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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet degranulation
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Accession:GO:0002576 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
Synonyms:exact_synonym: platelet exocytosis


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platelet degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5298337|PMID:20189992)
GO_REF:0000024
RGD
UniProt
PMID:20189992 PMID:21873635 GO_REF:0000024 MGI:5298337, RGD:13792537 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Plek pleckstrin involved_in ISO (PMID:7559487) RGD PMID:7559487 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Stxbp1 syntaxin binding protein 1 involved_in ISO (PMID:12773094) RGD PMID:12773094 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369
JBrowse link
G Tph1 tryptophan hydroxylase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:2683993|PMID:14697203)
UniProt
RGD
PMID:14697203 GO_REF:0000024 MGI:2683993 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
JBrowse link
protein secretion by platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmtn dematin actin binding protein involved_in ISO (MGI:5465511|PMID:23060452) RGD PMID:23060452 MGI:5465511 NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601
JBrowse link
G Plek pleckstrin involved_in ISO (MGI:3844782|PMID:19190246) RGD PMID:19190246 MGI:3844782 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig involved_in ISO (MGI:87668|PMID:9171347) RGD PMID:9171347 MGI:87668 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO MGI:2181608 (MGI:2671726|PMID:12913094) RGD PMID:12913094 MGI:2671726 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623
JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:87668|PMID:9171347)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:9171347 GO_REF:0000024 GO_REF:0000107 MGI:87668 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cellular localization 2965
        establishment of localization in cell 2185
          platelet degranulation 9
            histamine secretion by platelet 0
            protein secretion by platelet 2
            serotonin secretion by platelet 3
Path 2
Term Annotations click to browse term
  biological_process 19492
    localization 6447
      establishment of localization 4864
        transport 4700
          export from cell 1015
            secretion by cell 961
              exocytosis 424
                regulated exocytosis 294
                  platelet degranulation 9
                    histamine secretion by platelet 0
                    protein secretion by platelet 2
                    serotonin secretion by platelet 3
paths to the root