ID1 (inhibitor of DNA binding 1) - Rat Genome Database

Name: ID1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: ID1 (inhibitor of DNA binding 1) Pan paniscus

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Symbol:

ID1

Name:

inhibitor of DNA binding 1

RGD ID:

11817453

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); proteasome binding (ortholog); transcription factor binding (ortholog); INVOLVED IN apoptotic process (ortholog); BMP signaling pathway (ortholog); cell-abiotic substrate adhesion (ortholog); PARTICIPATES IN interleukin-3 signaling pathway; ASSOCIATED WITH cholestasis (ortholog); disease of cellular proliferation (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN centrosome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

DNA-binding protein inhibitor ID-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	37,296,445 - 37,299,392 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	37,290,399 - 37,292,483 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	27,895,177 - 27,896,414 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	28,535,470 - 28,536,726 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	28,535,582 - 28,536,311 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cholestasis (ISO)

disease of cellular proliferation (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Mammary Neoplasms (ISO)

glaucoma (ISO)

Myocardial Ischemia (ISO)

Neoplasm Metastasis (ISO)

primary pulmonary hypertension (ISO)

pulmonary hypertension (ISO)

Spinal Cord Injuries (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (ISO)

BMP signaling pathway (ISO)

cell differentiation (IEA)

cell-abiotic substrate adhesion (ISO)

cellular response to dopamine (ISO)

cellular response to epidermal growth factor stimulus (ISO)

cellular response to nerve growth factor stimulus (ISO)

cellular response to peptide (ISO)

cellular response to transforming growth factor beta stimulus (ISO)

circadian regulation of gene expression (IEA)

circadian rhythm (ISO)

collagen metabolic process (ISO)

endothelial cell apoptotic process (ISO)

endothelial cell morphogenesis (ISO)

heart development (ISO)

lung morphogenesis (ISO)

lung vasculature development (ISO)

negative regulation of apoptotic process (ISO)

negative regulation of cold-induced thermogenesis (ISO)

negative regulation of dendrite morphogenesis (ISO)

negative regulation of DNA binding (ISO)

negative regulation of DNA-binding transcription factor activity (ISO)

negative regulation of DNA-templated transcription (IEA)

negative regulation of endothelial cell apoptotic process (ISO)

negative regulation of endothelial cell differentiation (ISO)

negative regulation of gene expression (ISO)

negative regulation of osteoblast differentiation (ISO)

negative regulation of protein binding (ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

neuron differentiation (ISO)

positive regulation of actin filament bundle assembly (ISO)

positive regulation of epithelial cell proliferation (ISO)

positive regulation of gene expression (ISO)

protein destabilization (ISO)

regulation of angiogenesis (ISO)

regulation of macromolecule metabolic process (IEA)

regulation of MAPK cascade (ISO)

regulation of nucleobase-containing compound metabolic process (IEA)

regulation of vasculature development (ISO)

response to antibiotic (ISO)

Cellular Component

centrosome (ISO)

cytoplasm (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

identical protein binding (ISO)

proteasome binding (ISO)

protein binding (ISO)

protein dimerization activity (IEA)

transcription factor binding (ISO)

transcription regulator inhibitor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

interleukin-3 signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ID1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	37,296,445 - 37,299,392 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	37,290,399 - 37,292,483 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	27,895,177 - 27,896,414 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	28,535,470 - 28,536,726 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	28,535,582 - 28,536,311 (+)	Ensembl	panpan1.1		panPan2

ID1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	31,605,289 - 31,606,510 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	31,573,014 - 31,606,515 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	30,193,092 - 30,194,313 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	29,656,753 - 29,657,974 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	29,656,752 - 29,657,974	NCBI
Celera	20	26,949,273 - 26,950,494 (+)	NCBI		Celera
Cytogenetic Map	20	q11.21	NCBI
HuRef	20	26,981,781 - 26,983,013 (+)	NCBI		HuRef
CHM1_1	20	30,096,962 - 30,098,194 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	33,329,528 - 33,330,749 (+)	NCBI		T2T-CHM13v2.0

Id1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	152,578,171 - 152,579,330 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	152,578,171 - 152,579,330 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	152,736,251 - 152,737,410 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	152,736,251 - 152,737,410 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	152,562,010 - 152,563,146 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	152,427,715 - 152,428,851 (+)	NCBI		MGSCv36	mm8
Celera	2	158,552,315 - 158,553,451 (+)	NCBI		Celera
Cytogenetic Map	2	H1	NCBI
cM Map	2	75.41	NCBI

Id1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	161,671,525 - 161,672,691 (+)	NCBI		GRCr8
mRatBN7.2	3	141,210,666 - 141,212,420 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	141,211,267 - 141,212,419 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	145,116,210 - 145,117,337 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	153,700,048 - 153,701,175 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	151,439,728 - 151,440,855 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	148,214,623 - 148,216,715 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	148,215,540 - 148,216,718 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	154,619,728 - 154,621,190 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	143,086,162 - 143,087,289 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	142,991,791 - 142,992,906 (+)	NCBI
Celera	3	139,960,608 - 139,961,735 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

Id1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	29,337,757 - 29,339,178 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	29,337,969 - 29,339,178 (-)	NCBI	ChiLan1.0	ChiLan1.0

