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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
interleukin-1 signaling pathway   
Interleukin-1 signaling, primarily via interleukin-1beta, plays important roles in innate and adaptive immune responses. Binding of the processed cytokine to its receptor allows for the recruitment of several accessory and adaptor proteins leading to the activation of NF-kappaB and MAPK signaling cascades. A natural receptor antagonist and a decoy receptor act as regulators of interleukin-1alpha and beta.

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interleukin-18 signaling pathway 
interleukin-33 signaling pathway 
interleukin-6 signaling pathway   
tumor necrosis factor mediated signaling pathway +    

Synonyms
Related Synonyms: Il-1 signaling pathway ;   Interleukin-1 signaling ;   interleukin-1-mediated signaling pathway
Definition Sources: GO:0070498, PID:200089, PMID:20081871, PMID:20303867, PMID:21219179, Reactome:R-HSA-9020702

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