887 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04163,126,801 - 163,128,501 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4497,803,151 - 97,804,851 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1498,047,632 - 98,049,313 (-)NCBI
Celera491,374,254 - 91,375,954 (-)NCBICelera
Cytogenetic Map4q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
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Original Reference(s)
Tacstd2Ratcorneal dystrophy  ISOTACSTD2 (Homo sapiens)1599194gelatinous drop-like corneal dystrophyRGD 
Object Symbol
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Reference
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Original Reference(s)
Tacstd2Ratcorneal dystrophy  ISOTACSTD2 (Homo sapiens)8554872ClinVar Annotator: match by term: Corneal Dystrophy and Dominant/RecessiveClinVarPMID:25741868
Tacstd2Ratgelatinous drop-like corneal dystrophy  ISOTACSTD2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10192395 more ...
Object Symbol
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Original Reference(s)
Tacstd2Ratendometriosis  ISOTACSTD2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20864642
Tacstd2Ratgelatinous drop-like corneal dystrophy  ISOTACSTD2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
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Original Reference(s)
Tacstd2Ratgelatinous drop-like corneal dystrophy  ISOTACSTD2 (Homo sapiens)7240710 OMIM 

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Original Reference(s)
Tacstd2Rat(-)-epigallocatechin 3-gallate multiple interactionsISOTACSTD2 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TACSTD2 mRNACTDPMID:22079256
Tacstd2Rat1,1-dichloroethene decreases expressionISOTacstd2 (Mus musculus)6480464vinylidene chloride results in decreased expression of TACSTD2 mRNACTDPMID:26682919
Tacstd2Rat1-nitropyrene decreases expressionISOTACSTD2 (Homo sapiens)64804641-nitropyrene results in decreased expression of TACSTD2 mRNACTDPMID:19041380
Tacstd2Rat17alpha-ethynylestradiol increases expressionISOTacstd2 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of TACSTD2 mRNACTDPMID:17942748
Tacstd2Rat17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of TACSTD2 mRNACTDPMID:30387366
Tacstd2Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of TACSTD2 mRNACTDPMID:15576828 and PMID:17557909
Tacstd2Rat17beta-estradiol affects expressionISOTacstd2 (Mus musculus)6480464Estradiol affects the expression of TACSTD2 mRNACTDPMID:15598610
Tacstd2Rat17beta-estradiol increases expressionISOTACSTD2 (Homo sapiens)6480464Estradiol results in increased expression of TACSTD2 mRNACTDPMID:23019147 and PMID:24424067
Tacstd2Rat17beta-estradiol multiple interactionsISOTACSTD2 (Homo sapiens)6480464[Estradiol co-treated with Progesterone] results in decreased expression of TACSTD2 mRNA and [Estradiol co-treated with TGFB1 protein] results in decreased expression of TACSTD2 mRNACTDPMID:20660070 and PMID:30165855
Tacstd2Rat17beta-estradiol increases expressionISOTacstd2 (Mus musculus)6480464Estradiol results in increased expression of TACSTD2 mRNACTDPMID:15289156
Tacstd2Rat17beta-estradiol 3-benzoate decreases methylationEXP 6480464estradiol 3-benzoate results in decreased methylation of TACSTD2 promoterCTDPMID:27415467
Tacstd2Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOTacstd2 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Tacstd2Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOTacstd2 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Tacstd2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOTACSTD2 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of TACSTD2 mRNACTDPMID:12377990
Tacstd2Rat2,6-dimethoxyphenol multiple interactionsISOTACSTD2 (Homo sapiens)6480464[Sodium Chloride co-treated with pyrogallol 1 and 3-dimethyl ether] results in increased expression of and affects the localization of TACSTD2 proteinCTDPMID:38598786
Tacstd2Rat2-palmitoylglycerol increases expressionISOTACSTD2 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of TACSTD2 mRNACTDPMID:37199045
Tacstd2Rat3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expressionISOTacstd2 (Mus musculus)64804643 more ...CTDPMID:21826054
Tacstd2Rat4,4'-sulfonyldiphenol increases expressionISOTacstd2 (Mus musculus)6480464bisphenol S results in increased expression of TACSTD2 mRNACTDPMID:30951980
Tacstd2Rat4,4'-sulfonyldiphenol multiple interactionsISOTacstd2 (Mus musculus)6480464[bisphenol S co-treated with Tretinoin] results in decreased expression of TACSTD2 mRNACTDPMID:30951980
Tacstd2Rat4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid decreases expressionISOTACSTD2 (Homo sapiens)6480464Am 580 results in decreased expression of TACSTD2 mRNACTDPMID:16982809

