Ndufs7 (NADH:ubiquinone oxidoreductase core subunit S7) - Rat Genome Database

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Gene: Ndufs7 (NADH:ubiquinone oxidoreductase core subunit S7) Rattus norvegicus
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Symbol: Ndufs7
Name: NADH:ubiquinone oxidoreductase core subunit S7
RGD ID: 1310013
Description: Enables protease binding activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Located in neuronal cell body and synaptic membrane. Human ortholog(s) of this gene implicated in developmental disorder of mental health and nuclear type mitochondrial complex I deficiency 3. Orthologous to human NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7); PARTICIPATES IN doxorubicin pharmacokinetics pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362837; MGC105684; NADH dehydrogenase (ubiquinone) Fe-S protein 7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; NADH-ubiquinone oxidoreductase Fe-S protein 7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,103,226 - 10,110,862 (-)NCBIGRCr8
mRatBN7.279,452,556 - 9,460,135 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,450,392 - 9,460,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,335,345 - 12,342,615 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,210,685 - 14,217,955 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,072,020 - 12,079,284 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,318,776 - 12,326,403 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,318,757 - 12,326,392 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,488,476 - 12,496,073 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,963,916 - 10,971,188 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,963,916 - 10,971,188 (-)NCBI
Celera77,629,258 - 7,636,522 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufs7Ratbipolar disorder  ISONDUFS7 (Homo sapiens)6484696protein:decreased expression:prefrontal cortex (human)RGD 
Ndufs7RatCOVID-19  ISONDUFS7 (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Ndufs7Ratdevelopmental disorder of mental health  ISONDUFS7 (Homo sapiens)401854249DNA:SNP:CDS:multiple (human)RGD 
1 to 9 of 9 rows
Object Symbol
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Qualifier
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Reference
Notes
Source
Original Reference(s)
Ndufs7Ratcerebral creatine deficiency syndrome  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Cerebral creatine deficiency syndromeClinVarPMID:11978605 more ...
Ndufs7Ratcyclic hematopoiesis  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Cyclical neutropeniaClinVarPMID:28492532
Ndufs7Ratgenetic disease  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:11978605 more ...
Ndufs7Ratguanidinoacetate methyltransferase deficiency  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: GAMT DEFICIENCYClinVarPMID:11978605 more ...
Ndufs7RatLeigh disease  ISONDUFS7 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10330338 more ...
Ndufs7Ratmitochondrial complex I deficiency  ISONDUFS7 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11978605 more ...
Ndufs7Ratnuclear type mitochondrial complex I deficiency 1  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Mitochondrial complex I deficiency and nuclear type 1ClinVarPMID:25741868 and PMID:28492532
Ndufs7Ratnuclear type mitochondrial complex I deficiency 3  ISONDUFS7 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10330338 more ...
Ndufs7RatSubacute Necrotizing Encephalopathy of Leigh, Infantile  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Leigh's necrotizing encephalopathyClinVarPMID:10330338 more ...
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Object Symbol
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Evidence
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Reference
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Source
Original Reference(s)
Ndufs7Ratnuclear type mitochondrial complex I deficiency 3  ISONDUFS7 (Homo sapiens)7240710 OMIM 

