ONTOLOGY REPORT - ANNOTATIONS |
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Term: | peptidyl-lysine 5-dioxygenase activity |
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Accession: | GO:0070815
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Definition: | Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2. |
Synonyms: | exact_synonym: | peptide-lysine 5-dioxygenase activity; protein lysine hydroxylase activity |
| broad_synonym: | lysine hydroxylase activity; lysine,2-oxoglutarate 5-dioxygenase activity; lysine-2-oxoglutarate dioxygenase activity; lysyl hydroxylase activity |
| related_synonym: | peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity; peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity |
| xref: | Reactome:R-HSA-9630022 "JMJD6 dimer hydroxylates lysine residues of U2AF2" |
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Jmjd6 |
jumonji domain containing 6, arginine demethylase and lysine hydroxylase |
enables |
ISS IEA ISO |
GO_REF:0000024 GO_REF:0000107 (PMID:19574390), (PMID:22189873), (PMID:23303181) |
UniProt Ensembl RGD |
PMID:19574390 PMID:22189873 PMID:23303181 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
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Plod1 |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
enables |
IMP IBA IEA IDA ISO |
GO_REF:0000033 GO_REF:0000002 GO_REF:0000003 (PMID:10934207), (PMID:8621606), (PMID:9724729) |
GO_Central InterPro UniProt RGD |
PMID:8621606 PMID:9724729 PMID:10934207 PMID:11714250 PMID:11714250 |
GO_REF:0000002 GO_REF:0000003 GO_REF:0000033, RGD:1599090, RGD:1599090 |
NCBI chr 5:158,340,674...158,367,581
Ensembl chr 5:158,340,490...158,367,620
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Plod2 |
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 |
enables |
IEA IBA ISO |
GO_REF:0000003 GO_REF:0000033 (PMID:10934207) |
UniProt GO_Central RGD |
PMID:10934207 |
GO_REF:0000003 GO_REF:0000033 |
NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
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Plod3 |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 |
enables |
ISO IBA IEA ISS |
(PMID:10934207), (PMID:18298658), (PMID:9582318), (PMID:9724729) (PMID:16447251), (PMID:16467571) GO_REF:0000033 GO_REF:0000107 GO_REF:0000024 |
RGD GO_Central Ensembl UniProt |
PMID:9582318 PMID:9724729 PMID:10934207 PMID:16447251 PMID:16467571 PMID:18298658 More...
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GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 |
NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960
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