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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic vesicle lumen acidification
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Accession:GO:0097401 term browser browse the term
Definition:The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.
Synonyms:exact_synonym: synaptic vesicle lumen pH reduction;   synaptic vesicle proton loading


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synaptic vesicle lumen acidification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 JBrowse link 4 115,417,100 115,435,754 RGD:1600115
G Clcn3 chloride voltage-gated channel 3 JBrowse link 16 32,448,821 32,520,649 RGD:1624291
G Slc17a7 solute carrier family 17 member 7 JBrowse link 1 101,161,265 101,172,292 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      cellular homeostasis 1045
        neuron cellular homeostasis 44
          synaptic vesicle lumen acidification 3
            negative regulation of synaptic vesicle lumen acidification 0
            positive regulation of synaptic vesicle lumen acidification 0
            regulation of synaptic vesicle lumen acidification + 0
Path 2
Term Annotations click to browse term
  biological_process 19858
    localization 6457
      establishment of localization 4905
        transport 4762
          ion transport 1771
            cation transport 1267
              cation transmembrane transport 898
                inorganic cation transmembrane transport 775
                  proton transmembrane transport 163
                    synaptic vesicle lumen acidification 3
                      negative regulation of synaptic vesicle lumen acidification 0
                      positive regulation of synaptic vesicle lumen acidification 0
                      regulation of synaptic vesicle lumen acidification + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.