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Object Symbol
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Original Reference(s)
Ndufs7Rat(+)-dexrazoxane increases expressionISONdufs7 (Mus musculus)6480464Dexrazoxane results in increased expression of NDUFS7 mRNACTDPMID:26873546
Ndufs7Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NDUFS7 mRNA]CTDPMID:31150632
Ndufs7Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of NDUFS7 mRNACTDPMID:32145629
Ndufs7Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of NDUFS7 mRNACTDPMID:15644576 and PMID:33387578
Ndufs7Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONdufs7 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NDUFS7 mRNACTDPMID:21570461 and PMID:24680724
Ndufs7Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of NDUFS7 mRNACTDPMID:21215274 and PMID:32109520
Ndufs7Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISONdufs7 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of NDUFS7 mRNACTDPMID:19465110
Ndufs7Rat4,4'-sulfonyldiphenol increases expressionISONdufs7 (Mus musculus)6480464bisphenol S results in increased expression of NDUFS7 mRNACTDPMID:39298647
Ndufs7Rat4,4'-sulfonyldiphenol increases methylationISONdufs7 (Mus musculus)6480464bisphenol S results in increased methylation of NDUFS7 exonCTDPMID:33297965
Ndufs7Rataflatoxin B1 decreases methylationISONDUFS7 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of NDUFS7 intronCTDPMID:30157460
Ndufs7Rataristolochic acid A increases expressionISONDUFS7 (Homo sapiens)6480464aristolochic acid I results in increased expression of NDUFS7 mRNACTDPMID:33212167
Ndufs7Ratarsenite(3-) decreases expressionISONdufs7 (Mus musculus)6480464arsenite results in decreased expression of NDUFS7 mRNACTDPMID:33053406
Ndufs7Ratarsenite(3-) multiple interactionsISONDUFS7 (Homo sapiens)6480464arsenite promotes the reaction [G3BP1 protein binds to NDUFS7 mRNA]CTDPMID:32406909
Ndufs7Ratastemizole increases expressionEXP 6480464Astemizole results in increased expression of NDUFS7 mRNACTDPMID:20221588
Ndufs7Ratbenzo[a]pyrene increases expressionISONdufs7 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of NDUFS7 mRNACTDPMID:22228805
Ndufs7Ratbenzo[a]pyrene decreases expressionISONdufs7 (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of NDUFS7 mRNACTDPMID:27195522
Ndufs7Ratbis(2-ethylhexyl) phthalate decreases expressionISONdufs7 (Mus musculus)6480464Diethylhexyl Phthalate results in decreased expression of NDUFS7 mRNACTDPMID:35550907
Ndufs7Ratbis(2-ethylhexyl) phthalate increases expressionISONdufs7 (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of NDUFS7 mRNACTDPMID:33754040
Ndufs7Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of NDUFS7 mRNACTDPMID:25181051
Ndufs7Ratbisphenol A increases expressionISONDUFS7 (Homo sapiens)6480464bisphenol A results in increased expression of NDUFS7 proteinCTDPMID:34186270

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Biological Process

  
Object Symbol
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Reference
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Source
Original Reference(s)
Ndufs7Rataerobic respiration involved_inIBAPANTHER:PTN000242188 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ndufs7Ratbiological_process  ND 159840712/06: no relevant rat dataRGD 
Ndufs7Ratelectron transport coupled proton transport involved_inIBAPANTHER:PTN000242188 and UniProtKB:P0AFC71600115GO_REF:0000033GO_CentralGO_REF:0000033
Ndufs7Ratmitochondrial electron transport, NADH to ubiquinone involved_inISONDUFS7 (Homo sapiens)1624291 PMID:17275378RGDPMID:17275378
Ndufs7Ratmitochondrial electron transport, NADH to ubiquinone involved_inIEAUniProtKB:O75251 and ensembl:ENSP000002336271600115GO_REF:0000107EnsemblGO_REF:0000107
Ndufs7Ratmitochondrial respiratory chain complex I assembly involved_inISONDUFS7 (Homo sapiens)1624291 PMID:11112787RGDPMID:11112787
Ndufs7Ratmitochondrial respiratory chain complex I assembly involved_inIBAFB:FBgn0030718 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ndufs7Ratmitochondrial respiratory chain complex I assembly involved_inIEAUniProtKB:O75251 and ensembl:ENSP000002336271600115GO_REF:0000107EnsemblGO_REF:0000107

