Gna14 (G protein subunit alpha 14) - Rat Genome Database

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Gene: Gna14 (G protein subunit alpha 14) Rattus norvegicus
Analyze
Symbol: Gna14
Name: G protein subunit alpha 14
RGD ID: 1308122
Description: Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in action potential; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; and phospholipase C-activating dopamine receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in cytoplasm. Orthologous to human GNA14 (G protein subunit alpha 14); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphaq protein family; eicosanoid signaling pathway; endothelin signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: guanine nucleotide binding protein, alpha 14; guanine nucleotide-binding protein subunit alpha-14; heterotrimeric guanine nucleotide-binding protein 1i; Hg1i; LOC309242; MGC105546; TGFB inducible early growth response 3; Tieg3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81223,141,802 - 223,324,210 (+)NCBIGRCr8
mRatBN7.21213,714,993 - 213,900,083 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1213,716,020 - 213,897,423 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1222,045,687 - 222,225,954 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01228,978,868 - 229,161,277 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,800,246 - 221,980,512 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01235,165,775 - 235,347,986 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1235,166,718 - 235,347,937 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01242,484,562 - 242,665,783 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41219,906,120 - 219,983,252 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1211,049,903 - 211,230,953 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gna14RatCEREBROFACIAL ARTERIOVENOUS METAMERIC SYNDROME  ISOGNA14 (Homo sapiens)8554872ClinVar Annotator: match by term: Cerebrofacial arteriovenous metameric syndromeClinVar 
Gna14Ratchoreaacanthocytosis  ISOGNA14 (Homo sapiens)8554872ClinVar Annotator: match by term: Chorea-acanthocytosisClinVarPMID:15918062
Gna14RatHigh Myopia  ISOGNA14 (Homo sapiens)8554872ClinVar Annotator: match by term: High myopiaClinVar 
Gna14RatKaposiform Hemangioendothelioma  ISOGNA14 (Homo sapiens)8554872ClinVar Annotator: match by term: Kaposiform hemangioendotheliomaClinVarPMID:25741868 and PMID:27476652
Gna14RatNeu-Laxova syndrome 2  ISOGNA14 (Homo sapiens)8554872ClinVar Annotator: match by term: Neu-Laxova syndrome 2ClinVarPMID:17436247 more ...
Gna14RatTufted Angioma  ISOGNA14 (Homo sapiens)8554872ClinVar Annotator: match by term: Tufted angiomaClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gna14RatExperimental Liver Cirrhosis  ISOGNA14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25380136

1 to 20 of 112 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gna14Rat1,1-dichloroethene decreases expressionISOGna14 (Mus musculus)6480464vinylidene chloride results in decreased expression of GNA14 mRNACTDPMID:26682919
Gna14Rat1,2-dimethylhydrazine multiple interactionsISOGna14 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GNA14 mRNACTDPMID:22206623
Gna14Rat1,3-dinitrobenzene increases expressionEXP 64804643-dinitrobenzene results in increased expression of GNA14 mRNACTDPMID:21983209
Gna14Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of GNA14 mRNACTDPMID:25380136
Gna14Rat17alpha-ethynylestradiol increases expressionISOGna14 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of GNA14 mRNACTDPMID:17942748
Gna14Rat17beta-estradiol multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in increased expression of GNA14 mRNACTDPMID:26496021
Gna14Rat17beta-estradiol decreases expressionISOGna14 (Mus musculus)6480464Estradiol results in decreased expression of GNA14 mRNACTDPMID:39298647
Gna14Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISOGna14 (Mus musculus)64804642 more ...CTDPMID:31388691
Gna14Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of GNA14 mRNACTDPMID:22298810
Gna14Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of GNA14 mRNACTDPMID:33387578
Gna14Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOGna14 (Mus musculus)6480464[Tetrachlorodibenzodioxin affects the methylation of GNA14 intron] which results in increased expression of GNA14 mRNACTDPMID:33017471
Gna14Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOGna14 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of GNA14 mRNACTDPMID:21570461 and PMID:26377647
Gna14Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOGna14 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of GNA14 mRNACTDPMID:19933214 and PMID:25975270
Gna14Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOGNA14 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of GNA14 mRNACTDPMID:23152189
Gna14Rat3,3',4,4',5-pentachlorobiphenyl increases expressionEXP 64804643 more ...CTDPMID:32119087
Gna14Rat3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone affects response to substanceISOGNA14 (Homo sapiens)6480464GNA14 gene SNP affects the susceptibility to 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanoneCTDPMID:25622337
Gna14Rat4,4'-diaminodiphenylmethane increases expressionEXP 64804644 and 4'-diaminodiphenylmethane results in increased expression of GNA14 mRNACTDPMID:25380136
Gna14Rat4,4'-sulfonyldiphenol increases expressionISOGna14 (Mus musculus)6480464bisphenol S results in increased expression of GNA14 mRNACTDPMID:30951980 and PMID:39298647
Gna14Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of GNA14 mRNACTDPMID:24780913 and PMID:30047161
Gna14Ratacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of GNA14 mRNACTDPMID:28959563