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Biological Process
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Original Reference(s)
Tacstd2Ratbiological_process  ND 15984071/2007: no relevant rat dataRGD 
Tacstd2Ratnegative regulation of branching involved in ureteric bud morphogenesis involved_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
Tacstd2Ratnegative regulation of branching involved in ureteric bud morphogenesis involved_inISOTacstd2 (Mus musculus)1624291 PMID:22194864RGDPMID:22194864
Tacstd2Ratnegative regulation of branching involved in ureteric bud morphogenesis involved_inISSUniProtKB:Q8BGV31600115GO_REF:0000024UniProtGO_REF:0000024
Tacstd2Ratnegative regulation of cell motility involved_inISSUniProtKB:Q8BGV31600115GO_REF:0000024UniProtGO_REF:0000024
Tacstd2Ratnegative regulation of cell motility involved_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
Tacstd2Ratnegative regulation of cell motility involved_inISOTacstd2 (Mus musculus)1624291 PMID:22194864RGDPMID:22194864
Tacstd2Ratnegative regulation of epithelial cell migration involved_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
Tacstd2Ratnegative regulation of epithelial cell migration involved_inISOTacstd2 (Mus musculus)1624291 PMID:22194864RGDPMID:22194864
Tacstd2Ratnegative regulation of epithelial cell migration involved_inISSUniProtKB:Q8BGV31600115GO_REF:0000024UniProtGO_REF:0000024
Tacstd2Ratnegative regulation of ruffle assembly involved_inISSUniProtKB:Q8BGV31600115GO_REF:0000024UniProtGO_REF:0000024
Tacstd2Ratnegative regulation of ruffle assembly involved_inISOTacstd2 (Mus musculus)1624291 PMID:22194864RGDPMID:22194864
Tacstd2Ratnegative regulation of ruffle assembly involved_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
Tacstd2Ratnegative regulation of stress fiber assembly involved_inISSUniProtKB:Q8BGV31600115GO_REF:0000024UniProtGO_REF:0000024
Tacstd2Ratnegative regulation of stress fiber assembly involved_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
Tacstd2Ratnegative regulation of stress fiber assembly involved_inISOTacstd2 (Mus musculus)1624291 PMID:22194864RGDPMID:22194864
Tacstd2Ratnegative regulation of substrate adhesion-dependent cell spreading involved_inISOTacstd2 (Mus musculus)1624291 PMID:22194864RGDPMID:22194864
Tacstd2Ratnegative regulation of substrate adhesion-dependent cell spreading involved_inISSUniProtKB:Q8BGV31600115GO_REF:0000024UniProtGO_REF:0000024
Tacstd2Ratnegative regulation of substrate adhesion-dependent cell spreading involved_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
Tacstd2Ratpositive regulation of stem cell differentiation acts_upstream_of_or_withinISOTacstd2 (Mus musculus)1624291 PMID:23070813RGDPMID:23070813
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Cellular Component
1 to 19 of 19 rows

  
Object Symbol
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Reference
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Original Reference(s)
Tacstd2Ratbasal plasma membrane located_inISOTacstd2 (Mus musculus)1624291 PMID:22194864RGDPMID:22194864
Tacstd2Ratbasal plasma membrane located_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
Tacstd2Ratbasal plasma membrane located_inISSUniProtKB:Q8BGV31600115GO_REF:0000024UniProtGO_REF:0000024
Tacstd2Ratextracellular space located_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
Tacstd2Ratextracellular space located_inISOTacstd2 (Mus musculus)1624291 PMID:23070813RGDPMID:23070813
Tacstd2Ratextracellular space is_active_inIBAMGI:1861606 and PANTHER:PTN0003667191600115GO_REF:0000033GO_CentralGO_REF:0000033
Tacstd2Ratlateral plasma membrane located_inISOTacstd2 (Mus musculus)1624291 PMID:22194864RGDPMID:22194864
Tacstd2Ratlateral plasma membrane located_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
Tacstd2Ratlateral plasma membrane located_inISSUniProtKB:Q8BGV31600115GO_REF:0000024UniProtGO_REF:0000024
Tacstd2Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Tacstd2Ratmembrane located_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
Tacstd2Ratmembrane located_inISOTacstd2 (Mus musculus)1624291 PMID:23070813RGDPMID:23070813
Tacstd2Ratmembrane located_inIEAInterPro:IPR0434061600115GO_REF:0000002InterProGO_REF:0000002
Tacstd2Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Tacstd2Ratnucleus located_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
Tacstd2Ratnucleus located_inISOTacstd2 (Mus musculus)1624291 PMID:23070813RGDPMID:23070813
Tacstd2Ratnucleus is_active_inIBAMGI:1861606 and PANTHER:PTN0003667191600115GO_REF:0000033GO_CentralGO_REF:0000033
Tacstd2Ratplasma membrane located_inISOTacstd2 (Mus musculus)1624291 PMID:9462726RGDPMID:9462726
Tacstd2Ratplasma membrane located_inIEAUniProtKB:Q8BGV3 and ensembl:ENSMUSP000000600991600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function

