TOMM22 (translocase of outer mitochondrial membrane 22) - Rat Genome Database

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Gene: TOMM22 (translocase of outer mitochondrial membrane 22) Homo sapiens
Analyze
Symbol: TOMM22
Name: translocase of outer mitochondrial membrane 22
RGD ID: 1342792
HGNC Page HGNC:18002
Description: Enables mitochondrion targeting sequence binding activity. Involved in protein insertion into mitochondrial outer membrane. Located in membrane and mitochondrion. Part of mitochondrial outer membrane translocase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 1C9-2; hTom22; mitochondrial import receptor subunit TOM22 homolog; mitochondrial import receptor Tom22; MST065; MSTP065; TOM22; translocase of outer membrane 22 kDa subunit homolog; translocase of outer mitochondrial membrane 22 homolog
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: TOMM22P1   TOMM22P2   TOMM22P3   TOMM22P4   TOMM22P5   TOMM22P6  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,681,957 - 38,685,421 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,681,957 - 38,685,421 (+)EnsemblGRCh38hg38GRCh38
GRCh372239,077,962 - 39,081,426 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,407,900 - 37,410,711 (+)NCBINCBI36Build 36hg18NCBI36
Build 342237,402,453 - 37,405,263NCBI
Celera2222,884,631 - 22,887,442 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2222,044,164 - 22,046,979 (+)NCBIHuRef
CHM1_12239,036,846 - 39,039,661 (+)NCBICHM1_1
T2T-CHM13v2.02239,152,160 - 39,155,628 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TOMM22Humanadenylosuccinase lyase deficiency  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Adenylosuccinate lyase deficiencyClinVarPMID:28492532
TOMM22HumanEmery-Dreifuss muscular dystrophy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Emery-Dreifuss muscular dystrophyClinVarPMID:16783378 more ...
TOMM22Humanmyoclonic dystonia 26  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Myoclonic dystonia 26ClinVarPMID:16783378 more ...
TOMM22Humanneurodegeneration with brain iron accumulation 2A  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Infantile neuroaxonal dystrophyClinVarPMID:16783378 more ...

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TOMM22Human(1->4)-beta-D-glucan multiple interactionsISOTomm22 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TOMM22 mRNACTDPMID:36331819
TOMM22Human2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOTomm22 (Mus musculus)64804642 more ...CTDPMID:30294300
TOMM22Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISOTomm22 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of TOMM22 mRNACTDPMID:21570461
TOMM22Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOTomm22 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of TOMM22 mRNACTDPMID:33387578
TOMM22Human2,6-dinitrotoluene affects expressionISOTomm22 (Rattus norvegicus)64804642 and 6-dinitrotoluene affects the expression of TOMM22 mRNACTDPMID:21346803
TOMM22Human2-hydroxypropanoic acid decreases expressionEXP 6480464Lactic Acid results in decreased expression of TOMM22 mRNACTDPMID:30851411
TOMM22Human3-chloropropane-1,2-diol increases expressionISOTomm22 (Rattus norvegicus)6480464alpha-Chlorohydrin results in increased expression of TOMM22 proteinCTDPMID:34915118
TOMM22Human4,4'-sulfonyldiphenol increases expressionISOTomm22 (Mus musculus)6480464bisphenol S results in increased expression of TOMM22 mRNACTDPMID:39298647
TOMM22Humanaconitine decreases expressionISOTomm22 (Rattus norvegicus)6480464Aconitine results in decreased expression of TOMM22 proteinCTDPMID:33236894
TOMM22Humanaflatoxin B1 increases expressionEXP 6480464Aflatoxin B1 results in increased expression of TOMM22 mRNACTDPMID:27153756
TOMM22Humanall-trans-retinoic acid decreases expressionEXP 6480464Tretinoin results in decreased expression of TOMM22 mRNACTDPMID:33167477
TOMM22Humanarsane multiple interactionsEXP 6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of TOMM22 mRNACTDPMID:39836092
TOMM22Humanarsenic atom multiple interactionsEXP 6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of TOMM22 mRNACTDPMID:39836092
TOMM22Humanarsenite(3-) decreases expressionISOTomm22 (Mus musculus)6480464arsenite results in decreased expression of TOMM22 mRNACTDPMID:33053406
TOMM22Humanarsenite(3-) multiple interactionsEXP 6480464arsenite promotes the reaction [G3BP1 protein binds to TOMM22 mRNA]CTDPMID:32406909
TOMM22Humanatrazine decreases expressionEXP 6480464Atrazine results in decreased expression of TOMM22 mRNACTDPMID:22378314
TOMM22Humanbeauvericin multiple interactionsEXP 6480464[beauvericin co-treated with enniatins] results in decreased expression of TOMM22 proteinCTDPMID:32407736
TOMM22Humanbenzo[a]pyrene decreases expressionISOTomm22 (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of TOMM22 mRNACTDPMID:27195522
TOMM22Humanbenzo[a]pyrene decreases expressionEXP 6480464Benzo(a)pyrene results in decreased expression of TOMM22 mRNACTDPMID:20106945
TOMM22Humanbisphenol A increases expressionISOTomm22 (Rattus norvegicus)6480464bisphenol A results in increased expression of TOMM22 mRNACTDPMID:25181051

