ID1 (inhibitor of DNA binding 1) - Rat Genome Database

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Gene: ID1 (inhibitor of DNA binding 1) Pan paniscus
Analyze
Symbol: ID1
Name: inhibitor of DNA binding 1
RGD ID: 11817453
Description: ENCODES a protein that exhibits identical protein binding (ortholog); proteasome binding (ortholog); transcription factor binding (ortholog); INVOLVED IN cell-abiotic substrate adhesion (ortholog); cellular response to dopamine (ortholog); cellular response to epidermal growth factor stimulus (ortholog); PARTICIPATES IN interleukin-3 signaling pathway; ASSOCIATED WITH cholestasis (ortholog); disease of cellular proliferation (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN centrosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA-binding protein inhibitor ID-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,296,445 - 37,299,392 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12037,290,399 - 37,292,483 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02027,895,177 - 27,896,414 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12028,535,470 - 28,536,726 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2028,535,582 - 28,536,311 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ID1Bonobocholestasis  ISOId1 (Rattus norvegicus)9068941protein:increased expression:liver and nucleus (rat)RGDPMID:16628634 and REF_RGD_ID:9686088
ID1Bonoboglaucoma  ISOID1 (Homo sapiens)9068941mRNA:increased expression:optic nerve head (human)RGDPMID:28990066 and REF_RGD_ID:155630605
ID1Bonoboprimary pulmonary hypertension  ISOID1 (Homo sapiens)9068941protein:decreased expression:lung and wall of arteriole (human)RGDPMID:20522807 and REF_RGD_ID:9686087
ID1Bonobopulmonary hypertension  ISOId1 (Rattus norvegicus)9068941 RGDPMID:20522807 and REF_RGD_ID:9686087
ID1BonoboSpinal Cord Injuries  ISOId1 (Rattus norvegicus)9068941mRNA:increased expression:spinal cord (rat)RGDPMID:11746449 and REF_RGD_ID:9686138
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ID1Bonobodisease of cellular proliferation  ISOID1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16966095
ID1BonoboExperimental Diabetes Mellitus  ISOID1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16123366
ID1BonoboExperimental Mammary Neoplasms  ISOID1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21283680
ID1BonoboMyocardial Ischemia  ISOID1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16214533
ID1BonoboNeoplasm Metastasis  ISOID1 (Homo sapiens)9068941CTD Direct Evidence: therapeuticCTDPMID:24910342
ID1Bonobotype 2 diabetes mellitus  ISOID1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:16123366


Biological Process
1 to 20 of 44 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ID1Bonoboapoptotic process acts_upstream_ofIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1BonoboBMP signaling pathway acts_upstream_of_or_withinIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1Bonobocell differentiation involved_inIEAPANTHER:PTN000197598150520179 TreeGrafterGO_REF:0000118
ID1Bonobocell-abiotic substrate adhesion  ISOId1 (Rattus norvegicus)9068941 RGDPMID:11600477 and REF_RGD_ID:9686083
ID1Bonobocellular response to dopamine  ISOId1 (Rattus norvegicus)9068941 RGDPMID:20600660 and REF_RGD_ID:9686120
ID1Bonobocellular response to epidermal growth factor stimulus  ISOId1 (Rattus norvegicus)9068941 RGDPMID:7623812 and REF_RGD_ID:9686118
ID1Bonobocellular response to nerve growth factor stimulus  ISOId1 (Rattus norvegicus)9068941 RGDPMID:7623812 and REF_RGD_ID:9686118
ID1Bonobocellular response to peptide  ISOId1 (Rattus norvegicus)9068941beta-endorphinRGDPMID:16706836 and REF_RGD_ID:9686121
ID1Bonobocellular response to transforming growth factor beta stimulus  ISOId1 (Rattus norvegicus)9068941 RGDPMID:16628634 and REF_RGD_ID:9686088
ID1Bonobocircadian regulation of gene expression involved_inIEAPANTHER:PTN000197598150520179 TreeGrafterGO_REF:0000118
ID1Bonobocircadian rhythm involved_inIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1Bonobocollagen metabolic process acts_upstream_of_or_withinIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1Bonoboendothelial cell apoptotic process acts_upstream_ofIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1Bonoboendothelial cell morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1Bonoboheart development acts_upstream_of_or_withinIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1Bonobolung morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1Bonobolung vasculature development acts_upstream_of_or_withinIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1Bonobonegative regulation of apoptotic process  ISOId1 (Rattus norvegicus)9068941 RGDPMID:19137015 and REF_RGD_ID:9686137
ID1Bonobonegative regulation of cold-induced thermogenesis involved_inIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1Bonobonegative regulation of dendrite morphogenesis  ISOId1 (Rattus norvegicus)9068941 RGDPMID:19167333 and REF_RGD_ID:2306262
1 to 20 of 44 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ID1Bonobocentrosome  ISOId1 (Rattus norvegicus)9068941 RGDPMID:19167333 and REF_RGD_ID:2306262
ID1Bonobocytoplasm located_inIEAInterPro:IPR026052150520179 InterProGO_REF:0000002
ID1Bonobocytoplasm located_inIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1Bonobonucleoplasm located_inIEAUniProtKB:P41134 and ensembl:ENSP00000365280150520179 EnsemblGO_REF:0000107
ID1Bonobonucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
ID1Bonobonucleus located_inIEAUniProtKB:P20067 and ensembl:ENSMUSP00000092019150520179 EnsemblGO_REF:0000107
ID1Bonobonucleus located_inIEAPANTHER:PTN000197598150520179 TreeGrafterGO_REF:0000118

