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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic vesicle lumen acidification
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Accession:GO:0097401 term browser browse the term
Definition:The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.
Synonyms:exact_synonym: synaptic vesicle lumen pH reduction;   synaptic vesicle proton loading



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synaptic vesicle lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 involved_in IC GO_REF:0000111 SynGO GO_REF:0000111 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475
JBrowse link
G Clcn3 chloride voltage-gated channel 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2447864 (MGI:5006894|PMID:21378974)
(MGI:2182197|PMID:11182090)
Ensembl
RGD
PMID:11182090 PMID:21378974 GO_REF:0000107 MGI:2182197 MGI:5006894 NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Slc17a7 solute carrier family 17 member 7 acts_upstream_of_or_within ISO MGI:3051945 (MGI:3836822|PMID:19169251) RGD PMID:19169251 MGI:3836822 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      cellular homeostasis 1067
        neuron cellular homeostasis 45
          synaptic vesicle lumen acidification 3
            negative regulation of synaptic vesicle lumen acidification 0
            positive regulation of synaptic vesicle lumen acidification 0
            regulation of synaptic vesicle lumen acidification + 0
Path 2
Term Annotations click to browse term
  biological_process 19497
    localization 6488
      establishment of localization 4887
        transport 4725
          ion transport 1651
            cation transport 1271
              cation transmembrane transport 932
                inorganic cation transmembrane transport 810
                  proton transmembrane transport 150
                    synaptic vesicle lumen acidification 3
                      negative regulation of synaptic vesicle lumen acidification 0
                      positive regulation of synaptic vesicle lumen acidification 0
                      regulation of synaptic vesicle lumen acidification + 0
paths to the root