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Biological Process

  

Cellular Component
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RGD Manual Annotations


  

#
Reference Title
Reference Citation
1. Biogenesis of mitochondrial outer membrane proteins, problems and diseases. Ellenrieder L, etal., Biol Chem. 2015 Oct 1;396(11):1199-213. doi: 10.1515/hsz-2015-0170.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. Assembly of beta-barrel proteins in the mitochondrial outer membrane. Hohr AI, etal., Biochim Biophys Acta. 2015 Jan;1853(1):74-88. doi: 10.1016/j.bbamcr.2014.10.006. Epub 2014 Oct 8.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Unlocking the presequence import pathway. Schulz C, etal., Trends Cell Biol. 2015 May;25(5):265-75. doi: 10.1016/j.tcb.2014.12.001. Epub 2014 Dec 23.
7. Cooperation of protein machineries in mitochondrial protein sorting. Wenz LS, etal., Biochim Biophys Acta. 2015 May;1853(5):1119-29. doi: 10.1016/j.bbamcr.2015.01.012. Epub 2015 Jan 26.
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PMID:8125298   PMID:10900208   PMID:10980201   PMID:10982837   PMID:12198123   PMID:12477932   PMID:14557246   PMID:14699115   PMID:14702039   PMID:15461802   PMID:15489334   PMID:15644312  
PMID:16712791   PMID:17081983   PMID:17096026   PMID:17635912   PMID:18029348   PMID:18331822   PMID:19322201   PMID:19946888   PMID:20877624   PMID:22119785   PMID:22178394   PMID:22198199  
PMID:22280891   PMID:22939629   PMID:23503661   PMID:23874603   PMID:24149440   PMID:24797263   PMID:24886575   PMID:24981860   PMID:24999758   PMID:25416956   PMID:25556234   PMID:25591737  
PMID:25678554   PMID:25739811   PMID:25852190   PMID:26344197   PMID:26496610   PMID:26752685   PMID:26787839   PMID:26949251   PMID:26972000   PMID:27025967   PMID:27173435   PMID:27280685  
PMID:27432908   PMID:27499296   PMID:27592226   PMID:28302793   PMID:28514442   PMID:28515276   PMID:28869606   PMID:29128334   PMID:29360040   PMID:29509190   PMID:29509794   PMID:29568061  
PMID:29778605   PMID:29955894   PMID:30033366   PMID:30194290   PMID:30463901   PMID:30884312   PMID:31073040   PMID:31091453   PMID:31527615   PMID:31536960   PMID:31586073   PMID:31980649  
PMID:31995728   PMID:32060556   PMID:32203420   PMID:32296183   PMID:32807901   PMID:32814053   PMID:32877691   PMID:33567341   PMID:33961781   PMID:34037656   PMID:34079125   PMID:34373451  
PMID:34687317   PMID:34709727   PMID:34800366   PMID:35073964   PMID:35271311   PMID:35384245   PMID:35439318   PMID:35733257   PMID:35844135   PMID:35941108   PMID:36180527   PMID:36215168  
PMID:36273042   PMID:36654301   PMID:37223481   PMID:37267103   PMID:37314216   PMID:37317656   PMID:37528093   PMID:37616343   PMID:37667382   PMID:37697039   PMID:37820061   PMID:37827155  
PMID:37878010   PMID:38569033   PMID:38580884  
1 to 10 of 10 rows