  
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Original Reference(s)
Tacstd2Ratprotein binding enablesISOTACSTD2 (Homo sapiens)1624291UniProtKB:P27958-PRO_0000037576 more ...RGDPMID:15607035 and PMID:32296183


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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
9. Identification of the gene responsible for gelatinous drop-like corneal dystrophy. Tsujikawa M, etal., Nat Genet. 1999 Apr;21(4):420-3.
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PMID:9462726   PMID:19199708   PMID:21743029   PMID:22194864   PMID:23070813   PMID:23376485  



Tacstd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8498,037,620 - 98,039,320 (-)NCBIGRCr8
mRatBN7.2496,707,950 - 96,709,650 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl496,707,951 - 96,709,650 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4101,963,680 - 101,965,380 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0497,738,651 - 97,740,351 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0496,165,839 - 96,167,539 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0498,341,187 - 98,342,887 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl498,341,188 - 98,342,887 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04163,126,801 - 163,128,501 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4497,803,151 - 97,804,851 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1498,047,632 - 98,049,313 (-)NCBI
Celera491,374,254 - 91,375,954 (-)NCBICelera
Cytogenetic Map4q31NCBI
TACSTD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38158,575,433 - 58,577,252 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl158,575,433 - 58,577,252 (-)EnsemblGRCh38hg38GRCh38
GRCh37159,041,105 - 59,042,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36158,813,231 - 58,816,033 (-)NCBINCBI36Build 36hg18NCBI36
Build 34158,752,663 - 58,755,466NCBI
Celera157,324,947 - 57,327,018 (-)NCBICelera
Cytogenetic Map1p32.1NCBI
HuRef157,151,670 - 57,153,741 (-)NCBIHuRef
CHM1_1159,156,449 - 59,158,520 (-)NCBICHM1_1
T2T-CHM13v2.0158,453,397 - 58,455,216 (-)NCBIT2T-CHM13v2.0
Tacstd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39667,511,043 - 67,512,806 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl667,511,046 - 67,512,780 (-)EnsemblGRCm39 Ensembl
GRCm38667,534,059 - 67,535,822 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl667,534,062 - 67,535,796 (-)EnsemblGRCm38mm10GRCm38
MGSCv37667,484,053 - 67,485,816 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36667,463,640 - 67,465,374 (-)NCBIMGSCv36mm8
Celera669,652,700 - 69,654,464 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map630.88NCBI
Tacstd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554641,282,989 - 1,284,785 (+)NCBIChiLan1.0ChiLan1.0
TACSTD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21168,269,077 - 168,271,255 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11167,421,430 - 167,423,741 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0157,838,661 - 57,841,444 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1159,544,868 - 59,547,207 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl159,545,625 - 59,546,596 (-)Ensemblpanpan1.1panPan2
TACSTD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1551,122,469 - 51,123,753 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha551,187,934 - 51,189,787 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0551,303,042 - 51,304,084 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1551,252,727 - 51,254,573 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0551,198,006 - 51,199,866 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0551,481,572 - 51,483,437 (+)NCBIUU_Cfam_GSD_1.0
Tacstd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505872,207,616 - 72,209,632 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365223,206,957 - 3,207,919 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365223,206,826 - 3,208,675 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TACSTD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6153,859,482 - 153,861,492 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16153,859,488 - 153,861,508 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26141,453,653 - 141,455,459 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TACSTD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12074,403,547 - 74,406,756 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603342,956,630 - 42,959,787 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tacstd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248621,721,030 - 1,722,780 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Tacstd2
5 total Variants

