Ppp1r3c (protein phosphatase 1, regulatory subunit 3C) - Rat Genome Database

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Gene: Ppp1r3c (protein phosphatase 1, regulatory subunit 3C) Rattus norvegicus
Analyze
Symbol: Ppp1r3c
Name: protein phosphatase 1, regulatory subunit 3C
RGD ID: 1309132
Description: Enables [phosphorylase] phosphatase activity and enzyme binding activity. Contributes to phosphoprotein phosphatase activity. Involved in regulation of glycogen biosynthetic process and regulation of glycogen catabolic process. Located in glycogen granule. Orthologous to human PPP1R3C (protein phosphatase 1 regulatory subunit 3C); PARTICIPATES IN glycogen biosynthetic pathway; glycogen degradation pathway; insulin signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100910671; LOC309513; PP1 subunit R5; protein phosphatase 1 regulatory subunit 3C; protein phosphatase 1 regulatory subunit 3C-like; protein phosphatase 1 regulatory subunit 5; protein phosphatase 1, regulatory (inhibitor) subunit 3C; protein targeting to glycogen; PTG; R5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81243,873,524 - 243,878,527 (-)NCBIGRCr8
mRatBN7.21234,460,958 - 234,465,961 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1234,460,652 - 234,465,961 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,855,971 - 242,860,979 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01249,778,292 - 249,783,285 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,616,484 - 242,621,477 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01255,371,830 - 255,376,833 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1255,371,810 - 255,376,833 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01262,628,937 - 262,633,940 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41240,991,884 - 240,996,887 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11241,175,278 - 241,180,280 (-)NCBI
Celera1231,556,257 - 231,561,260 (-)NCBICelera
Cytogenetic Map1q53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ppp1r3cRatprostate cancer  ISOPPP1R3C (Homo sapiens)8554872ClinVar Annotator: match by term: Malignant tumor of prostateClinVarPMID:23265383
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Original Reference(s)
Ppp1r3cRatExperimental Liver Cirrhosis  ISOPPP1R3C (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25380136
Object Symbol
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Original Reference(s)
Ppp1r3cRattype 2 diabetes mellitus  ISSPpp1r3c (Mus musculus)13592920OMIM:125853 more ...MouseDO 

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Object Symbol
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Reference
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Original Reference(s)
Ppp1r3cRat(+)-catechin multiple interactionsISOPPP1R3C (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of PPP1R3C mRNACTDPMID:24763279
Ppp1r3cRat(1->4)-beta-D-glucan multiple interactionsISOPpp1r3c (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PPP1R3C mRNACTDPMID:36331819
Ppp1r3cRat(S)-amphetamine increases expressionISOPpp1r3c (Mus musculus)6480464Dextroamphetamine results in increased expression of PPP1R3C mRNACTDPMID:19194377
Ppp1r3cRat1,2-dichloroethane decreases expressionISOPpp1r3c (Mus musculus)6480464ethylene dichloride results in decreased expression of PPP1R3C mRNACTDPMID:28960355
Ppp1r3cRat1-naphthyl isothiocyanate decreases expressionEXP 64804641-Naphthylisothiocyanate results in decreased expression of PPP1R3C mRNACTDPMID:25380136 and PMID:30723492
Ppp1r3cRat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of PPP1R3C mRNACTDPMID:17351261
Ppp1r3cRat17beta-estradiol multiple interactionsISOPPP1R3C (Homo sapiens)6480464[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of PPP1R3C mRNA and [Estradiol co-treated with TGFB1 protein] results in increased expression of PPP1R3C mRNACTDPMID:19619570 and PMID:30165855
Ppp1r3cRat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of PPP1R3C mRNACTDPMID:35192832
Ppp1r3cRat17beta-estradiol increases expressionISOPpp1r3c (Mus musculus)6480464Estradiol results in increased expression of PPP1R3C mRNACTDPMID:39298647
Ppp1r3cRat17beta-estradiol affects expressionEXP 6480464Estradiol affects the expression of PPP1R3C mRNACTDPMID:32145629
Ppp1r3cRat17beta-estradiol decreases expressionISOPPP1R3C (Homo sapiens)6480464Estradiol results in decreased expression of PPP1R3C mRNACTDPMID:19619570 more ...
Ppp1r3cRat2,2',5,5'-tetrachlorobiphenyl increases expressionEXP 64804642 more ...CTDPMID:23829299
Ppp1r3cRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPPP1R3C (Homo sapiens)6480464[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of PPP1R3C mRNACTDPMID:19619570
Ppp1r3cRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PPP1R3C mRNACTDPMID:33387578
Ppp1r3cRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPpp1r3c (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of PPP1R3C mRNACTDPMID:26290441
Ppp1r3cRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPpp1r3c (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PPP1R3C mRNACTDPMID:19770486 more ...
Ppp1r3cRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPpp1r3c (Mus musculus)6480464[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of PPP1R3C mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PPP1R3C gene]CTDPMID:25975270 and PMID:28213091
Ppp1r3cRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PPP1R3C mRNACTDPMID:21215274
Ppp1r3cRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPPP1R3C (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of PPP1R3C mRNACTDPMID:19619570 and PMID:20106945
Ppp1r3cRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPpp1r3c (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of PPP1R3C mRNACTDPMID:19933214 more ...