ID1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	21,094,339 - 21,096,276 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	21,094,755 - 21,096,276 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	20,741,568 - 20,743,501 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	21,780,949 - 21,782,885 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	21,781,704 - 21,782,885 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	21,059,018 - 21,060,951 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	21,163,982 - 21,165,918 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	21,594,218 - 21,596,151 (+)	NCBI		UU_Cfam_GSD_1.0

Id1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	170,179,346 - 170,180,525 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936485	18,610,665 - 18,612,059 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936485	18,610,721 - 18,611,889 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ID1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	35,316,514 - 35,317,736 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	35,316,518 - 35,317,742 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	40,187,160 - 40,188,384 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103247994
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	36,008,660 - 36,009,880 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	36,008,636 - 36,010,017 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	90,944,637 - 90,945,863 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Id1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	896,932 - 898,343 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624741	897,038 - 898,249 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003833403	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000050771 ⟹ ENSPPAP00000027928

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	20	28,535,582 - 28,536,311 (+)	Ensembl

RefSeq Acc Id:

XM_003833403 ⟹ XP_003833451

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	21	37,296,445 - 37,299,392 (+)	NCBI
NHGRI_mPanPan1	20	37,290,399 - 37,292,483 (+)	NCBI
Mhudiblu_PPA_v0	20	27,895,177 - 27,896,414 (+)	NCBI
PanPan1.1	20	28,535,470 - 28,536,726 (+)	NCBI

Sequence:

show sequence

GGCTCCGCACTCTCATTCCACGTTCTTAACCGCTCTATTTTCCGTATCTGCTTCGGGTTTCCAC
CTCATTCTTTCGCTTTGCCCGTTCTGTTTCAGCCCGTCGCCAAGAATCATGAAAGTCGCCAGTG
GCAGCACCGCCACCGCCGCCGCGGGCCCCAGCTGCGCGCTGAAGGCCGGCAAGACAGCGAGCGG
CGCGGGCGAGGTGGTGCGCTGTCTGTCTGAGCAGNNNNNNNNNNNNNNNNNNNNGAGCGTGGCC
ATCTCGCGCTGCGCCGGGGGCGCCGGGGCGCGCCTGCCTGCCCTGCTGGACGAGCAGCAGGTAA
ACGTGCTGCTCTACGACATGAACGGCTGTTACTCACGCCTCAAGGAGCTGGTGCCCACCCTGCC
CCAGAACCGCAAGGTGAGCAAGGTGGAGATTCTCCAGCACGTCATCGACTACATCAGGGACCTG
CAGTTAGAGCTGAACTCGGAATCCGAAGTTGGGACCCCCGGGGGCCGAGGGCTGCCGGTCCGGG
CTCCGCTCAGCACCCTCAACGGCGAGATCAGCGCCCTGACGGCCGAGGCGGCATGCGTTCCTGC
GGACGATCGCATCTTGTGTCGCTGAAGCGCCTCCCCCAGGGACCGGCGGACCCCAGCCATCCAG
GGGGCAAGAGGAATTACGTGCTCTGTGGGTCTCCCCCAACGCGCCTCGCCGGATCTGGGGGAGA
ACAAAACCGATCGGCGGCCACTGCGCCCTTAACTGCATCCAGTCTGGGGCTGAGGCACGGGCGA
GGAGAGGGCGCTCCTCTCTGCACACCTACTAGTCACCAGAGACTTTAGGGGGTGGGATTCCACT
CGTGTGTTTCTATTTTTTGAAAAGCAGACATTTTTAAAAATGGTCACGTTTGGTGCTTCTCAGA
TTTCTGAGGAAATTGCTTTGTATTGTATATTACAATGATCACCGACTGAGAATATTGTTTTACA
ATAGTTCTGTGGGGCTGTTTTTTTGTTATTAAACAAATAATTTAGATGGTGGTAAA

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Protein Sequences


Protein RefSeqs	XP_003833451	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000027928.1

RefSeq Acc Id:	XP_003833451 ⟸ XM_003833403
- UniProtKB:	A0A2R9BFE8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQXXXXXXXSVAISRCAGGAGARLPALL DEQQVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGTPGGR GLPVRAPLSTLNGEISALTAEAACVPADDRILCR hide sequence

Ensembl Acc Id:

ENSPPAP00000027928 ⟸ ENSPPAT00000050771

Protein Domains

bHLH

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000037030	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000050771.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.280.10	UniProtKB/TrEMBL
InterPro	bHLH_dom	UniProtKB/TrEMBL
	DNA-bd_prot-inh	UniProtKB/TrEMBL
	HLH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	ID1	ENTREZGENE
PANTHER	DNA-BINDING PROTEIN INHIBITOR ID-1	UniProtKB/TrEMBL
	PTHR11723	UniProtKB/TrEMBL
Pfam	HLH	UniProtKB/TrEMBL
PROSITE	BHLH	UniProtKB/TrEMBL
SMART	HLH	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47459	UniProtKB/TrEMBL
UniProt	A0A2R9BFE8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-04-25	ID1	inhibitor of DNA binding 1	ID1	inhibitor of DNA binding 1, HLH protein	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

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Imported Disease Annotations - CTD

Imported Annotations - PID (archival)