Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1) - Rat Genome Database

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Gene: Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1) Heterocephalus glaber
Analyze
Symbol: Hoga1
Name: 4-hydroxy-2-oxoglutarate aldolase 1
RGD ID: 18925004
Description: ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN 4-hydroxyproline catabolic process (ortholog); glyoxylate metabolic process (ortholog); oxalate metabolic process (ortholog); ASSOCIATED WITH cholestasis (ortholog); genetic disease (ortholog); primary hyperoxaluria (ortholog); FOUND IN mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Dihydrodipicolinate synthase-like, mitochondrial; putative 4-hydroxy-2-oxoglutarate aldolase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247379,228,605 - 9,254,024 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247379,228,748 - 9,258,136 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Hoga1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247379,228,605 - 9,254,024 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247379,228,748 - 9,258,136 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HOGA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381097,584,389 - 97,612,802 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1097,584,323 - 97,612,802 (+)EnsemblGRCh38hg38GRCh38
GRCh371099,344,146 - 99,372,559 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361099,334,108 - 99,362,549 (+)NCBINCBI36Build 36hg18NCBI36
Build 341099,334,110 - 99,362,543NCBI
Celera1093,081,405 - 93,109,870 (+)NCBICelera
Cytogenetic Map10q24.2NCBI
HuRef1092,970,152 - 92,998,506 (+)NCBIHuRef
CHM1_11099,625,834 - 99,654,292 (+)NCBICHM1_1
T2T-CHM13v2.01098,464,572 - 98,493,008 (+)NCBIT2T-CHM13v2.0
Hoga1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391942,033,998 - 42,060,128 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1942,034,049 - 42,059,392 (+)EnsemblGRCm39 Ensembl
GRCm381942,045,559 - 42,071,689 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1942,045,610 - 42,070,953 (+)EnsemblGRCm38mm10GRCm38
MGSCv371942,120,341 - 42,145,429 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361942,099,162 - 42,124,250 (+)NCBIMGSCv36mm8
Celera1942,849,723 - 42,874,820 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1935.67NCBI
Hoga1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81250,806,430 - 250,833,544 (+)NCBIGRCr8
mRatBN7.21240,856,991 - 240,884,243 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1240,857,126 - 240,884,568 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1249,002,512 - 249,029,695 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01255,699,654 - 255,726,828 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01248,352,684 - 248,379,857 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01261,291,742 - 261,319,743 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1261,291,870 - 261,318,984 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01268,744,219 - 268,772,215 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41248,779,289 - 248,806,403 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11249,038,615 - 249,065,045 (-)NCBI
Celera1236,691,611 - 236,718,741 (+)NCBICelera
Cytogenetic Map1q54NCBI
Hoga1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555073,687,769 - 3,711,151 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555073,687,449 - 3,711,939 (+)NCBIChiLan1.0ChiLan1.0
HOGA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28109,496,181 - 109,524,859 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110109,501,500 - 109,531,789 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01094,204,627 - 94,233,312 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11097,697,683 - 97,726,289 (+)NCBIpanpan1.1PanPan1.1panPan2
HOGA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12810,849,037 - 10,872,238 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2810,849,046 - 10,871,853 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2811,033,727 - 11,060,294 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02811,173,637 - 11,200,481 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2811,173,896 - 11,197,428 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12810,834,716 - 10,859,086 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02810,895,424 - 10,922,168 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02811,035,386 - 11,061,987 (+)NCBIUU_Cfam_GSD_1.0
Hoga1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721336,062,068 - 36,085,956 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366362,102,036 - 2,125,532 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366362,101,184 - 2,125,377 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOGA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14108,958,973 - 108,986,707 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114108,958,812 - 108,986,373 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214118,462,772 - 118,490,341 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOGA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1990,745,969 - 90,772,953 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl990,746,373 - 90,773,932 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604851,644,096 - 51,671,723 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000015320   ⟹   ENSHGLP00000015165
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247379,228,605 - 9,254,024 (+)Ensembl
RefSeq Acc Id: XM_004838605   ⟹   XP_004838662
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247379,228,748 - 9,254,827 (+)NCBI
RefSeq Acc Id: XM_004838606   ⟹   XP_004838663
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247379,229,027 - 9,258,136 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004838662 (Get FASTA)   NCBI Sequence Viewer  
  XP_004838663 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB14972 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000015165
GenBank Protein JAN96688 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004838662   ⟸   XM_004838605
- UniProtKB: G5C0B9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004838663   ⟸   XM_004838606
- UniProtKB: G5C0B9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000015165   ⟸   ENSHGLT00000015320


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010861 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000015320 ENTREZGENE
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/TrEMBL
  DapA-like UniProtKB/TrEMBL
  Schiff_base-form_aldolases_AS UniProtKB/TrEMBL
  Schiff_base-form_aldolases_CS UniProtKB/TrEMBL
KEGG Report hgl:101700602 UniProtKB/TrEMBL
NCBI Gene Hoga1 ENTREZGENE
PANTHER 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR12128 UniProtKB/TrEMBL
Pfam DHDPS UniProtKB/TrEMBL
PIRSF DHDPS UniProtKB/TrEMBL
PRINTS DHPICSNTHASE UniProtKB/TrEMBL
PROSITE DHDPS_1 UniProtKB/TrEMBL
  DHDPS_2 UniProtKB/TrEMBL
SMART DHDPS UniProtKB/TrEMBL
Superfamily-SCOP Aldolase UniProtKB/TrEMBL
UniProt G5C0B9 ENTREZGENE, UniProtKB/TrEMBL