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Biological Process
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Original Reference(s)
Ppp1r3cRatglycogen biosynthetic process involved_inIEAUniRule:UR0000285561600115GO_REF:0000104UniProtGO_REF:0000104
Ppp1r3cRatglycogen biosynthetic process acts_upstream_of_or_withinISOPpp1r3c (Mus musculus)1624291 PMID:10683377RGDPMID:10683377
Ppp1r3cRatglycogen biosynthetic process involved_inISOPpp1r3c (Mus musculus)1624291 PMID:9045612RGDPMID:9045612
Ppp1r3cRatglycogen biosynthetic process involved_inIEAUniProtKB:Q7TMB3 and ensembl:ENSMUSP000000845781600115GO_REF:0000107EnsemblGO_REF:0000107
Ppp1r3cRatglycogen biosynthetic process involved_inISSUniProtKB:Q7TMB31600115GO_REF:0000024UniProtGO_REF:0000024
Ppp1r3cRatglycogen metabolic process involved_inISSUniProtKB:Q7TMB31600115GO_REF:0000024UniProtGO_REF:0000024
Ppp1r3cRatglycogen metabolic process acts_upstream_of_or_withinIEAUniProtKB:Q7TMB3 and ensembl:ENSMUSP000000845781600115GO_REF:0000107EnsemblGO_REF:0000107
Ppp1r3cRatglycogen metabolic process acts_upstream_of_or_withinISOPpp1r3c (Mus musculus)1624291MGI:1341085 PMID:21552327 and PMID:9045612RGDPMID:21552327 and PMID:9045612
Ppp1r3cRatglycogen metabolic process involved_inIEAUniRule:UR0000285561600115GO_REF:0000104UniProtGO_REF:0000104
Ppp1r3cRatglycogen metabolic process involved_inIEAUniProtKB-KW:KW-03211600115GO_REF:0000043UniProtGO_REF:0000043
Ppp1r3cRatregulation of glycogen biosynthetic process  IDA 2306167 RGD 
Ppp1r3cRatregulation of glycogen biosynthetic process involved_inIBAMGI:1923737 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ppp1r3cRatregulation of glycogen catabolic process  IDA 2306167 RGD 
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Cellular Component

  
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Original Reference(s)
Ppp1r3cRatcytosol is_active_inIEAUniProtKB:Q7TMB3 and ensembl:ENSMUSP000000845781600115GO_REF:0000107EnsemblGO_REF:0000107
Ppp1r3cRatcytosol is_active_inISOPpp1r3c (Mus musculus)1624291 PMID:9045612RGDPMID:9045612
Ppp1r3cRatglycogen granule  IDA 2306167 RGD 
Ppp1r3cRatprotein phosphatase type 1 complex part_ofIBAFB:FBgn0036428 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 15 of 15 rows