Cellular Component
1 to 11 of 11 rows

  
1 to 11 of 11 rows

Molecular Function
1 to 17 of 17 rows

  
Object Symbol
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Term
Qualifier
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Reference
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Original Reference(s)
Ndufs7Rat4 iron, 4 sulfur cluster binding enablesIEAUniProtKB-KW:KW-00041600115GO_REF:0000043UniProtGO_REF:0000043
Ndufs7Rat4 iron, 4 sulfur cluster binding enablesIEAInterPro:IPR0061381600115GO_REF:0000002InterProGO_REF:0000002
Ndufs7Ratiron-sulfur cluster binding enablesIEAInterPro:IPR0061371600115GO_REF:0000002InterProGO_REF:0000002
Ndufs7Ratiron-sulfur cluster binding enablesIEAUniProtKB-KW:KW-04111600115GO_REF:0000043UniProtGO_REF:0000043
Ndufs7Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Ndufs7Ratmonooxygenase activity enablesIEAUniProtKB:O75251 and ensembl:ENSP000002336271600115GO_REF:0000107EnsemblGO_REF:0000107
Ndufs7Ratmonooxygenase activity enablesISONDUFS7 (Homo sapiens)1624291 PMID:27226634RGDPMID:27226634
Ndufs7RatNADH dehydrogenase (ubiquinone) activity enablesISONDUFS7 (Homo sapiens)1624291 PMID:17275378RGDPMID:17275378
Ndufs7RatNADH dehydrogenase (ubiquinone) activity enablesIBAPANTHER:PTN000242188 and UniProtKB:O752511600115GO_REF:0000033GO_CentralGO_REF:0000033
Ndufs7RatNADH dehydrogenase (ubiquinone) activity enablesIEAInterPro:IPR0061381600115GO_REF:0000002InterProGO_REF:0000002
Ndufs7RatNADH dehydrogenase (ubiquinone) activity enablesIEAUniProtKB:O75251 and ensembl:ENSP000002336271600115GO_REF:0000107EnsemblGO_REF:0000107
Ndufs7RatNADH dehydrogenase activity contributes_toISONDUFS7 (Homo sapiens)1624291 PMID:14749350RGDPMID:14749350
Ndufs7RatNADH dehydrogenase activity contributes_toIEAUniProtKB:O75251 and ensembl:ENSP000002336271600115GO_REF:0000107EnsemblGO_REF:0000107
Ndufs7Ratprotease binding  IPIPsen1 (Rattus norvegicus)6484662 RGD 
Ndufs7Ratprotease binding  IPINcstn (Rattus norvegicus)6484662 RGD 
Ndufs7Ratprotein binding enablesISONDUFS7 (Homo sapiens)1624291UniProtKB:P28331 more ...RGDPMID:15186778 more ...
Ndufs7Ratquinone binding enablesIEAInterPro:IPR0061381600115GO_REF:0000002InterProGO_REF:0000002
1 to 17 of 17 rows

Imported Annotations - SMPDB

Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Ndufs7Ratdoxorubicin pharmacokinetics pathway   ISONDUFS7 (Homo sapiens)10402751 SMPDBSMP:00650

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufs7RatAlzheimer's disease pathway   IEA 6907045 KEGGrno:05010
Ndufs7RatHuntington's disease pathway   IEA 6907045 KEGGrno:05016
Ndufs7Ratoxidative phosphorylation pathway  IEA 6907045 KEGGrno:00190
Ndufs7RatParkinson's disease pathway   IEA 6907045 KEGGrno:05012

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#
Reference Title
Reference Citation
1. Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder. Andreazza AC, etal., Arch Gen Psychiatry. 2010 Apr;67(4):360-8.
2. Identification of two novel synaptic ¿-secretase associated proteins that affect amyloid ß-peptide levels without altering Notch processing. Frykman S, etal., Neurochem Int. 2012 Jul;61(1):108-18. doi: 10.1016/j.neuint.2012.03.016. Epub 2012 Apr 10.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Proteomic and Metabolomic Analyses of Mitochondrial Complex I-deficient Mouse Model Generated by Spontaneous B2 Short Interspersed Nuclear Element (SINE) Insertion into NADH Dehydrogenase (Ubiquinone) Fe-S Protein 4 (Ndufs4) Gene. Leong DW, etal., J Biol Chem. 2012 Jun 8;287(24):20652-63. Epub 2012 Apr 25.
6. Mutation burden analysis of six common mental disorders in African Americans by whole genome sequencing. Liu Y, etal., Hum Mol Genet. 2022 Nov 10;31(22):3769-3776. doi: 10.1093/hmg/ddac129.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
1 to 15 of 15 rows
PMID:11112787   PMID:12477932   PMID:12611891   PMID:12865426   PMID:14651853   PMID:14749350   PMID:18614015   PMID:28844695   PMID:34800366  