1 to 20 of 112 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gna14Rataction potential involved_inIBAMGI:95766 and PANTHER:PTN0083031901600115GO_REF:0000033GO_CentralGO_REF:0000033
Gna14Ratadenylate cyclase-modulating G protein-coupled receptor signaling pathway involved_inIBAMGI:95768 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gna14Ratbiological_process  ND 159840704/2014: no relevant rat dataRGD 
Gna14RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000654 and InterPro:IPR0010191600115GO_REF:0000002InterProGO_REF:0000002
Gna14Ratphospholipase C-activating dopamine receptor signaling pathway involved_inIBAMGI:95766 and PANTHER:PTN0000263961600115GO_REF:0000033GO_CentralGO_REF:0000033
Gna14Ratsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043
Gna14Ratsignal transduction involved_inIEAInterPro:IPR0110251600115GO_REF:0000002InterProGO_REF:0000002

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gna14Ratcytoplasm is_active_inIBAFB:FBgn0001104 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gna14Ratheterotrimeric G-protein complex part_ofIBACGD:CAL0000174954 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gna14Ratheterotrimeric G-protein complex part_ofIEAUniRule:UR0019337811600115GO_REF:0000104UniProtGO_REF:0000104

Molecular Function
1 to 16 of 16 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gna14RatG protein-coupled receptor binding enablesIEAInterPro:IPR0006541600115GO_REF:0000002InterProGO_REF:0000002
Gna14RatG protein-coupled receptor binding enablesIBAMGI:95770 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gna14RatG protein-coupled receptor binding enablesIEAUniRule:UR0019337811600115GO_REF:0000104UniProtGO_REF:0000104
Gna14RatG-protein beta/gamma-subunit complex binding enablesIEAUniRule:UR0019337811600115GO_REF:0000104UniProtGO_REF:0000104
Gna14RatG-protein beta/gamma-subunit complex binding enablesIBAMGI:95778 and PANTHER:PTN0000263921600115GO_REF:0000033GO_CentralGO_REF:0000033
Gna14RatG-protein beta/gamma-subunit complex binding enablesIEAInterPro:IPR0010191600115GO_REF:0000002InterProGO_REF:0000002
Gna14RatGTP binding enablesIEAUniRule:UR0019337811600115GO_REF:0000104UniProtGO_REF:0000104
Gna14RatGTP binding enablesIEAUniProtKB-KW:KW-03421600115GO_REF:0000043UniProtGO_REF:0000043
Gna14RatGTPase activity enablesIEAInterPro:IPR000654 and InterPro:IPR0010191600115GO_REF:0000002InterProGO_REF:0000002
Gna14RatGTPase activity enablesIEAUniRule:UR0019337811600115GO_REF:0000104UniProtGO_REF:0000104
Gna14RatGTPase activity enablesIBAMGI:3588268 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Gna14Ratguanyl nucleotide binding enablesIEAInterPro:IPR0010191600115GO_REF:0000002InterProGO_REF:0000002
Gna14Ratmetal ion binding enablesIEAUniRule:UR0019337811600115GO_REF:0000104UniProtGO_REF:0000104
Gna14Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Gna14Ratnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Gna14Ratprotein binding enablesISOGNA14 (Homo sapiens)1624291UniProtKB:O96015 more ...RGDPMID:25416956 and PMID:32814053
1 to 16 of 16 rows

RGD Manual Annotations


  

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gna14Ratcalcium/calcium-mediated signaling pathway   IEA 6907045 KEGGrno:04020
Gna14RatChagas disease pathway  IEA 6907045 KEGGrno:05142
Gna14RatEntamoebiasis pathway  IEA 6907045 KEGGrno:05146