Predicted Target Of
Summary Value
Count of predictions:113
Count of miRNA genes:90
Interacting mature miRNAs:95
Transcripts:ENSRNOT00000010156
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat

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AI575674  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2496,708,041 - 96,708,228 (+)MAPPERmRatBN7.2
Rnor_6.0498,341,279 - 98,341,465NCBIRnor6.0
Rnor_5.04163,126,893 - 163,127,079UniSTSRnor5.0
RGSC_v3.4497,803,243 - 97,803,429UniSTSRGSC3.4
Celera491,374,346 - 91,374,532UniSTS
RH 3.4 Map4607.7UniSTS
Cytogenetic Map4q31UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 9 11 84 68 78 47 20 47 6 147 38 73 45 49 31



Ensembl Acc Id: ENSRNOT00000010156   ⟹   ENSRNOP00000010156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl496,707,951 - 96,709,650 (-)Ensembl
Rnor_6.0 Ensembl498,341,188 - 98,342,887 (-)Ensembl
RefSeq Acc Id: NM_001009540   ⟹   NP_001009540
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8498,037,620 - 98,039,320 (-)NCBI
mRatBN7.2496,707,950 - 96,709,650 (-)NCBI
Rnor_6.0498,341,187 - 98,342,887 (-)NCBI
Rnor_5.04163,126,801 - 163,128,501 (-)NCBI
RGSC_v3.4497,803,151 - 97,804,851 (-)RGD
Celera491,374,254 - 91,375,954 (-)RGD
Sequence:
Protein RefSeqs NP_001009540 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH60519 (Get FASTA)   NCBI Sequence Viewer  
  AAO67351 (Get FASTA)   NCBI Sequence Viewer  
  EDL91571 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000106672
GenBank Protein Q6P9Z6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009540   ⟸   NM_001009540
- Peptide Label: precursor
- UniProtKB: Q6K0P4 (UniProtKB/Swiss-Prot),   Q6P9Z6 (UniProtKB/Swiss-Prot),   A0A0G2JSJ1 (UniProtKB/TrEMBL),   A6KF53 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010156   ⟸   ENSRNOT00000010156
Thyroglobulin type-1

Name Modeler Protein Id AA Range Protein Structure
AF-Q6P9Z6-F1-model_v2 AlphaFold Q6P9Z6 1-317 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693104
Promoter ID:EPDNEW_R3628
Type:single initiation site
Name:Tacstd2_1
Description:tumor-associated calcium signal transducer 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0498,342,887 - 98,342,947EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-44558 BioCyc
Ensembl Genes ENSRNOG00000007740 Ensembl
  ENSRNOG00000078917 ENTREZGENE
Ensembl Transcript ENSRNOT00000126716 ENTREZGENE
Gene3D-CATH 4.10.800.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5597863 IMAGE-MGC_LOAD
InterPro EPCAM-Trop-2_C UniProtKB/Swiss-Prot
  EPCAM/Trop-2 UniProtKB/Swiss-Prot
  EpCAM_N UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot
  Thyroglobulin_1_sf UniProtKB/Swiss-Prot
KEGG Report rno:494343 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72570 IMAGE-MGC_LOAD
NCBI Gene 494343 ENTREZGENE
PANTHER PTHR14168 UniProtKB/Swiss-Prot
  TUMOR-ASSOCIATED CALCIUM SIGNAL TRANSDUCER 2 UniProtKB/Swiss-Prot
Pfam EPCAM-Trop-2_C UniProtKB/Swiss-Prot
  EpCAM_N UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot
PhenoGen Tacstd2 PhenoGen
PROSITE THYROGLOBULIN_1_1 UniProtKB/Swiss-Prot
  THYROGLOBULIN_1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007740 RatGTEx
  ENSRNOG00000078917 RatGTEx
SMART SM00211 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57610 UniProtKB/Swiss-Prot
UniProt A0A0G2JSJ1 ENTREZGENE, UniProtKB/TrEMBL
  A6KF53 ENTREZGENE, UniProtKB/TrEMBL
  Q6K0P4 ENTREZGENE
  Q6P9Z6 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q6K0P4 UniProtKB/Swiss-Prot
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Tacstd2  tumor-associated calcium signal transducer 2      Symbol and Name status set to approved 1299863 APPROVED
2005-07-29 Tacstd2  tumor-associated calcium signal transducer 2      Symbol and Name status set to provisional 70820 PROVISIONAL