Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:peptidyl-lysine 5-dioxygenase activity
go back to main search page
Accession:GO:0070815 term browser browse the term
Definition:Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.
Synonyms:exact_synonym: peptide-lysine 5-dioxygenase activity;   protein lysine hydroxylase activity
 broad_synonym: lysine hydroxylase activity;   lysine,2-oxoglutarate 5-dioxygenase activity;   lysine-2-oxoglutarate dioxygenase activity;   lysyl hydroxylase activity
 related_synonym: peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity;   peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity
 xref: Reactome:R-HSA-9630022 "JMJD6 dimer hydroxylates lysine residues of U2AF2"



show annotations for term's descendants           Sort by:
peptidyl-lysine 5-dioxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase enables ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19574390), (PMID:22189873), (PMID:23303181)
UniProt
Ensembl
RGD
PMID:19574390 PMID:22189873 PMID:23303181 GO_REF:0000024 GO_REF:0000107 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182
JBrowse link
procollagen-lysine 5-dioxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 enables IMP
IBA
IEA
IDA
ISO
GO_REF:0000033
GO_REF:0000002
GO_REF:0000003
(PMID:10934207), (PMID:8621606), (PMID:9724729)
GO_Central
InterPro
UniProt
RGD
PMID:8621606 PMID:9724729 PMID:10934207 PMID:11714250 PMID:11714250 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033, RGD:1599090, RGD:1599090 NCBI chr 5:158,340,674...158,367,581
Ensembl chr 5:158,340,490...158,367,620
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 enables IEA
IBA
ISO
GO_REF:0000003
GO_REF:0000033
(PMID:10934207)
UniProt
GO_Central
RGD
PMID:10934207 GO_REF:0000003 GO_REF:0000033 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 enables ISO
IBA
IEA
ISS
(PMID:10934207), (PMID:18298658), (PMID:9582318), (PMID:9724729)
(PMID:16447251), (PMID:16467571)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
RGD
GO_Central
Ensembl
UniProt
PMID:9582318 PMID:9724729 PMID:10934207 PMID:16447251 PMID:16467571 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      catalytic activity, acting on a protein 2509
        peptidyl-lysine 5-dioxygenase activity 4
          procollagen-lysine 5-dioxygenase activity 3
Path 2
Term Annotations click to browse term
  molecular_function 20634
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 238
          2-oxoglutarate-dependent dioxygenase activity 63
            peptidyl-lysine 5-dioxygenase activity 4
              procollagen-lysine 5-dioxygenase activity 3
paths to the root