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Gene: Unc13a (unc-13 homolog A) Rattus norvegicus
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Symbol: Unc13a
Name: unc-13 homolog A
RGD ID: 619722
Description: Exhibits several functions, including calmodulin binding activity; spectrin binding activity; and syntaxin-1 binding activity. Involved in exocytic process and modulation of chemical synaptic transmission. Localizes to several cellular components, including Golgi-associated vesicle; presynaptic active zone cytoplasmic component; and presynaptic membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human UNC13A (unc-13 homolog A); PARTICIPATES IN insulin secretion pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Munc13-1; protein unc-13 homolog A; unc-13 homolog A (C. elegans); Unc13h1
Orthologs:
Homo sapiens (human) : UNC13A (unc-13 homolog A)  HGNC  Alliance
Mus musculus (house mouse) : Unc13a (unc-13 homolog A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Unc13a (unc-13 homolog A)
Pan paniscus (bonobo/pygmy chimpanzee) : UNC13A (unc-13 homolog A)
Canis lupus familiaris (dog) : UNC13A (unc-13 homolog A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Unc13a (unc-13 homolog A)
Sus scrofa (pig) : UNC13A (unc-13 homolog A)
Chlorocebus sabaeus (African green monkey) : UNC13A (unc-13 homolog A)
Heterocephalus glaber (naked mole-rat) : Unc13a (unc-13 homolog A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01620,056,398 - 20,103,951 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,056,765 - 20,097,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,917,585 - 19,964,219 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,827,405 - 18,872,461 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11618,827,402 - 18,872,453 (-)NCBI
Celera1618,539,912 - 18,584,310 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Unc13a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619722
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.