Molecular Function
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ID1Bonoboidentical protein binding  ISOId1 (Rattus norvegicus)9068941homodimerizationRGDPMID:8106493 and REF_RGD_ID:729290
ID1Bonoboproteasome binding  ISOPsmd4 (Rattus norvegicus)9068941 RGDPMID:23831032 and REF_RGD_ID:9686139
ID1Bonoboprotein binding enablesISOUniProtKB:Q990819068941 PMID:20211142 and PMID:26496610IntActPMID:20211142 and PMID:26496610
ID1Bonoboprotein binding enablesISOPR:P25801 more ...9068941 PMID:20231428MGIPMID:20231428
ID1Bonoboprotein binding enablesISOPR:Q8BN599068941 PMID:19096764MGIPMID:19096764
ID1Bonoboprotein binding enablesISOPR:P15806 and PR:Q607229068941 PMID:11591653MGIPMID:11591653
ID1Bonoboprotein binding enablesISOUniProtKB:P06396 more ...9068941 PMID:32814053IntActPMID:32814053
ID1Bonoboprotein binding enablesISOUniProtKB:O08785 and UniProtKB:Q9WTL89068941 PMID:20861012UniProtPMID:20861012
ID1Bonoboprotein binding enablesISOUniProtKB:A6NI15 more ...9068941 PMID:32296183IntActPMID:32296183
ID1Bonoboprotein binding enablesISOPR:Q612869068941 PMID:1922066MGIPMID:1922066
ID1Bonoboprotein binding  ISOPsmd4 (Mus musculus)9068941 RGDPMID:23831032 and REF_RGD_ID:9686139
ID1Bonoboprotein binding  ISOId1 (Rattus norvegicus)9068941 RGDPMID:8106493 and REF_RGD_ID:729290
ID1Bonoboprotein binding enablesISOUniProtKB:P354289068941 PMID:17681138UniProtPMID:17681138
ID1Bonoboprotein binding enablesISOUniProtKB:P158849068941 PMID:21988832 more ...IntActPMID:21988832 more ...
ID1Bonoboprotein binding  ISOCdc20 (Rattus norvegicus)9068941 RGDPMID:19167333 and REF_RGD_ID:2306262
ID1Bonoboprotein binding enablesISOUniProtKB:O149369068941 PMID:15694377IntActPMID:15694377
ID1Bonoboprotein binding enablesISOUniProtKB:Q031359068941 PMID:17855368IntActPMID:17855368
ID1Bonoboprotein dimerization activity enablesIEAInterPro:IPR011598 and InterPro:IPR036638150520179 InterProGO_REF:0000002
ID1Bonobotranscription factor binding  ISOTcf3 (Rattus norvegicus)9068941 RGDPMID:7623812 and REF_RGD_ID:9686118
ID1Bonobotranscription factor binding  ISOMyod1 (Mus musculus)9068941 RGDPMID:8106493 and REF_RGD_ID:729290
1 to 20 of 21 rows

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
ID1Bonobointerleukin-3 signaling pathway  ISOID1 (Homo sapiens)9068941 PIDPID:200145
PMID:22301074   PMID:30032202  