Ndufs7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,103,226 - 10,110,862 (-)NCBIGRCr8
mRatBN7.279,452,556 - 9,460,135 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,450,392 - 9,460,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,335,345 - 12,342,615 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,210,685 - 14,217,955 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,072,020 - 12,079,284 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,318,776 - 12,326,403 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,318,757 - 12,326,392 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,488,476 - 12,496,073 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,963,916 - 10,971,188 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,963,916 - 10,971,188 (-)NCBI
Celera77,629,258 - 7,636,522 (-)NCBICelera
Cytogenetic Map7q11NCBI
NDUFS7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,383,907 - 1,395,584 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,383,527 - 1,395,589 (+)EnsemblGRCh38hg38GRCh38
GRCh37191,383,906 - 1,395,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,334,906 - 1,346,581 (+)NCBINCBI36Build 36hg18NCBI36
Build 34191,334,905 - 1,346,582NCBI
Celera191,318,163 - 1,329,866 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef191,158,739 - 1,170,441 (+)NCBIHuRef
CHM1_1191,383,997 - 1,395,689 (+)NCBICHM1_1
T2T-CHM13v2.0191,353,497 - 1,365,582 (+)NCBIT2T-CHM13v2.0
Ndufs7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,084,939 - 80,092,628 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,084,955 - 80,092,628 (+)EnsemblGRCm39 Ensembl
GRCm381080,249,105 - 80,256,794 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,249,121 - 80,256,794 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,712,197 - 79,719,537 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,652,581 - 79,659,921 (+)NCBIMGSCv36mm8
Celera1081,264,325 - 81,271,665 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Ndufs7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,540,450 - 6,547,975 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,540,360 - 6,548,072 (-)NCBIChiLan1.0ChiLan1.0
NDUFS7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,729,271 - 5,741,584 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,965,943 - 4,978,502 (+)NCBINHGRI_mPanPan1
PanPan1.1191,357,389 - 1,369,539 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl191,357,389 - 1,369,539 (+)Ensemblpanpan1.1panPan2
NDUFS7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,443,264 - 57,448,892 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,443,258 - 57,448,825 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,234,471 - 57,239,883 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,173,790 - 58,179,361 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,173,789 - 58,179,144 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,229,766 - 57,236,137 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,709,442 - 57,714,993 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,911,449 - 57,916,852 (-)NCBIUU_Cfam_GSD_1.0
Ndufs7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,114,748 - 217,119,743 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588715,162 - 719,968 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936588715,093 - 720,035 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFS7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1277,080,311 - 77,087,141 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,971,901 - 77,979,426 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFS7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.161,152,380 - 1,163,488 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl61,152,540 - 1,164,175 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660817,698,881 - 7,710,027 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ndufs7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,294,327 - 7,306,814 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,298,290 - 7,307,113 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ndufs7
20 total Variants

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:55
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000039728
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 13 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat

1 to 10 of 13 rows
RH128241  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8710,103,235 - 10,104,067 (+)Marker Load Pipeline
mRatBN7.279,452,565 - 9,453,397 (+)MAPPERmRatBN7.2
Rnor_6.0712,318,786 - 12,319,617NCBIRnor6.0
Rnor_5.0712,488,486 - 12,489,317UniSTSRnor5.0
RGSC_v3.4710,963,926 - 10,964,757UniSTSRGSC3.4
Celera77,629,268 - 7,630,099UniSTS
Cytogenetic Map7q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000039728   ⟹   ENSRNOP00000037256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,452,555 - 9,460,195 (-)Ensembl
Rnor_6.0 Ensembl712,318,757 - 12,326,392 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099635   ⟹   ENSRNOP00000095566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,450,392 - 9,459,835 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108576   ⟹   ENSRNOP00000092039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,450,392 - 9,460,158 (-)Ensembl
RefSeq Acc Id: NM_001008525   ⟹   NP_001008525
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,103,226 - 10,110,498 (-)NCBI
mRatBN7.279,452,556 - 9,459,828 (-)NCBI
Rnor_6.0712,318,776 - 12,326,048 (-)NCBI
Rnor_5.0712,488,476 - 12,496,073 (-)NCBI
RGSC_v3.4710,963,916 - 10,971,188 (-)RGD
Celera77,629,258 - 7,636,522 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240972   ⟹   XP_006241034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,103,226 - 10,110,862 (-)NCBI
mRatBN7.279,452,556 - 9,460,135 (-)NCBI
Rnor_6.0712,318,776 - 12,326,403 (-)NCBI
Rnor_5.0712,488,476 - 12,496,073 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079404   ⟹   XP_038935332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,103,226 - 10,110,805 (-)NCBI
mRatBN7.279,452,556 - 9,460,135 (-)NCBI
RefSeq Acc Id: XM_039079405   ⟹   XP_038935333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,103,226 - 10,107,996 (-)NCBI
mRatBN7.279,452,556 - 9,457,327 (-)NCBI
RefSeq Acc Id: NP_001008525   ⟸   NM_001008525
- UniProtKB: Q5RJN0 (UniProtKB/TrEMBL),   A6K8N6 (UniProtKB/TrEMBL),   A0A8I6AES7 (UniProtKB/TrEMBL),   A0A8I6B2Z5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241034   ⟸   XM_006240972
- Peptide Label: isoform X2
- UniProtKB: Q5RJN0 (UniProtKB/TrEMBL),   A6K8N6 (UniProtKB/TrEMBL),   A0A8I6AES7 (UniProtKB/TrEMBL),   A0A8I6B2Z5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000037256   ⟸   ENSRNOT00000039728
RefSeq Acc Id: XP_038935332   ⟸   XM_039079404
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AES7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935333   ⟸   XM_039079405
- Peptide Label: isoform X3
- UniProtKB: A6K8N7 (UniProtKB/TrEMBL)
Name Modeler Protein Id AA Range Protein Structure
AF-Q5RJN0-F1-model_v2 AlphaFold Q5RJN0 1-218 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13695028
Promoter ID:EPDNEW_R5553
Type:multiple initiation site
Name:Ndufs7_1
Description:NADH:ubiquinone oxidoreductase core subunit S7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0712,326,061 - 12,326,121EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-34926 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
Ensembl Genes ENSRNOG00000024568 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039728.6 UniProtKB/TrEMBL
  ENSRNOT00000099635.1 UniProtKB/TrEMBL
  ENSRNOT00000108576.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.12280 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7306868 IMAGE-MGC_LOAD
InterPro NADH_UbQ_OxRdtase-like_20kDa UniProtKB/TrEMBL
  NADH_UbQ_OxRdtase_20kDa_su UniProtKB/TrEMBL
KEGG Report rno:362837 UniProtKB/TrEMBL
MGC_CLONE MGC:105684 IMAGE-MGC_LOAD
NCBI Gene 362837 ENTREZGENE
PANTHER NADH DEHYDROGENASE UniProtKB/TrEMBL
  NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Oxidored_q6 UniProtKB/TrEMBL
PhenoGen Ndufs7 PhenoGen
PROSITE COMPLEX1_20K UniProtKB/TrEMBL
RatGTEx ENSRNOG00000024568 RatGTEx
Superfamily-SCOP HydA/Nqo6-like UniProtKB/TrEMBL
UniProt A0A8I6AES7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6B2Z5 ENTREZGENE, UniProtKB/TrEMBL
  A6K8N5_RAT UniProtKB/TrEMBL
  A6K8N6 ENTREZGENE, UniProtKB/TrEMBL
  A6K8N7 ENTREZGENE, UniProtKB/TrEMBL
  A6K8N8_RAT UniProtKB/TrEMBL
  A6K8N9_RAT UniProtKB/TrEMBL
  F7ELE5_RAT UniProtKB/TrEMBL
  Q5RJN0 ENTREZGENE
UniProt Secondary Q5RJN0 UniProtKB/TrEMBL
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-29 Ndufs7  NADH:ubiquinone oxidoreductase core subunit S7  Ndufs7  NADH dehydrogenase (ubiquinone) Fe-S protein 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ndufs7  NADH dehydrogenase (ubiquinone) Fe-S protein 7  Ndufs7_predicted  NADH dehydrogenase (ubiquinone) Fe-S protein 7 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ndufs7_predicted  NADH dehydrogenase (ubiquinone) Fe-S protein 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED