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ONTOLOGY REPORT - ANNOTATIONS


Term:gamma-butyrobetaine dioxygenase activity
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Accession:GO:0008336 term browser browse the term
Definition:Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O2 = carnitine + CO2 + succinate.
Synonyms:exact_synonym: g-butyrobetaine dioxygenase activity;   gamma-butyrobetaine,2-oxoglutarate dioxygenase activity
 related_synonym: 4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating);   alpha-butyrobetaine hydroxylase activity;   butyrobetaine hydroxylase activity;   gamma-BBH activity;   gamma-butyrobetaine hydroxylase activity
 xref: EC:1.14.11.1;   KEGG_REACTION:R02397;   MetaCyc:1.14.11.1-RXN;   RHEA:24028;   Reactome:R-HSA-71261 "BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA"



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gamma-butyrobetaine dioxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbox1 gamma-butyrobetaine hydroxylase 1 enables TAS
ISS
IEA
ISO
IMP
IBA
PMID:9753662
GO_REF:0000003
(PMID:20599753), (PMID:9753662)
PMID:10526231
(PMID:22999781)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:9753662 PMID:20599753 PMID:22999781 PMID:10526231 PMID:9753662 More... GO_REF:0000003 GO_REF:0000033, RGD:632240, RGD:8554503, RGD:632240 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
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  molecular_function 21088
    catalytic activity 6122
      oxidoreductase activity 868
        dioxygenase activity 100
          2-oxoglutarate-dependent dioxygenase activity 64
            gamma-butyrobetaine dioxygenase activity 1
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