ID1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22137,296,445 - 37,299,392 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12037,290,399 - 37,292,483 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02027,895,177 - 27,896,414 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12028,535,470 - 28,536,726 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2028,535,582 - 28,536,311 (+)Ensemblpanpan1.1panPan2
ID1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382031,605,289 - 31,606,510 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2031,573,014 - 31,606,515 (+)EnsemblGRCh38hg38GRCh38
GRCh372030,193,092 - 30,194,313 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362029,656,753 - 29,657,974 (+)NCBINCBI36Build 36hg18NCBI36
Build 342029,656,752 - 29,657,974NCBI
Celera2026,949,273 - 26,950,494 (+)NCBICelera
Cytogenetic Map20q11.21NCBI
HuRef2026,981,781 - 26,983,013 (+)NCBIHuRef
CHM1_12030,096,962 - 30,098,194 (+)NCBICHM1_1
T2T-CHM13v2.02033,329,528 - 33,330,749 (+)NCBIT2T-CHM13v2.0
Id1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392152,578,171 - 152,579,330 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2152,578,171 - 152,579,330 (+)EnsemblGRCm39 Ensembl
GRCm382152,736,251 - 152,737,410 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2152,736,251 - 152,737,410 (+)EnsemblGRCm38mm10GRCm38
MGSCv372152,562,010 - 152,563,146 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362152,427,715 - 152,428,851 (+)NCBIMGSCv36mm8
Celera2158,552,315 - 158,553,451 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map275.41NCBI
Id1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83161,671,525 - 161,672,691 (+)NCBIGRCr8
mRatBN7.23141,210,666 - 141,212,420 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3141,211,267 - 141,212,419 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3145,116,210 - 145,117,337 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03153,700,048 - 153,701,175 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03151,439,728 - 151,440,855 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03148,214,623 - 148,216,715 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3148,215,540 - 148,216,718 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03154,619,728 - 154,621,190 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,086,162 - 143,087,289 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13142,991,791 - 142,992,906 (+)NCBI
Celera3139,960,608 - 139,961,735 (+)NCBICelera
Cytogenetic Map3q41NCBI
Id1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542229,337,757 - 29,339,178 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542229,337,969 - 29,339,178 (-)NCBIChiLan1.0ChiLan1.0
ID1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12421,094,339 - 21,096,276 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2421,094,755 - 21,096,276 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2420,741,568 - 20,743,501 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02421,780,949 - 21,782,885 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2421,781,704 - 21,782,885 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12421,059,018 - 21,060,951 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02421,163,982 - 21,165,918 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02421,594,218 - 21,596,151 (+)NCBIUU_Cfam_GSD_1.0
Id1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640170,179,346 - 170,180,525 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648518,610,665 - 18,612,059 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648518,610,721 - 18,611,889 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ID1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1735,316,514 - 35,317,736 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11735,316,518 - 35,317,742 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21740,187,160 - 40,188,384 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103247994
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1236,008,660 - 36,009,880 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl236,008,636 - 36,010,017 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605090,944,637 - 90,945,863 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Id1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624741896,932 - 898,343 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624741897,038 - 898,249 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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RefSeq Transcripts XM_003833403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000050771   ⟹   ENSPPAP00000027928
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2028,535,582 - 28,536,311 (+)Ensembl
RefSeq Acc Id: XM_003833403   ⟹   XP_003833451
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22137,296,445 - 37,299,392 (+)NCBI
NHGRI_mPanPan12037,290,399 - 37,292,483 (+)NCBI
Mhudiblu_PPA_v02027,895,177 - 27,896,414 (+)NCBI
PanPan1.12028,535,470 - 28,536,726 (+)NCBI
Sequence:
Protein RefSeqs XP_003833451 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000027928.1
RefSeq Acc Id: XP_003833451   ⟸   XM_003833403
- UniProtKB: A0A2R9BFE8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000027928   ⟸   ENSPPAT00000050771
bHLH



1 to 14 of 14 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000037030 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050771.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  DNA-bd_prot-inh UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene ID1 ENTREZGENE
PANTHER DNA-BINDING PROTEIN INHIBITOR ID-1 UniProtKB/TrEMBL
  PTHR11723 UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
UniProt A0A2R9BFE8 ENTREZGENE, UniProtKB/TrEMBL
1 to 14 of 14 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-25 ID1  inhibitor of DNA binding 1  ID1  inhibitor of DNA binding 1, HLH protein  Symbol and/or name change 5135510 APPROVED