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Gene: KCNH1 (potassium voltage-gated channel subfamily H member 1) Homo sapiens
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Symbol: KCNH1
Name: potassium voltage-gated channel subfamily H member 1
Description: Exhibits delayed rectifier potassium channel activity and phosphatidylinositol bisphosphate binding activity. Involved in several processes, including cellular response to calcium ion; phosphatidylinositol-mediated signaling; and potassium ion transmembrane transport. Localizes to the early endosome membrane; intracellular membrane-bounded organelle; and voltage-gated potassium channel complex. Implicated in colorectal adenocarcinoma. Biomarker of hepatocellular carcinoma and renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EAG; EAG channel 1; EAG1; ether-a-go-go potassium channel 1; ether-a-go-go, Drosophila, homolog of; h-eag; hEAG1; Kv10.1; MGC142269; potassium channel, voltage gated eag related subfamily H, member 1; potassium channel, voltage-gated, subfamily H, member 1; potassium voltage-gated channel subfamily H member 1 isoform E65; potassium voltage-gated channel subfamily H member 1 isoform E70; potassium voltage-gated channel, subfamily H (eag-related), member 1; TMBTS; voltage-gated potassium channel subunit Kv10.1; ZLS1
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381210,678,314 - 211,134,148 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371210,851,657 - 211,307,457 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361208,923,178 - 209,374,080 (-)NCBINCBI36hg18NCBI36
Build 341207,244,949 - 207,695,852NCBI
Celera1184,078,007 - 184,534,030 (-)NCBI
Cytogenetic Map1q32.2NCBI
HuRef1181,528,354 - 181,984,466 (-)NCBIHuRef
CHM1_11212,124,419 - 212,580,029 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

Nucleotide Sequences
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Nomenclature History
 
More on KCNH1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68584
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.