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Term With Siblings |
Child Terms |
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(gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity
(gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity
2'-deoxymugineic-acid 2'-dioxygenase activity
2'-deoxymugineic-acid 3-dioxygenase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity
4-chloro-2-methylphenoxyacetate oxygenase activity
4-coumaroyl 2'-hydroxylase activity
5-methylcytosine dioxygenase activity
6-beta-hydroxyhyoscyamine epoxidase activity
[protein]-asparagine 3-dioxygenase activity
anthocyanidin synthase activity
broad specificity oxidative DNA demethylase activity Catalysis of the reaction: a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2. Catalyzes oxidative demethylation of the DNA base lesions N1- methyladenine, N3-methylcytosine, N1-methylguanine, and N3- methylthymine. Can also act of RNA.
clavaminate synthase activity
codeine O-demethylase activity
cytosine C-5 DNA demethylase activity
deacetoxycephalosporin-C hydroxylase activity
deoxyuridine 1'-dioxygenase activity
deoxyuridine 2'-dioxygenase activity
desacetoxyvindoline 4-hydroxylase activity
DNA N6-methyladenine demethylase activity
flavone synthase activity
flavonol synthase activity
FR-33289 synthase activity
GA20 2,3-desaturase activity
GA5 2,3 epoxidase activity
GA5 3beta-hydroxylase activity
gamma-butyrobetaine dioxygenase activity
gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity
gibberellin 2-beta-dioxygenase activity +
gibberellin 20-oxidase activity
gibberellin 3-beta-dioxygenase activity
gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming)
gibberellin A12,2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A110-forming)
gibberellin A12,oxoglutarate:oxygen oxidoreductase activity
gibberellin A13,oxoglutarate:oxygen oxidoreductase activity
gibberellin A17,oxoglutarate:oxygen oxidoreductase activity
gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity
gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity
gibberellin A25 hydroxylase activity
gibberellin A25,oxoglutarate:oxygen oxidoreductase activity
gibberellin A28,oxoglutarate:oxygen oxidoreductase activity
gibberellin A34,2-oxoglutarate:oxygen oxidoreductase activity
gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity
gibberellin A51,2-oxoglutarate:oxygen oxidoreductase activity
gibberellin A53, 2-oxoglutarate:oxygen oxidoreductase activity
gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming)
gibberellin A9,2-oxoglutarate:oxygen oxidoreductase activity
gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity
gibberellin-44 dioxygenase activity
glutarate dioxygenase activity
histone H3K27me2/H3K27me3 demethylase activity
histone H3K36 demethylase activity +
histone H3K4me/H3K4me2/H3K4me3 demethylase activity
histone H3K56me2/H3K56me3 demethylase activity
histone H3K9me/H3K9me2 demethylase activity
histone H3K9me2/H3K9me3 demethylase activity
histone H3R2 demethylase activity
histone H4K20 demethylase activity
histone H4R3 demethylase activity
hyoscyamine (6S)-dioxygenase activity
hypophosphite dioxygenase activity
L-gamma-glutamyl-L-propargylglycine hydroxylase activity
leucocyanidin oxygenase activity
mugineic-acid 3-dioxygenase activity
naringenin 3-dioxygenase activity
oripavine 6-O-demethylase activity
oxidative RNA demethylase activity +
peptidyl-arginine 3-dioxygenase activity
peptidyl-aspartic acid 3-dioxygenase activity
peptidyl-histidine dioxygenase activity
peptidyl-lysine 3-dioxygenase activity
peptidyl-lysine 4-dioxygenase activity
peptidyl-lysine 5-dioxygenase activity +
peptidyl-proline dioxygenase activity +
phytanoyl-CoA dioxygenase activity
proline 3-hydroxylase activity
sulfonate dioxygenase activity
taurine dioxygenase activity
thebaine 6-O-demethylase activity
thebane O-demethylase activity
thymine dioxygenase activity
trimethyllysine dioxygenase activity
tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity
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| Synonyms |
| Exact Synonyms: |
2-oxoglutarate-dependent DNA demethylase
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| Narrow Synonyms: |
1-ethyladenine demethylase activity
;
5-formylcytosine dioxygenase activity
;
5-hydroxymethylcytosine dioxygenase activity
;
5fC dioxygenase
;
5hmC dioxygenase
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N1-methyladenine demethylase activity
;
N3-methylcytosine demethylase activity
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| Broad Synonyms: |
oxidative DNA demethylase activity
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| Alternate IDs: |
GO:0103051
;
GO:0103052
;
GO:0103053
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| Xrefs: |
EC:1.14.11.33
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MetaCyc:RXN-12353
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RHEA:30299
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Reactome:R-HSA-112118 "Oxidative demethylation of 1-meA damaged DNA by ALKBH2"
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Reactome:R-HSA-112123 "Oxidative demethylation of 1-meA damaged DNA By ALKBH3" |
| Definition Sources: |
PMID:12594517, PMID:16482161, PMID:18775698, PMID:19786499, RHEA:30299 |
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