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ONTOLOGY REPORT - ANNOTATIONS

Term:synaptic vesicle lumen acidification
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Accession:GO:0097401 term browser browse the term
Definition:The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.
Synonyms:exact_synonym: synaptic vesicle lumen pH reduction;   synaptic vesicle proton loading


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synaptic vesicle lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap1 ATPase H+ transporting accessory protein 1 involved_in ISO
IEA		 (MGI:7316538|PMID:28793259)
GO_REF:0000107		 RGD
Ensembl		 PMID:28793259 GO_REF:0000107 MGI:7316538 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034 		JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 involved_in ISO
IEA		 (MGI:7316538|PMID:28793259)
GO_REF:0000107		 RGD
Ensembl		 PMID:28793259 GO_REF:0000107 MGI:7316538 NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895 		JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr 4:66,760,159...66,842,110
Ensembl chr 4:66,760,159...66,842,110 		JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450 		JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694 		JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 involved_in IC
ISO		 GO_REF:0000111
(MGI:7316538|PMID:28793259)		 SynGO
RGD		 PMID:28793259 GO_REF:0000111 MGI:7316538 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303 		JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr 4:154,022,360...154,044,486
Ensembl chr 4:154,022,358...154,044,584 		JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr 4:58,067,666...58,070,628 JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463 		JBrowse link
G Atp6v1g2 ATPase H+ transporting V1 subunit G2 involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr20:3,587,681...3,591,309
Ensembl chr20:3,587,686...3,590,481 		JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H involved_in ISO (MGI:7316538|PMID:28793259) RGD PMID:28793259 MGI:7316538 NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2447864 (MGI:5006894|PMID:21378974)
(MGI:2182197|PMID:11182090)		 Ensembl
RGD		 PMID:11182090 PMID:21378974 GO_REF:0000107 MGI:2182197 MGI:5006894 NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 acts_upstream_of_or_within ISO MGI:3051945 (MGI:3836822|PMID:19169251) RGD PMID:19169251 MGI:3836822 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    homeostatic process 1915
      cellular homeostasis 945
        neuron cellular homeostasis 82
          synaptic vesicle lumen acidification 18
            negative regulation of synaptic vesicle lumen acidification 0
            positive regulation of synaptic vesicle lumen acidification 0
            regulation of synaptic vesicle lumen acidification + 0
Path 2
Term Annotations click to browse term
  biological_process 19748
    localization 5598
      establishment of localization 4938
        transport 4765
          transmembrane transport 1702
            inorganic ion transmembrane transport 1014
              inorganic cation transmembrane transport 918
                proton transmembrane transport 178
                  synaptic vesicle lumen acidification 18
                    negative regulation of synaptic vesicle lumen acidification 0
                    positive regulation of synaptic vesicle lumen acidification 0
                    regulation of synaptic vesicle lumen acidification + 0
paths to the root