UNC13A (unc-13 homolog A) - Rat Genome Database

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Gene: UNC13A (unc-13 homolog A) Chlorocebus sabaeus
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Symbol: UNC13A
Name: unc-13 homolog A
RGD ID: 18541377
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein domain specific binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN amyloid-beta metabolic process (ortholog); dense core granule docking (ortholog); innervation (ortholog); PARTICIPATES IN insulin secretion pathway; ASSOCIATED WITH amyotrophic lateral sclerosis type 1 (ortholog); autistic disorder (ortholog); cerebellar ataxia (ortholog); FOUND IN axon (ortholog); calyx of Held (ortholog); excitatory synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein unc-13 homolog A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,082,703 - 16,167,165 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,084,168 - 16,154,812 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660743,233,011 - 3,341,879 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UNC13A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,082,703 - 16,167,165 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,084,168 - 16,154,812 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660743,233,011 - 3,341,879 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
UNC13A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381917,601,336 - 17,688,354 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1917,601,336 - 17,688,365 (-)EnsemblGRCh38hg38GRCh38
GRCh371917,712,145 - 17,799,163 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361917,573,137 - 17,660,401 (-)NCBINCBI36Build 36hg18NCBI36
Celera1917,613,819 - 17,700,754 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1917,276,161 - 17,362,803 (-)NCBIHuRef
CHM1_11917,711,616 - 17,798,549 (-)NCBICHM1_1
T2T-CHM13v2.01917,735,579 - 17,822,489 (-)NCBIT2T-CHM13v2.0
Unc13a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39872,079,356 - 72,124,418 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl872,077,061 - 72,124,401 (-)EnsemblGRCm39 Ensembl
GRCm38871,624,125 - 71,671,774 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl871,624,417 - 71,671,757 (-)EnsemblGRCm38mm10GRCm38
MGSCv37874,150,611 - 74,195,656 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36874,558,412 - 74,600,636 (-)NCBIMGSCv36mm8
Celera874,140,993 - 74,186,237 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.43NCBI
Unc13a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,367,891 - 18,415,808 (-)NCBIGRCr8
mRatBN7.21618,333,910 - 18,381,813 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,336,229 - 18,381,872 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,384,673 - 18,432,402 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,516,945 - 19,565,015 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,437,617 - 18,485,341 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,056,398 - 20,103,951 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,056,765 - 20,097,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01619,917,585 - 19,964,219 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41618,827,405 - 18,872,461 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11618,827,402 - 18,872,453 (-)NCBI
Celera1618,539,912 - 18,584,310 (-)NCBICelera
Cytogenetic Map16p14NCBI
Unc13a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955524725,353 - 769,745 (+)NCBIChiLan1.0ChiLan1.0
UNC13A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22022,471,816 - 22,558,672 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11921,478,384 - 21,565,289 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,088,654 - 17,175,559 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,063,260 - 18,150,713 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,068,006 - 18,150,642 (-)Ensemblpanpan1.1panPan2
UNC13A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12045,179,275 - 45,237,544 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2045,188,750 - 45,238,115 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2045,091,418 - 45,152,586 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02045,664,551 - 45,729,225 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,664,566 - 45,726,706 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,900,707 - 44,962,114 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02045,311,011 - 45,375,605 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,586,777 - 45,648,193 (+)NCBIUU_Cfam_GSD_1.0
Unc13a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,763,514 - 203,824,246 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365963,312,788 - 3,368,916 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365963,311,358 - 3,370,833 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC13A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1260,057,926 - 60,130,015 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,626,729 - 59,665,341 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Unc13a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624908418,248 - 464,203 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Sequence


Ensembl Acc Id: ENSCSAT00000003538   ⟹   ENSCSAP00000001815
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl616,084,168 - 16,154,812 (-)Ensembl
RefSeq Acc Id: XM_007995731   ⟹   XP_007993922
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1616,082,703 - 16,167,164 (-)NCBI
Vero_WHO_p1.0NW_0236660743,233,041 - 3,341,879 (+)NCBI
Sequence:
RefSeq Acc Id: XM_007995736   ⟹   XP_007993927
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1616,082,703 - 16,167,164 (-)NCBI
Vero_WHO_p1.0NW_0236660743,233,011 - 3,337,168 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037992185   ⟹   XP_037848113
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660743,233,011 - 3,341,879 (+)NCBI
RefSeq Acc Id: XM_037992186   ⟹   XP_037848114
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660743,233,011 - 3,337,168 (+)NCBI
RefSeq Acc Id: XM_037992187   ⟹   XP_037848115
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660743,233,011 - 3,337,168 (+)NCBI
RefSeq Acc Id: XM_037992188   ⟹   XP_037848116
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660743,233,011 - 3,341,879 (+)NCBI
RefSeq Acc Id: XM_037992189   ⟹   XP_037848117
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_0236660743,233,011 - 3,341,879 (+)NCBI
RefSeq Acc Id: XP_007993927   ⟸   XM_007995736
- Peptide Label: isoform X7
- UniProtKB: A0A0D9QZM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007993922   ⟸   XM_007995731
- Peptide Label: isoform X1
- UniProtKB: A0A0D9QZM6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000001815   ⟸   ENSCSAT00000003538
RefSeq Acc Id: XP_037848117   ⟸   XM_037992189
- Peptide Label: isoform X6
- UniProtKB: A0A0D9QZM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037848113   ⟸   XM_037992185
- Peptide Label: isoform X2
- UniProtKB: A0A0D9QZM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037848116   ⟸   XM_037992188
- Peptide Label: isoform X5
- UniProtKB: A0A0D9QZM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037848114   ⟸   XM_037992186
- Peptide Label: isoform X3
- UniProtKB: A0A0D9QZM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037848115   ⟸   XM_037992187
- Peptide Label: isoform X4
- UniProtKB: A0A0D9QZM6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000005543 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000003538.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.50 UniProtKB/TrEMBL
  1.20.58.1100 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  CAPS_dom UniProtKB/TrEMBL
  Munc13_1 UniProtKB/TrEMBL
  Munc13_dom-2 UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  Unc-13 UniProtKB/TrEMBL
  Unc-13_C2B UniProtKB/TrEMBL
NCBI Gene UNC13A ENTREZGENE
PANTHER PTHR10480 UniProtKB/TrEMBL
  PTHR10480:SF1 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  DUF1041 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/TrEMBL
PROSITE MHD1 UniProtKB/TrEMBL
  MHD2 UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART DUF1041 UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A0D9QZM6 ENTREZGENE, UniProtKB/TrEMBL