Proc (protein C, inactivator of coagulation factors Va and VIIIa) - Rat Genome Database

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Gene: Proc (protein C, inactivator of coagulation factors Va and VIIIa) Chinchilla lanigera
Analyze
Symbol: Proc
Name: protein C, inactivator of coagulation factors Va and VIIIa
RGD ID: 8873519
Description: ENCODES a protein that exhibits oligopeptidase activity (ortholog); peptidase activity (ortholog); protein self-association (ortholog); INVOLVED IN liver development (ortholog); negative regulation of apoptotic process (ortholog); negative regulation of blood coagulation (ortholog); PARTICIPATES IN coagulation cascade pathway; protease mediated signaling via protease-activated receptor 1; protein C anticoagulant pathway; ASSOCIATED WITH Acute Experimental Pancreatitis (ortholog); acute kidney failure (ortholog); Acute Lung Injury (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: vitamin K-dependent protein C
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554593,094,120 - 3,104,135 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554593,097,229 - 3,105,566 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Proc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554593,094,120 - 3,104,135 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554593,097,229 - 3,105,566 (-)NCBIChiLan1.0ChiLan1.0
PROC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2127,418,427 - 127,429,242 (+)EnsemblGRCh38hg38GRCh38
GRCh382127,418,143 - 127,429,246 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372128,176,003 - 128,186,818 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362127,892,487 - 127,903,288 (+)NCBINCBI36hg18NCBI36
Build 342127,892,245 - 127,903,048NCBI
Celera2121,487,217 - 121,498,043 (+)NCBI
Cytogenetic Map2q14.3NCBI
HuRef2120,483,060 - 120,493,885 (+)NCBIHuRef
CHM1_12128,180,576 - 128,191,401 (+)NCBICHM1_1
Proc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391832,256,179 - 32,272,623 (-)NCBIGRCm39mm39
GRCm39 Ensembl1832,256,179 - 32,272,623 (-)Ensembl
GRCm381832,123,126 - 32,139,570 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1832,123,126 - 32,139,570 (-)EnsemblGRCm38mm10GRCm38
MGSCv371832,282,780 - 32,299,224 (-)NCBIGRCm37mm9NCBIm37
MGSCv361832,266,137 - 32,278,949 (-)NCBImm8
Celera1832,604,740 - 32,621,169 (-)NCBICelera
Cytogenetic Map18B1NCBI
Proc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21823,764,367 - 23,774,816 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1824,918,398 - 24,929,091 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01824,918,402 - 24,928,822 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01824,633,206 - 24,643,623 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41824,563,368 - 24,573,715 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11824,590,014 - 24,600,361 (-)NCBI
Celera1823,516,361 - 23,526,709 (-)NCBICelera
Cytogenetic Map18p12NCBI
PROC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B128,083,794 - 128,094,625 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B128,083,794 - 128,094,625 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B32,846,899 - 32,859,060 (-)NCBIMhudiblu_PPA_v0panPan3
PROC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11923,173,626 - 23,183,634 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1923,173,635 - 23,183,563 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1923,421,177 - 23,431,114 (-)NCBI
ROS_Cfam_1.01924,500,225 - 24,510,240 (-)NCBI
UMICH_Zoey_3.11923,203,858 - 23,213,794 (-)NCBI
UNSW_CanFamBas_1.01923,398,248 - 23,408,180 (-)NCBI
UU_Cfam_GSD_1.01924,530,694 - 24,540,633 (-)NCBI
Dog Cytomap19q21-q22NCBI
Proc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530397,765,920 - 97,775,831 (+)NCBI
SpeTri2.0NW_00493646943,841,989 - 43,850,322 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PROC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1525,032,622 - 25,056,595 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11525,043,543 - 25,054,310 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21528,724,914 - 28,735,638 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PROC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1102,789,227 - 2,799,783 (-)NCBI
ChlSab1.1 Ensembl102,789,277 - 2,799,531 (-)Ensembl
Vero_WHO_p1.0NW_02366606119,959,230 - 19,968,598 (+)NCBI
Proc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473213,915,361 - 13,922,182 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000003856   ⟹   ENSCLAP00000003780
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554593,094,120 - 3,104,135 (-)Ensembl
RefSeq Acc Id: XM_005397611   ⟹   XP_005397668
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554593,097,229 - 3,105,465 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005397612   ⟹   XP_005397669
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554593,097,229 - 3,105,464 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005397613   ⟹   XP_005397670
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554593,097,229 - 3,105,552 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005397614   ⟹   XP_005397671
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554593,097,229 - 3,105,566 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521066   ⟹   XP_013376520
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554593,097,229 - 3,105,465 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521067   ⟹   XP_013376521
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554593,097,229 - 3,105,566 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005397671   ⟸   XM_005397614
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005397670   ⟸   XM_005397613
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005397668   ⟸   XM_005397611
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005397669   ⟸   XM_005397612
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013376521   ⟸   XM_013521067
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013376520   ⟸   XM_013521066
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000003780   ⟸   ENSCLAT00000003856


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002690 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000003780 ENTREZGENE
Ensembl Transcript ENSCLAT00000003856 ENTREZGENE
NCBI Gene Proc ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Proc  protein C, inactivator of coagulation factors Va and VIIIa    protein C (inactivator of coagulation factors Va and VIIIa)  Symbol and/or name change 5135510 APPROVED