Imported Annotations - PID (archival)


1 to 12 of 12 rows
#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Molecular properties of muscarinic acetylcholine receptors. Haga T Proc Jpn Acad Ser B Phys Biol Sci. 2013;89(6):226-56.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Regulation of phosphoinositide-specific phospholipase C. Rhee SG Annu Rev Biochem. 2001;70:281-312.
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
1 to 12 of 12 rows
PMID:23533145  



Gna14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81223,141,802 - 223,324,210 (+)NCBIGRCr8
mRatBN7.21213,714,993 - 213,900,083 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1213,716,020 - 213,897,423 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1222,045,687 - 222,225,954 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01228,978,868 - 229,161,277 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,800,246 - 221,980,512 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01235,165,775 - 235,347,986 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1235,166,718 - 235,347,937 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01242,484,562 - 242,665,783 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41219,906,120 - 219,983,252 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1211,049,903 - 211,230,953 (+)NCBICelera
Cytogenetic Map1q43NCBI
GNA14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38977,423,079 - 77,648,322 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl977,423,079 - 77,648,322 (-)EnsemblGRCh38hg38GRCh38
GRCh37980,037,995 - 80,263,238 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36979,228,368 - 79,453,043 (-)NCBINCBI36Build 36hg18NCBI36
Build 34977,268,102 - 77,492,777NCBI
Celera950,615,129 - 50,840,361 (-)NCBICelera
Cytogenetic Map9q21.2NCBI
HuRef949,869,436 - 50,095,508 (-)NCBIHuRef
CHM1_1980,184,787 - 80,410,463 (-)NCBICHM1_1
T2T-CHM13v2.0989,579,647 - 89,805,301 (-)NCBIT2T-CHM13v2.0
Gna14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391916,413,031 - 16,590,706 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1916,413,126 - 16,588,184 (+)EnsemblGRCm39 Ensembl
GRCm381916,435,667 - 16,610,818 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1916,435,762 - 16,610,820 (+)EnsemblGRCm38mm10GRCm38
MGSCv371916,510,157 - 16,685,308 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361916,502,781 - 16,677,839 (+)NCBIMGSCv36mm8
Celera1917,094,438 - 17,269,681 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map1911.29NCBI
Gna14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555121,707,503 - 1,917,513 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555121,703,750 - 1,918,321 (+)NCBIChiLan1.0ChiLan1.0
GNA14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21176,583,213 - 76,812,578 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1976,589,152 - 76,818,520 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0947,196,338 - 47,423,388 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1976,276,687 - 76,504,137 (-)NCBIpanpan1.1PanPan1.1panPan2
GNA14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1180,992,992 - 81,178,362 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl180,992,863 - 81,177,674 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha181,455,728 - 81,642,025 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0181,404,645 - 81,590,940 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl181,405,467 - 81,590,428 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1181,190,051 - 81,376,315 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0180,911,720 - 81,098,022 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0181,641,964 - 81,827,205 (+)NCBIUU_Cfam_GSD_1.0
LOC101971412
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947128,116,262 - 128,313,527 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650312,859,715 - 13,056,244 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650312,860,296 - 13,056,880 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNA14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1230,341,942 - 230,546,120 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11230,341,947 - 230,545,123 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21257,105,693 - 257,310,461 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GNA14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11288,386,597 - 88,606,787 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1288,385,377 - 88,605,845 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603876,717,968 - 76,939,040 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gna14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248114,909,324 - 5,108,322 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248114,904,428 - 5,108,713 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Gna14
1345 total Variants

Predicted Target Of
Summary Value
Count of predictions:500
Count of miRNA genes:238
Interacting mature miRNAs:288
Transcripts:ENSRNOT00000020201
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 92 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
8693637Alc29Alcohol consumption QTL 292.70.258drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1207987464234238494Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat

1 to 10 of 92 rows
RH142098  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81223,323,972 - 223,324,187 (+)Marker Load Pipeline
mRatBN7.21213,897,187 - 213,897,402 (+)MAPPERmRatBN7.2
Rnor_6.01235,347,702 - 235,347,916NCBIRnor6.0
Rnor_5.01242,665,546 - 242,665,760UniSTSRnor5.0
RGSC_v3.41219,983,015 - 219,983,229UniSTSRGSC3.4
Celera1211,230,716 - 211,230,930UniSTS
Cytogenetic Map1q43UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 38 105 91 90 59 25 59 6 207 86 85 45 60 31