TOMM22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382238,681,957 - 38,685,421 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2238,681,957 - 38,685,421 (+)EnsemblGRCh38hg38GRCh38
GRCh372239,077,962 - 39,081,426 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362237,407,900 - 37,410,711 (+)NCBINCBI36Build 36hg18NCBI36
Build 342237,402,453 - 37,405,263NCBI
Celera2222,884,631 - 22,887,442 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2222,044,164 - 22,046,979 (+)NCBIHuRef
CHM1_12239,036,846 - 39,039,661 (+)NCBICHM1_1
T2T-CHM13v2.02239,152,160 - 39,155,628 (+)NCBIT2T-CHM13v2.0
Tomm22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391579,555,069 - 79,557,063 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1579,555,062 - 79,557,601 (+)EnsemblGRCm39 Ensembl
GRCm381579,670,868 - 79,672,862 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1579,670,861 - 79,673,400 (+)EnsemblGRCm38mm10GRCm38
MGSCv371579,501,298 - 79,503,292 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361579,498,123 - 79,500,117 (+)NCBIMGSCv36mm8
Celera1581,796,265 - 81,798,069 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.85NCBI
Tomm22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87113,103,863 - 113,109,056 (+)NCBIGRCr8
mRatBN7.27111,223,508 - 111,228,671 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,216,571 - 111,246,799 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7112,974,658 - 112,976,408 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07115,198,199 - 115,199,949 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07115,167,574 - 115,169,324 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07120,901,934 - 120,903,684 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7120,901,934 - 120,903,684 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07120,888,909 - 120,894,057 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47117,913,211 - 117,914,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17117,947,453 - 117,948,603 (+)NCBI
Celera7107,557,387 - 107,559,137 (+)NCBICelera
Cytogenetic Map7q34NCBI
Tomm22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541324,799,735 - 24,801,820 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541324,799,735 - 24,801,820 (+)NCBIChiLan1.0ChiLan1.0
TOMM22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22348,537,569 - 48,540,122 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12251,228,944 - 51,231,496 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02219,596,941 - 19,599,499 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12237,414,704 - 37,417,229 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2237,414,704 - 37,417,229 (+)Ensemblpanpan1.1panPan2
TOMM22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11026,116,635 - 26,118,692 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1026,072,167 - 26,074,221 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01026,907,763 - 26,909,817 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1026,907,769 - 26,909,795 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,629,429 - 26,631,481 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01026,940,542 - 26,942,596 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01027,117,431 - 27,119,486 (-)NCBIUU_Cfam_GSD_1.0
Tomm22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049459,660,052 - 9,662,052 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364922,671,076 - 2,672,446 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364922,670,734 - 2,672,463 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOMM22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl59,336,130 - 9,350,015 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.159,336,114 - 9,339,867 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,579,626 - 6,581,626 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TOMM22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11921,344,846 - 21,347,709 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1921,344,865 - 21,347,264 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045104,411,154 - 104,414,022 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tomm22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247529,464,412 - 9,466,874 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247529,464,412 - 9,466,896 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in TOMM22
11 total Variants

