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ONTOLOGY REPORT - ANNOTATIONS


Term:iron import into cell
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Accession:GO:0033212 term browser browse the term
Definition:The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
Synonyms:narrow_synonym: ferrous ion import;   ferrous iron import;   ferrous iron uptake
 related_synonym: iron assimilation
 alt_id: GO:0070627


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iron import into cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc11a2 solute carrier family 11 member 2 JBrowse link 7 142,025,812 142,062,892 RGD:1600115
RGD:13792537
RGD:1624291
G Slc39a14 solute carrier family 39 member 14 JBrowse link 15 51,982,872 52,029,841 RGD:1624291
endocytic hemoglobin import into cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cubn cubilin JBrowse link 17 80,584,921 80,807,181 RGD:2317837
G Lrp2 LDL receptor related protein 2 JBrowse link 3 55,665,153 55,822,484 RGD:2317837
endocytic iron import into cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tfr2 transferrin receptor 2 JBrowse link 12 22,177,382 22,194,330 RGD:1624291
RGD:13792537
iron ion import across plasma membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1600115
G Slc39a8 solute carrier family 39 member 8 JBrowse link 2 241,028,851 241,092,584 RGD:1624291
RGD:15090842
negative regulation of iron ion import across plasma membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Iscu iron-sulfur cluster assembly enzyme JBrowse link 12 48,621,454 48,627,297 RGD:1624291
positive regulation of iron ion import across plasma membrane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    localization 6457
      cellular localization 2931
        establishment of localization in cell 2156
          iron import into cell 9
            endocytic iron import into cell 1
            heme import into cell + 2
            iron ion import across plasma membrane + 4
            reductive iron assimilation 0
            regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter 0
            siderophore-dependent iron import into cell + 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological quality 4252
        homeostatic process 2063
          chemical homeostasis 1322
            ion homeostasis 878
              cellular ion homeostasis 724
                cellular cation homeostasis 710
                  cellular metal ion homeostasis 644
                    cellular transition metal ion homeostasis 116
                      cellular iron ion homeostasis 77
                        iron import into cell 9
                          endocytic iron import into cell 1
                          heme import into cell + 2
                          iron ion import across plasma membrane + 4
                          reductive iron assimilation 0
                          regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter 0
                          siderophore-dependent iron import into cell + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.