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Gene: Xpc (XPC complex subunit, DNA damage recognition and repair factor) Rattus norvegicus
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Symbol: Xpc
Name: XPC complex subunit, DNA damage recognition and repair factor
Description: Predicted to have damaged DNA binding activity and single-stranded DNA binding activity. Involved in response to auditory stimulus and response to drug. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer; serous cystadenocarcinoma; xeroderma pigmentosum; and xeroderma pigmentosum group C. Orthologous to human XPC (XPC complex subunit, DNA damage recognition and repair factor); PARTICIPATES IN altered nucleotide excision repair pathway; nucleotide excision repair pathway; INTERACTS WITH (RS)-amphetamine; bisphenol A; buspirone.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA repair protein complementing XP-C cells; LOC312560; xeroderma pigmentosum, complementation group C
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04123,134,457 - 123,161,985 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04187,383,715 - 187,411,243 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44125,672,674 - 125,699,925 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14125,917,926 - 125,944,347 (-)NCBI
Celera4112,913,130 - 112,940,381 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Xpc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305760
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.