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Ontology Browser

Term:
synaptic vesicle lumen acidification (GO:0097401)
Annotations: Rat: (3) Mouse: (2) Human: (2) Chinchilla: (2) Bonobo: (2) Dog: (2) Squirrel: (2) Pig: (2)
Parent Terms Term With Siblings Child Terms
axonal dopamine secretion +  
calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration 
calcium ion transport into cytosol +   
cardiac muscle cell membrane repolarization +   
energy coupled proton transmembrane transport, against electrochemical gradient +   
energy coupled proton transport, down electrochemical gradient +   
establishment of centrosome localization  
establishment of chromosome localization +   
establishment of ER localization +   
establishment of Golgi localization  
establishment of plastid localization +  
establishment of pole plasm mRNA localization 
establishment of protein localization to mitochondrial membrane +   
establishment of spindle localization +   
establishment of vesicle localization +   
histamine secretion by basophil 
histamine secretion by mast cell +   
histamine secretion by platelet 
insulin secretion involved in cellular response to glucose stimulus +   
intracellular transport +   
iron import into cell +   
leukocyte degranulation +   
neurotransmitter loading into synaptic vesicle +   
neurotransmitter reuptake +   
neurotransmitter secretion +   
platelet degranulation +   
postsynaptic dense core vesicle exocytosis +  
postsynaptic endocytosis +   
postsynaptic neurotransmitter receptor cycle  
presynaptic endocytosis +   
protein secretion by platelet  
proton export across plasma membrane 
regulation of presynaptic cytosolic calcium ion concentration +   
regulation of proton transport +   
regulation of synaptic vesicle cycle +   
serotonin secretion by basophil 
serotonin secretion by mast cell  
serotonin secretion by platelet  
somato-dendritic dopamine secretion 
substrate localization to autophagosome  
synaptic vesicle clustering +   
synaptic vesicle cycle +   
synaptic vesicle exocytosis +   
synaptic vesicle lumen acidification +   
The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.
synaptic vesicle recycling +   

Synonyms
Exact Synonyms: synaptic vesicle lumen pH reduction ;   synaptic vesicle proton loading
Definition Sources: GOC:dsf, PMID:21172605, PMID:22875945

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.