Symbol:
Nkx2-1
Name:
NK2 homeobox 1
RGD ID:
8746632
Description:
ENCODES a protein that exhibits core promoter sequence-specific DNA binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN anatomical structure formation involved in morphogenesis (ortholog); animal organ morphogenesis (ortholog); axon guidance (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH Benign Familial Chorea (ortholog); Brain-Lung-Thyroid Syndrome (ortholog); choreatic disease (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); transcription regulator complex (ortholog)
Type:
protein-coding
RefSeq Status:
MODEL
Previously known as:
homeobox protein Nkx-2.1
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955409 24,612,635 - 24,616,430 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955409 24,612,490 - 24,616,360 (+) NCBI ChiLan1.0 ChiLan1.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - PID (archival)
Nkx2-1 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955409 24,612,635 - 24,616,430 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955409 24,612,490 - 24,616,360 (+) NCBI ChiLan1.0 ChiLan1.0
NKX2-1 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 14 36,516,397 - 36,520,232 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 14 36,516,392 - 36,521,149 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 14 36,985,602 - 36,989,437 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 14 36,055,353 - 36,059,167 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 14 36,055,352 - 36,058,654 NCBI Celera 14 16,849,149 - 16,852,977 (-) NCBI Celera Cytogenetic Map 14 q13.3 NCBI HuRef 14 17,100,276 - 17,104,039 (-) NCBI HuRef CHM1_1 14 36,984,732 - 36,988,564 (-) NCBI CHM1_1 T2T-CHM13v2.0 14 30,705,671 - 30,709,516 (-) NCBI T2T-CHM13v2.0
Nkx2-1 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 12 56,578,741 - 56,583,570 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 12 56,578,743 - 56,583,693 (-) Ensembl GRCm39 Ensembl GRCm38 12 56,531,935 - 56,536,908 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 12 56,531,958 - 56,536,908 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 12 57,632,922 - 57,637,895 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 12 57,449,970 - 57,454,920 (-) NCBI MGSCv36 mm8 Celera 12 57,681,286 - 57,686,296 (-) NCBI Celera Cytogenetic Map 12 C1 NCBI cM Map 12 24.42 NCBI
Nkx2-1 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 6 79,731,677 - 79,735,952 (-) NCBI GRCr8 mRatBN7.2 6 73,996,601 - 74,001,483 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 6 73,996,601 - 73,999,791 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 6 74,392,972 - 74,396,162 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 6 74,699,372 - 74,702,565 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 6 74,126,847 - 74,130,040 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 6 77,418,096 - 77,423,383 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 6 77,418,096 - 77,421,286 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 6 86,945,224 - 86,950,040 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 6 76,916,943 - 76,920,133 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 6 76,920,108 - 76,923,259 (-) NCBI Celera 6 72,803,847 - 72,807,046 (-) NCBI Celera RH 3.4 Map 6 523.61 RGD Cytogenetic Map 6 q23 NCBI
LOC100983103 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 15 37,786,124 - 37,826,698 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 14 37,002,629 - 37,043,203 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 14 17,224,870 - 17,273,252 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 14 35,403,557 - 35,627,438 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 14 35,404,127 - 35,626,722 (-) Ensembl panpan1.1 panPan2
NKX2-1 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Dog10K_Boxer_Tasha 8 14,886,591 - 14,888,646 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 8 15,197,690 - 15,202,516 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 8 15,197,699 - 15,201,982 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 8 14,896,830 - 14,898,885 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 8 14,963,572 - 14,965,627 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 8 15,253,618 - 15,255,673 (-) NCBI UU_Cfam_GSD_1.0
Nkx2-1 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024408640 47,011,599 - 47,015,298 (-) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936494 10,517,488 - 10,520,566 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936494 10,517,488 - 10,520,567 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
NKX2-1 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 7 63,487,807 - 63,491,575 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 7 63,487,200 - 63,491,580 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 7 68,395,821 - 68,400,133 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
NKX2-1 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 24 13,274,118 - 13,317,533 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 24 13,310,846 - 13,317,056 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666053 2,266,777 - 2,311,899 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Nkx2-1
.
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
Ensembl Acc Id:
ENSCLAT00000016799 ⟹ ENSCLAP00000016635
Type:
CODING
Position:
Chinchilla Assembly Chr Position (strand) Source ChiLan1.0 Ensembl NW_004955409 24,612,635 - 24,616,430 (+) Ensembl
RefSeq Acc Id:
XM_005376911 ⟹ XP_005376968
Type:
CODING
Position:
Chinchilla Assembly Chr Position (strand) Source ChiLan1.0 NW_004955409 24,612,635 - 24,616,360 (+) NCBI
Sequence:
CCTCGGCCCCCTCTCCCCAAAGACCTGTCCGTGCCCGGGGAACCCCGACCACTTCGGAGAGTGGTTCCACTTTGTAACTCCTCAAGTTGGTTGCAAAGCAGCATTCACCTTCCTTCCTCCCCACCGTC
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RefSeq Acc Id:
XM_005376912 ⟹ XP_005376969
Type:
CODING
Position:
Chinchilla Assembly Chr Position (strand) Source ChiLan1.0 NW_004955409 24,612,490 - 24,616,360 (+) NCBI
Sequence:
TCTCTCTGGCTCCTTTGGTGGCGACTGGGGCTCGGCGCAGCGAAGCCCGATGTGGTGCGGAGGCAGTGGGAAGGCGCGGGGCTGGGAGGCCGCGGCGGGAGGGAGGAGCAGCCCCGGCAGGCTCAGCC
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RefSeq Acc Id:
XP_005376969 ⟸ XM_005376912
- Peptide Label:
isoform X2
- UniProtKB:
A0A8C2YQW0 (UniProtKB/TrEMBL)
- Sequence:
MWCGGSGKARGWEAAAGGRSSPGRLSRRRIMSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQGQAAPPAAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNLGNMSELP
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RefSeq Acc Id:
XP_005376968 ⟸ XM_005376911
- Peptide Label:
isoform X1
- UniProtKB:
A0A8C2YQW0 (UniProtKB/TrEMBL)
- Sequence:
MPRLWWLPKTWRRAKTNARQPPSLHSSQLRRTRSTPLRVHPTRSALSRRRIMSMSPKHTTPFSV
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Ensembl Acc Id:
ENSCLAP00000016635 ⟸ ENSCLAT00000016799