  
Object Symbol
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Original Reference(s)
Ppp1r3cRat[phosphorylase] phosphatase activity enablesIMP 2306166PMID:15752363UniProt 
Ppp1r3cRatenzyme binding  IMP 2306167 RGD 
Ppp1r3cRatglycogen binding enablesIEAUniProtKB:Q7TMB3 and ensembl:ENSMUSP000000845781600115GO_REF:0000107EnsemblGO_REF:0000107
Ppp1r3cRatglycogen binding enablesISOPpp1r3c (Mus musculus)1624291 PMID:18852261RGDPMID:18852261
Ppp1r3cRatglycogen binding enablesIBAFB:FBgn0036428 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ppp1r3cRatmolecular adaptor activity enablesIEAUniProtKB:Q7TMB3 and ensembl:ENSMUSP000000845781600115GO_REF:0000107EnsemblGO_REF:0000107
Ppp1r3cRatmolecular adaptor activity enablesISOPpp1r3c (Mus musculus)1624291MGI:2662307 PMID:12727934 and PMID:9045612RGDPMID:12727934 and PMID:9045612
Ppp1r3cRatphosphoprotein phosphatase activity contributes_toIDA 2306167 RGD 
Ppp1r3cRatphosphoprotein phosphatase activity contributes_toIDA 2306166 RGD 
Ppp1r3cRatprotein binding enablesISOPPP1R3C (Homo sapiens)1624291UniProtKB:O95278 more ...RGDPMID:14532330 more ...
Ppp1r3cRatprotein phosphatase 1 binding enablesIBAFB:FBgn0036428 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ppp1r3cRatprotein phosphatase binding enablesIEAUniRule:UR0000285561600115GO_REF:0000104UniProtGO_REF:0000104
Ppp1r3cRatprotein phosphatase binding enablesIEAUniProtKB:Q7TMB3 and ensembl:ENSMUSP000000845781600115GO_REF:0000107EnsemblGO_REF:0000107
Ppp1r3cRatprotein phosphatase binding enablesISOPpp1r3c (Mus musculus)1624291PR:P62137 PMID:21471512RGDPMID:21471512
Ppp1r3cRatprotein phosphatase binding enablesISSUniProtKB:Q7TMB31600115GO_REF:0000024UniProtGO_REF:0000024
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RGD Manual Annotations


  
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Original Reference(s)
Ppp1r3cRatglycogen biosynthetic pathway   IDA 2306167 RGD 
Ppp1r3cRatglycogen degradation pathway   IDA 2306167 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
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Reference
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Original Reference(s)
Ppp1r3cRatinsulin signaling pathway   IEA 6907045 KEGGrno:04910

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#
Reference Title
Reference Citation
1. The level of the glycogen targetting regulatory subunit R5 of protein phosphatase 1 is decreased in the livers of insulin-dependent diabetic rats and starved rats. Browne GJ, etal., Biochem J. 2001 Dec 1;360(Pt 2):449-59.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. A novel glycogen-targeting subunit of protein phosphatase 1 that is regulated by insulin and shows differential tissue distribution in humans and rodents. Munro S, etal., FEBS J. 2005 Mar;272(6):1478-89.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
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PMID:9045612   PMID:10683377   PMID:12477932   PMID:15632090   PMID:18852261   PMID:21471512   PMID:21552327  



Ppp1r3c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81243,873,524 - 243,878,527 (-)NCBIGRCr8
mRatBN7.21234,460,958 - 234,465,961 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1234,460,652 - 234,465,961 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1242,855,971 - 242,860,979 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01249,778,292 - 249,783,285 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01242,616,484 - 242,621,477 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01255,371,830 - 255,376,833 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1255,371,810 - 255,376,833 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01262,628,937 - 262,633,940 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41240,991,884 - 240,996,887 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11241,175,278 - 241,180,280 (-)NCBI
Celera1231,556,257 - 231,561,260 (-)NCBICelera
Cytogenetic Map1q53NCBI
PPP1R3C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381091,628,442 - 91,633,071 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1091,628,442 - 91,633,071 (-)EnsemblGRCh38hg38GRCh38
GRCh371093,388,199 - 93,392,828 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361093,378,179 - 93,382,838 (-)NCBINCBI36Build 36hg18NCBI36
Build 341093,378,180 - 93,382,838NCBI
Celera1087,131,841 - 87,136,500 (-)NCBICelera
Cytogenetic Map10q23.32NCBI
HuRef1087,016,754 - 87,021,415 (-)NCBIHuRef
CHM1_11093,669,964 - 93,674,625 (-)NCBICHM1_1
T2T-CHM13v2.01092,511,668 - 92,516,296 (-)NCBIT2T-CHM13v2.0
Ppp1r3c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391936,709,131 - 36,714,004 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1936,709,131 - 36,714,053 (-)EnsemblGRCm39 Ensembl
GRCm381936,731,731 - 36,736,604 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1936,731,731 - 36,736,653 (-)EnsemblGRCm38mm10GRCm38
MGSCv371936,806,221 - 36,811,094 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361936,796,877 - 36,801,797 (-)NCBIMGSCv36mm8
Celera1937,506,440 - 37,511,313 (-)NCBICelera
Cytogenetic Map19C2NCBI
cM Map1931.89NCBI
Ppp1r3c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554251,606,069 - 1,611,586 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554251,606,069 - 1,611,001 (+)NCBIChiLan1.0ChiLan1.0
PPP1R3C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28103,668,222 - 103,673,064 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110103,673,537 - 103,678,379 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01088,377,396 - 88,382,205 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11091,900,112 - 91,904,764 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1091,900,112 - 91,904,764 (-)Ensemblpanpan1.1panPan2
PPP1R3C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1286,167,532 - 6,172,057 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl286,168,917 - 6,172,004 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha286,341,554 - 6,346,099 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0286,423,121 - 6,427,666 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl286,423,123 - 6,427,604 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1286,146,246 - 6,150,797 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0286,178,972 - 6,183,517 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0286,342,849 - 6,347,399 (-)NCBIUU_Cfam_GSD_1.0
Ppp1r3c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721341,297,720 - 41,302,426 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366012,930,208 - 2,935,092 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366012,930,250 - 2,935,024 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R3C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14103,273,405 - 103,278,762 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114103,273,401 - 103,278,757 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214112,652,689 - 112,657,293 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R3C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1984,918,592 - 84,923,281 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl984,918,591 - 84,923,334 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604845,645,616 - 45,650,669 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r3c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247372,893,256 - 2,901,452 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247372,896,677 - 2,901,393 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ppp1r3c
48 total Variants

