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Gene: Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1) Rattus norvegicus
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Symbol: Hoga1
Name: 4-hydroxy-2-oxoglutarate aldolase 1
Description: Predicted to have 4-hydroxy-2-oxoglutarate aldolase activity and protein homodimerization activity. Predicted to be involved in carboxylic acid metabolic process. Human ortholog(s) of this gene implicated in primary hyperoxaluria. Orthologous to human HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Dhdpsl; dihydrodipicolinate synthase-like, mitochondrial; LOC293949; N-acetylneuraminate pyruvate lyase 2 (putative); Npl2; probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; RGD1310475; similar to RIKEN cDNA 0610010D20
Orthologs:
Homo sapiens (human) : HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1)  HGNC  Alliance
Mus musculus (house mouse) : Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1)
Canis lupus familiaris (dog) : HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1)
Sus scrofa (pig) : HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01261,291,742 - 261,319,743 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1261,291,870 - 261,318,984 (+)Ensembl
Rnor_5.01268,744,219 - 268,772,215 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41248,779,289 - 248,806,403 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11249,038,615 - 249,065,045 (-)NCBI
Celera1236,691,611 - 236,718,741 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Hoga1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310475
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.