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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic vesicle lumen acidification
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Accession:GO:0097401 term browser browse the term
Definition:The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.
Synonyms:exact_synonym: synaptic vesicle lumen pH reduction;   synaptic vesicle proton loading



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synaptic vesicle lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp6ap1 ATPase H+ transporting accessory protein 1 involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:28793259)
Ensembl
RGD
PMID:28793259 GO_REF:0000107 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 involved_in IEA
ISO
GO_REF:0000107
(PMID:28793259)
Ensembl
RGD
PMID:28793259 GO_REF:0000107 NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895
JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr 4:66,760,163...66,842,126
Ensembl chr 4:66,760,159...66,842,110
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450
JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 involved_in IC
ISO
GO_REF:0000111
(PMID:28793259)
SynGO
RGD
PMID:28793259 GO_REF:0000111 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745
JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr 4:154,022,358...154,044,486
Ensembl chr 4:154,022,358...154,044,584
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr 4:58,067,666...58,070,628 JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 involved_in IBA
ISO
GO_REF:0000033
(PMID:28793259)
GO_Central
RGD
PMID:28793259 GO_REF:0000033 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463
JBrowse link
G Atp6v1g1l1 ATPase H+ transporting V1 subunit G1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:28,663,974...28,664,273
Ensembl chr10:28,663,974...28,664,273
JBrowse link
G Atp6v1g2 ATPase H+ transporting V1 subunit G2 involved_in IBA
ISO
GO_REF:0000033
(PMID:28793259)
GO_Central
RGD
PMID:28793259 GO_REF:0000033 NCBI chr20:3,587,681...3,591,309
Ensembl chr20:3,587,686...3,590,481
JBrowse link
G Atp6v1g3 ATPase H+ transporting V1 subunit G3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:49,800,256...49,825,247
Ensembl chr13:49,794,222...49,825,247
JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H involved_in ISO (PMID:28793259) RGD PMID:28793259 NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962
JBrowse link
G Clcn3 chloride voltage-gated channel 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2447864 (PMID:21378974)
(PMID:11182090)
Ensembl
RGD
PMID:11182090 PMID:21378974 GO_REF:0000107 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Slc17a7 solute carrier family 17 member 7 acts_upstream_of_or_within ISO MGI:3051945 (PMID:19169251) RGD PMID:19169251 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
JBrowse link
regulation of synaptic vesicle lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc9a6 solute carrier family 9 member A6 involved_in IEP
IMP
IDA
PMID:33372133 SynGO PMID:33372133 PMID:33372133 PMID:33372133 RGD:405650253, RGD:405650253, RGD:405650253 NCBI chr  X:134,430,677...134,486,747
Ensembl chr  X:134,420,756...134,485,375
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    homeostatic process 1962
      cellular homeostasis 961
        neuron cellular homeostasis 86
          synaptic vesicle lumen acidification 22
            negative regulation of synaptic vesicle lumen acidification 0
            positive regulation of synaptic vesicle lumen acidification 0
            regulation of synaptic vesicle lumen acidification + 1
Path 2
Term Annotations click to browse term
  biological_process 19872
    localization 5633
      establishment of localization 4939
        transport 4625
          transmembrane transport 1602
            monoatomic ion transmembrane transport 1025
              monoatomic cation transmembrane transport 864
                proton transmembrane transport 171
                  synaptic vesicle lumen acidification 22
                    negative regulation of synaptic vesicle lumen acidification 0
                    positive regulation of synaptic vesicle lumen acidification 0
                    regulation of synaptic vesicle lumen acidification + 1
paths to the root