Predicted Target Of
Summary Value
Count of predictions:518
Count of miRNA genes:249
Interacting mature miRNAs:304
Transcripts:ENSRNOT00000024941, ENSRNOT00000073381
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 75 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1214537555238757011Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat

1 to 10 of 75 rows
RH129209  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21234,460,983 - 234,461,163 (+)MAPPERmRatBN7.2
Rnor_6.01255,371,856 - 255,372,035NCBIRnor6.0
Rnor_5.01262,669,381 - 262,669,560UniSTSRnor5.0
Rnor_5.01262,628,963 - 262,629,142UniSTSRnor5.0
RGSC_v3.41240,991,910 - 240,992,089UniSTSRGSC3.4
Celera1231,556,283 - 231,556,462UniSTS
RH 3.4 Map11582.5UniSTS
Cytogenetic Map1q53UniSTS
RH138361  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21234,462,295 - 234,462,468 (+)MAPPERmRatBN7.2
Rnor_6.01255,373,168 - 255,373,340NCBIRnor6.0
Rnor_5.01262,670,693 - 262,670,865UniSTSRnor5.0
Rnor_5.01262,630,275 - 262,630,447UniSTSRnor5.0
RGSC_v3.41240,993,222 - 240,993,394UniSTSRGSC3.4
Celera1231,557,595 - 231,557,767UniSTS
RH 3.4 Map11582.1UniSTS
Cytogenetic Map1q53UniSTS
RH127645  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21234,461,029 - 234,461,216 (+)MAPPERmRatBN7.2
Rnor_6.01255,371,902 - 255,372,088NCBIRnor6.0
Rnor_5.01262,669,427 - 262,669,613UniSTSRnor5.0
Rnor_5.01262,629,009 - 262,629,195UniSTSRnor5.0
RGSC_v3.41240,991,956 - 240,992,142UniSTSRGSC3.4
Celera1231,556,329 - 231,556,515UniSTS
RH 3.4 Map11582.5UniSTS
Cytogenetic Map1q53UniSTS
RH140525  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21234,461,029 - 234,461,170 (+)MAPPERmRatBN7.2
Rnor_6.01255,371,902 - 255,372,042NCBIRnor6.0
Rnor_5.01262,669,427 - 262,669,567UniSTSRnor5.0
Rnor_5.01262,629,009 - 262,629,149UniSTSRnor5.0
RGSC_v3.41240,991,956 - 240,992,096UniSTSRGSC3.4
Celera1231,556,329 - 231,556,469UniSTS
RH 3.4 Map11583.0UniSTS
Cytogenetic Map1q53UniSTS
AA800273  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81243,873,763 - 243,873,968 (+)Marker Load Pipeline
mRatBN7.21234,461,197 - 234,461,402 (+)MAPPERmRatBN7.2
Rnor_6.01255,372,070 - 255,372,274NCBIRnor6.0
Rnor_5.01262,669,595 - 262,669,799UniSTSRnor5.0
Rnor_5.01262,629,177 - 262,629,381UniSTSRnor5.0
RGSC_v3.41240,992,124 - 240,992,328UniSTSRGSC3.4
Celera1231,556,497 - 231,556,701UniSTS
RH 3.4 Map11582.7UniSTS
Cytogenetic Map1q53UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000024941   ⟹   ENSRNOP00000024941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1234,460,962 - 234,465,961 (-)Ensembl
Rnor_6.0 Ensembl1255,371,810 - 255,376,833 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107925   ⟹   ENSRNOP00000082332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1234,460,652 - 234,465,837 (-)Ensembl
RefSeq Acc Id: NM_001012072   ⟹   NP_001012072
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81243,873,524 - 243,878,527 (-)NCBI
mRatBN7.21234,460,958 - 234,465,961 (-)NCBI
Rnor_6.01255,371,830 - 255,376,833 (-)NCBI
Rnor_5.01262,628,937 - 262,633,940 (-)NCBI
RGSC_v3.41240,991,884 - 240,996,887 (-)RGD
Celera1231,556,257 - 231,561,260 (-)RGD
Sequence:
Protein RefSeqs NP_001012072 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85894 (Get FASTA)   NCBI Sequence Viewer  
  EDM13188 (Get FASTA)   NCBI Sequence Viewer  
  Q5U2R5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001012072   ⟸   NM_001012072
- UniProtKB: Q5U2R5 (UniProtKB/Swiss-Prot),   A6I157 (UniProtKB/TrEMBL),   G3V8E0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024941   ⟸   ENSRNOT00000024941
Ensembl Acc Id: ENSRNOP00000082332   ⟸   ENSRNOT00000107925
CBM21

Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2R5-F1-model_v2 AlphaFold Q5U2R5 1-317 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690873
Promoter ID:EPDNEW_R1398
Type:single initiation site
Name:Ppp1r3c_1
Description:protein phosphatase 1, regulatory subunit 3C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01255,376,841 - 255,376,901EPDNEW


1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-55824 BioCyc
Ensembl Genes ENSRNOG00000018494 Ensembl
Gene3D-CATH 2.60.40.2440 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7192942 IMAGE-MGC_LOAD
InterPro CBM21_dom UniProtKB/Swiss-Prot
  CBM21_dom_sf UniProtKB/Swiss-Prot
  Pase-1_reg-su_3B/C/D_met UniProtKB/Swiss-Prot
  PP1_3C UniProtKB/Swiss-Prot
  PP1_regulatory_subunit_3 UniProtKB/Swiss-Prot
KEGG Report rno:309513 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94701 IMAGE-MGC_LOAD
NCBI Gene 309513 ENTREZGENE
PANTHER PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT UniProtKB/Swiss-Prot
  PTHR12307:SF15 UniProtKB/Swiss-Prot
Pfam CBM_21 UniProtKB/Swiss-Prot
PhenoGen Ppp1r3c PhenoGen
PIRSF PP1_GT_animal UniProtKB/Swiss-Prot
  PP1_PTG UniProtKB/Swiss-Prot
PROSITE CBM21 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018494 RatGTEx
UniProt A0A8I6G7A0_RAT UniProtKB/TrEMBL
  A6I157 ENTREZGENE, UniProtKB/TrEMBL
  G3V8E0 ENTREZGENE, UniProtKB/TrEMBL
  PPR3C_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-13 Ppp1r3c  protein phosphatase 1, regulatory subunit 3C  LOC100910671  protein phosphatase 1 regulatory subunit 3C-like  Data merged from RGD:6497444 737654 PROVISIONAL
2012-07-05 LOC100910671  protein phosphatase 1 regulatory subunit 3C-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2011-10-18 Ppp1r3c  protein phosphatase 1, regulatory subunit 3C  Ppp1r3c  protein phosphatase 1, regulatory (inhibitor) subunit 3C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ppp1r3c  protein phosphatase 1, regulatory (inhibitor) subunit 3C  Ppp1r3c_predicted  protein phosphatase 1, regulatory (inhibitor) subunit 3C (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ppp1r3c_predicted  protein phosphatase 1, regulatory (inhibitor) subunit 3C (predicted)      Symbol and Name status set to approved 70820 APPROVED