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Gene: Wnt10b (wingless-type MMTV integration site family, member 10B) Mus musculus
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Symbol: Wnt10b
Name: wingless-type MMTV integration site family, member 10B
Description: Predicted to have cytokine activity and frizzled binding activity. Involved in several processes, including animal organ development; positive regulation of ossification; and regulation of transcription, DNA-templated. Predicted to localize to extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and surface ectoderm. Human ortholog(s) of this gene implicated in obesity; split hand-foot malformation 6; and tooth agenesis. Orthologous to human WNT10B (Wnt family member 10B); PARTICIPATES IN Wnt signaling, canonical pathway; basal cell carcinoma pathway; Hedgehog signaling pathway; INTERACTS WITH 1,2-dichloroethane; 15-deoxy-Delta(12,14)-prostaglandin J2; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: protein Wnt-10b; wingless related MMTV integration site 10b; wnt-12; Wnt12
Orthologs:
Homo sapiens (human) : WNT10B (Wnt family member 10B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Wnt10b (Wnt family member 10B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wnt10b (Wnt family member 10B)
Pan paniscus (bonobo/pygmy chimpanzee) : WNT10B (Wnt family member 10B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnt10b (Wnt family member 10B)
Sus scrofa (pig) : WNT10B (Wnt family member 10B)
Chlorocebus sabaeus (African green monkey) : WNT10B (Wnt family member 10B)
Heterocephalus glaber (naked mole-rat) : Wnt10b (Wnt family member 10B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1598,770,712 - 98,778,150 (-)EnsemblGRCm38mm10GRCm38
GRCm381598,770,712 - 98,778,206 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371598,602,183 - 98,608,581 (-)NCBIGRCm37mm9NCBIm37
MGSCv361598,599,796 - 98,606,184 (-)NCBImm8
Celera15100,921,391 - 100,927,785 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1554.65NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Wnt10b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312745
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.