1 to 10 of 43 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 22q12.3-13.1(chr22:35333993-38900177)x1 copy number loss See cases [RCV000051364] Chr22:35333993..38900177 [GRCh38]
Chr22:35729986..39296182 [GRCh37]
Chr22:34059986..37626128 [NCBI36]
Chr22:22q12.3-13.1
pathogenic
GRCh38/hg38 22q12.3-13.1(chr22:36859030-39236985)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051366]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051366]|See cases [RCV000051366] Chr22:36859030..39236985 [GRCh38]
Chr22:37255072..39632990 [GRCh37]
Chr22:35585018..37962936 [NCBI36]
Chr22:22q12.3-13.1
pathogenic
GRCh38/hg38 22q13.1(chr22:37721777-38886664)x1 copy number loss See cases [RCV000051367] Chr22:37721777..38886664 [GRCh38]
Chr22:38117784..39282669 [GRCh37]
Chr22:36447730..37612615 [NCBI36]
Chr22:22q13.1
pathogenic
GRCh38/hg38 22q12.3-13.33(chr22:33768441-50739977)x3 copy number gain See cases [RCV000051682] Chr22:33768441..50739977 [GRCh38]
Chr22:34164428..51178405 [GRCh37]
Chr22:32494428..49525271 [NCBI36]
Chr22:22q12.3-13.33
pathogenic
GRCh38/hg38 22q12.3-13.33(chr22:37061769-50738932)x3 copy number gain See cases [RCV000051684] Chr22:37061769..50738932 [GRCh38]
Chr22:37457809..51177360 [GRCh37]
Chr22:35787755..49524226 [NCBI36]
Chr22:22q12.3-13.33
pathogenic
GRCh38/hg38 22q13.1-13.2(chr22:37721797-40860953)x3 copy number gain See cases [RCV000051685] Chr22:37721797..40860953 [GRCh38]
Chr22:38117804..41256957 [GRCh37]
Chr22:36447750..39586903 [NCBI36]
Chr22:22q13.1-13.2
pathogenic
NM_014876.5(JOSD1):c.438G>A (p.Val146=) single nucleotide variant Malignant melanoma [RCV000072969] Chr22:38689006 [GRCh38]
Chr22:39085011 [GRCh37]
Chr22:37414957 [NCBI36]
Chr22:22q13.1
not provided
GRCh38/hg38 22q11.1-13.33(chr22:16916608-50739836)x3 copy number gain See cases [RCV000133646] Chr22:16916608..50739836 [GRCh38]
Chr22:17397498..51178264 [GRCh37]
Chr22:15777498..49525130 [NCBI36]
Chr22:22q11.1-13.33
pathogenic
GRCh38/hg38 22q11.1-13.33(chr22:16916743-50739785)x3 copy number gain See cases [RCV000134730] Chr22:16916743..50739785 [GRCh38]
Chr22:17397633..51178213 [GRCh37]
Chr22:15777633..49525079 [NCBI36]
Chr22:22q11.1-13.33
pathogenic
GRCh38/hg38 22q13.1(chr22:37447222-39103680)x1 copy number loss See cases [RCV000141783] Chr22:37447222..39103680 [GRCh38]
Chr22:37843259..39499685 [GRCh37]
Chr22:36173205..37829631 [NCBI36]
Chr22:22q13.1
pathogenic
1 to 10 of 43 rows

Predicted Target Of
Summary Value
Count of predictions:723
Count of miRNA genes:438
Interacting mature miRNAs:474
Transcripts:ENST00000216034, ENST00000492561
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
406978375GWAS627351_Hhemoglobin measurement QTL GWAS627351 (human)1e-14hemoglobin measurementhemoglobin measurement (CMO:0000508)223868463338684634Human

WI-20226  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372239,080,176 - 39,080,460UniSTSGRCh37
Build 362237,410,122 - 37,410,406RGDNCBI36
Celera2222,886,853 - 22,887,137RGD
Cytogenetic Map22q12-q13UniSTS
HuRef2222,046,390 - 22,046,674UniSTS
GeneMap99-GB4 RH Map22131.23UniSTS
Whitehead-RH Map22129.9UniSTS
NCBI RH Map22154.0UniSTS
RH17776  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map22q12-q13UniSTS
GeneMap99-GB4 RH Map13107.14UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7306 6472 53 3734 1 852 1744 1617 175 1



Ensembl Acc Id: ENST00000216034   ⟹   ENSP00000216034
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2238,681,957 - 38,685,421 (+)Ensembl
Ensembl Acc Id: ENST00000492561
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2238,682,172 - 38,684,160 (+)Ensembl
RefSeq Acc Id: NM_020243   ⟹   NP_064628
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382238,681,957 - 38,685,421 (+)NCBI
GRCh372239,077,954 - 39,080,765 (+)RGD
Build 362237,407,900 - 37,410,711 (+)NCBI Archive
Celera2222,884,631 - 22,887,442 (+)RGD
HuRef2222,044,164 - 22,046,979 (+)RGD
CHM1_12239,036,846 - 39,039,661 (+)NCBI
T2T-CHM13v2.02239,152,160 - 39,155,628 (+)NCBI
Sequence:
RefSeq Acc Id: NP_064628   ⟸   NM_020243
- UniProtKB: Q9NS69 (UniProtKB/Swiss-Prot),   Q549C5 (UniProtKB/TrEMBL),   Q53GB0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000216034   ⟸   ENST00000216034

Name Modeler Protein Id AA Range Protein Structure
AF-Q9NS69-F1-model_v2 AlphaFold Q9NS69 1-142 view protein structure

RGD ID:6800447
Promoter ID:HG_KWN:42831
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000320831,   OTTHUMT00000320842,   OTTHUMT00000320843,   OTTHUMT00000321036,   OTTHUMT00000321038
Position:
Human AssemblyChrPosition (strand)Source
Build 362237,407,681 - 37,408,181 (+)MPROMDB
RGD ID:6850836
Promoter ID:EP73213
Type:initiation region
Name:HS_TOMM22
Description:Translocase of outer mitochondrial membrane 22 homolog (yeast).
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 362237,407,926 - 37,407,986EPD
RGD ID:13604074
Promoter ID:EPDNEW_H28222
Type:initiation region
Name:TOMM22_1
Description:translocase of outer mitochondrial membrane 22
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H28221  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382238,681,975 - 38,682,035EPDNEW


1 to 18 of 18 rows
Database
Acc Id
Source(s)
COSMIC TOMM22 COSMIC
Ensembl Genes ENSG00000100216 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000216034 ENTREZGENE
  ENST00000216034.6 UniProtKB/Swiss-Prot
GTEx ENSG00000100216 GTEx
HGNC ID HGNC:18002 ENTREZGENE
Human Proteome Map TOMM22 Human Proteome Map
InterPro Tom22 UniProtKB/Swiss-Prot
KEGG Report hsa:56993 UniProtKB/Swiss-Prot
NCBI Gene 56993 ENTREZGENE
OMIM 607046 OMIM
PANTHER MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG UniProtKB/Swiss-Prot
  PTHR12504 UniProtKB/Swiss-Prot
Pfam Tom22 UniProtKB/Swiss-Prot
PharmGKB PA38275 PharmGKB
UniProt Q53GB0 ENTREZGENE, UniProtKB/TrEMBL
  Q549C5 ENTREZGENE, UniProtKB/TrEMBL
  Q9NS69 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 18 of 18 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 TOMM22  translocase of outer mitochondrial membrane 22  TOMM22  translocase of outer mitochondrial membrane 22 homolog (yeast)  Symbol and/or name change 5135510 APPROVED