Kcnh1 (potassium voltage-gated channel subfamily H member 1) - Rat Genome Database

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Gene: Kcnh1 (potassium voltage-gated channel subfamily H member 1) Chinchilla lanigera
Analyze
Symbol: Kcnh1
Name: potassium voltage-gated channel subfamily H member 1
RGD ID: 8751829
Description: ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); calmodulin binding (ortholog); cyclic nucleotide binding (ortholog); INVOLVED IN cellular response to calcium ion (ortholog); monoatomic ion transmembrane transport (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); colorectal adenocarcinoma (ortholog); Developmental Disease (ortholog); FOUND IN axolemma (ortholog); axon (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium channel, voltage gated eag related subfamily H, member 1; potassium voltage-gated channel, subfamily H (eag-related), member 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554891,179,053 - 1,545,355 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554891,176,615 - 1,549,880 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554891,179,053 - 1,545,355 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554891,176,615 - 1,549,880 (+)NCBIChiLan1.0ChiLan1.0
KCNH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381210,678,314 - 211,134,148 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1210,676,823 - 211,134,165 (-)EnsemblGRCh38hg38GRCh38
GRCh371210,851,656 - 211,307,490 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361208,923,178 - 209,374,080 (-)NCBINCBI36Build 36hg18NCBI36
Build 341207,244,949 - 207,695,852NCBI
Celera1184,078,007 - 184,534,030 (-)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1181,528,354 - 181,984,466 (-)NCBIHuRef
CHM1_11212,124,419 - 212,580,029 (-)NCBICHM1_1
T2T-CHM13v2.01209,920,145 - 210,379,828 (-)NCBIT2T-CHM13v2.0
Kcnh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391191,871,759 - 192,192,467 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1191,873,082 - 192,192,467 (+)EnsemblGRCm39 Ensembl
GRCm381192,189,144 - 192,510,159 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1192,190,774 - 192,510,159 (+)EnsemblGRCm38mm10GRCm38
MGSCv371194,014,754 - 194,334,040 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361193,891,596 - 194,210,882 (+)NCBIMGSCv36mm8
Celera1199,081,917 - 199,396,846 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map197.33NCBI
Kcnh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813106,253,101 - 106,555,712 (+)NCBIGRCr8
mRatBN7.213103,722,140 - 104,024,762 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13103,722,245 - 104,024,740 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13106,242,159 - 106,544,653 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013107,626,002 - 107,928,502 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013104,840,996 - 105,143,620 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013110,920,712 - 111,232,291 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,920,737 - 111,232,269 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013115,478,526 - 115,789,705 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413108,129,617 - 108,407,815 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113108,318,724 - 108,596,919 (+)NCBI
Celera13103,160,967 - 103,461,850 (+)NCBICelera
Cytogenetic Map13q27NCBI
KCNH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2138,274,955 - 38,737,394 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1138,239,979 - 38,703,633 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01186,233,881 - 186,696,509 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11191,102,299 - 191,561,879 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1191,107,256 - 191,562,766 (-)Ensemblpanpan1.1panPan2
KCNH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.179,317,804 - 9,631,144 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl79,252,488 - 9,631,150 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha78,829,600 - 9,206,958 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.078,949,600 - 9,333,811 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl78,954,637 - 9,334,074 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.178,881,430 - 9,257,585 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.078,973,450 - 9,359,036 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.079,110,853 - 9,483,089 (-)NCBIUU_Cfam_GSD_1.0
Kcnh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934464,893,289 - 65,249,587 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365572,133,564 - 2,493,155 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365572,133,596 - 2,493,170 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9131,960,480 - 132,334,953 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19131,960,566 - 132,336,029 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29145,245,936 - 145,368,735 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12518,353,356 - 18,788,472 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2518,353,482 - 18,783,592 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605518,890,057 - 19,338,331 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248071,056,313 - 1,388,491 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248071,019,347 - 1,392,433 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005404511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005404512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013504482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01059830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01059842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDF01207581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000004404   ⟹   ENSCLAP00000004321
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554891,179,053 - 1,545,355 (+)Ensembl
RefSeq Acc Id: XM_005404511   ⟹   XP_005404568
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554891,176,615 - 1,549,880 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005404512   ⟹   XP_005404569
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554891,176,615 - 1,549,880 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013504482   ⟹   XP_013359936
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554891,211,994 - 1,549,880 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005404568 (Get FASTA)   NCBI Sequence Viewer  
  XP_005404569 (Get FASTA)   NCBI Sequence Viewer  
  XP_013359936 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000004321
  ENSCLAP00000004321.1
Reference Protein Sequences
RefSeq Acc Id: XP_005404568   ⟸   XM_005404511
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UWV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005404569   ⟸   XM_005404512
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013359936   ⟸   XM_013504482
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000004321   ⟸   ENSCLAT00000004404
Protein Domains
Cyclic nucleotide-binding   PAC   PAS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003074 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000004404 ENTREZGENE
  ENSCLAT00000004404.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1200.260 UniProtKB/TrEMBL
  1.10.287.70 UniProtKB/TrEMBL
  2.60.120.10 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro cNMP-bd-like UniProtKB/TrEMBL
  cNMP-bd_dom UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_EAG UniProtKB/TrEMBL
  K_chnl_volt-dep_EAG/ELK/ERG UniProtKB/TrEMBL
  PAC UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-assoc_C UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  RmlC-like_jellyroll UniProtKB/TrEMBL
NCBI Gene Kcnh1 ENTREZGENE
PANTHER PTHR10217:SF530 UniProtKB/TrEMBL
  VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL UniProtKB/TrEMBL
Pfam cNMP_binding UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
  PAS_9 UniProtKB/TrEMBL
PRINTS EAGCHANLFMLY UniProtKB/TrEMBL
  EAGCHANNEL UniProtKB/TrEMBL
PROSITE CNMP_BINDING_3 UniProtKB/TrEMBL
  PAC UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
SMART cNMP UniProtKB/TrEMBL
  PAC UniProtKB/TrEMBL
Superfamily-SCOP SSF51206 UniProtKB/TrEMBL
  SSF55785 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A8C2UWV0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Kcnh1  potassium voltage-gated channel subfamily H member 1    potassium channel, voltage gated eag related subfamily H, member 1  Symbol and/or name change 5135510 APPROVED
2015-08-25 Kcnh1  potassium channel, voltage gated eag related subfamily H, member 1    potassium voltage-gated channel, subfamily H (eag-related), member 1  Symbol and/or name change 5135510 APPROVED