Ensembl Acc Id: ENSRNOT00000020201   ⟹   ENSRNOP00000020201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1213,716,020 - 213,897,423 (+)Ensembl
Rnor_6.0 Ensembl1235,166,718 - 235,347,937 (+)Ensembl
RefSeq Acc Id: NM_001013151   ⟹   NP_001013169
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81223,141,802 - 223,324,210 (+)NCBI
mRatBN7.21213,714,993 - 213,897,425 (+)NCBI
Rnor_6.01235,166,718 - 235,347,939 (+)NCBI
Rnor_5.01242,484,562 - 242,665,783 (+)NCBI
RGSC_v3.41219,906,120 - 219,983,252 (+)RGD
Celera1211,049,903 - 211,230,953 (+)RGD
Sequence:
RefSeq Acc Id: XM_008760288   ⟹   XP_008758510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81223,141,811 - 223,324,210 (+)NCBI
mRatBN7.21213,714,993 - 213,900,083 (+)NCBI
Rnor_6.01235,165,775 - 235,347,986 (+)NCBI
Sequence:
Protein RefSeqs NP_001013169 (Get FASTA)   NCBI Sequence Viewer  
  XP_008758510 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH90316 (Get FASTA)   NCBI Sequence Viewer  
  CAG9553615 (Get FASTA)   NCBI Sequence Viewer  
  EDM12964 (Get FASTA)   NCBI Sequence Viewer  
  EDM12965 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020201
  ENSRNOP00000020201.7
RefSeq Acc Id: NP_001013169   ⟸   NM_001013151
- UniProtKB: Q5EAP4 (UniProtKB/TrEMBL),   F1LRE6 (UniProtKB/TrEMBL),   A0A8J8XRQ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008758510   ⟸   XM_008760288
- Peptide Label: isoform X1
- UniProtKB: Q5EAP4 (UniProtKB/TrEMBL),   F1LRE6 (UniProtKB/TrEMBL),   A0A8J8XRQ3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020201   ⟸   ENSRNOT00000020201

Name Modeler Protein Id AA Range Protein Structure
AF-Q5EAP4-F1-model_v2 AlphaFold Q5EAP4 1-355 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690808
Promoter ID:EPDNEW_R1333
Type:single initiation site
Name:Gna14_1
Description:G protein subunit alpha 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01235,166,712 - 235,166,772EPDNEW


1 to 30 of 30 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-56219 BioCyc
Ensembl Genes ENSRNOG00000014840 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020201 ENTREZGENE
  ENSRNOT00000020201.8 UniProtKB/TrEMBL
Gene3D-CATH 1.10.400.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7305112 IMAGE-MGC_LOAD
InterPro Gprotein_alpha_Q UniProtKB/TrEMBL
  Gprotein_alpha_su UniProtKB/TrEMBL
  GproteinA_insert UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:309242 UniProtKB/TrEMBL
MGC_CLONE MGC:105546 IMAGE-MGC_LOAD
NCBI Gene 309242 ENTREZGENE
PANTHER Gprotein_alph_bd UniProtKB/TrEMBL
  GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-14 UniProtKB/TrEMBL
Pfam G-alpha UniProtKB/TrEMBL
PhenoGen Gna14 PhenoGen
PRINTS GPROTEINA UniProtKB/TrEMBL
  GPROTEINAQ UniProtKB/TrEMBL
PROSITE G_ALPHA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014840 RatGTEx
SMART G_alpha UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  Transducn_insert UniProtKB/TrEMBL
UniProt A0A8J8XRQ3 ENTREZGENE, UniProtKB/TrEMBL
  A6I0I3_RAT UniProtKB/TrEMBL
  F1LRE6 ENTREZGENE
  Q5EAP4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1LRE6 UniProtKB/TrEMBL
1 to 30 of 30 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-11 Gna14  G protein subunit alpha 14  Gna14  guanine nucleotide binding protein, alpha 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Gna14  guanine nucleotide binding protein, alpha 14  Tieg3  TGFB inducible early growth response 3  Symbol and Name updated 1299863 APPROVED
2005-12-06 Tieg3  TGFB inducible early growth response 3  Tieg3_predicted  TGFB inducible early growth response 3 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tieg3_predicted  TGFB inducible early growth response 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED