Ndufs7 (NADH:ubiquinone oxidoreductase core subunit S7) - Rat Genome Database

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Gene: Ndufs7 (NADH:ubiquinone oxidoreductase core subunit S7) Chinchilla lanigera
Analyze
Symbol: Ndufs7
Name: NADH:ubiquinone oxidoreductase core subunit S7
RGD ID: 8817241
Description: ENCODES a protein that exhibits monooxygenase activity (ortholog); NADH dehydrogenase (ubiquinone) activity (ortholog); NADH dehydrogenase activity (ortholog); INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (ortholog); mitochondrial respiratory chain complex I assembly (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; ASSOCIATED WITH bipolar disorder (ortholog); cerebral creatine deficiency syndrome (ortholog); COVID-19 (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,540,450 - 6,547,975 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,540,360 - 6,548,072 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufs7Chinchillabipolar disorder  ISONDUFS7 (Homo sapiens)9068941protein:decreased expression:prefrontal cortex (human)RGDPMID:20368511 and REF_RGD_ID:6484696
Ndufs7ChinchillaCOVID-19  ISONDUFS7 (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Ndufs7Chinchilladevelopmental disorder of mental health  ISONDUFS7 (Homo sapiens)9068941DNA:SNP:CDS:multiple (human)RGDPMID:35642741 and REF_RGD_ID:401854249
1 to 9 of 9 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufs7Chinchillacerebral creatine deficiency syndrome  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Cerebral creatine deficiency syndromeClinVarPMID:11978605 more ...
Ndufs7Chinchillacyclic hematopoiesis  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Cyclical neutropeniaClinVarPMID:28492532
Ndufs7Chinchillagenetic disease  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:11978605 more ...
Ndufs7Chinchillaguanidinoacetate methyltransferase deficiency  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: GAMT DEFICIENCYClinVarPMID:11978605 more ...
Ndufs7ChinchillaLeigh disease  ISONDUFS7 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10330338 more ...
Ndufs7Chinchillamitochondrial complex I deficiency  ISONDUFS7 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:11978605 more ...
Ndufs7Chinchillanuclear type mitochondrial complex I deficiency 1  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Mitochondrial complex I deficiency and nuclear type 1ClinVarPMID:25741868 and PMID:28492532
Ndufs7Chinchillanuclear type mitochondrial complex I deficiency 3  ISONDUFS7 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10330338 more ...
Ndufs7ChinchillaSubacute Necrotizing Encephalopathy of Leigh, Infantile  ISONDUFS7 (Homo sapiens)8554872ClinVar Annotator: match by term: Leigh's necrotizing encephalopathyClinVarPMID:10330338 more ...
1 to 9 of 9 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufs7Chinchillanuclear type mitochondrial complex I deficiency 3  ISONDUFS7 (Homo sapiens)7240710 OMIM 


Biological Process

  

Molecular Function

  

Imported Annotations - SMPDB

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ndufs7Chinchilladoxorubicin pharmacokinetics pathway   ISONDUFS7 (Homo sapiens)9068941 SMPDBSMP:00650

#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
PMID:22301074   PMID:30032202  



Ndufs7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,540,450 - 6,547,975 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,540,360 - 6,548,072 (-)NCBIChiLan1.0ChiLan1.0
NDUFS7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,383,907 - 1,395,584 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,383,527 - 1,395,589 (+)EnsemblGRCh38hg38GRCh38
GRCh37191,383,906 - 1,395,583 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,334,906 - 1,346,581 (+)NCBINCBI36Build 36hg18NCBI36
Build 34191,334,905 - 1,346,582NCBI
Celera191,318,163 - 1,329,866 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef191,158,739 - 1,170,441 (+)NCBIHuRef
CHM1_1191,383,997 - 1,395,689 (+)NCBICHM1_1
T2T-CHM13v2.0191,353,497 - 1,365,582 (+)NCBIT2T-CHM13v2.0
Ndufs7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,084,939 - 80,092,628 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,084,955 - 80,092,628 (+)EnsemblGRCm39 Ensembl
GRCm381080,249,105 - 80,256,794 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,249,121 - 80,256,794 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,712,197 - 79,719,537 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,652,581 - 79,659,921 (+)NCBIMGSCv36mm8
Celera1081,264,325 - 81,271,665 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Ndufs7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,103,226 - 10,110,862 (-)NCBIGRCr8
mRatBN7.279,452,556 - 9,460,135 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,450,392 - 9,460,195 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,335,345 - 12,342,615 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,210,685 - 14,217,955 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,072,020 - 12,079,284 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,318,776 - 12,326,403 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,318,757 - 12,326,392 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,488,476 - 12,496,073 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,963,916 - 10,971,188 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,963,916 - 10,971,188 (-)NCBI
Celera77,629,258 - 7,636,522 (-)NCBICelera
Cytogenetic Map7q11NCBI
NDUFS7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,729,271 - 5,741,584 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,965,943 - 4,978,502 (+)NCBINHGRI_mPanPan1
PanPan1.1191,357,389 - 1,369,539 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl191,357,389 - 1,369,539 (+)Ensemblpanpan1.1panPan2
NDUFS7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,443,264 - 57,448,892 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,443,258 - 57,448,825 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,234,471 - 57,239,883 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,173,790 - 58,179,361 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,173,789 - 58,179,144 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,229,766 - 57,236,137 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,709,442 - 57,714,993 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,911,449 - 57,916,852 (-)NCBIUU_Cfam_GSD_1.0
Ndufs7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,114,748 - 217,119,743 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588715,162 - 719,968 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936588715,093 - 720,035 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDUFS7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1277,080,311 - 77,087,141 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,971,901 - 77,979,426 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NDUFS7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.161,152,380 - 1,163,488 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl61,152,540 - 1,164,175 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660817,698,881 - 7,710,027 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ndufs7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,294,327 - 7,306,814 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,298,290 - 7,307,113 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.
RefSeq Transcripts XM_005405978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01062085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBCB01003829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCLAT00000009888   ⟹   ENSCLAP00000009759
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554956,540,450 - 6,547,975 (-)Ensembl
RefSeq Acc Id: XM_005405978   ⟹   XP_005406035
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554956,540,360 - 6,548,072 (-)NCBI
Sequence:
Protein RefSeqs XP_005406035 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000009759
  ENSCLAP00000009759.1
RefSeq Acc Id: XP_005406035   ⟸   XM_005405978
- UniProtKB: A0A8C2VA76 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000009759   ⟸   ENSCLAT00000009888
NADH:ubiquinone oxidoreductase-like 20kDa subunit



1 to 13 of 13 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000006766 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000009888 ENTREZGENE
  ENSCLAT00000009888.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.12280 UniProtKB/TrEMBL
InterPro NADH_UbQ_OxRdtase-like_20kDa UniProtKB/TrEMBL
  NADH_UQ_OxRdtase_20Kd_su UniProtKB/TrEMBL
NCBI Gene Ndufs7 ENTREZGENE
PANTHER NADH DEHYDROGENASE UniProtKB/TrEMBL
  NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Oxidored_q6 UniProtKB/TrEMBL
PROSITE COMPLEX1_20K UniProtKB/TrEMBL
Superfamily-SCOP HydA/Nqo6-like UniProtKB/TrEMBL
UniProt A0A8C2VA76 ENTREZGENE, UniProtKB/TrEMBL
1 to 13 of 13 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Ndufs7  NADH:ubiquinone oxidoreductase core subunit S7    NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)  Symbol and/or name change 5135510 APPROVED