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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305760
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Xpc
Name: XPC complex subunit, DNA damage recognition and repair factor
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xpcincreases expressionISOXPC (Homo sapiens)6480464CTDOzone results in increased expression of XPC mRNAPMID:27206323
Xpcmultiple interactionsISOXPC (Homo sapiens)6480464CTD[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of XPC mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of XPC mRNA; [Volatile Organic Compounds co-treated with Ozone] results in increased oxidation of XPC mRNAPMID:32699268
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